ID MDA-MB-157 AC CVCL_0618 AS CVCL_3740 SY MDA-MB157; MDAMB157; MDA-157; MDA157; MB 157; MB157; MD Anderson-Metastatic Breast-157 DR BTO; BTO_0006218 DR CLO; CLO_0007544 DR CLO; CLO_0007632 DR EFO; EFO_0001206 DR CLDB; cl3400 DR CLDB; cl3401 DR AddexBio; C0006020/4986 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ArrayExpress; E-TABM-157 DR ATCC; CRL-7721 DR ATCC; HTB-24 DR BCRJ; 0319 DR BioGRID_ORCS_Cell_line; 556 DR BioSample; SAMN03472739 DR BioSample; SAMN03473083 DR BioSample; SAMN10988196 DR cancercelllines; CVCL_0618 DR CCRID; 1101HUM-PUMC000077 DR Cell_Model_Passport; SIDM00529 DR ChEMBL-Cells; CHEMBL3308759 DR ChEMBL-Targets; CHEMBL1075496 DR Cosmic; 687492 DR Cosmic; 809234 DR Cosmic; 871144 DR Cosmic; 897421 DR Cosmic; 904375 DR Cosmic; 925338 DR Cosmic; 934535 DR Cosmic; 979714 DR Cosmic; 1010921 DR Cosmic; 1017166 DR Cosmic; 1018462 DR Cosmic; 1027052 DR Cosmic; 1044207 DR Cosmic; 1044228 DR Cosmic; 1046954 DR Cosmic; 1047692 DR Cosmic; 1136372 DR Cosmic; 1176640 DR Cosmic; 1287919 DR Cosmic; 1289393 DR Cosmic; 1477429 DR Cosmic; 1523776 DR Cosmic; 1603217 DR Cosmic; 1609468 DR Cosmic; 1995501 DR Cosmic; 2009506 DR Cosmic; 2301527 DR Cosmic-CLP; 925338 DR DepMap; ACH-000621 DR DepMap; ACH-001120 DR ECACC; 92020422 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 925338 DR GEO; GSM73731 DR GEO; GSM115112 DR GEO; GSM186435 DR GEO; GSM186436 DR GEO; GSM217585 DR GEO; GSM219942 DR GEO; GSM350548 DR GEO; GSM421871 DR GEO; GSM783948 DR GEO; GSM783970 DR GEO; GSM827192 DR GEO; GSM844591 DR GEO; GSM847399 DR GEO; GSM847492 DR GEO; GSM887293 DR GEO; GSM888368 DR GEO; GSM1053729 DR GEO; GSM1172881 DR GEO; GSM1172977 DR GEO; GSM1238139 DR GEO; GSM1374648 DR GEO; GSM1374649 DR GEO; GSM1401671 DR GEO; GSM1670079 DR IARC_TP53; 18370 DR LiGeA; CCLE_925 DR LINCS_HMS; 50324 DR LINCS_HMS; 50328 DR LINCS_LDP; LCL-1484 DR LINCS_LDP; LCL-1916 DR PharmacoDB; MDAMB157_898_2019 DR PRIDE; PXD005292 DR PRIDE; PXD008222 DR PRIDE; PXD030304 DR Progenetix; CVCL_0618 DR PubChem_Cell_line; CVCL_0618 DR SLKBase; 3596 DR Wikidata; Q54904578 RX DOI=10.1016/B978-0-12-333530-2.50009-5; RX PubMed=730202; RX PubMed=833871; RX PubMed=1961733; RX PubMed=3518877; RX PubMed=4412247; RX PubMed=4471183; RX PubMed=9671407; RX PubMed=10862037; RX PubMed=10969801; RX PubMed=11044355; RX PubMed=11343771; RX PubMed=12353263; RX PubMed=12800145; RX PubMed=15153330; RX PubMed=15677628; RX PubMed=16397213; RX PubMed=16541312; RX PubMed=17157791; RX PubMed=19582160; RX PubMed=19593635; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=20679594; RX PubMed=21778573; RX PubMed=22460905; RX PubMed=22585861; RX PubMed=23151021; RX PubMed=23601657; RX PubMed=24094812; RX PubMed=24176112; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25892236; RX PubMed=25960936; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=28287265; RX PubMed=28889351; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; WW Info; LINCS; ICBP43; https://lincs.hms.harvard.edu/resources/reagents/icbp43/ WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Pawefish; -; https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/mda-mb-157.htm WW Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255 WW Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/breast-cancer-xenograft/mda-mb-157-xenograft-model/ CC Group: Triple negative breast cancer (TNBC) cell line. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: ICBP43 breast cancer cell line panel. CC Part of: JWGray breast cancer cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). CC Population: African American. CC Doubling time: 2.8 days (PubMed=9671407); 66.98 hours (JWGray panel). CC HLA typing: A*11:01,68:02; B*15:03,55:02; C*01:02,02:02 (PubMed=25960936). CC HLA typing: A*02:01,30:01; B*53:01,53:01; C*04:01,06:02; DQA1*01:02,03:02; DQB1*06:02,06:02; DRB1*11:09,15:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (PubMed=15677628; Sanger). CC Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Pro42Ser (c.124C>T); ClinVar=VCV000089180; Zygosity=Heterozygous (PubMed=19593635; DepMap=ACH-000621). CC Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Arg644Ser (c.1932G>C); ClinVar=VCV000089233; Zygosity=Heterozygous (PubMed=19593635; DepMap=ACH-000621). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro87fs*53 (c.261_286del26) (p.Ala88Cysfs*52); Zygosity=Homozygous (PubMed=16541312; ATCC=HTB-24; DepMap=ACH-000621). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; PTM; Glycoproteome. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=77.9%; Native American=0%; East Asian, North=4.71%; East Asian, South=0%; South Asian=0%; European, North=1.3%; European, South=16.09% (PubMed=30894373). CC Misspelling: MDA-MB-15; Cosmic=897421. CC Discontinued: BCRJ; 0319; probable. CC Discontinued: DepMap; ACH-001120; true. CC Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. ST Source(s): AddexBio=C0006020/4986; ATCC=CRL-7721; ATCC=HTB-24; CCRID=1101HUM-PUMC000077; Cosmic-CLP=925338; ECACC=92020422; PubMed=20679594; PubMed=25877200; PubMed=28889351 ST Amelogenin: X ST CSF1PO: 10 ST D13S317: 11 (AddexBio=C0006020/4986; ATCC=CRL-7721; CCRID=1101HUM-PUMC000077; Cosmic-CLP=925338; ECACC=92020422; PubMed=20679594; PubMed=25877200; PubMed=28889351) ST D13S317: 11,12 (ATCC=HTB-24) ST D16S539: 11 ST D18S51: 13,16 (ATCC=CRL-7721; ATCC=HTB-24) ST D18S51: 16 (CCRID=1101HUM-PUMC000077; PubMed=25877200) ST D19S433: 13,14.2 (ATCC=CRL-7721; ATCC=HTB-24) ST D19S433: 14.2 (CCRID=1101HUM-PUMC000077) ST D21S11: 31,31.2 ST D2S1338: 25 ST D3S1358: 16 ST D5S818: 12 ST D7S820: 10,11 ST D8S1179: 12,14 ST FGA: 22,23 (ATCC=CRL-7721) ST FGA: 23 (ATCC=HTB-24; CCRID=1101HUM-PUMC000077; PubMed=25877200) ST Penta D: 3.2,9 ST Penta E: 11 ST TH01: 7,8 ST TPOX: 9,11 (AddexBio=C0006020/4986; ATCC=CRL-7721; ATCC=HTB-24; ECACC=92020422; PubMed=20679594; PubMed=25877200; PubMed=28889351) ST TPOX: 11 (CCRID=1101HUM-PUMC000077; Cosmic-CLP=925338) ST vWA: 15 DI NCIt; C4872; Breast carcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 44Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 48 // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590; RA Daemen, Anneleen RA Griffith, Obi L. RA Heiser, Laura M. RA Wang, Nicholas J. RA Enache, Oana M. RA Sanborn, Zachary RA Pepin, Francois RA Durinck, Steffen RA Korkola, James E. RA Griffith, Malachi RA Hur, Joe S. RA Huh, Nam RA Chung, Jongsuk RA Cope, Leslie RA Fackler, Mary Jo RA Umbricht, Christopher Benedict RA Sukumar, Saraswati RA Seth, Pankaj RA Sukhatme, Vikas