ID Calu-3 AC CVCL_0609 SY CaLu-3; CALU-3; Calu 3; Calu3; CALU3 DR BTO; BTO_0002750 DR CLO; CLO_0002192 DR EFO; EFO_0002819 DR CLDB; cl634 DR CLDB; cl635 DR CLDB; cl5176 DR Abcam; ab275465 DR AddexBio; C0016001/30 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ATCC; HTB-55 DR BCRJ; 0264 DR BioGRID_ORCS_Cell_line; 1375 DR BioSample; SAMN03471552 DR BioSample; SAMN10988517 DR cancercelllines; CVCL_0609 DR CancerTools; 161906 DR CCRID; 1101HUM-PUMC000032 DR CCRID; 1101HUM-PUMC000329 DR CCRID; 3101HUMTCHu157 DR CCRID; 4201HUM-CCTCC00647 DR Cell_Model_Passport; SIDM00922 DR ChEMBL-Cells; CHEMBL3307390 DR ChEMBL-Targets; CHEMBL614534 DR CLS; 305032 DR Cosmic; 687777 DR Cosmic; 910562 DR Cosmic; 933578 DR Cosmic; 945227 DR Cosmic; 961842 DR Cosmic; 1006532 DR Cosmic; 1028940 DR Cosmic; 1146873 DR Cosmic; 1219068 DR Cosmic; 1239869 DR Cosmic; 1434969 DR Cosmic; 1802295 DR Cosmic; 2125219 DR Cosmic; 2664117 DR Cosmic; 2772161 DR Cosmic-CLP; 687777 DR DepMap; ACH-000392 DR EGA; EGAS00001000610 DR EGA; EGAS00001002554 DR GDSC; 687777 DR GEO; GSM108803 DR GEO; GSM108804 DR GEO; GSM159355 DR GEO; GSM159356 DR GEO; GSM159357 DR GEO; GSM159358 DR GEO; GSM253347 DR GEO; GSM353233 DR GEO; GSM434276 DR GEO; GSM513948 DR GEO; GSM514318 DR GEO; GSM784249 DR GEO; GSM794262 DR GEO; GSM817064 DR GEO; GSM827549 DR GEO; GSM886915 DR GEO; GSM887981 DR GEO; GSM1374433 DR GEO; GSM1374434 DR GEO; GSM1669658 DR IARC_TP53; 21264 DR IGRhCellID; Calu3 DR IZSLER; BS TCL 103 DR KCB; KCB 202003YJ DR KCLB; 30055 DR LiGeA; CCLE_462 DR LINCS_HMS; 50010 DR LINCS_LDP; LCL-1631 DR Lonza; 342 DR MetaboLights; MTBLS762 DR MetaboLights; MTBLS2352 DR MetaboLights; MTBLS2840 DR Millipore; SCC438 DR PharmacoDB; Calu3_179_2019 DR PRIDE; PRD000594 DR PRIDE; PXD000589 DR PRIDE; PXD019645 DR PRIDE; PXD023418 DR PRIDE; PXD023422 DR PRIDE; PXD023760 DR PRIDE; PXD024242 DR PRIDE; PXD024375 DR PRIDE; PXD024883 DR PRIDE; PXD025499 DR PRIDE; PXD026302 DR PRIDE; PXD030304 DR PRIDE; PXD034135 DR Progenetix; CVCL_0609 DR PubChem_Cell_line; CVCL_0609 DR TOKU-E; 768 DR Wikidata; Q52392355 RX PubMed=327080; RX PubMed=3129183; RX PubMed=3335022; RX PubMed=3518877; RX PubMed=3940644; RX PubMed=6220172; RX PubMed=7459858; RX PubMed=7515578; RX PubMed=9636188; RX PubMed=10523844; RX PubMed=11064206; RX PubMed=15463957; RX PubMed=17483357; RX PubMed=18083107; RX PubMed=19153074; RX PubMed=19472407; RX PubMed=20090954; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=20557307; RX PubMed=22460905; RX PubMed=22961666; RX PubMed=24207061; RX PubMed=25485619; RX PubMed=25555374; RX PubMed=25877200; RX PubMed=25894527; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=29681454; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=34339474; RX PubMed=35839778; RX PubMed=35879413; WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-604.html WW Info; Wikipedia; -; https://en.wikipedia.org/wiki/Calu-3 WW Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/lung-cancer-xenograft/calu-3-xenograft-model/ WW Provider; MSKCC; -; https://www.mskcc.org/research-advantage/support/technology/tangible-material/calu-3-human-lung-cell-line CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: KuDOS 95 cell line panel. CC Part of: MD Anderson Cell Lines Project. CC From: Memorial Sloan Kettering Cancer Center; New York; USA. CC Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK1980-533. CC Population: Caucasian. CC Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=34339474). CC Doubling time: 35 hours (Note=In RPMI 1640 + 10% FBS), 45 hours (Note=In ACL-3), 37 hours (Note=In ACL-3 + BSA) (PubMed=3940644); 40.1 hours (PubMed=29681454); ~84 hours (PubMed=34339474). CC HLA typing: A*24:02,68:01; B*07:02,51:01; C*15:02,15:02 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Homozygous (PubMed=20557307; ATCC=HTB-55). