ID   BALL-1
AC   CVCL_1075
SY   Ball-1; Ball 1; BALL1; B-cell Acute Lymphoblastic Leukemia-1
DR   BTO; BTO_0001148
DR   CLO; CLO_0037300
DR   CLO; CLO_0051004
DR   CLO; CLO_0051005
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   BioSample; SAMN03471059
DR   BioSample; SAMN03472350
DR   cancercelllines; CVCL_1075
DR   CCRID; 5301HUM-KCB94007YJ
DR   Cell_Model_Passport; SIDM00287
DR   ChEMBL-Cells; CHEMBL3308839
DR   ChEMBL-Targets; CHEMBL2366269
DR   CLS; 305084
DR   Cosmic; 910705
DR   Cosmic; 919134
DR   Cosmic; 999755
DR   Cosmic; 999762
DR   Cosmic; 1150902
DR   Cosmic-CLP; 910705
DR   DepMap; ACH-002211
DR   DSMZ; ACC-742
DR   DSMZCellDive; ACC-742
DR   EGA; EGAS00001000978
DR   FANTOM5_SSTAR; 10455-106G5
DR   GDSC; 910705
DR   GEO; GSM827223
DR   GEO; GSM1669606
DR   IARC_TP53; 21184
DR   JCRB; JCRB0071
DR   KCB; KCB 94007YJ
DR   LINCS_LDP; LCL-1005
DR   PharmacoDB; BALL1_73_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1075
DR   PubChem_Cell_line; CVCL_1075
DR   RCB; RCB0256
DR   RCB; RCB1882
DR   TKG; TKG 0467
DR   Wikidata; Q54753112
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   DOI=10.11418/jtca1981.15.4_211;
RX   DOI=10.4044/joma1947.92.5-6_763;
RX   PubMed=195075;
RX   PubMed=197412;
RX   PubMed=2985879;
RX   PubMed=3159941;
RX   PubMed=3874327;
RX   PubMed=6582512;
RX   PubMed=8139288;
RX   PubMed=8156010;
RX   PubMed=8957066;
RX   PubMed=9290701;
RX   PubMed=9510473;
RX   PubMed=15901131;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=30894373;
RX   PubMed=35839778;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Japanese.
CC   Doubling time: 80 hours (Note=In RPMI 1640 + 20% HCS), 66 hours (Note=In RPMI 1640 + 20% FCS) (PubMed=195075); ~48-72 hours (DSMZ=ACC-742).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp281Gly (c.842A>G); ClinVar=VCV000141141; Zygosity=Homozygous (PubMed=15901131; Cosmic-CLP=910705).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=81.09%; East Asian, South=18.9%; South Asian=0%; European, North=0%; European, South=0% (PubMed=30894373).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): CCRID=5301HUM-KCB94007YJ; Cosmic-CLP=910705; DSMZ=ACC-742; JCRB=JCRB0071; RCB=RCB0256; TKG=TKG 0467
ST   Amelogenin: X (JCRB=JCRB0071; TKG=TKG 0467)
ST   Amelogenin: X,Y (CCRID=5301HUM-KCB94007YJ; Cosmic-CLP=910705; DSMZ=ACC-742; RCB=RCB0256)
ST   CSF1PO: 10,12
ST   D13S317: 9,12
ST   D16S539: 9
ST   D18S51: 12,13 (CCRID=5301HUM-KCB94007YJ)
ST   D18S51: 13 (DSMZ=ACC-742)
ST   D19S433: 13,15.2 (CCRID=5301HUM-KCB94007YJ)
ST   D19S433: 13,16 (DSMZ=ACC-742)
ST   D21S11: 30
ST   D2S1338: 19,22
ST   D3S1358: 16
ST   D5S818: 10,12,13 (RCB=RCB0256)
ST   D5S818: 10,13 (CCRID=5301HUM-KCB94007YJ; Cosmic-CLP=910705; DSMZ=ACC-742; JCRB=JCRB0071; TKG=TKG 0467)
ST   D7S820: 10,12
ST   D8S1179: 10,14
ST   FGA: 22,23
ST   Penta D: 9,10
ST   Penta E: 14,16
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 14,18
DI   NCIt; C9143; Adult B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   75Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 42
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   DOI=10.11418/jtca1981.15.4_211;
RA   Matsuo, Yoshinobu
RA   Okochi, Ayumi
RA   Ariyasu, Toshio
RA   Iimura, Emi
RA   Ohno, Tadao
RT   "Identification of cell lines with variable numbers of tandem repeat
RT   (VNTR) amplified by polymerase chain reaction.";
RL   Tissue Cult. Res. Commun. 15:211-219(1996).
//
RX   DOI=10.4044/joma1947.92.5-6_763;
RA   Nakamura, Kazuo
RT   "Studies on human leukemic B-cell line, Part I. Establishment and
RT   characterization of human leukemic B-cell line (BALL-1).";
RL   Okayama Igakkai Zasshi 92:763-773(1980).
