ID   MDA-MB-157
AC   CVCL_0618
AS   CVCL_3740
SY   MDA-MB157; MDAMB157; MDA-157; MDA157; MB 157; MB157; MD Anderson-Metastatic Breast-157
DR   BTO; BTO_0006218
DR   CLO; CLO_0007544
DR   CLO; CLO_0007632
DR   EFO; EFO_0001206
DR   CLDB; cl3400
DR   CLDB; cl3401
DR   AddexBio; C0006020/4986
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ArrayExpress; E-TABM-157
DR   ATCC; CRL-7721
DR   ATCC; HTB-24
DR   BCRJ; 0319
DR   BioGRID_ORCS_Cell_line; 556
DR   BioSample; SAMN03472739
DR   BioSample; SAMN03473083
DR   BioSample; SAMN10988196
DR   cancercelllines; CVCL_0618
DR   CCRID; 1101HUM-PUMC000077
DR   Cell_Model_Passport; SIDM00529
DR   ChEMBL-Cells; CHEMBL3308759
DR   ChEMBL-Targets; CHEMBL1075496
DR   Cosmic; 687492
DR   Cosmic; 809234
DR   Cosmic; 871144
DR   Cosmic; 897421
DR   Cosmic; 904375
DR   Cosmic; 925338
DR   Cosmic; 934535
DR   Cosmic; 979714
DR   Cosmic; 1010921
DR   Cosmic; 1017166
DR   Cosmic; 1018462
DR   Cosmic; 1027052
DR   Cosmic; 1044207
DR   Cosmic; 1044228
DR   Cosmic; 1046954
DR   Cosmic; 1047692
DR   Cosmic; 1136372
DR   Cosmic; 1176640
DR   Cosmic; 1287919
DR   Cosmic; 1289393
DR   Cosmic; 1477429
DR   Cosmic; 1523776
DR   Cosmic; 1603217
DR   Cosmic; 1609468
DR   Cosmic; 1995501
DR   Cosmic; 2009506
DR   Cosmic; 2301527
DR   Cosmic-CLP; 925338
DR   DepMap; ACH-000621
DR   DepMap; ACH-001120
DR   ECACC; 92020422
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 925338
DR   GEO; GSM73731
DR   GEO; GSM115112
DR   GEO; GSM186435
DR   GEO; GSM186436
DR   GEO; GSM217585
DR   GEO; GSM219942
DR   GEO; GSM350548
DR   GEO; GSM421871
DR   GEO; GSM783948
DR   GEO; GSM783970
DR   GEO; GSM827192
DR   GEO; GSM844591
DR   GEO; GSM847399
DR   GEO; GSM847492
DR   GEO; GSM887293
DR   GEO; GSM888368
DR   GEO; GSM1053729
DR   GEO; GSM1172881
DR   GEO; GSM1172977
DR   GEO; GSM1238139
DR   GEO; GSM1374648
DR   GEO; GSM1374649
DR   GEO; GSM1401671
DR   GEO; GSM1670079
DR   IARC_TP53; 18370
DR   LiGeA; CCLE_925
DR   LINCS_HMS; 50324
DR   LINCS_HMS; 50328
DR   LINCS_LDP; LCL-1484
DR   LINCS_LDP; LCL-1916
DR   PharmacoDB; MDAMB157_898_2019
DR   PRIDE; PXD005292
DR   PRIDE; PXD008222
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0618
DR   PubChem_Cell_line; CVCL_0618
DR   SLKBase; 3596
DR   Wikidata; Q54904578
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RX   PubMed=730202;
RX   PubMed=833871;
RX   PubMed=1961733;
RX   PubMed=3518877;
RX   PubMed=4412247;
RX   PubMed=4471183;
RX   PubMed=9671407;
RX   PubMed=10862037;
RX   PubMed=10969801;
RX   PubMed=11044355;
RX   PubMed=11343771;
RX   PubMed=12353263;
RX   PubMed=12800145;
RX   PubMed=15153330;
RX   PubMed=15677628;
RX   PubMed=16397213;
RX   PubMed=16541312;
RX   PubMed=17157791;
RX   PubMed=19582160;
RX   PubMed=19593635;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20679594;
RX   PubMed=21778573;
RX   PubMed=22460905;
RX   PubMed=22585861;
RX   PubMed=23151021;
RX   PubMed=23601657;
RX   PubMed=24094812;
RX   PubMed=24176112;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25892236;
RX   PubMed=25960936;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=28287265;
RX   PubMed=28889351;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31978347;
RX   PubMed=35839778;
WW   Info; LINCS; ICBP43; https://lincs.hms.harvard.edu/resources/reagents/icbp43/
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; Pawefish; -; https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/mda-mb-157.htm
WW   Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/breast-cancer-xenograft/mda-mb-157-xenograft-model/
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: ICBP43 breast cancer cell line panel.
