ID   MDA-MB-436
AC   CVCL_0623
SY   MDA_MB_436; MDA MB 436; MDA-Mb-436; MDA-MB436; MDAMB436; MDA-436; MDA436; MB436; MD Anderson-Metastatic Breast-436
DR   BTO; BTO_0001568
DR   CLO; CLO_0007639
DR   EFO; EFO_0001214
DR   CLDB; cl7218
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ArrayExpress; E-TABM-157
DR   ArrayExpress; E-TABM-244
DR   ATCC; HTB-130
DR   BioGRID_ORCS_Cell_line; 553
DR   BioSample; SAMN03471588
DR   BioSample; SAMN03472712
DR   BioSample; SAMN10987901
DR   cancercelllines; CVCL_0623
DR   CCRID; 1101HUM-PUMC000352
DR   CCRID; 3101HUMTCHu184
DR   Cell_Model_Passport; SIDM00629
DR   ChEMBL-Cells; CHEMBL4295382
DR   ChEMBL-Targets; CHEMBL4296465
DR   CLS; 300278
DR   Cosmic; 809240
DR   Cosmic; 871156
DR   Cosmic; 897425
DR   Cosmic; 904382
DR   Cosmic; 934528
DR   Cosmic; 949191
DR   Cosmic; 979718
DR   Cosmic; 1010926
DR   Cosmic; 1017165
DR   Cosmic; 1027055
DR   Cosmic; 1044206
DR   Cosmic; 1044222
DR   Cosmic; 1046957
DR   Cosmic; 1071902
DR   Cosmic; 1176604
DR   Cosmic; 1287923
DR   Cosmic; 1289400
DR   Cosmic; 1309008
DR   Cosmic; 1434955
DR   Cosmic; 1609474
DR   Cosmic; 2009513
DR   Cosmic; 2164998
DR   Cosmic; 2361353
DR   Cosmic-CLP; 1240172
DR   DepMap; ACH-000573
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 1240172
DR   GEO; GSM115100
DR   GEO; GSM149985
DR   GEO; GSM149993
DR   GEO; GSM150001
DR   GEO; GSM217589
DR   GEO; GSM344354
DR   GEO; GSM344404
DR   GEO; GSM350541
DR   GEO; GSM421878
DR   GEO; GSM783954
DR   GEO; GSM844600
DR   GEO; GSM844601
DR   GEO; GSM845397
DR   GEO; GSM847416
DR   GEO; GSM847496
DR   GEO; GSM887299
DR   GEO; GSM888374
DR   GEO; GSM1008909
DR   GEO; GSM1053725
DR   GEO; GSM1172982
DR   GEO; GSM1214583
DR   GEO; GSM1238135
DR   GEO; GSM1374658
DR   GEO; GSM1374659
DR   GEO; GSM1401656
DR   GEO; GSM1670085
DR   GEO; GSM2258866
DR   GEO; GSM2258867
DR   GEO; GSM2258868
DR   GEO; GSM2258869
DR   GEO; GSM2258870
DR   GEO; GSM2258871
DR   GEO; GSM2258872
DR   GEO; GSM2258873
DR   GEO; GSM2258874
DR   GEO; GSM2258875
DR   GEO; GSM2258876
DR   GEO; GSM2258877
DR   GEO; GSM2258878
DR   GEO; GSM2258879
DR   GEO; GSM2258880
DR   GEO; GSM2258881
DR   GEO; GSM2258882
DR   GEO; GSM2258883
DR   GEO; GSM2258938
DR   GEO; GSM2258939
DR   GEO; GSM2258940
DR   GEO; GSM3161722
DR   GEO; GSM3161723
DR   IARC_TP53; 18371
DR   IARC_TP53; 26994
DR   ICLC; HTL11005
DR   IZSLER; BS TCL 246
DR   LiGeA; CCLE_254
DR   LINCS_HMS; 50333
DR   LINCS_LDP; LCL-1470
DR   PharmacoDB; MDAMB436_905_2019
DR   PRIDE; PXD005292
DR   PRIDE; PXD008222
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0623
DR   PubChem_Cell_line; CVCL_0623
DR   SLKBase; 3609
DR   TOKU-E; 2399
DR   Wikidata; Q54904639
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RX   DOI=10.25904/1912/1434;
RX   PubMed=730202;
RX   PubMed=1961733;
RX   PubMed=3518877;
RX   PubMed=7272986;
RX   PubMed=9288768;
RX   PubMed=9823299;
RX   PubMed=10862037;
RX   PubMed=10969801;
RX   PubMed=11343771;
RX   PubMed=15677628;
RX   PubMed=16397213;
RX   PubMed=16541312;
RX   PubMed=17157791;
RX   PubMed=18516279;
RX   PubMed=19582160;
RX   PubMed=19593635;
RX   PubMed=21778573;
RX   PubMed=22460905;
RX   PubMed=22585861;
RX   PubMed=23151021;
RX   PubMed=23601657;
RX   PubMed=24094812;
RX   PubMed=24162158;