P. RA Jakkula, Lakshmi R. RA Lu, Yi-Ling RA Mills, Gordon B. RA Cho, Raymond J. RA Collisson, Eric A. RA van 't Veer, Laura J. RA Spellman, Paul T. RA Gray, Joe W. RT "Modeling precision treatment of breast cancer."; RL Genome Biol. 14:R110.1-R110.14(2013). // RX PubMed=9671407; DOI=10.1038/sj.onc.1201814; RA Sweeney, Kimberley J. RA Swarbrick, Alexander RA Sutherland, Robert Lyndsay RA Musgrove, Elizabeth A. RT "Lack of relationship between CDK activity and G1 cyclin expression in RT breast cancer cells."; RL Oncogene 16:2865-2878(1998). // RX PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396; RA Marcotte, Richard RA Brown, Kevin R. RA Suarez Saiz, Fernando Jose RA Sayad, Azin RA Karamboulas, Konstantina RA Krzyzanowski, Paul M. RA Sircoulomb, Fabrice RA Medrano, Mauricio RA Fedyshyn, Yaroslav RA Koh, Judice Lie-Yong RA van Dyk, Dewald RA Fedyshyn, Bohdana RA Luhova, Marianna RA Brito, Glauber C. RA Vizeacoumar, Franco J. RA Vizeacoumar, Frederick S. RA Datti, Alessandro RA Kasimer, Dahlia RA Buzina, Alla RA Mero, Patricia RA Misquitta, Christine RA Normand, Josee RA Haider, Maliha RA Ketela, Troy RA Wrana, Jeffrey L. RA Rottapel, Robert RA Neel, Benjamin G. RA Moffat, Jason RT "Essential gene profiles in breast, pancreatic, and ovarian cancer RT cells."; RL Cancer Discov. 2:172-189(2012). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=10969801; RA Forozan, Farahnaz RA Mahlamaki, Eija H. RA Monni, Outi RA Chen, Yi-Dong RA Veldman, Robin RA Jiang, Yuan RA Gooden, Gerald C. RA Ethier, Stephen P. RA Kallioniemi, Anne H. RA Kallioniemi, Olli-Pekka RT "Comparative genomic hybridization analysis of 38 breast cancer cell RT lines: a basis for interpreting complementary DNA microarray data."; RL Cancer Res. 60:4519-4525(2000). // RX PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310; RA Timmerman, Luika A. RA Holton, Thomas RA Yuneva, Mariia RA Louie, Raymond J. RA Padro, Merce RA Daemen, Anneleen RA Hu, Min RA Chan, Denise A. RA Ethier, Stephen P. RA van 't Veer, Laura J. RA Polyak, Kornelia RA McCormick, Frank RA Gray, Joe W. RT "Glutamine sensitivity analysis identifies the xCT antiporter as a RT common triple-negative breast tumor therapeutic target."; RL Cancer Cell 24:450-465(2013). // RX PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981; RA Boegel, Sebastian RA Lower, Martin RA Bukur, Thomas RA Sahin, Ugur RA Castle, John C. RT "A catalog of HLA type, HLA expression, and neo-epitope candidates in RT human cancer cell lines."; RL OncoImmunology 3:e954893.1-e954893.12(2014). // RX PubMed=4471183; DOI=10.1007/BF02616069; RA Young, Russell K. RA Cailleau, Relda Marie RA Mackay, Bruce RA Reeves, William J. Jr. RT "Establishment of epithelial cell line MDA-MB-157 from metastatic RT pleural effusion of human breast carcinoma."; RL In Vitro 9:239-245(1974). // RX PubMed=11343771; DOI=10.1016/S0165-4608(00)00387-3; RA Rummukainen, Jaana RA Kytola, Soili RA Karhu, Ritva RA Farnebo, Filip RA Larsson, Catharina RA Isola, Jorma J. RT "Aberrations of chromosome 8 in 16 breast cancer cell lines by RT comparative genomic hybridization, fluorescence in situ RT hybridization, and spectral karyotyping."; RL Cancer Genet. Cytogenet. 