CC   Part of: JWGray breast cancer cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Population: African American.
CC   Doubling time: 2.8 days (PubMed=9671407); 66.98 hours (JWGray panel).
CC   HLA typing: A*11:01,68:02; B*15:03,55:02; C*01:02,02:02 (PubMed=25960936).
CC   HLA typing: A*02:01,30:01; B*53:01,53:01; C*04:01,06:02; DQA1*01:02,03:02; DQB1*06:02,06:02; DRB1*11:09,15:01 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (PubMed=15677628; Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Pro42Ser (c.124C>T); ClinVar=VCV000089180; Zygosity=Heterozygous (PubMed=19593635; DepMap=ACH-000621).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Arg644Ser (c.1932G>C); ClinVar=VCV000089233; Zygosity=Heterozygous (PubMed=19593635; DepMap=ACH-000621).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro87fs*53 (c.261_286del26) (p.Ala88Cysfs*52); Zygosity=Homozygous (PubMed=16541312; ATCC=HTB-24; DepMap=ACH-000621).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; PTM; Glycoproteome.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=77.9%; Native American=0%; East Asian, North=4.71%; East Asian, South=0%; South Asian=0%; European, North=1.3%; European, South=16.09% (PubMed=30894373).
CC   Misspelling: MDA-MB-15; Cosmic=897421.
CC   Discontinued: BCRJ; 0319; probable.
CC   Discontinued: DepMap; ACH-001120; true.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): AddexBio=C0006020/4986; ATCC=CRL-7721; ATCC=HTB-24; CCRID=1101HUM-PUMC000077; Cosmic-CLP=925338; ECACC=92020422; PubMed=20679594; PubMed=25877200; PubMed=28889351
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 11 (AddexBio=C0006020/4986; ATCC=CRL-7721; CCRID=1101HUM-PUMC000077; Cosmic-CLP=925338; ECACC=92020422; PubMed=20679594; PubMed=25877200; PubMed=28889351)
ST   D13S317: 11,12 (ATCC=HTB-24)
ST   D16S539: 11
ST   D18S51: 13,16 (ATCC=CRL-7721; ATCC=HTB-24)
ST   D18S51: 16 (CCRID=1101HUM-PUMC000077; PubMed=25877200)
ST   D19S433: 13,14.2 (ATCC=CRL-7721; ATCC=HTB-24)
ST   D19S433: 14.2 (CCRID=1101HUM-PUMC000077)
ST   D21S11: 31,31.2
ST   D2S1338: 25
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 12,14
ST   FGA: 22,23 (ATCC=CRL-7721)
ST   FGA: 23 (ATCC=HTB-24; CCRID=1101HUM-PUMC000077; PubMed=25877200)
ST   Penta D: 3.2,9
ST   Penta E: 11
ST   TH01: 7,8
ST   TPOX: 9,11 (AddexBio=C0006020/4986; ATCC=CRL-7721; ATCC=HTB-24; ECACC=92020422; PubMed=20679594; PubMed=25877200; PubMed=28889351)
ST   TPOX: 11 (CCRID=1101HUM-PUMC000077; Cosmic-CLP=925338)
ST   vWA: 15
DI   NCIt; C4872; Breast carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   44Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 48
//
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RA   Leibovitz, Albert
RT   "Cell lines from human breast.";
RL   (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.161-184; Academic Press; New York; USA (1994).