RX   PubMed=24176112;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25892236;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=28287265;
RX   PubMed=28889351;
RX   PubMed=29273624;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=31978347;
RX   PubMed=35839778;
WW   Info; LINCS; ICBP43; https://lincs.hms.harvard.edu/resources/reagents/icbp43/
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: ICBP43 breast cancer cell line panel.
CC   Part of: JWGray breast cancer cell line panel.
CC   Part of: KuDOS 95 cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Caucasian.
CC   Doubling time: 89.31 hours (JWGray panel).
CC   HLA typing: A*01:01,01:01; B*08:01,08:01; C*07:01,07:01; DQA1*02:01,05:02; DQB1*04:01,04:01; DRB1*03:01,11:30 (PubMed=26589293).
CC   Microsatellite instability: Instable (MSI-low) (Sanger).
CC   Sequence variation: Gene deletion; HGNC; HGNC:3701; FHIT; Zygosity=Homozygous (PubMed=9288768).
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; c.5277+1G>A; ClinVar=VCV000037654; Zygosity=Hemizygous; Note=Splice donor mutation (PubMed=16397213; PubMed=19593635).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Gly203fs*9 (c.607_608ins227); Zygosity=Homozygous (PubMed=19593635).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204fs*7 (c.610_612delinsGCGTGTGG); Zygosity=Unspecified (PubMed=16541312; PubMed=28889351).
CC   Omics: Genomics; ChIP-seq; H2BK120ub.
CC   Omics: Genomics; ChIP-seq; H3K23ac.
CC   Omics: Genomics; ChIP-seq; H3K27ac.
CC   Omics: Genomics; ChIP-seq; H3K27me3.
CC   Omics: Genomics; ChIP-seq; H3K36me3.
CC   Omics: Genomics; ChIP-seq; H3K4me1.
CC   Omics: Genomics; ChIP-seq; H3K4me3.
CC   Omics: Genomics; ChIP-seq; H3K79me2.
CC   Omics: Genomics; ChIP-seq; H3K9ac.
CC   Omics: Genomics; ChIP-seq; H3K9me3.
CC   Omics: Genomics; ChIP-seq; H4K8ac.
CC   Omics: Genomics; Chromatin accessibility; ATAC-seq.
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; PTM; Glycoproteome.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=1.41%; Native American=0%; East Asian, North=2.21%; East Asian, South=0%; South Asian=0%; European, North=63.9%; European, South=32.49% (PubMed=30894373).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): ATCC=HTB-130; CCRID; CLS=300278; Cosmic-CLP=1240172; PubMed=25877200; PubMed=28889351; Technion Genomics Center
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 13,14
ST   D12S391: 20
ST   D13S317: 10
ST   D16S539: 9 (CLS=300278; Cosmic-CLP=1240172; PubMed=25877200)
ST   D16S539: 9,11 (ATCC=HTB-130; CCRID; PubMed=28889351; Technion Genomics Center)
ST   D18S51: 12
ST   D19S433: 13
ST   D1S1656: 17.3,19.3
ST   D21S11: 30,31.2
ST   D22S1045: 17
ST   D2S1338: 23
ST   D2S441: 10
ST   D3S1358: 18
ST   D5S818: 13
ST   D7S820: 10
ST   D8S1179: 10,14
ST   FGA: 21,24 (CCRID)
ST   FGA: 24 (ATCC=HTB-130; CLS=300278; PubMed=25877200; Technion Genomics Center)
ST   Penta D: 9
ST   Penta E: 10,12
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 14,20
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   43Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 47
//
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RA   Leibovitz, Albert
RT   "Cell lines from human breast.";
RL   (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.161-184; Academic Press; New York; USA (1994).
