ID   Caki-dTub
AC   CVCL_0B30
DR   BTO; BTO_0005559
DR   Wikidata; Q54808380
RX   CelloPub=CLPUB00226;
RX   PubMed=17009030;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_88246; 2'-deoxytubercidin.
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Leu98Pro (c.293T>C); ClinVar=VCV001502192; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0234 ! Caki-1
SX   Male
AG   49Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 19-12-24; Version: 13
//
RX   CelloPub=CLPUB00226;
RA   Pan B.-F., Nelson J.A.;
RT   "Multidrug resistance and collateral sensitivity in a human renal
RT   carcinoma selected for resistance to 2'-deoxytubercidin.";
RL   UroOncology 1:165-174(2001).
//
RX   PubMed=17009030; DOI=10.1007/s00280-006-0351-1;
RA   Pan B.-F., Nelson J.A.;
RT   "Dihydrodiol dehydrogenase in drug resistance and sensitivity of human
RT   carcinomas.";
RL   Cancer Chemother. Pharmacol. 59:697-702(2007).
//