126:1-7(2001). // RX PubMed=15677628; DOI=10.1093/carcin/bgi032; RA Gorringe, Kylie Louise RA Chin, Suet-Feung RA Pharoah, Paul D.P. RA Staines, Joanne M. RA Oliveira, Carla RA Edwards, Paul A.W. RA Caldas, Carlos RT "Evidence that both genetic instability and selection contribute to RT the accumulation of chromosome alterations in cancer."; RL Carcinogenesis 26:923-930(2005). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=23601657; DOI=10.1186/bcr3415; PMCID=PMC3672661; RA Riaz, Muhammad RA van Jaarsveld, Marijn T.M. RA Hollestelle, Antoinette RA Prager-van der Smissen, Wendy J.C. RA Heine, Anouk A.J. RA Boersma, Antonius W.M. RA Liu, Jing-Jing RA Helmijr, Jean C.A. RA Ozturk, Bahar RA Smid, Marcel RA Wiemer, Erik A.C. RA Foekens, John A. RA Martens, John W.M. RT "miRNA expression profiling of 51 human breast cancer cell lines RT reveals subtype and driver mutation-specific miRNAs."; RL Breast Cancer Res. 15:R33.1-R33.17(2013). // RX PubMed=15153330; DOI=10.1593/neo.3292; PMCID=PMC1502105; RA Watts, George S. RA Oshiro, Marc M. RA Junk, Damian J. RA Wozniak, Ryan J. RA Watterson, Summer J. RA Domann, Frederick E. RA Futscher, Bernard W. RT "The acetyltransferase p300/CBP-associated factor is a p53 target gene RT in breast tumor cells."; RL Neoplasia 6:187-194(2004). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=1961733; DOI=10.1073/pnas.88.23.10657; PMCID=PMC52989; RA Runnebaum, Ingo Bernard RA Nagarajan, Mahalakshmi RA Bowman, Marianne RA Soto, Darya RA Sukumar, Saraswati RT "Mutations in p53 as potential molecular markers for human breast RT cancer."; RL Proc. Natl. Acad. Sci. U.S.A. 88:10657-10661(1991). // RX PubMed=4412247; DOI=10.1093/jnci/53.3.661; PMCID=PMC7364228; RA Cailleau, Relda Marie RA Young, Robert RA Olive, Matilde RA Reeves, William J. Jr. RT "Breast tumor cell lines from pleural effusions."; RL J. Natl. Cancer Inst. 53:661-674(1974). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin K. RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=3518877; DOI=10.3109/07357908609038260; RA Fogh, Jorgen RT "Human tumor lines for cancer research."; RL Cancer Invest. 4:157-184(1986). // RX PubMed=28889351; DOI=10.1007/s10549-017-4496-x; RA Saunus, Jodi M. RA Smart, Chanel E. RA Kutasovic, Jamie R. RA Johnston, Rebecca L. RA Kalita-de Croft, Priyakshi RA Miranda, Mariska RA Rozali, Esdy N. RA Vargas, Ana Cristina RA Reid, Lynne E. RA Lorsy, Eva RA Cocciardi, Sibylle RA Seidens, Tatjana RA McCart Reed, Amy Ellen RA Dalley, Andrew J. RA Wockner, Leesa F. RA Johnson, Julie RA Sarkar, Debina RA Askarian-Amiri, Marjan E. RA Simpson, Peter T. RA Khanna, Kum Kum RA Chenevix-Trench, Georgia RA Al-Ejeh, Fares RA Lakhani, Sunil R. RT "Multidimensional phenotyping of breast cancer cell lines to guide RT preclinical research."; RL Breast Cancer Res. Treat. 167:289-301(2018). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474; RA Gazdar, Adi F. RA Girard, Luc RA Lockwood, William W. RA Lam, Wan L. RA Minna, John D. RT "Lung cancer cell lines as tools for biomedical discovery and RT research."; RL J. Natl. Cancer Inst. 102:1310-1321(2010). