ID DV-90 AC CVCL_1184 SY DV90 DR CLO; CLO_0002847 DR EFO; EFO_0006565 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR BioSample; SAMN03473076 DR BioSample; SAMN10988133 DR cancercelllines; CVCL_1184 DR Cell_Model_Passport; SIDM01510 DR ChEMBL-Cells; CHEMBL3308729 DR ChEMBL-Targets; CHEMBL1075437 DR Cosmic; 753553 DR Cosmic; 1146951 DR DepMap; ACH-000925 DR DSMZ; ACC-307 DR DSMZCellDive; ACC-307 DR EGA; EGAS00001000610 DR GDSC; 753553 DR GEO; GSM434301 DR GEO; GSM784284 DR GEO; GSM886990 DR GEO; GSM888059 DR IARC_TP53; 21313 DR IGRhCellID; DV-90_02GEO DR LiGeA; CCLE_820 DR LINCS_LDP; LCL-1636 DR PharmacoDB; DV90_311_2019 DR PRIDE; PXD002556 DR Progenetix; CVCL_1184 DR PubChem_Cell_line; CVCL_1184 DR Wikidata; Q54831597 RX PubMed=7839470; RX PubMed=10908148; RX PubMed=20164919; RX PubMed=22460905; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=26361996; RX PubMed=26589293; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31978347; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Population: Caucasian. CC Doubling time: 24 hours (PubMed=7839470); ~95 hours (DSMZ=ACC-307). CC HLA typing: A*03:01,11:01; B*15:17,35:11; C*04:01,04:01 (PubMed=26589293). CC Microsatellite instability: Instable (MSI) (PubMed=31068700). CC Sequence variation: Mutation; HGNC; HGNC:3431; ERBB3; Simple; p.Val104Met (c.310G>A); ClinVar=VCV000376410; Zygosity=Heterozygous (DepMap=ACH-000925). CC Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (DepMap=ACH-000925). CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.68%; Native American=0%; East Asian, North=2.16%; East Asian, South=0%; South Asian=3.04%; European, North=41.86%; European, South=52.26% (PubMed=30894373). CC Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. ST Source(s): DSMZ=ACC-307; PubMed=25877200 ST Amelogenin: X ST CSF1PO: 10,12 ST D13S317: 10,12 ST D16S539: 11,12 ST D18S51: 13,14 ST D19S433: 13,17 ST D21S11: 31,31.2 ST D2S1338: 17,24 ST D3S1358: 13,16 ST D5S818: 11,13 ST D7S820: 11,14 ST D8S1179: 14,16 ST FGA: 22,24 ST Penta D: 9,10 ST Penta E: 10,13 ST TH01: 7,8 ST TPOX: 8 ST vWA: 14,15 DI NCIt; C3512; Lung adenocarcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 50Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 39 CH CVCL_LM80 ! DV-90-GFP // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=26361996; DOI=10.1016/j.jprot.2015.09.003; RA Grundner-Culemann, Kathrin RA Dybowski, J. Nikolaj RA Klammer, Martin RA Tebbe, Andreas RA Schaab, Christoph RA Daub, Henrik RT "Comparative proteome analysis across non-small cell lung cancer cell RT lines."; RL J. Proteomics 130:1-10(2016). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=10908148; DOI=10.1038/labinvest.3780108; RA Speicher, Michael R. RA Petersen, Simone RA Uhrig, Sabine RA Jentsch, Isabell RA Fauth, Christine RA Eils, Roland RA Petersen, Iver RT "Analysis of chromosomal alterations in non-small cell lung cancer by RT multiplex-FISH, comparative genomic hybridization, and multicolor bar RT coding."; RL Lab. Invest. 80:1031-1041(2000). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin K. RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=7839470; DOI=10.1177/030089169408000513; RA Monti, Franco RA Szymczuk, Stefania RA Chessa, Luciana RA Prudente, Sabrina RA Nicoletti, Giordano RA Fattori, Pier Paolo RA Pini, Emanuela RA Desiderio, Franco RA Pasquini, Enzo RA Tison, Vittorio RA Ravaioli, Alberto RT "Biologic characterization of pleural metastases from lung RT adenocarcinoma: description of the new DV90 cell line."; RL Tumori 80:378-384(1994). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). //