ID MDA-MB-436 AC CVCL_0623 SY MDA_MB_436; MDA MB 436; MDA-Mb-436; MDA-MB436; MDAMB436; MDA-436; MDA436; MB436; MD Anderson-Metastatic Breast-436 DR BTO; BTO_0001568 DR CLO; CLO_0007639 DR EFO; EFO_0001214 DR CLDB; cl7218 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ArrayExpress; E-TABM-157 DR ArrayExpress; E-TABM-244 DR ATCC; HTB-130 DR BioGRID_ORCS_Cell_line; 553 DR BioSample; SAMN03471588 DR BioSample; SAMN03472712 DR BioSample; SAMN10987901 DR cancercelllines; CVCL_0623 DR CCRID; 1101HUM-PUMC000352 DR CCRID; 3101HUMTCHu184 DR Cell_Model_Passport; SIDM00629 DR ChEMBL-Cells; CHEMBL4295382 DR ChEMBL-Targets; CHEMBL4296465 DR CLS; 300278 DR Cosmic; 809240 DR Cosmic; 871156 DR Cosmic; 897425 DR Cosmic; 904382 DR Cosmic; 934528 DR Cosmic; 949191 DR Cosmic; 979718 DR Cosmic; 1010926 DR Cosmic; 1017165 DR Cosmic; 1027055 DR Cosmic; 1044206 DR Cosmic; 1044222 DR Cosmic; 1046957 DR Cosmic; 1071902 DR Cosmic; 1176604 DR Cosmic; 1287923 DR Cosmic; 1289400 DR Cosmic; 1309008 DR Cosmic; 1434955 DR Cosmic; 1609474 DR Cosmic; 2009513 DR Cosmic; 2164998 DR Cosmic; 2361353 DR Cosmic-CLP; 1240172 DR DepMap; ACH-000573 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 1240172 DR GEO; GSM115100 DR GEO; GSM149985 DR GEO; GSM149993 DR GEO; GSM150001 DR GEO; GSM217589 DR GEO; GSM344354 DR GEO; GSM344404 DR GEO; GSM350541 DR GEO; GSM421878 DR GEO; GSM783954 DR GEO; GSM844600 DR GEO; GSM844601 DR GEO; GSM845397 DR GEO; GSM847416 DR GEO; GSM847496 DR GEO; GSM887299 DR GEO; GSM888374 DR GEO; GSM1008909 DR GEO; GSM1053725 DR GEO; GSM1172982 DR GEO; GSM1214583 DR GEO; GSM1238135 DR GEO; GSM1374658 DR GEO; GSM1374659 DR GEO; GSM1401656 DR GEO; GSM1670085 DR GEO; GSM2258866 DR GEO; GSM2258867 DR GEO; GSM2258868 DR GEO; GSM2258869 DR GEO; GSM2258870 DR GEO; GSM2258871 DR GEO; GSM2258872 DR GEO; GSM2258873 DR GEO; GSM2258874 DR GEO; GSM2258875 DR GEO; GSM2258876 DR GEO; GSM2258877 DR GEO; GSM2258878 DR GEO; GSM2258879 DR GEO; GSM2258880 DR GEO; GSM2258881 DR GEO; GSM2258882 DR GEO; GSM2258883 DR GEO; GSM2258938 DR GEO; GSM2258939 DR GEO; GSM2258940 DR GEO; GSM3161722 DR GEO; GSM3161723 DR IARC_TP53; 18371 DR IARC_TP53; 26994 DR ICLC; HTL11005 DR IZSLER; BS TCL 246 DR LiGeA; CCLE_254 DR LINCS_HMS; 50333 DR LINCS_LDP; LCL-1470 DR PharmacoDB; MDAMB436_905_2019 DR PRIDE; PXD005292 DR PRIDE; PXD008222 DR PRIDE; PXD030304 DR Progenetix; CVCL_0623 DR PubChem_Cell_line; CVCL_0623 DR SLKBase; 3609 DR TOKU-E; 2399 DR Wikidata; Q54904639 RX DOI=10.1016/B978-0-12-333530-2.50009-5; RX DOI=10.25904/1912/1434; RX PubMed=730202; RX PubMed=1961733; RX PubMed=3518877; RX PubMed=7272986; RX PubMed=9288768; RX PubMed=9823299; RX PubMed=10862037; RX PubMed=10969801; RX PubMed=11343771; RX PubMed=15677628; RX PubMed=16397213; RX PubMed=16541312; RX PubMed=17157791; RX PubMed=18516279; RX PubMed=19582160; RX PubMed=19593635; RX PubMed=21778573; RX PubMed=22460905; RX PubMed=22585861; RX PubMed=23151021; RX PubMed=23601657; RX PubMed=24094812; RX PubMed=24162158; RX PubMed=24176112; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25892236; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=28287265; RX PubMed=28889351; RX PubMed=29273624; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; WW Info; LINCS; ICBP43; https://lincs.hms.harvard.edu/resources/reagents/icbp43/ WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255 CC Group: Triple negative breast cancer (TNBC) cell line. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: ICBP43 breast cancer cell line panel. CC Part of: JWGray breast cancer cell line panel. CC Part of: KuDOS 95 cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Population: Caucasian. CC Doubling time: 89.31 hours (JWGray panel). CC HLA typing: A*01:01,01:01; B*08:01,08:01; C*07:01,07:01; DQA1*02:01,05:02; DQB1*04:01,04:01; DRB1*03:01,11:30 (PubMed=26589293). CC Microsatellite instability: Instable (MSI-low) (Sanger). CC Sequence variation: Gene deletion; HGNC; HGNC:3701; FHIT; Zygosity=Homozygous (PubMed=9288768). CC Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; c.5277+1G>A; ClinVar=VCV000037654; Zygosity=Hemizygous; Note=Splice donor mutation (PubMed=16397213; PubMed=19593635). CC Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Gly203fs*9 (c.607_608ins227); Zygosity=Homozygous (PubMed=19593635). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204fs*7 (c.610_612delinsGCGTGTGG); Zygosity=Unspecified (PubMed=16541312; PubMed=28889351). CC Omics: Genomics; ChIP-seq; H2BK120ub. CC Omics: Genomics; ChIP-seq; H3K23ac. CC Omics: Genomics; ChIP-seq; H3K27ac. CC Omics: Genomics; ChIP-seq; H3K27me3. CC Omics: Genomics; ChIP-seq; H3K36me3. CC Omics: Genomics; ChIP-seq; H3K4me1. CC Omics: Genomics; ChIP-seq; H3K4me3. CC Omics: Genomics; ChIP-seq; H3K79me2. CC Omics: Genomics; ChIP-seq; H3K9ac. CC Omics: Genomics; ChIP-seq; H3K9me3. CC Omics: Genomics; ChIP-seq; H4K8ac. CC Omics: Genomics; Chromatin accessibility; ATAC-seq. CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; PTM; Glycoproteome. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=1.41%; Native American=0%; East Asian, North=2.21%; East Asian, South=0%; South Asian=0%; European, North=63.9%; European, South=32.49% (PubMed=30894373). CC Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. ST Source(s): ATCC=HTB-130; CCRID; CLS=300278; Cosmic-CLP=1240172; PubMed=25877200; PubMed=28889351; Technion Genomics Center ST Amelogenin: X ST CSF1PO: 12 ST D10S1248: 13,14 ST D12S391: 20 ST D13S317: 10 ST D16S539: 9 (CLS=300278; Cosmic-CLP=1240172; PubMed=25877200) ST D16S539: 9,11 (ATCC=HTB-130; CCRID; PubMed=28889351; Technion Genomics Center) ST D18S51: 12 ST D19S433: 13 ST D1S1656: 17.3,19.3 ST D21S11: 30,31.2 ST D22S1045: 17 ST D2S1338: 23 ST D2S441: 10 ST D3S1358: 18 ST D5S818: 13 ST D7S820: 10 ST D8S1179: 10,14 ST FGA: 21,24 (CCRID) ST FGA: 24 (ATCC=HTB-130; CLS=300278; PubMed=25877200; Technion Genomics Center) ST Penta D: 9 ST Penta E: 10,12 ST TH01: 9.3 ST TPOX: 8 ST vWA: 14,20 DI NCIt; C4194; Invasive breast carcinoma of no special type OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 43Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 47 CH CVCL_F1RT ! HyCyte MDA-MB-436 KO-hARTN CH CVCL_JY98 ! MDA-MB-436/GFP CH CVCL_JY99 ! MDA-MB-436/RFP // RX PubMed=25892236; DOI=10.1016/j.celrep.2015.03.050; PMCID=PMC4425736; RA