//
RX   PubMed=730202; DOI=10.1007/BF02616120;
RA   Cailleau, Relda Marie
RA   Olive, Matilde
RA   Cruciger, Quita V.J.
RT   "Long-term human breast carcinoma cell lines of metastatic origin:
RT   preliminary characterization.";
RL   In Vitro 14:911-915(1978).
//
RX   PubMed=833871; DOI=10.1093/jnci/58.2.209;
RA   Fogh, Jorgen
RA   Wright, William C.
RA   Loveless, James D.
RT   "Absence of HeLa cell contamination in 169 cell lines derived from
RT   human tumors.";
RL   J. Natl. Cancer Inst. 58:209-214(1977).
//
RX   PubMed=1961733; DOI=10.1073/pnas.88.23.10657; PMCID=PMC52989;
RA   Runnebaum, Ingo Bernard
RA   Nagarajan, Mahalakshmi
RA   Bowman, Marianne
RA   Soto, Darya
RA   Sukumar, Saraswati
RT   "Mutations in p53 as potential molecular markers for human breast
RT   cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:10657-10661(1991).
//
RX   PubMed=3518877; DOI=10.3109/07357908609038260;
RA   Fogh, Jorgen
RT   "Human tumor lines for cancer research.";
RL   Cancer Invest. 4:157-184(1986).
//
RX   PubMed=4412247; DOI=10.1093/jnci/53.3.661; PMCID=PMC7364228;
RA   Cailleau, Relda Marie
RA   Young, Robert
RA   Olive, Matilde
RA   Reeves, William J. Jr.
RT   "Breast tumor cell lines from pleural effusions.";
RL   J. Natl. Cancer Inst. 53:661-674(1974).
//
RX   PubMed=4471183; DOI=10.1007/BF02616069;
RA   Young, Russell K.
RA   Cailleau, Relda Marie
RA   Mackay, Bruce
RA   Reeves, William J. Jr.
RT   "Establishment of epithelial cell line MDA-MB-157 from metastatic
RT   pleural effusion of human breast carcinoma.";
RL   In Vitro 9:239-245(1974).
//
RX   PubMed=9671407; DOI=10.1038/sj.onc.1201814;
RA   Sweeney, Kimberley J.
RA   Swarbrick, Alexander
RA   Sutherland, Robert Lyndsay
RA   Musgrove, Elizabeth A.
RT   "Lack of relationship between CDK activity and G1 cyclin expression in
RT   breast cancer cells.";
RL   Oncogene 16:2865-2878(1998).
//
RX   PubMed=10862037; DOI=10.1002/1098-2264(200007)28:3<308::AID-GCC9>3.0.CO;2-B;
RA   Kytola, Soili
RA   Rummukainen, Jaana
RA   Nordgren, Ann
RA   Karhu, Ritva
RA   Farnebo, Filip
RA   Isola, Jorma J.
RA   Larsson, Catharina
RT   "Chromosomal alterations in 15 breast cancer cell lines by comparative
RT   genomic hybridization and spectral karyotyping.";
RL   Genes Chromosomes Cancer 28:308-317(2000).
//
RX   PubMed=10969801;
RA   Forozan, Farahnaz
RA   Mahlamaki, Eija H.
RA   Monni, Outi
RA   Chen, Yi-Dong
RA   Veldman, Robin
RA   Jiang, Yuan
RA   Gooden, Gerald C.
RA   Ethier, Stephen P.
RA   Kallioniemi, Anne H.
RA   Kallioniemi, Olli-Pekka
RT   "Comparative genomic hybridization analysis of 38 breast cancer cell
RT   lines: a basis for interpreting complementary DNA microarray data.";
RL   Cancer Res. 60:4519-4525(2000).
//
RX   PubMed=11044355; DOI=10.1054/bjoc.2000.1458; PMCID=PMC2408781;
RA   Davidson, Jeffrey M.