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Proteomics; Subcellular; Cell surface. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.63%; Native American=0%; East Asian, North=2.09%; East Asian, South=0%; South Asian=0%; European, North=67.76%; European, South=29.51% (PubMed=30894373). CC Misspelling: CALV3; Cosmic=1434969. CC Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. ST Source(s): AddexBio=C0016001/30; ATCC=HTB-55; CCRID; Cosmic-CLP=687777; KCLB=30055; Millipore=SCC438; PubMed=25877200 ST Amelogenin: X ST CSF1PO: 11,12 ST D13S317: 12 ST D16S539: 12,14 ST D18S51: 14,17 ST D19S433: 12,13 ST D21S11: 28,30 ST D2S1338: 19 ST D3S1358: 15,18 ST D5S818: 11 ST D7S820: 10,11 ST D8S1179: 11,15 ST FGA: 25 ST Penta D: 9,16 ST Penta E: 5,21 ST TH01: 6,9.3 ST TPOX: 8 ST vWA: 16,17 DI NCIt; C3512; Lung adenocarcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 25Y CA Cancer cell line DT Created: 04-04-12; Last updated: 27-11-25; Version: 49 CH CVCL_B0ZC ! Abcam Calu-3 TMPRSS2 KO CH CVCL_YZ47 ! Calu-3 2B4 CH CVCL_EQ19 ! Calu3-GemR // RX PubMed=6220172; RA Dracopoli, Nicholas C. RA Fogh, Jorgen RT "Polymorphic enzyme analysis of cultured human tumor cell lines."; RL J. Natl. Cancer Inst. 70:469-476(1983). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347; RA Bausch-Fluck, Damaris RA Hofmann, Andreas RA Bock, Thomas RA Frei, Andreas P. RA Cerciello, Ferdinando RA Jacobs, Andrea RA Moest, Hansjoerg RA Omasits, Ulrich RA Gundry, Rebekah L. RA Yoon, Charles RA Schiess, Ralph RA Schmidt, Alexander RA Mirkowska, Paulina RA Hartlova, Anetta Svitorka RA Van Eyk, Jennifer Eileen RA Bourquin, Jean-Pierre RA Aebersold, Ruedi RA Boheler, Kenneth R. RA Zandstra, Peter W. RA Wollscheid, Bernd RT "A mass spectrometric-derived cell surface protein atlas."; RL PLoS ONE 10:e0121314.1-e0121314.22(2015). // RX PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040; RA Gruenert, Dieter C. RA Willems, Marjolaine RA Cassiman, Jean-Jacques RA Frizzell, Raymond A. RT "Established cell lines used in cystic fibrosis research."; RL J. Cyst. Fibros. 3:191-196(2004). // RX PubMed=35879413; DOI=10.1038/s41588-022-01110-2; RA Rebendenne, Antoine RA Roy, Priyanka RA Bonaventure, Boris RA Chaves Valadao, Ana Luiza RA Desmarets, Lowiese M.B. RA Arnaud-Arnould, Mary RA Rouille, Yves RA Tauziet, Marine RA Giovannini, Donatella RA Touhami, Jawida RA Lee, Yenarae RA DeWeirdt, Peter RA Hegde, Mudra RA Urbach, Serge RA El Koulali, Khadija RA de Gracia, Francisco Garcia RA McKellar, Joe RA Dubuisson, Jean RA Wencker, Melanie RA Belouzard, Sandrine RA Moncorge, Olivier RA Doench, John G. RA Goujon, Caroline RT "Bidirectional genome-wide CRISPR screens reveal host factors RT regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs."; RL Nat. Genet. 54:1090-1102(2022). // RX PubMed=25555374; DOI=10.1016/j.ejps.2014.12.017; RA Kreft, Mateja Erdani RA Dragin Jerman, Urska RA Lasic, Eva RA Hevir-Kene, Neli RA Lanisnik Rizner, Tea RA Peternel, Luka RA Kristan, Katja RT "The characterization of the human cell line Calu-3 under different RT culture conditions and its use as an optimized in vitro model to RT investigate bronchial epithelial function."; RL Eur. J. Pharm. 