//
RX   DOI=10.25904/1912/1434;
RA   Morrison, Brian J.
RT   "Breast cancer stem cells: tumourspheres and implications for therapy.";
RL   Thesis PhD (2010); Griffith University; Brisbane; Australia.
//
RX   PubMed=730202; DOI=10.1007/BF02616120;
RA   Cailleau, Relda Marie
RA   Olive, Matilde
RA   Cruciger, Quita V.J.
RT   "Long-term human breast carcinoma cell lines of metastatic origin:
RT   preliminary characterization.";
RL   In Vitro 14:911-915(1978).
//
RX   PubMed=1961733; DOI=10.1073/pnas.88.23.10657; PMCID=PMC52989;
RA   Runnebaum, Ingo Bernard
RA   Nagarajan, Mahalakshmi
RA   Bowman, Marianne
RA   Soto, Darya
RA   Sukumar, Saraswati
RT   "Mutations in p53 as potential molecular markers for human breast
RT   cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:10657-10661(1991).
//
RX   PubMed=3518877; DOI=10.3109/07357908609038260;
RA   Fogh, Jorgen
RT   "Human tumor lines for cancer research.";
RL   Cancer Invest. 4:157-184(1986).
//
RX   PubMed=7272986; DOI=10.1016/0165-4608(81)90057-1;
RA   Satya-Prakash, Kanithahalli L.
RA   Pathak, Sen
RA   Hsu, Tao-Chiuh
RA   Olive, Matilde
RA   Cailleau, Relda Marie
RT   "Cytogenetic analysis on eight human breast tumor cell lines: high
RT   frequencies of 1q, 11q and HeLa-like marker chromosomes.";
RL   Cancer Genet. Cytogenet. 3:61-73(1981).
//
RX   PubMed=9288768;
RA   Ahmadian, Mohsen
RA   Wistuba, Ignacio Ivan
RA   Fong, Kwun M.
RA   Behrens, Carmen
RA   Kodagoda, Dulmini R.
RA   Saboorian, M. Hossein
RA   Shay, Jerry W.
RA   Tomlinson, Gail E.
RA   Blum, Joanne L.
RA   Minna, John D.
RA   Gazdar, Adi F.
RT   "Analysis of the FHIT gene and FRA3B region in sporadic breast cancer,
RT   preneoplastic lesions, and familial breast cancer probands.";
RL   Cancer Res. 57:3664-3668(1997).
//
RX   PubMed=9823299;
RA   Khan, Javed
RA   Simon, Richard M.
RA   Bittner, Michael
RA   Chen, Yi-Dong
RA   Leighton, Stephen B.
RA   Pohida, Thomas
RA   Smith, Paul D.
RA   Jiang, Yuan
RA   Gooden, Gerald C.
RA   Trent, Jeffrey M.
RA   Meltzer, Paul S.
RT   "Gene expression profiling of alveolar rhabdomyosarcoma with cDNA
RT   microarrays.";
RL   Cancer Res. 58:5009-5013(1998).
//
RX   PubMed=10862037; DOI=10.1002/1098-2264(200007)28:3<308::AID-GCC9>3.0.CO;2-B;
RA   Kytola, Soili
RA   Rummukainen, Jaana
RA   Nordgren, Ann
RA   Karhu, Ritva
RA   Farnebo, Filip
RA   Isola, Jorma J.
RA   Larsson, Catharina
RT   "Chromosomal alterations in 15 breast cancer cell lines by comparative
RT   genomic hybridization and spectral karyotyping.";
RL   Genes Chromosomes Cancer 28:308-317(2000).
//
RX   PubMed=10969801;
RA   Forozan, Farahnaz
RA   Mahlamaki, Eija H.
