ID GDM-1 AC CVCL_1230 SY GDM1 DR CLO; CLO_0003467 DR EFO; EFO_0002183 DR CLDB; cl1446 DR CLDB; cl5541 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; CRL-2627 DR BioSample; SAMN03473160 DR BioSample; SAMN10987916 DR cancercelllines; CVCL_1230 DR Cell_Model_Passport; SIDM01057 DR CGH-DB; 9221-4 DR ChEMBL-Cells; CHEMBL3308198 DR ChEMBL-Targets; CHEMBL2366157 DR Cosmic; 787430 DR Cosmic; 906870 DR Cosmic; 947368 DR Cosmic; 975249 DR Cosmic; 999777 DR Cosmic; 1012067 DR Cosmic; 1177802 DR Cosmic; 1197932 DR Cosmic; 1281313 DR Cosmic; 2089666 DR Cosmic; 2131537 DR Cosmic; 2306196 DR Cosmic-CLP; 906870 DR DepMap; ACH-000081 DR DSMZ; ACC-87 DR DSMZCellDive; ACC-87 DR EGA; EGAS00001000978 DR GDSC; 906870 DR GEO; GSM887023 DR GEO; GSM888093 DR GEO; GSM1446735 DR GEO; GSM1669808 DR IARC_TP53; 21342 DR ICLC; HTL01008 DR IGRhCellID; GDM1 DR LiGeA; CCLE_860 DR LINCS_LDP; LCL-1052 DR PharmacoDB; GDM1_402_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_1230 DR PubChem_Cell_line; CVCL_1230 DR Wikidata; Q54835529 RX DOI=10.1016/B978-0-12-221970-2.50457-5; RX PubMed=6296552; RX PubMed=16408098; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=22460905; RX PubMed=23955599; RX PubMed=25877200; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=30285677; RX PubMed=30629668; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31395879; RX PubMed=35839778; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: TCGA-110-CL cell line panel. CC Population: Caucasian. CC Doubling time: 96-12 hours (PubMed=6296552); ~40-50 hours (DSMZ=ACC-87). CC HLA typing: A*02:01,68:02; B*35:03,38:01; C*04:01,12:03 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=1.71%; Native American=1.16%; East Asian, North=0%; East Asian, South=2.32%; South Asian=9.02%; European, North=27.3%; European, South=58.5% (PubMed=30894373). CC Misspelling: GMD-1; Cosmic=2131537. CC Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. ST Source(s): ATCC=CRL-2627; Cosmic-CLP=906870; DSMZ=ACC-87; PubMed=25877200 ST Amelogenin: X ST CSF1PO: 12 ST D13S317: 11,12 ST D16S539: 12 ST D18S51: 12,13 ST D19S433: 13,15 ST D21S11: 29 ST D2S1338: 17,20 ST D3S1358: 14,15 ST D5S818: 13 ST D7S820: 11,12 ST D8S1179: 14,16 ST FGA: 22,23 ST Penta D: 8,11 ST Penta E: 15,20 ST TH01: 6 ST TPOX: 8,11 ST vWA: 16,17 DI NCIt; C9154; Adult acute myeloid leukemia DI ORDO; Orphanet_519; Acute myeloid leukemia OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 66Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 40 // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=6296552; DOI=10.1016/0145-2126(82)90055-8; RA Ben-Bassat, Hannah RA Korkesh, Aviva RA Voss, Ruth RA Leizerowitz, Rachel RA Polliack, Aaron RT "Establishment and characterization of a new permanent cell line RT (GDM-1) from a patient with myelomonoblastic leukemia."; RL Leuk. Res. 6:743-752(1982). // RX PubMed=31395879; DOI=10.1038/s41467-019-11415-2; PMCID=PMC6687785; RA Yu, Katharine RA Chen, Bin RA Aran, Dvir RA Charalel, Joe RA Yau, Christina RA Wolf, Douglas M. RA van 't Veer, Laura J. RA Butte, Atul Janardhan RA Goldstein, Ted RA Sirota, Marina RT "Comprehensive transcriptomic analysis of cell lines as models of RT primary tumors across 22 tumor types."; RL Nat. Commun. 10:3574.1-3574.11(2019). // RX PubMed=16408098; DOI=10.1038/sj.leu.2404081; RA Quentmeier, Hilmar RA MacLeod, Roderick A.F. RA Zaborski, Margarete RA Drexler, Hans Gunther RT "JAK2 V617F tyrosine kinase mutation in cell lines derived from RT myeloproliferative disorders."; RL Leukemia 20:471-476(2006). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX DOI=10.1016/B978-0-12-221970-2.50457-5; RA Drexler, Hans Gunther RT "The leukemia-lymphoma cell line factsbook."; RL (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=30629668; DOI=10.1371/journal.pone.0210404; PMCID=PMC6328144; RA Uphoff, Cord C. RA Pommerenke, Claudia RA Denkmann, Sabine A. RA Drexler, Hans Gunther RT "Screening human cell lines for viral infections applying RNA-Seq data RT analysis."; RL PLoS ONE 14:e0210404.1-e0210404.22(2019). // RX PubMed=23955599; DOI=10.1038/ng.2731; RA Kon, Ayana RA Shih, Lee-Yung RA Minamino, Masashi RA Sanada, Masashi RA Shiraishi, Yuichi RA Nagata, Yasunobu RA Yoshida, Ken-ichi RA Okuno, Yusuke RA Bando, Masashige RA Nakato, Ryuichiro RA Ishikawa, Shumpei RA Sato-Otsubo, Aiko RA Nagae, Genta RA Nishimoto, Aiko RA Haferlach, Claudia RA Nowak, Daniel RA Sato, Yusuke RA Alpermann, Tamara RA Nagasaki, Masao RA Shimamura, Teppei RA Tanaka, Hiroko RA Chiba, Kenichi RA Yamamoto, Ryo RA Yamaguchi, Tomoyuki RA Otsu, Makoto RA Obara, Naoshi RA Sakata-Yanagimoto, Mamiko RA Nakamaki, Tsuyoshi RA Ishiyama, Ken RA Nolte, Florian RA Hofmann, Wolf-Karsten RA Miyawaki, Shuichi RA Chiba, Shigeru RA Mori, Hiraku RA Nakauchi, Hiromitsu RA Koeffler, Harold Phillip RA Aburatani, Hiroyuki RA Haferlach, Torsten RA Shirahige, Katsuhiko RA Miyano, Satoru RA Ogawa, Seishi RT "Recurrent mutations in multiple components of the cohesin complex in RT myeloid neoplasms."; RL Nat. Genet. 45:1232-1237(2013). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786; RA Tan, Kar-Tong RA Ding, Ling-Wen RA Sun, Qiao-Yang RA Lao, Zhen-Tang RA Chien, Wenwen RA Ren, Xi RA Xiao, Jin-Fen RA Loh, Xin-Yi RA Xu, Liang RA Lill, Michael RA Mayakonda, Anand RA Lin, De-Chen RA Yang, Henry He RA Koeffler, Harold Phillip RT "Profiling the B/T cell receptor repertoire of lymphocyte derived cell RT lines."; RL BMC Cancer 18:940.1-940.13(2018). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). //