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=25892236; DOI=10.1016/j.celrep.2015.03.050; PMCID=PMC4425736; RA Lawrence, Robert T. RA Perez, Elizabeth M. RA Hernandez, Daniel RA Miller, Chris P. RA Haas, Kelsey M. RA Irie, Hanna Y. RA Lee, Su-In RA Blau, C. Anthony RA Villen, Judit RT "The proteomic landscape of triple-negative breast cancer."; RL Cell Rep. 11:630-644(2015). // RX DOI=10.1016/B978-0-12-333530-2.50009-5; RA Leibovitz, Albert RT "Cell lines from human breast."; RL (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.161-184; Academic Press; New York; USA (1994). // RX PubMed=16397213; DOI=10.1158/0008-5472.CAN-05-2853; RA Elstrodt, Fons RA Hollestelle, Antoinette RA Nagel, Jord H.A. RA Gorin, Michael RA Wasielewski, Marijke RA van den Ouweland, Ans M.W. RA Merajver, Sofia Diana RA Ethier, Stephen P. RA Schutte, Mieke RT "BRCA1 mutation analysis of 41 human breast cancer cell lines reveals RT three new deleterious mutants."; RL Cancer Res. 66:41-45(2006). // RX PubMed=12800145; DOI=10.1002/gcc.10218; RA Adelaide, Jose RA Huang, Huai-En RA Murati, Anne RA Alsop, Amber E. RA Orsetti, Beatrice RA Mozziconacci, Marie-Joelle RA Popovici, Cornel RA Ginestier, Christophe RA Letessier, Anne RA Basset, Celine RA Courtay-Cahen, Celine RA Jacquemier, Jocelyne RA Theillet, Charles RA Birnbaum, Daniel RA Edwards, Paul A.W. RA Chaffanet, Max RT "A recurrent chromosome translocation breakpoint in breast and RT pancreatic cancer cell lines targets the neuregulin/NRG1 gene."; RL Genes Chromosomes Cancer 37:333-345(2003). // RX PubMed=21778573; DOI=10.3233/BD-2010-0307; PMCID=PMC3532890; RA Chavez, Kathryn J. RA Garimella, Sireesha V. RA Lipkowitz, Stanley RT "Triple negative breast cancer cell lines: one tool in the search for RT better treatment of triple negative breast cancer."; RL Breast Dis. 32:35-48(2010). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=23151021; DOI=10.1186/1471-2164-13-619; PMCID=PMC3546428; RA Grigoriadis, Anita RA Mackay, Alan RA Noel, Elodie RA Wu, Pei-Jun RA Natrajan, Rachael RA Frankum, Jessica RA Reis-Filho, Jorge Sergio RA Tutt, Andrew RT "Molecular characterisation of cell line models for triple-negative RT breast cancers."; RL BMC Genomics 13:619.1-619.14(2012). // RX PubMed=16541312; DOI=10.1007/s10549-006-9186-z; RA Wasielewski, Marijke RA Elstrodt, Fons RA Klijn, Jan G.M. RA Berns, Els M.J.J. RA Schutte, Mieke RT "Thirteen new p53 gene mutants identified among 41 human breast cancer RT cell lines."; RL Breast Cancer Res. Treat. 99:97-101(2006). // RX PubMed=730202; DOI=10.1007/BF02616120; RA Cailleau, Relda Marie RA Olive, Matilde RA Cruciger, Quita V.J. RT "Long-term human breast carcinoma cell lines of metastatic origin: RT preliminary characterization."; RL In Vitro 14:911-915(1978). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, A. Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521; RA Neve, Richard M. RA Chin, Koei RA Fridlyand, Jane RA Yeh, Jennifer RA Baehner, Frederick L. RA Fevr, Tea RA Clark, Laura RA Bayani, Nora RA Coppe, Jean-Philippe RA Tong, Frances RA Speed, Terry RA Spellman, Paul T. RA DeVries, Sandy RA Lapuk, Anna RA Wang, Nick J. RA Kuo, Wen-Lin RA Stilwell, Jackie L. RA Pinkel, Daniel RA Albertson, Donna G. RA Waldman, Frederic M. RA McCormick, Frank RA Dickson, Robert Brent RA Johnson, Michael D. RA Lippman, Marc E. RA Ethier, Stephen P. RA Gazdar, Adi F. RA Gray, Joe W. RT "A collection of breast cancer