Lawrence, Robert T. RA Perez, Elizabeth M. RA Hernandez, Daniel RA Miller, Chris P. RA Haas, Kelsey M. RA Irie, Hanna Y. RA Lee, Su-In RA Blau, C. Anthony RA Villen, Judit RT "The proteomic landscape of triple-negative breast cancer."; RL Cell Rep. 11:630-644(2015). // RX PubMed=24162158; DOI=10.1007/s10549-013-2743-3; PMCID=PMC3832776; RA Prat, Aleix RA Karginova, Olga RA Parker, Joel S. RA Fan, Cheng RA He, Xia-Ping RA Bixby, Lisa M. RA Harrell, J. Chuck RA Roman, Erick RA Adamo, Barbara RA Troester, Melissa A. RA Perou, Charles M. RT "Characterization of cell lines derived from breast cancers and normal RT mammary tissues for the study of the intrinsic molecular subtypes."; RL Breast Cancer Res. Treat. 142:237-255(2013). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590; RA Daemen, Anneleen RA Griffith, Obi L. RA Heiser, Laura M. RA Wang, Nicholas J. RA Enache, Oana M. RA Sanborn, Zachary J. RA Pepin, Francois RA Durinck, Steffen RA Korkola, James E. RA Griffith, Malachi RA Hur, Joe S. RA Huh, Nam RA Chung, Jongsuk RA Cope, Leslie RA Fackler, Mary Jo RA Umbricht, Christopher Benedict RA Sukumar, Saraswati RA Seth, Pankaj RA Sukhatme, Vikas P. RA Jakkula, Lakshmi R. RA Lu, Yi-Ling RA Mills, Gordon B. RA Cho, Raymond J. RA Collisson, Eric A. RA van 't Veer, Laura J. RA Spellman, Paul T. RA Gray, Joe W. RT "Modeling precision treatment of breast cancer."; RL Genome Biol. 14:R110.1-R110.14(2013). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=23151021; DOI=10.1186/1471-2164-13-619; PMCID=PMC3546428; RA Grigoriadis, Anita RA Mackay, Alan RA Noel, Elodie RA Wu, Pei-Jun RA Natrajan, Rachael RA Frankum, Jessica RA Reis-Filho, Jorge Sergio RA Tutt, Andrew N.J. RT "Molecular characterisation of cell line models for triple-negative RT breast cancers."; RL BMC Genomics 13:619.1-619.14(2012). // RX PubMed=28889351; DOI=10.1007/s10549-017-4496-x; RA Saunus, Jodi M. RA Smart, Chanel E. RA Kutasovic, Jamie R. RA Johnston, Rebecca L. RA Kalita-de Croft, Priyakshi RA Miranda, Mariska RA Rozali, Esdy N. RA Vargas, Ana Cristina RA Reid, Lynne E. RA Lorsy, Eva RA Cocciardi, Sibylle RA Seidens, Tatjana RA McCart Reed, Amy Ellen RA Dalley, Andrew J. RA Wockner, Leesa F. RA Johnson, Julie RA Sarkar, Debina RA Askarian-Amiri, Marjan E. RA Simpson, Peter T. RA Khanna, Kum Kum RA Chenevix-Trench, Georgia RA Al-Ejeh, Fares RA Lakhani, Sunil R. RT "Multidimensional phenotyping of breast cancer cell lines to guide RT preclinical research."; RL Breast Cancer Res. Treat. 167:289-301(2018). // RX PubMed=11343771; DOI=10.1016/S0165-4608(00)00387-3; RA Rummukainen, Jaana RA Kytola, Soili RA Karhu, Ritva RA Farnebo, Filip RA Larsson, Catharina RA Isola, Jorma J. RT "Aberrations of chromosome 8 in 16 breast cancer cell lines by RT comparative genomic hybridization, fluorescence in situ RT hybridization, and spectral karyotyping."; RL Cancer Genet. Cytogenet. 