RA   Monni, Outi
RA   Chen, Yi-Dong
RA   Veldman, Robin
RA   Jiang, Yuan
RA   Gooden, Gerald C.
RA   Ethier, Stephen P.
RA   Kallioniemi, Anne H.
RA   Kallioniemi, Olli-Pekka
RT   "Comparative genomic hybridization analysis of 38 breast cancer cell
RT   lines: a basis for interpreting complementary DNA microarray data.";
RL   Cancer Res. 60:4519-4525(2000).
//
RX   PubMed=11343771; DOI=10.1016/S0165-4608(00)00387-3;
RA   Rummukainen, Jaana
RA   Kytola, Soili
RA   Karhu, Ritva
RA   Farnebo, Filip
RA   Larsson, Catharina
RA   Isola, Jorma J.
RT   "Aberrations of chromosome 8 in 16 breast cancer cell lines by
RT   comparative genomic hybridization, fluorescence in situ
RT   hybridization, and spectral karyotyping.";
RL   Cancer Genet. Cytogenet. 126:1-7(2001).
//
RX   PubMed=15677628; DOI=10.1093/carcin/bgi032;
RA   Gorringe, Kylie Louise
RA   Chin, Suet-Feung
RA   Pharoah, Paul D.P.
RA   Staines, Joanne M.
RA   Oliveira, Carla
RA   Edwards, Paul A.W.
RA   Caldas, Carlos
RT   "Evidence that both genetic instability and selection contribute to
RT   the accumulation of chromosome alterations in cancer.";
RL   Carcinogenesis 26:923-930(2005).
//
RX   PubMed=16397213; DOI=10.1158/0008-5472.CAN-05-2853;
RA   Elstrodt, Fons
RA   Hollestelle, Antoinette
RA   Nagel, Jord H.A.
RA   Gorin, Michael
RA   Wasielewski, Marijke
RA   van den Ouweland, Ans M.W.
RA   Merajver, Sofia Diana
RA   Ethier, Stephen P.
RA   Schutte, Mieke
RT   "BRCA1 mutation analysis of 41 human breast cancer cell lines reveals
RT   three new deleterious mutants.";
RL   Cancer Res. 66:41-45(2006).
//
RX   PubMed=16541312; DOI=10.1007/s10549-006-9186-z;
RA   Wasielewski, Marijke
RA   Elstrodt, Fons
RA   Klijn, Jan G.M.
RA   Berns, Els M.J.J.
RA   Schutte, Mieke
RT   "Thirteen new p53 gene mutants identified among 41 human breast cancer
RT   cell lines.";
RL   Breast Cancer Res. Treat. 99:97-101(2006).
//
RX   PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521;
RA   Neve, Richard M.
RA   Chin, Koei
RA   Fridlyand, Jane
RA   Yeh, Jennifer
RA   Baehner, Frederick L.
RA   Fevr, Tea
RA   Clark, Laura
RA   Bayani, Nora
RA   Coppe, Jean-Philippe
RA   Tong, Frances
RA   Speed, Terry
RA   Spellman, Paul T.
RA   DeVries, Sandy
RA   Lapuk, Anna
RA   Wang, Nick J.
RA   Kuo, Wen-Lin
RA   Stilwell, Jackie L.
RA   Pinkel, Daniel
RA   Albertson, Donna G.
RA   Waldman, Frederic M.
RA   McCormick, Frank
RA   Dickson, Robert Brent
RA   Johnson, Michael D.
RA   Lippman, Marc E.
RA   Ethier, Stephen P.
RA   Gazdar, Adi F.
RA   Gray, Joe W.
RT   "A collection of breast cancer cell lines for the study of
RT   functionally distinct cancer subtypes.";
RL   Cancer Cell 10:515-527(2006).
//
RX   PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004; PMCID=PMC2391005;
RA   Kenny, Paraic A.
RA   Lee, Genee Y.
RA   Myers, Connie A.
RA   Neve, Richard M.
RA   Semeiks, Jeremy R.
RA   Spellman, Paul T.
RA   Lorenz, Kristina
RA   Lee, Eva H.