RA   Gorringe, Kylie Louise
RA   Chin, Suet-Feung
RA   Orsetti, Beatrice
RA   Besret, C.
RA   Courtay-Cahen, Celine
RA   Roberts, Ian
RA   Theillet, Charles
RA   Caldas, Carlos
RA   Edwards, Paul A.W.
RT   "Molecular cytogenetic analysis of breast cancer cell lines.";
RL   Br. J. Cancer 83:1309-1317(2000).
//
RX   PubMed=11343771; DOI=10.1016/S0165-4608(00)00387-3;
RA   Rummukainen, Jaana
RA   Kytola, Soili
RA   Karhu, Ritva
RA   Farnebo, Filip
RA   Larsson, Catharina
RA   Isola, Jorma J.
RT   "Aberrations of chromosome 8 in 16 breast cancer cell lines by
RT   comparative genomic hybridization, fluorescence in situ
RT   hybridization, and spectral karyotyping.";
RL   Cancer Genet. Cytogenet. 126:1-7(2001).
//
RX   PubMed=12353263; DOI=10.1002/gcc.10107;
RA   Popovici, Cornel
RA   Basset, Celine
RA   Bertucci, Francois
RA   Orsetti, Beatrice
RA   Adelaide, Jose
RA   Mozziconacci, Marie-Joelle
RA   Conte, Nathalie
RA   Murati, Anne
RA   Ginestier, Christophe
RA   Charafe-Jauffret, Emmanuelle
RA   Ethier, Stephen P.
RA   Lafage-Pochitaloff, Marina
RA   Theillet, Charles
RA   Birnbaum, Daniel
RA   Chaffanet, Max
RT   "Reciprocal translocations in breast tumor cell lines: cloning of a
RT   t(3;20) that targets the FHIT gene.";
RL   Genes Chromosomes Cancer 35:204-218(2002).
//
RX   PubMed=12800145; DOI=10.1002/gcc.10218;
RA   Adelaide, Jose
RA   Huang, Huai-En
RA   Murati, Anne
RA   Alsop, Amber E.
RA   Orsetti, Beatrice
RA   Mozziconacci, Marie-Joelle
RA   Popovici, Cornel
RA   Ginestier, Christophe
RA   Letessier, Anne
RA   Basset, Celine
RA   Courtay-Cahen, Celine
RA   Jacquemier, Jocelyne
RA   Theillet, Charles
RA   Birnbaum, Daniel
RA   Edwards, Paul A.W.
RA   Chaffanet, Max
RT   "A recurrent chromosome translocation breakpoint in breast and
RT   pancreatic cancer cell lines targets the neuregulin/NRG1 gene.";
RL   Genes Chromosomes Cancer 37:333-345(2003).
//
RX   PubMed=15153330; DOI=10.1593/neo.3292; PMCID=PMC1502105;
RA   Watts, George S.
RA   Oshiro, Marc M.
RA   Junk, Damian J.
RA   Wozniak, Ryan J.
RA   Watterson, Summer J.
RA   Domann, Frederick E.
RA   Futscher, Bernard W.
RT   "The acetyltransferase p300/CBP-associated factor is a p53 target gene
RT   in breast tumor cells.";
RL   Neoplasia 6:187-194(2004).
//
RX   PubMed=15677628; DOI=10.1093/carcin/bgi032;
RA   Gorringe, Kylie Louise
RA   Chin, Suet-Feung
RA   Pharoah, Paul D.P.
RA   Staines, Joanne M.
RA   Oliveira, Carla
RA   Edwards, Paul A.W.
RA   Caldas, Carlos
RT   "Evidence that both genetic instability and selection contribute to
RT   the accumulation of chromosome alterations in cancer.";
RL   Carcinogenesis 26:923-930(2005).
//
RX   PubMed=16397213; DOI=10.1158/0008-5472.CAN-05-2853;
RA   Elstrodt, Fons
RA   Hollestelle, Antoinette
RA   Nagel, Jord H.A.