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RA Riese, Peggy RA Eschke, Kathrin RA Kim, Yeonsu RA Safranko, Zeljka Macak RA Kurolt, Ivan-Christian RA Markotic, Alemka RA Cicin-Sain, Luka RA Steenpass, Laura RT "Identification of cell lines CL-14, CL-40 and CAL-51 as suitable RT models for SARS-CoV-2 infection studies."; RL PLoS ONE 16:e0255622.1-e0255622.15(2021). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=10523844; DOI=10.1038/sj.onc.1202957; RA Agochiya, Mahima RA Brunton, Valerie G. RA Owens, Dewi W. RA Parkinson, Eric Kenneth RA Paraskeva, Christos RA Keith, William Nicol RA Frame, Margaret Catherine RT "Increased dosage and amplification of the focal adhesion kinase gene RT in human cancer cells."; RL Oncogene 18:5646-5653(1999). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=24207061; DOI=10.1186/1559-0275-10-16; PMCID=PMC3827840; RA Cerciello, Ferdinando RA Choi, Meena RA Nicastri, Annalisa RA Bausch-Fluck, Damaris RA Ziegler, Annemarie RA Vitek, Olga RA Felley-Bosco, Emanuela RA Stahel, Rolf A. RA Aebersold, Ruedi RA Wollscheid, Bernd RT "Identification of a seven glycopeptide signature for malignant RT pleural mesothelioma in human serum by selected reaction monitoring."; RL Clin. Proteomics 10:16.1-16.12(2013). // RX PubMed=9636188; DOI=10.1073/pnas.95.13.7556; PMCID=PMC22681; RA Kaplan, Daniel Harry RA Shankaran, Vijay RA Dighe, Anand Shrikant RA Stockert, Elisabeth RA Aguet, Michel RA Old, Lloyd John RA Schreiber, Robert David RT "Demonstration of an interferon gamma-dependent tumor surveillance RT system in immunocompetent mice."; RL Proc. Natl. Acad. Sci. U.S.A. 95:7556-7561(1998). // RX PubMed=7515578; DOI=10.1152/ajplung.1994.266.5.L493; RA Shen, Ben-Quan RA Finkbeiner, Walter E. RA Wine, Jeffrey J. RA Mrsny, Randall Jay RA Widdicombe, Jonathan H. RT "Calu-3: a human airway epithelial cell line that shows cAMP-dependent RT Cl-secretion."; RL Am. J. Physiol. 266:L493-L501(1994). // RX PubMed=18083107; DOI=10.1016/j.cell.2007.11.025; RA Rikova, Klarisa RA Guo, Ai-Lan RA Zeng, Qing-Fu RA Possemato, Anthony RA Yu, Jian RA Haack, Herbert RA Nardone, Julie RA Lee, Kimberly RA Reeves, Cynthia RA Li, Yu RA Hu, Ye-Rong RA Tan, Zhi-Ping RA Stokes, Matthew P. RA Sullivan, Laura RA Mitchell, Jeffrey RA Wetzel, Randy RA MacNeill, Joan RA Ren, Jian-Min RA Yuan, Jin RA Bakalarski, Corey E. RA Villen, Judit RA Kornhauser, Jon M. RA Smith, Bradley RA Li, Dai-Qiang RA Zhou, Xin-Min RA Gygi, Steven P. RA Gu, Ting-Lei RA Polakiewicz, Roberto D. RA Rush, John RA Comb, Michael J. RT "Global survey of phosphotyrosine signaling identifies oncogenic RT kinases in lung cancer."; RL Cell 131:1190-1203(2007). // RX PubMed=19153074; DOI=10.1093/hmg/ddp034; RA Medina, Pedro P. RA Castillo, Sandra D. RA Blanco, Sandra RA Sanz-Garcia, Marta RA Largo, Cristina RA Alvarez, Sara RA Yokota, Jun RA Gonzalez-Neira, Ana RA Benitez, Javier RA Clevers, Hans Cornelius RA Cigudosa, Juan Cruz RA Lazo, Pedro Alfonso RA Sanchez-Cespedes, Montse RT "The SRY-HMG box gene, SOX4, is a target of gene amplification at RT chromosome 6p in lung cancer."; RL Hum. Mol. Genet. 18:1343-1352(2009). // RX PubMed=7459858; RA Rousset, Monique RA Zweibaum, Alain RA Fogh, Jorgen RT "Presence of glycogen and growth-related variations in 58 cultured RT human tumor cell lines of various tissue origins."; RL Cancer Res. 41:1165-1170(1981). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=29681454; DOI=10.1016/j.cell.2018.03.028; PMCID=PMC5935540; RA McMillan, Elizabeth A. RA Ryu, Myung-Jeom RA Diep, Caroline H. RA Mendiratta, Saurabh RA Clemenceau, Jean Rene RA Vaden, Rachel M. RA Kim, Ju-Hwa RA Motoyaji, Takashi RA Covington, Kyle R. RA Peyton, Michael RA Huffman, Kenneth RA Wu, Xiao-Feng RA Girard, Luc RA Sung, Yeojin RA Chen, Pei-Hsaun RA Mallipeddi, Prema Latha RA Lee, Joo Young RA Hanson, Jordan RA Voruganti, Sukesh RA Yu, Yunku RA Park, Sunho RA Sudderth, Jessica RA DeSevo, Christopher RA Muzny, Donna M. RA Doddapaneni, HarshaVardhan RA Gazdar, Adi F. RA Gibbs, Richard Alexander RA Hwang, Tae Hyun RA Heymach, John Victor RA Wistuba, Ignacio Ivan RA Coombes, Kevin Robert RA Williams, Noelle S. RA Wheeler, David A. RA MacMillan, John B. RA DeBerardinis, Ralph J. RA Roth, Michael G. RA Posner, Bruce Arthur RA Minna, John D. RA Kim, Hyun Seok RA White, Michael A. RT "Chemistry-first approach for nomination of personalized treatment in RT lung cancer."; RL Cell 173:864-878.e29(2018). // RX PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680; RA Iwakawa, Reika RA Kohno, Takashi RA Enari, Masatoshi RA Kiyono, Tohru RA Yokota, Jun RT "Prevalence of human papillomavirus 16/18/33 infection and p53 RT mutation in lung adenocarcinoma."; RL Cancer Sci. 101:1891-1896(2010). // RX PubMed=11064206; DOI=10.1016/S0378-5173(00)00452-X; RA Foster, Kimberly A. RA Avery, Michael L. RA Yazdanian, Mehran RA Audus, Kenneth L. RT "Characterization of the Calu-3 cell line as a tool to screen RT pulmonary drug delivery."; RL Int. J. Pharm. 208:1-11(2000). // RX PubMed=17483357; DOI=10.1158/0008-5472.CAN-06-4495; RA Tooker, Patricia RA Yen, Wan-Ching RA Ng, Shi-Chung RA Negro-Vilar, Andres RA Hermann, Thomas W. RT "Bexarotene (LGD1069, Targretin), a selective retinoid X receptor RT agonist, prevents and reverses gemcitabine resistance in NSCLC cells RT by modulating gene amplification."; RL Cancer Res. 67:4425-4433(2007). // RX PubMed=3518877; DOI=10.3109/07357908609038260; RA Fogh, Jorgen RT "Human tumor lines for cancer research."; RL Cancer Invest. 4:157-184(1986). // RX PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846; RA Blanco, Raquel RA Iwakawa, Reika RA Tang, Mo-Ying RA Kohno, Takashi RA Angulo, Barbara RA Pio, Ruben RA Montuenga, Luis M. RA Minna, John D. RA Yokota, Jun RA Sanchez-Cespedes, Montse RT "A gene-alteration profile of human lung cancer cell lines."; RL Hum. Mutat. 30:1199-1206(2009). // RX PubMed=20090954; DOI=10.1371/journal.pone.0008729; PMCID=PMC2806919; RA Yoshikawa, Tomoki RA Hill, Terence E. RA Yoshikawa, Naoko RA Popov, Vsevolod L. RA Galindo, Cristi L. RA Garner, Harold Ray RA Peters, Clarence James RA Tseng, Chien-Te RT "Dynamic innate immune responses of human bronchial epithelial cells RT to severe acute respiratory syndrome-associated coronavirus RT infection."; RL PLoS ONE 5:e8729.1-e8729.16(2010). // RX PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112; PMCID=PMC3567922; RA Byers, Lauren Averett RA Wang, Jing RA Nilsson, Monique B. RA Fujimoto, Junya RA Saintigny, Pierre RA Yordy, John Stuart RA Giri, Uma RA Peyton, Michael RA Fan, You-Hong RA Diao, Li-Xia RA Masrorpour, Fatemeh RA Shen, Li RA Liu, Wen-Bin RA Duchemann, Boris RA Tumula, Praveen RA Bhardwaj, Vikas RA Welsh, James RA Weber, Stephanie RA Glisson, Bonnie S. RA Kalhor, Neda RA Wistuba, Ignacio Ivan RA Girard, Luc RA Lippman, Scott M. RA Mills, Gordon B. RA Coombes, Kevin Robert RA Weinstein, John N. RA Minna, John D. RA Heymach, John Victor RT "Proteomic profiling identifies dysregulated pathways in small cell RT lung cancer and novel therapeutic targets including PARP1."; RL Cancer Discov. 2:798-811(2012). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=3129183; RA Hubbard, Walter C. RA Alley, Michael Curtis RA McLemore, Theodore L. RA Boyd, Michael R. 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