RA   Barcellos-Hoff, Mary Helen
RA   Petersen, Ole William
RA   Gray, Joe W.
RA   Bissell, Mina J.
RT   "The morphologies of breast cancer cell lines in three-dimensional
RT   assays correlate with their profiles of gene expression.";
RL   Mol. Oncol. 1:84-96(2007).
//
RX   PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084;
RA   Kao, Jessica
RA   Salari, Keyan
RA   Bocanegra, Melanie
RA   Choi, Yoon-La
RA   Girard, Luc
RA   Gandhi, Jeet
RA   Kwei, Kevin A.
RA   Hernandez-Boussard, Tina
RA   Wang, Pei
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Pollack, Jonathan R.
RT   "Molecular profiling of breast cancer cell lines defines relevant
RT   tumor models and provides a resource for cancer gene discovery.";
RL   PLoS ONE 4:e6146.1-e6146.16(2009).
//
RX   PubMed=19593635; DOI=10.1007/s10549-009-0460-8;
RA   Hollestelle, Antoinette
RA   Nagel, Jord H.A.
RA   Smid, Marcel
RA   Lam, Suzanne
RA   Elstrodt, Fons
RA   Wasielewski, Marijke
RA   Ng, Ser Sue
RA   French, Pim J.
RA   Peeters, Justine K.
RA   Rozendaal, Marieke J.
RA   Riaz, Muhammad
RA   Koopman, Daphne G.
RA   ten Hagen, Timo L.M.
RA   de Leeuw, Bertie H.C.G.M.
RA   Zwarthoff, Ellen C.
RA   Teunisse, Amina F.A.S.
RA   van der Spek, Peter J.
RA   Klijn, Jan G.M.
RA   Dinjens, Winand N.M.
RA   Ethier, Stephen P.
RA   Clevers, Hans Cornelius
RA   Jochemsen, Aart G.
RA   den Bakker, Michael A.
RA   Foekens, John A.
RA   Martens, John W.M.
RA   Schutte, Mieke
RT   "Distinct gene mutation profiles among luminal-type and basal-type
RT   breast cancer cell lines.";
RL   Breast Cancer Res. Treat. 121:53-64(2010).
//
RX   PubMed=21778573; DOI=10.3233/BD-2010-0307; PMCID=PMC3532890;
RA   Chavez, Kathryn J.
RA   Garimella, Sireesha V.
RA   Lipkowitz, Stanley
RT   "Triple negative breast cancer cell lines: one tool in the search for
RT   better treatment of triple negative breast cancer.";
RL   Breast Dis. 32:35-48(2010).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura E.
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396;
RA   Marcotte, Richard
RA   Brown, Kevin R.
RA   Suarez Saiz, Fernando Jose
RA   Sayad, Azin
RA   Karamboulas, Konstantina
RA   Krzyzanowski, Paul M.
RA   Sircoulomb, Fabrice
RA   Medrano, Mauricio
RA   Fedyshyn, Yaroslav
RA   Koh, Judice Lie-Yong
RA   van Dyk, Dewald
RA   Fedyshyn, Bohdana
RA   Luhova, Marianna
RA   Brito, Glauber C.
RA   Vizeacoumar, Franco J.
RA   Vizeacoumar, Frederick S.
RA   Datti, Alessandro
RA   Kasimer, Dahlia
RA   Buzina, Alla
RA   Mero, Patricia
RA   Misquitta, Christine
RA   Normand, Josee
RA   Haider, Maliha
RA   Ketela, Troy
RA   Wrana, Jeffrey L.
RA   Rottapel, Robert
RA   Neel, Benjamin G.
RA   Moffat, Jason
RT   "Essential gene profiles in breast, pancreatic, and ovarian cancer
RT   cells.";
RL   Cancer Discov. 2:172-189(2012).
//
RX   PubMed=23151021; DOI=10.1186/1471-2164-13-619; PMCID=PMC3546428;
RA   Grigoriadis, Anita
RA   Mackay, Alan
RA   Noel, Elodie
RA   Wu, Pei-Jun
RA   Natrajan, Rachael
RA   Frankum, Jessica
RA   Reis-Filho, Jorge Sergio
RA   Tutt, Andrew
RT   "Molecular characterisation of cell line models for triple-negative
RT   breast cancers.";
RL   BMC Genomics 13:619.1-619.14(2012).