RA   Gorin, Michael
RA   Wasielewski, Marijke
RA   van den Ouweland, Ans M.W.
RA   Merajver, Sofia Diana
RA   Ethier, Stephen P.
RA   Schutte, Mieke
RT   "BRCA1 mutation analysis of 41 human breast cancer cell lines reveals
RT   three new deleterious mutants.";
RL   Cancer Res. 66:41-45(2006).
//
RX   PubMed=16541312; DOI=10.1007/s10549-006-9186-z;
RA   Wasielewski, Marijke
RA   Elstrodt, Fons
RA   Klijn, Jan G.M.
RA   Berns, Els M.J.J.
RA   Schutte, Mieke
RT   "Thirteen new p53 gene mutants identified among 41 human breast cancer
RT   cell lines.";
RL   Breast Cancer Res. Treat. 99:97-101(2006).
//
RX   PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521;
RA   Neve, Richard M.
RA   Chin, Koei
RA   Fridlyand, Jane
RA   Yeh, Jennifer
RA   Baehner, Frederick L.
RA   Fevr, Tea
RA   Clark, Laura
RA   Bayani, Nora
RA   Coppe, Jean-Philippe
RA   Tong, Frances
RA   Speed, Terry
RA   Spellman, Paul T.
RA   DeVries, Sandy
RA   Lapuk, Anna
RA   Wang, Nick J.
RA   Kuo, Wen-Lin
RA   Stilwell, Jackie L.
RA   Pinkel, Daniel
RA   Albertson, Donna G.
RA   Waldman, Frederic M.
RA   McCormick, Frank
RA   Dickson, Robert Brent
RA   Johnson, Michael D.
RA   Lippman, Marc E.
RA   Ethier, Stephen P.
RA   Gazdar, Adi F.
RA   Gray, Joe W.
RT   "A collection of breast cancer cell lines for the study of
RT   functionally distinct cancer subtypes.";
RL   Cancer Cell 10:515-527(2006).
//
RX   PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084;
RA   Kao, Jessica
RA   Salari, Keyan
RA   Bocanegra, Melanie
RA   Choi, Yoon-La
RA   Girard, Luc
RA   Gandhi, Jeet
RA   Kwei, Kevin A.
RA   Hernandez-Boussard, Tina
RA   Wang, Pei
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Pollack, Jonathan R.
RT   "Molecular profiling of breast cancer cell lines defines relevant
RT   tumor models and provides a resource for cancer gene discovery.";
RL   PLoS ONE 4:e6146.1-e6146.16(2009).
//
RX   PubMed=19593635; DOI=10.1007/s10549-009-0460-8;
RA   Hollestelle, Antoinette
RA   Nagel, Jord H.A.
RA   Smid, Marcel
RA   Lam, Suzanne
RA   Elstrodt, Fons
RA   Wasielewski, Marijke
RA   Ng, Ser Sue
RA   French, Pim J.
RA   Peeters, Justine K.
RA   Rozendaal, Marieke J.
RA   Riaz, Muhammad
RA   Koopman, Daphne G.
RA   ten Hagen, Timo L.M.
RA   de Leeuw, Bertie H.C.G.M.
RA   Zwarthoff, Ellen C.
RA   Teunisse, Amina F.A.S.
RA   van der Spek, Peter J.
RA   Klijn, Jan G.M.
RA   Dinjens, Winand N.M.
RA   Ethier, Stephen P.
RA   Clevers, Hans Cornelius
RA   Jochemsen, Aart G.
RA   den Bakker, Michael A.
RA   Foekens, John A.
RA   Martens, John W.M.
RA   Schutte, Mieke
RT   "Distinct gene mutation profiles among luminal-type and basal-type
RT   breast cancer cell lines.";
RL   Breast Cancer Res. Treat. 121:53-64(2010).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474;
RA   Gazdar, Adi F.
RA   Girard, Luc
RA   Lockwood, William W.
RA   Lam, Wan L.
RA   Minna, John D.
