ID   OSCA-02
AC   CVCL_0A74
SY   OSCA-2; OSCA2; OSA2
DR   Wikidata; Q54936594
RX   PubMed=21621658;
RX   PubMed=23365669;
RX   PubMed=36099278;
CC   Omics: Genomics; Whole genome sequencing.
CC   Derived from site: In situ; Bone; UBERON=UBERON_0002481.
CC   Breed/subspecies: Rottweiler; VBO=VBO_0201143.
ST   Source(s): PubMed=36099278
ST   Dog FHC2010: 226,238
ST   Dog FHC2054: 151,155
ST   Dog FHC2079: 287
ST   Dog PEZ1: 108,120
ST   Dog PEZ3: 120
ST   Dog PEZ5: 103
ST   Dog PEZ6: 175,179
ST   Dog PEZ8: 234,238
ST   Dog PEZ12: 274,286
ST   Dog PEZ20: 188
DI   NCIt; C120045; Canine osteosarcoma
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
SX   Male
AG   9Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 10-04-25; Version: 9
//
RX   PubMed=21621658; DOI=10.1016/j.bone.2011.05.008; PMCID=PMC3143255;
RA   Scott M.C., Sarver A.L., Gavin K.J., Thayanithy V., Getzy D.M.,
RA   Newman R.A., Cutter G.R., Lindblad-Toh K., Kisseberth W.C.,
RA   Hunter L.E., Subramanian S., Breen M., Modiano J.F.;
RT   "Molecular subtypes of osteosarcoma identified by reducing tumor
RT   heterogeneity through an interspecies comparative approach.";
RL   Bone 49:356-367(2011).
//
RX   PubMed=23365669; DOI=10.1371/journal.pone.0054464; PMCID=PMC3554772;
RA   Wells J.W., Evans C.H., Scott M.C., Rutgen B.C., O'Brien T.D.,
RA   Modiano J.F., Cvetkovic G., Tepic S.;
RT   "Arginase treatment prevents the recovery of canine lymphoma and
RT   osteosarcoma cells resistant to the toxic effects of prolonged
RT   arginine deprivation.";
RL   PLoS ONE 8:e54464.1-e54464.9(2013).
//
RX   PubMed=36099278; DOI=10.1371/journal.pone.0274383; PMCID=PMC9469990;
RA   Megquier K., Turner-Maier J., Morrill K., Li X., Johnson J.,
RA   Karlsson E.K., London C.A., Gardner H.L.;
RT   "The genomic landscape of canine osteosarcoma cell lines reveals
RT   conserved structural complexity and pathway alterations.";
RL   PLoS ONE 17:e0274383.1-e0274383.18(2022).
//