//
RX   PubMed=23601657; DOI=10.1186/bcr3415; PMCID=PMC3672661;
RA   Riaz, Muhammad
RA   van Jaarsveld, Marijn T.M.
RA   Hollestelle, Antoinette
RA   Prager-van der Smissen, Wendy J.C.
RA   Heine, Anouk A.J.
RA   Boersma, Antonius W.M.
RA   Liu, Jing-Jing
RA   Helmijr, Jean C.A.
RA   Ozturk, Bahar
RA   Smid, Marcel
RA   Wiemer, Erik A.C.
RA   Foekens, John A.
RA   Martens, John W.M.
RT   "miRNA expression profiling of 51 human breast cancer cell lines
RT   reveals subtype and driver mutation-specific miRNAs.";
RL   Breast Cancer Res. 15:R33.1-R33.17(2013).
//
RX   PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310;
RA   Timmerman, Luika A.
RA   Holton, Thomas
RA   Yuneva, Mariia
RA   Louie, Raymond J.
RA   Padro, Merce
RA   Daemen, Anneleen
RA   Hu, Min
RA   Chan, Denise A.
RA   Ethier, Stephen P.
RA   van 't Veer, Laura J.
RA   Polyak, Kornelia
RA   McCormick, Frank
RA   Gray, Joe W.
RT   "Glutamine sensitivity analysis identifies the xCT antiporter as a
RT   common triple-negative breast tumor therapeutic target.";
RL   Cancer Cell 24:450-465(2013).
//
RX   PubMed=24162158; DOI=10.1007/s10549-013-2743-3; PMCID=PMC3832776;
RA   Prat, Aleix
RA   Karginova, Olga
RA   Parker, Joel S.
RA   Fan, Cheng
RA   He, Xia-Ping
RA   Bixby, Lisa M.
RA   Harrell, J. Chuck
RA   Roman, Erick
RA   Adamo, Barbara
RA   Troester, Melissa A.
RA   Perou, Charles M.
RT   "Characterization of cell lines derived from breast cancers and normal
RT   mammary tissues for the study of the intrinsic molecular subtypes.";
RL   Breast Cancer Res. Treat. 142:237-255(2013).
//
RX   PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590;
RA   Daemen, Anneleen
RA   Griffith, Obi L.
RA   Heiser, Laura M.
RA   Wang, Nicholas J.
RA   Enache, Oana M.
RA   Sanborn, Zachary
RA   Pepin, Francois
RA   Durinck, Steffen
RA   Korkola, James E.
RA   Griffith, Malachi
RA   Hur, Joe S.
RA   Huh, Nam
RA   Chung, Jongsuk
RA   Cope, Leslie
RA   Fackler, Mary Jo
RA   Umbricht, Christopher Benedict
RA   Sukumar, Saraswati
RA   Seth, Pankaj
RA   Sukhatme, Vikas P.
RA   Jakkula, Lakshmi R.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Cho, Raymond J.
RA   Collisson, Eric A.
RA   van 't Veer, Laura J.
RA   Spellman, Paul T.
RA   Gray, Joe W.
RT   "Modeling precision treatment of breast cancer.";
RL   Genome Biol. 14:R110.1-R110.14(2013).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=25892236; DOI=10.1016/j.celrep.2015.03.050; PMCID=PMC4425736;
RA   Lawrence, Robert T.
RA   Perez, Elizabeth M.
RA   Hernandez, Daniel
RA   Miller, Chris P.
RA   Haas, Kelsey M.
RA   Irie, Hanna Y.
RA   Lee, Su-In
RA   Blau, C. Anthony
RA   Villen, Judit
RT   "The proteomic landscape of triple-negative breast cancer.";
RL   Cell Rep. 11:630-644(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, A. Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=28287265; DOI=10.1021/acs.jproteome.6b00470; PMCID=PMC5557415;
RA   Yen, Ten-Yang
RA   Bowen, Spencer
RA   Yen, Roger
RA   Piryatinska, Alexandra
RA   Macher, Bruce A.