126:1-7(2001). // RX PubMed=1961733; DOI=10.1073/pnas.88.23.10657; PMCID=PMC52989; RA Runnebaum, Ingo Bernard RA Nagarajan, Mahalakshmi RA Bowman, Marianne RA Soto, Darya RA Sukumar, Saraswati RT "Mutations in p53 as potential molecular markers for human breast RT cancer."; RL Proc. Natl. Acad. Sci. U.S.A. 88:10657-10661(1991). // RX PubMed=730202; DOI=10.1007/BF02616120; RA Cailleau, Relda Marie RA Olive, Matilde RA Cruciger, Quita V.J. RT "Long-term human breast carcinoma cell lines of metastatic origin: RT preliminary characterization."; RL In Vitro 14:911-915(1978). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=21778573; DOI=10.3233/BD-2010-0307; PMCID=PMC3532890; RA Chavez, Kathryn J. RA Garimella, Sireesha Venkata RA Lipkowitz, Stanley RT "Triple negative breast cancer cell lines: one tool in the search for RT better treatment of triple negative breast cancer."; RL Breast Dis. 32:35-48(2010). // RX PubMed=9288768; RA Ahmadian, Mohsen RA Wistuba, Ignacio Ivan RA Fong, Kwun M. RA Behrens, Carmen RA Kodagoda, Dulmini R. RA Saboorian, M. Hossein RA Shay, Jerry W. RA Tomlinson, Gail E. RA Blum, Joanne L. RA Minna, John D. RA Gazdar, Adi F. RT "Analysis of the FHIT gene and FRA3B region in sporadic breast cancer, RT preneoplastic lesions, and familial breast cancer probands."; RL Cancer Res. 57:3664-3668(1997). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=7272986; DOI=10.1016/0165-4608(81)90057-1; RA Satya-Prakash, Kanithahalli L. RA Pathak, Sen RA Hsu, Tao-Chiuh RA Olive, Matilde RA Cailleau, Relda Marie RT "Cytogenetic analysis on eight human breast tumor cell lines: high RT frequencies of 1q, 11q and HeLa-like marker chromosomes."; RL Cancer Genet. Cytogenet. 3:61-73(1981). // RX DOI=10.1016/B978-0-12-333530-2.50009-5; RA Leibovitz, Albert RT "Cell lines from human breast."; RL (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.161-184; Academic Press; New York; USA (1994). // RX PubMed=9823299; RA Khan, Javed RA Simon, Richard M. RA Bittner, Michael RA Chen, Yi-Dong RA Leighton, Stephen B. RA Pohida, Thomas RA Smith, Paul D. RA Jiang, Yuan RA Gooden, Gerald C. RA Trent, Jeffrey M. RA Meltzer, Paul S. RT "Gene expression profiling of alveolar rhabdomyosarcoma with cDNA RT microarrays."; RL Cancer Res. 58:5009-5013(1998). // RX PubMed=28287265; DOI=10.1021/acs.jproteome.6b00470; PMCID=PMC5557415; RA Yen, Ten-Yang RA Bowen, Spencer RA Yen, Roger RA Piryatinska, Alexandra RA Macher, Bruce A. RA Timpe, Leslie C. RT "Glycoproteins in claudin-low breast cancer cell lines have a unique RT expression profile."; RL J. Proteome Res. 16:1391-1400(2017). // RX PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310; RA Timmerman, Luika A. RA Holton, Thomas RA Yuneva, Mariia RA Louie, Raymond J. RA Padro, Merce RA Daemen, Anneleen RA Hu, Min RA Chan, Denise A. RA Ethier, Stephen P. RA van 't Veer, Laura J. RA Polyak, Kornelia RA McCormick, Frank RA Gray, Joe W. RT "Glutamine sensitivity analysis identifies the xCT antiporter as a RT common triple-negative breast tumor therapeutic target."; RL Cancer Cell 24:450-465(2013). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004; PMCID=PMC2391005; RA Kenny, Paraic A. RA Lee, Genee Y. RA Myers, Connie A. RA Neve, Richard M. RA Semeiks, Jeremy R. RA Spellman, Paul T. RA Lorenz, Kristina RA Lee, Eva H. RA Barcellos-Hoff, Mary Helen RA Petersen, Ole William RA Gray, Joe W. RA Bissell, Mina J. RT "The morphologies of breast cancer cell lines in three-dimensional RT assays correlate with their profiles of gene expression."; RL Mol. Oncol. 