ID   JPX-9
AC   CVCL_0D86
SY   Jpx-9; JPX9; JPX 9-4
DR   cancercelllines; CVCL_0D86
DR   Wikidata; Q54899053
RX   PubMed=2501514;
RX   PubMed=2784206;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P03409; Human T-cell leukemia virus 1 (HTLV-1) Tax.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0065 ! Jurkat
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 05-10-23; Version: 16
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RX   PubMed=2501514; DOI=10.1128/JVI.63.8.3220-3226.1989;
RA   Nagata K., Ohtani K., Nakamura M., Sugamura K.;
RT   "Activation of endogenous c-fos proto-oncogene expression by human
RT   T-cell leukemia virus type I-encoded p40tax protein in the human
RT   T-cell line, Jurkat.";
RL   J. Virol. 63:3220-3226(1989).
//
RX   PubMed=2784206; DOI=10.1093/nar/17.4.1589;
RA   Ohtani K., Nakamura M., Saito S., Nagata K., Sugamura K., Hinuma Y.;
RT   "Electroporation: application to human lymphoid cell lines for stable
RT   introduction of a transactivator gene of human T-cell leukemia virus
RT   type I.";
RL   Nucleic Acids Res. 17:1589-1604(1989).
//