RA   Timpe, Leslie C.
RT   "Glycoproteins in claudin-low breast cancer cell lines have a unique
RT   expression profile.";
RL   J. Proteome Res. 16:1391-1400(2017).
//
RX   PubMed=28889351; DOI=10.1007/s10549-017-4496-x;
RA   Saunus, Jodi M.
RA   Smart, Chanel E.
RA   Kutasovic, Jamie R.
RA   Johnston, Rebecca L.
RA   Kalita-de Croft, Priyakshi
RA   Miranda, Mariska
RA   Rozali, Esdy N.
RA   Vargas, Ana Cristina
RA   Reid, Lynne E.
RA   Lorsy, Eva
RA   Cocciardi, Sibylle
RA   Seidens, Tatjana
RA   McCart Reed, Amy Ellen
RA   Dalley, Andrew J.
RA   Wockner, Leesa F.
RA   Johnson, Julie
RA   Sarkar, Debina
RA   Askarian-Amiri, Marjan E.
RA   Simpson, Peter T.
RA   Khanna, Kum Kum
RA   Chenevix-Trench, Georgia
RA   Al-Ejeh, Fares
RA   Lakhani, Sunil R.
RT   "Multidimensional phenotyping of breast cancer cell lines to guide
RT   preclinical research.";
RL   Breast Cancer Res. Treat. 167:289-301(2018).
//
RX   PubMed=29273624; DOI=10.1101/gr.226019.117; PMCID=PMC5793780;
RA   Franco, Hector L.
RA   Nagari, Anusha
RA   Malladi, Venkat S.
RA   Li, Wen-Qian
RA   Xi, Yuan-Xin
RA   Richardson, Dana
RA   Allton, Kendra L.
RA   Tanaka, Kaori
RA   Li, Jing
RA   Murakami, Shino
RA   Keyomarsi, Khandan
RA   Bedford, Mark T.
RA   Shi, Xiao-Bing
RA   Li, Wei
RA   Barton, Michelle C.
RA   Dent, Sharon Yoder Roth
RA   Kraus, W. Lee
RT   "Enhancer transcription reveals subtype-specific gene expression
RT   programs controlling breast cancer pathogenesis.";
RL   Genome Res. 28:159-170(2018).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=30971826; DOI=10.1038/s41586-019-1103-9;
RA   Behan, Fiona M.
RA   Iorio, Francesco
RA   Picco, Gabriele
RA   Goncalves, Emanuel
RA   Beaver, Charlotte M.
RA   Migliardi, Giorgia
RA   Santos, Rita
RA   Rao, Yanhua
RA   Sassi, Francesco
RA   Pinnelli, Marika
RA   Ansari, Rizwan
RA   Harper, Sarah
RA   Jackson, David Adam
RA   McRae, Rebecca
RA   Pooley, Rachel
RA   Wilkinson, Piers
RA   van der Meer, Dieudonne J.
RA   Dow, David
RA   Buser-Doepner, Carolyn A.
RA   Bertotti, Andrea
RA   Trusolino, Livio
RA   Stronach, Euan Alexander
RA   Saez-Rodriguez, Julio
RA   Yusa, Kosuke
RA   Garnett, Mathew J.
RT   "Prioritization of cancer therapeutic targets using CRISPR-Cas9
RT   screens.";
RL   Nature 568:511-516(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254;
RA   Nusinow, David Paul
RA   Szpyt, John
RA   Ghandi, Mahmoud
RA   Rose, Christopher M.
RA   McDonald, E. Robert 3rd
RA   Kalocsay, Marian
RA   Jane-Valbuena, Judit
RA   Gelfand, Ellen T.
RA   Schweppe, Devin K.
RA   Jedrychowski, Mark P.
RA   Golji, Javad
RA   Porter, Dale A.
RA   Rejtar, Tomas
RA   Wang, Y. Karen
RA   Kryukov, Gregory V.
RA   Stegmeier, Frank
RA   Erickson, Brian K.
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RA   Gygi, Steven P.
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//