1:84-96(2007). // RX PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521; RA Neve, Richard M. RA Chin, Koei RA Fridlyand, Jane RA Yeh, Jennifer RA Baehner, Frederick L. RA Fevr, Tea RA Clark, Laura RA Bayani, Nora RA Coppe, Jean-Philippe RA Tong, Frances RA Speed, Terry RA Spellman, Paul T. RA DeVries, Sandy RA Lapuk, Anna RA Wang, Nick J. RA Kuo, Wen-Lin RA Stilwell, Jackie L. RA Pinkel, Daniel RA Albertson, Donna G. RA Waldman, Frederic M. RA McCormick, Frank RA Dickson, Robert Brent RA Johnson, Michael D. RA Lippman, Marc E. RA Ethier, Stephen P. RA Gazdar, Adi F. RA Gray, Joe W. RT "A collection of breast cancer cell lines for the study of RT functionally distinct cancer subtypes."; RL Cancer Cell 10:515-527(2006). // RX PubMed=29273624; DOI=10.1101/gr.226019.117; PMCID=PMC5793780; RA Franco, Hector L. RA Nagari, Anusha RA Malladi, Venkat S. RA Li, Wen-Qian RA Xi, Yuan-Xin RA Richardson, Dana RA Allton, Kendra L. RA Tanaka, Kaori RA Li, Jing RA Murakami, Shino RA Keyomarsi, Khandan RA Bedford, Mark T. RA Shi, Xiao-Bing RA Li, Wei RA Barton, Michelle Craig RA Dent, Sharon Yoder Roth RA Kraus, W. Lee RT "Enhancer transcription reveals subtype-specific gene expression RT programs controlling breast cancer pathogenesis."; RL Genome Res. 28:159-170(2018). // RX PubMed=15677628; DOI=10.1093/carcin/bgi032; RA Gorringe, Kylie Louise RA Chin, Suet-Feung RA Pharoah, Paul D.P. RA Staines, Joanne M. RA Oliveira, Carla RA Edwards, Paul A.W. RA Caldas, Carlos RT "Evidence that both genetic instability and selection contribute to RT the accumulation of chromosome alterations in cancer."; RL Carcinogenesis 26:923-930(2005). // RX PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396; RA Marcotte, Richard RA Brown, Kevin R. RA Suarez Saiz, Fernando Jose RA Sayad, Azin RA Karamboulas, Konstantina RA Krzyzanowski, Paul M. RA Sircoulomb, Fabrice RA Medrano, Mauricio RA Fedyshyn, Yaroslav RA Koh, Judice Lie-Yong RA van Dyk, Dewald RA Fedyshyn, Bohdana RA Luhova, Marianna RA Brito, Glauber C. RA Vizeacoumar, Franco J. RA Vizeacoumar, Frederick S. RA Datti, Alessandro RA Kasimer, Dahlia RA Buzina, Alla RA Mero, Patricia RA Misquitta, Christine RA Normand, Josee RA Haider, Maliha RA Ketela, Troy RA Wrana, Jeffrey L. RA Rottapel, Robert RA Neel, Benjamin G. RA Moffat, Jason RT "Essential gene profiles in breast, pancreatic, and ovarian cancer RT cells."; RL Cancer Discov. 2:172-189(2012). // RX PubMed=10862037; DOI=10.1002/1098-2264(200007)28:3<308::AID-GCC9>3.0.CO;2-B; RA Kytola, Soili RA Rummukainen, Jaana RA Nordgren, Ann RA Karhu, Ritva RA Farnebo, Filip RA Isola, Jorma J. RA Larsson, Catharina RT "Chromosomal alterations in 15 breast cancer cell lines by comparative RT genomic hybridization and spectral karyotyping."; RL Genes Chromosomes Cancer 28:308-317(2000). // RX PubMed=3518877; DOI=10.3109/07357908609038260; RA Fogh, Jorgen RT "Human tumor lines for cancer research."; RL Cancer Invest. 