//
RX   PubMed=195075; DOI=10.1093/jnci/59.1.93;
RA   Hiraki, Shunkichi
RA   Miyoshi, Isao
RA   Masuji, Hiroshi
RA   Kubonishi, Ichiro
RA   Matsuda, Yuzo
RT   "Establishment of an Epstein-Barr virus-determined nuclear
RT   antigen-negative human B-cell line from acute lymphoblastic leukemia.";
RL   J. Natl. Cancer Inst. 59:93-94(1977).
//
RX   PubMed=197412; DOI=10.1038/267843a0;
RA   Miyoshi, Isao
RA   Hiraki, Shunkichi
RA   Tsubota, Teruhiko
RA   Kubonishi, Ichiro
RA   Matsuda, Yuzo
RA   Nakayama, Takashi
RA   Kishimoto, Hirofumi
RA   Kimura, Ikuro
RA   Masuji, Hiroshi
RT   "Human B cell, T cell and null cell leukaemic cell lines derived from
RT   acute lymphoblastic leukaemias.";
RL   Nature 267:843-844(1977).
//
RX   PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- 1.
RT   Carboxylic esterase.";
RL   Leuk. Res. 9:209-229(1985).
//
RX   PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- III.
RT   Beta-hexosaminidase (E.C. 3.2.1.30).";
RL   Leuk. Res. 9:549-559(1985).
//
RX   PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid
RT   phosphatase.";
RL   Leuk. Res. 9:537-548(1985).
//
RX   PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720;
RA   Mattes, Michael Jules
RA   Cordon-Cardo, Carlos
RA   Lewis, John L. Jr.
RA   Old, Lloyd John
RA   Lloyd, Kenneth Oliver
RT   "Cell surface antigens of human ovarian and endometrial carcinoma
RT   defined by mouse monoclonal antibodies.";
RL   Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984).
//
RX   PubMed=8139288; DOI=10.1016/0145-2126(94)90118-x;
RA   Sato, Seitetsu
RA   Honma, Yoshio
RA   Hozumi, Motoo
RA   Hayashi, Yasuhide
RA   Matsuo, Yoshinobu
RA   Shibata, Kiyoshi
RA   Omura, Satoshi
RA   Hino, Ken-ichiro
RA   Tomoyasu, Shigeru
RA   Tsuruoka, Nobuyoshi
RT   "Effects of herbimycin A and its derivatives on growth and
RT   differentiation of Ph1-positive acute lymphoid leukemia cell lines.";
RL   Leuk. Res. 18:221-228(1994).
//
RX   PubMed=8156010; DOI=10.1159/000236736;
RA   Yoshida, Naoko
RA   Ueno, Mika
RA   Saita, Naoki
RA   Hirashima, Mitsuomi
RT   "A B cell lymphoma line, BALL-1 stimulates T cells to produce a unique
RT   eosinophil chemotactic factor.";
RL   Int. Arch. Allergy Immunol. 104 Suppl. 1:9-11(1994).
//
RX   PubMed=8957066; DOI=10.1111/j.1349-7006.1996.tb03112.x; PMCID=PMC5920998;
RA   Kawasaki, Nobuhiro
RA   Matsuo, Yoshinobu
RA   Yoshino, Tadashi
RA   Yanai, Hiroyuki
RA   Oka, Takashi
RA   Teramoto, Norihiro
RA   Liu, Cao
RA   Kondo, Eisaku
RA   Minowada, Jun
RA   Akagi, Tadaatsu
RT   "Metastatic potential of lymphoma/leukemia cell lines in SCID mice is
RT   closely related to expression of CD44.";
RL   Jpn. J. Cancer Res. 87:1070-1077(1996).
//
RX   PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D;
RA   Jia, Li-Qun
RA   Osada, Motonobu
RA   Ishioka, Chikashi
RA   Gamo, Makio
RA   Ikawa, Shuntaro
RA   Suzuki, Takao
RA   Shimodaira, Hideki
RA   Niitani, Tomohito
RA   Kudo, Toshio
RA   Akiyama, Mitoshi
RA   Kimura, Narimiti
RA   Matsuo, Mitsuyoshi
RA   Mizusawa, Hiroshi
RA   Tanaka, Noriho
RA   Koyama, Hideki
RA   Namba, Masayoshi
RA   Kanamaru, Ryunosuke
RA   Kuroki, Toshio
RT   "Screening the p53 status of human cell lines using a yeast functional
RT   assay.";
RL   Mol. Carcinog. 19:243-253(1997).
//
RX   PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x; PMCID=PMC5921588;
RA   Hosoya, Noriko
RA   Hangaishi, Akira
RA   Ogawa, Seishi
RA   Miyagawa, Kiyoshi
RA   Mitani, Kinuko
RA   Yazaki, Yoshio
RA   Hirai, Hisamaru
RT   "Frameshift mutations of the hMSH6 gene in human leukemia cell
RT   lines.";
RL   Jpn. J. Cancer Res. 89:33-39(1998).
//
RX   PubMed=15901131; DOI=10.1016/j.prp.2005.01.002;
RA   Murai, Yoshihiro
RA   Hayashi, Shinichi
RA   Takahashi, Hiroyuki
RA   Tsuneyama, Koichi
RA   Takano, Yasuo
RT   "Correlation between DNA alterations and p53 and p16 protein
RT   expression in cancer cell lines.";
RL   Pathol. Res. Pract. 201:109-115(2005).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, A. Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//