RT   "Lung cancer cell lines as tools for biomedical discovery and
RT   research.";
RL   J. Natl. Cancer Inst. 102:1310-1321(2010).
//
RX   PubMed=21778573; DOI=10.3233/BD-2010-0307; PMCID=PMC3532890;
RA   Chavez, Kathryn J.
RA   Garimella, Sireesha V.
RA   Lipkowitz, Stanley
RT   "Triple negative breast cancer cell lines: one tool in the search for
RT   better treatment of triple negative breast cancer.";
RL   Breast Dis. 32:35-48(2010).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura E.
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396;
RA   Marcotte, Richard
RA   Brown, Kevin R.
RA   Suarez Saiz, Fernando Jose
RA   Sayad, Azin
RA   Karamboulas, Konstantina
RA   Krzyzanowski, Paul M.
RA   Sircoulomb, Fabrice
RA   Medrano, Mauricio
RA   Fedyshyn, Yaroslav
RA   Koh, Judice Lie-Yong
RA   van Dyk, Dewald
RA   Fedyshyn, Bohdana
RA   Luhova, Marianna
RA   Brito, Glauber C.
RA   Vizeacoumar, Franco J.
RA   Vizeacoumar, Frederick S.
RA   Datti, Alessandro
RA   Kasimer, Dahlia
RA   Buzina, Alla
RA   Mero, Patricia
RA   Misquitta, Christine
RA   Normand, Josee
RA   Haider, Maliha
RA   Ketela, Troy
RA   Wrana, Jeffrey L.
RA   Rottapel, Robert
RA   Neel, Benjamin G.
RA   Moffat, Jason
RT   "Essential gene profiles in breast, pancreatic, and ovarian cancer
RT   cells.";
RL   Cancer Discov. 2:172-189(2012).
//
RX   PubMed=23151021; DOI=10.1186/1471-2164-13-619; PMCID=PMC3546428;
RA   Grigoriadis, Anita
RA   Mackay, Alan
RA   Noel, Elodie
RA   Wu, Pei-Jun
RA   Natrajan, Rachael
RA   Frankum, Jessica
RA   Reis-Filho, Jorge Sergio
RA   Tutt, Andrew
RT   "Molecular characterisation of cell line models for triple-negative
RT   breast cancers.";
RL   BMC Genomics 13:619.1-619.14(2012).
//
RX   PubMed=23601657; DOI=10.1186/bcr3415; PMCID=PMC3672661;
RA   Riaz, Muhammad
RA   van Jaarsveld, Marijn T.M.
RA   Hollestelle, Antoinette
RA   Prager-van der Smissen, Wendy J.C.
RA   Heine, Anouk A.J.
RA   Boersma, Antonius W.M.
RA   Liu, Jing-Jing
RA   Helmijr, Jean C.A.
RA   Ozturk, Bahar
RA   Smid, Marcel
RA   Wiemer, Erik A.C.
RA   Foekens, John A.
RA   Martens, John W.M.
RT   "miRNA expression profiling of 51 human breast cancer cell lines
RT   reveals subtype and driver mutation-specific miRNAs.";
RL   Breast Cancer Res. 15:R33.1-R33.17(2013).
//
RX   PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310;
RA   Timmerman, Luika A.
RA   Holton, Thomas
RA   Yuneva, Mariia
RA   Louie, Raymond J.
RA   Padro, Merce
RA   Daemen, Anneleen
RA   Hu, Min
RA   Chan, Denise A.
RA   Ethier, Stephen P.
RA   van 't Veer, Laura J.
RA   Polyak, Kornelia
RA   McCormick, Frank
RA   Gray, Joe W.
RT   "Glutamine sensitivity analysis identifies the xCT antiporter as a
RT   common triple-negative breast tumor therapeutic target.";
RL   Cancer Cell 24:450-465(2013).
//
RX   PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590;
RA   Daemen, Anneleen
RA   Griffith, Obi L.
RA   Heiser, Laura M.
RA   Wang, Nicholas J.
RA   Enache, Oana M.