4:157-184(1986). // RX PubMed=23601657; DOI=10.1186/bcr3415; PMCID=PMC3672661; RA Riaz, Muhammad RA van Jaarsveld, Marijn T.M. RA Hollestelle, Antoinette RA Prager-van der Smissen, Wendy J.C. RA Heine, Anouk A.J. RA Boersma, Antonius W.M. RA Liu, Jing-Jing RA Helmijr, Jean C.A. RA Ozturk, Bahar RA Smid, Marcel RA Wiemer, Erik A.C. RA Foekens, John A. RA Martens, John W.M. RT "miRNA expression profiling of 51 human breast cancer cell lines RT reveals subtype and driver mutation-specific miRNAs."; RL Breast Cancer Res. 15:R33.1-R33.17(2013). // RX PubMed=10969801; RA Forozan, Farahnaz RA Mahlamaki, Eija H. RA Monni, Outi RA Chen, Yi-Dong RA Veldman, Robin RA Jiang, Yuan RA Gooden, Gerald C. RA Ethier, Stephen P. RA Kallioniemi, Anne H. RA Kallioniemi, Olli-Pekka RT "Comparative genomic hybridization analysis of 38 breast cancer cell RT lines: a basis for interpreting complementary DNA microarray data."; RL Cancer Res. 60:4519-4525(2000). // RX PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084; RA Kao, Jessica RA Salari, Keyan RA Bocanegra, Melanie RA Choi, Yoon-La RA Girard, Luc RA Gandhi, Jeet RA Kwei, Kevin A. RA Hernandez-Boussard, Tina RA Wang, Pei RA Gazdar, Adi F. RA Minna, John D. RA Pollack, Jonathan R. RT "Molecular profiling of breast cancer cell lines defines relevant RT tumor models and provides a resource for cancer gene discovery."; RL PLoS ONE 4:e6146.1-e6146.16(2009). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=16541312; DOI=10.1007/s10549-006-9186-z; RA Wasielewski, Marijke RA Elstrodt, Fons RA Klijn, Jan G.M. RA Berns, Els M.J.J. RA Schutte, Mieke RT "Thirteen new p53 gene mutants identified among 41 human breast cancer RT cell lines."; RL Breast Cancer Res. Treat. 99:97-101(2006). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX DOI=10.25904/1912/1434; RA Morrison, Brian J. RT "Breast cancer stem cells: tumourspheres and implications for therapy."; RL Thesis PhD (2010); Griffith University; Brisbane; Australia. // RX PubMed=16397213; DOI=10.1158/0008-5472.CAN-05-2853; RA Elstrodt, Fons RA Hollestelle, Antoinette RA Nagel, Jord H.A. RA Gorin, Michael RA Wasielewski, Marijke RA van den Ouweland, Ans M.W. RA Merajver, Sofia Diana RA Ethier, Stephen P. RA Schutte, Mieke RT "BRCA1 mutation analysis of 41 human breast cancer cell lines reveals RT three new deleterious mutants."; RL Cancer Res. 66:41-45(2006). // RX PubMed=19593635; DOI=10.1007/s10549-009-0460-8; RA Hollestelle, Antoinette RA Nagel, Jord H.A. RA Smid, Marcel RA Lam, Suzanne RA Elstrodt, Fons RA Wasielewski, Marijke RA Ng, Ser Sue RA French, Pim J. RA Peeters, Justine K. RA Rozendaal, Marieke J. RA Riaz, Muhammad RA Koopman, Daphne G. RA ten Hagen, Timo L.M. RA de Leeuw, Bertie H.C.G.M. RA Zwarthoff, Ellen C. RA Teunisse, Amina F.A.S. RA van der Spek, Peter J. RA Klijn, Jan G.M. RA Dinjens, Winand N.M. RA Ethier, Stephen P. RA Clevers, Hans Cornelius RA Jochemsen, Aart G. RA den Bakker, Michael A. RA Foekens, John A. RA Martens, John W.M. RA Schutte, Mieke RT "Distinct gene mutation profiles among luminal-type and basal-type RT breast cancer cell lines."; RL Breast Cancer Res. Treat. 121:53-64(2010). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). //