ID   17-71
AC   CVCL_0B18
SY   1771
DR   GEO; GSM1974773
DR   Wikidata; Q54582320
RX   PubMed=3594482;
RX   PubMed=22236332;
RX   PubMed=23365669;
RX   PubMed=27197945;
RX   PubMed=27257868;
RX   PubMed=31175136;
CC   Part of: FACC canine tumor cell line panel.
CC   Doubling time: 24 hours (PubMed=27257868).
CC   Sequence variation: Mutation; VGNC; 39270; CIC; Simple; p.Pro1551fs (c.4650_4653delCCCT); Zygosity=Heterozygous (PubMed=31175136).
CC   Omics: Array-based CGH.
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Lymph node; UBERON=UBERON_0000027.
ST   Source(s): PubMed=27197945; PubMed=31175136
ST   Dog FHC2010: 231
ST   Dog FHC2054: 147,151
ST   Dog FHC2079: 271
ST   Dog PEZ1: 119,127
ST   Dog PEZ3: 119,139 (PubMed=31175136)
ST   Dog PEZ3: 139 (PubMed=27197945)
ST   Dog PEZ5: 103
ST   Dog PEZ6: 183,191
ST   Dog PEZ8: 236,249
ST   Dog PEZ12: 274,277
ST   Dog PEZ20: 180,192
DI   NCIt; C128121; Canine lymphoma
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 29-06-23; Version: 12
//
RX   PubMed=3594482; DOI=10.1007/BF00205629;
RA   Steplewski Z., Jeglum K.A., Rosales C., Weintraub N.;
RT   "Canine lymphoma-associated antigens defined by murine monoclonal
RT   antibodies.";
RL   Cancer Immunol. Immunother. 24:197-201(1987).
//
RX   PubMed=22236332; DOI=10.1111/j.1476-5829.2011.00299.x;
RA   Seiser E.L., Thomas R., Richards K.L., Kelley M.K., Moore P.,
RA   Suter S.E., Breen M.;
RT   "Reading between the lines: molecular characterization of five widely
RT   used canine lymphoid tumour cell lines.";
RL   Vet. Comp. Oncol. 11:30-50(2013).
//
RX   PubMed=23365669; DOI=10.1371/journal.pone.0054464;
RA   Wells J.W., Evans C.H., Scott M.C., Rutgen B.C., O'Brien T.D.,
RA   Modiano J.F., Cvetkovic G., Tepic S.;
RT   "Arginase treatment prevents the recovery of canine lymphoma and
RT   osteosarcoma cells resistant to the toxic effects of prolonged
RT   arginine deprivation.";
RL   PLoS ONE 8:E54464-E54464(2013).
//
RX   PubMed=27197945; DOI=10.1111/vco.12192;
RA   Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.;
RT   "The Flint Animal Cancer Center (FACC) canine tumour cell line panel:
RT   a resource for veterinary drug discovery, comparative oncology and
RT   translational medicine.";
RL   Vet. Comp. Oncol. 15:481-492(2017).
//
RX   PubMed=27257868; DOI=10.1371/journal.pone.0156689;
RA   Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.;
RT   "Intrinsic radiosensitivity and cellular characterization of 27 canine
RT   cancer cell lines.";
RL   PLoS ONE 11:E0156689-E0156689(2016).
//
RX   PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346;
RA   Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.;
RT   "Identifying candidate druggable targets in canine cancer cell lines
RT   using whole exome sequencing.";
RL   Mol. Cancer Ther. 18:1460-1471(2019).
//