cell lines for the study of RT functionally distinct cancer subtypes."; RL Cancer Cell 10:515-527(2006). // RX PubMed=11044355; DOI=10.1054/bjoc.2000.1458; PMCID=PMC2408781; RA Davidson, Jeffrey M. RA Gorringe, Kylie Louise RA Chin, Suet-Feung RA Orsetti, Beatrice RA Besret, C. RA Courtay-Cahen, Celine RA Roberts, Ian RA Theillet, Charles RA Caldas, Carlos RA Edwards, Paul A.W. RT "Molecular cytogenetic analysis of breast cancer cell lines."; RL Br. J. Cancer 83:1309-1317(2000). // RX PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084; RA Kao, Jessica RA Salari, Keyan RA Bocanegra, Melanie RA Choi, Yoon-La RA Girard, Luc RA Gandhi, Jeet RA Kwei, Kevin A. RA Hernandez-Boussard, Tina RA Wang, Pei RA Gazdar, Adi F. RA Minna, John D. RA Pollack, Jonathan R. RT "Molecular profiling of breast cancer cell lines defines relevant RT tumor models and provides a resource for cancer gene discovery."; RL PLoS ONE 4:e6146.1-e6146.16(2009). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=19593635; DOI=10.1007/s10549-009-0460-8; RA Hollestelle, Antoinette RA Nagel, Jord H.A. RA Smid, Marcel RA Lam, Suzanne RA Elstrodt, Fons RA Wasielewski, Marijke RA Ng, Ser Sue RA French, Pim J. RA Peeters, Justine K. RA Rozendaal, Marieke J. RA Riaz, Muhammad RA Koopman, Daphne G. RA ten Hagen, Timo L.M. RA de Leeuw, Bertie H.C.G.M. RA Zwarthoff, Ellen C. RA Teunisse, Amina F.A.S. RA van der Spek, Peter J. RA Klijn, Jan G.M. RA Dinjens, Winand N.M. RA Ethier, Stephen P. RA Clevers, Hans Cornelius RA Jochemsen, Aart G. RA den Bakker, Michael A. RA Foekens, John A. RA Martens, John W.M. RA Schutte, Mieke RT "Distinct gene mutation profiles among luminal-type and basal-type RT breast cancer cell lines."; RL Breast Cancer Res. Treat. 121:53-64(2010). // RX PubMed=10862037; DOI=10.1002/1098-2264(200007)28:3<308::AID-GCC9>3.0.CO;2-B; RA Kytola, Soili RA Rummukainen, Jaana RA Nordgren, Ann RA Karhu, Ritva RA Farnebo, Filip RA Isola, Jorma J. RA Larsson, Catharina RT "Chromosomal alterations in 15 breast cancer cell lines by comparative RT genomic hybridization and spectral karyotyping."; RL Genes Chromosomes Cancer 28:308-317(2000). // RX PubMed=12353263; DOI=10.1002/gcc.10107; RA Popovici, Cornel RA Basset, Celine RA Bertucci, Francois RA Orsetti, Beatrice RA Adelaide, Jose RA Mozziconacci, Marie-Joelle RA Conte, Nathalie RA Murati, Anne RA Ginestier, Christophe RA Charafe-Jauffret, Emmanuelle RA Ethier, Stephen P. RA Lafage-Pochitaloff, Marina RA Theillet, Charles RA Birnbaum, Daniel RA Chaffanet, Max RT "Reciprocal translocations in breast tumor cell lines: cloning of a RT t(3;20) that targets the FHIT gene."; RL Genes Chromosomes Cancer 35:204-218(2002). // RX PubMed=28287265; DOI=10.1021/acs.jproteome.6b00470; PMCID=PMC5557415; RA Yen, Ten-Yang RA Bowen, Spencer RA Yen, Roger RA Piryatinska, Alexandra RA Macher, Bruce A. RA Timpe, Leslie C. RT "Glycoproteins in claudin-low breast cancer cell lines have a unique RT expression profile."; RL J. Proteome Res. 16:1391-1400(2017). // RX PubMed=833871; DOI=10.1093/jnci/58.2.209; RA Fogh, Jorgen RA Wright, William C. RA Loveless, James D. RT "Absence of HeLa cell contamination in 169 cell lines derived from RT human tumors."; RL J. Natl. Cancer Inst. 58:209-214(1977). //