RA   Sanborn, Zachary
RA   Pepin, Francois
RA   Durinck, Steffen
RA   Korkola, James E.
RA   Griffith, Malachi
RA   Hur, Joe S.
RA   Huh, Nam
RA   Chung, Jongsuk
RA   Cope, Leslie
RA   Fackler, Mary Jo
RA   Umbricht, Christopher Benedict
RA   Sukumar, Saraswati
RA   Seth, Pankaj
RA   Sukhatme, Vikas P.
RA   Jakkula, Lakshmi R.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Cho, Raymond J.
RA   Collisson, Eric A.
RA   van 't Veer, Laura J.
RA   Spellman, Paul T.
RA   Gray, Joe W.
RT   "Modeling precision treatment of breast cancer.";
RL   Genome Biol. 14:R110.1-R110.14(2013).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=25892236; DOI=10.1016/j.celrep.2015.03.050; PMCID=PMC4425736;
RA   Lawrence, Robert T.
RA   Perez, Elizabeth M.
RA   Hernandez, Daniel
RA   Miller, Chris P.
RA   Haas, Kelsey M.
RA   Irie, Hanna Y.
RA   Lee, Su-In
RA   Blau, C. Anthony
RA   Villen, Judit
RT   "The proteomic landscape of triple-negative breast cancer.";
RL   Cell Rep. 11:630-644(2015).
//
RX   PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981;
RA   Boegel, Sebastian
RA   Lower, Martin
RA   Bukur, Thomas
RA   Sahin, Ugur
RA   Castle, John C.
RT   "A catalog of HLA type, HLA expression, and neo-epitope candidates in
RT   human cancer cell lines.";
RL   OncoImmunology 3:e954893.1-e954893.12(2014).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, A. Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=28287265; DOI=10.1021/acs.jproteome.6b00470; PMCID=PMC5557415;
RA   Yen, Ten-Yang
RA   Bowen, Spencer
RA   Yen, Roger
RA   Piryatinska, Alexandra
RA   Macher, Bruce A.
RA   Timpe, Leslie C.
RT   "Glycoproteins in claudin-low breast cancer cell lines have a unique
RT   expression profile.";
RL   J. Proteome Res. 16:1391-1400(2017).
//
RX   PubMed=28889351; DOI=10.1007/s10549-017-4496-x;
RA   Saunus, Jodi M.
RA   Smart, Chanel E.
RA   Kutasovic, Jamie R.
RA   Johnston, Rebecca L.
RA   Kalita-de Croft, Priyakshi
RA   Miranda, Mariska
RA   Rozali, Esdy N.
RA   Vargas, Ana Cristina
RA   Reid, Lynne E.
RA   Lorsy, Eva
RA   Cocciardi, Sibylle
RA   Seidens, Tatjana
RA   McCart Reed, Amy Ellen
RA   Dalley, Andrew J.
RA   Wockner, Leesa F.
RA   Johnson, Julie
RA   Sarkar, Debina
RA   Askarian-Amiri, Marjan E.
RA   Simpson, Peter T.
RA   Khanna, Kum Kum
RA   Chenevix-Trench, Georgia
RA   Al-Ejeh, Fares
RA   Lakhani, Sunil R.
RT   "Multidimensional phenotyping of breast cancer cell lines to guide
RT   preclinical research.";
RL   Breast Cancer Res. Treat. 167:289-301(2018).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254;
RA   Nusinow, David Paul
RA   Szpyt, John
RA   Ghandi, Mahmoud
RA   Rose, Christopher M.
RA   McDonald, E. Robert 3rd
RA   Kalocsay, Marian
RA   Jane-Valbuena, Judit
RA   Gelfand, Ellen T.
RA   Schweppe, Devin K.
RA   Jedrychowski, Mark P.
RA   Golji, Javad
RA   Porter, Dale A.
RA   Rejtar, Tomas
RA   Wang, Y. Karen
RA   Kryukov, Gregory V.
RA   Stegmeier, Frank
RA   Erickson, Brian K.
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RA   Gygi, Steven P.
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//