ID   U266B1
AC   CVCL_0566
SY   U266-B1; U266 B1; U-266; U 266; U266; U266S; U266BL; U266 Bl; 266 Bl
DR   BTO; BTO_0001594
DR   CLO; CLO_0009457
DR   CLO; CLO_0009458
DR   EFO; EFO_0001254
DR   MCCL; MCC:0000471
DR   CLDB; cl4584
DR   CLDB; cl4609
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ArrayExpress; E-MTAB-7721
DR   ArrayExpress; E-MTAB-7722
DR   ArrayExpress; E-TABM-937
DR   ATCC; TIB-196
DR   BCRC; 60437
DR   BCRJ; 0240
DR   BioSample; SAMN01821605
DR   BioSample; SAMN01821669
DR   BioSample; SAMN03472935
DR   BioSample; SAMN10987866
DR   cancercelllines; CVCL_0566
DR   CCRID; 1101HUM-PUMC000684
DR   CCRID; 4201HUM-CCTCC00325
DR   CCTCC; GDC0301
DR   CCTCC; GDC0325
DR   Cell_Model_Passport; SIDM00417
DR   CGH-DB; 37-1
DR   CGH-DB; 9155-4
DR   ChEMBL-Cells; CHEMBL3308535
DR   ChEMBL-Targets; CHEMBL2366315
DR   CLS; 300259
DR   Cosmic; 720795
DR   Cosmic; 742953
DR   Cosmic; 753615
DR   Cosmic; 759903
DR   Cosmic; 759912
DR   Cosmic; 760401
DR   Cosmic; 760647
DR   Cosmic; 886087
DR   Cosmic; 888019
DR   Cosmic; 991555
DR   Cosmic; 1424220
DR   Cosmic; 1483078
DR   Cosmic; 1762463
DR   Cosmic; 1889513
DR   Cosmic; 2081409
DR   Cosmic; 2159571
DR   Cosmic; 2367281
DR   Cosmic; 2391806
DR   Cosmic; 2809754
DR   Cosmic-CLP; 753615
DR   DepMap; ACH-000626
DR   DSMZ; ACC-9
DR   DSMZCellDive; ACC-9
DR   ECACC; 85051003
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   EGA; EGAS00001002554
DR   GDSC; 753615
DR   GEO; GSM143345
DR   GEO; GSM545498
DR   GEO; GSM545499
DR   GEO; GSM562821
DR   GEO; GSM827442
DR   GEO; GSM887721
DR   GEO; GSM888815
DR   GEO; GSM1374970
DR   GEO; GSM1670556
DR   IARC_TP53; 361
DR   IARC_TP53; 30185
DR   IBRC; C10148
DR   IGRhCellID; U266B1
DR   IZSLER; BS TCL 233
DR   KCB; KCB 2013024YJ
DR   LiGeA; CCLE_465
DR   LINCS_LDP; LCL-2050
DR   Lonza; 106
DR   Lonza; 807
DR   NCBI_Iran; C151
DR   PharmacoDB; U266B1_1630_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0566
DR   PubChem_Cell_line; CVCL_0566
DR   Wikidata; Q54973634
RX   CelloPub=CLPUB00604;
RX   DOI=10.1007/0-306-46877-8_4;
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1373872;
RX   PubMed=1643757;
RX   PubMed=1720489;
RX   PubMed=2140233;
RX   PubMed=2537114;
RX   PubMed=2985879;
RX   PubMed=3159941;
RX   PubMed=3874327;
RX   PubMed=4097745;
RX   PubMed=4104421;
RX   PubMed=6350451;
RX   PubMed=8943038;
RX   PubMed=9685479;
RX   PubMed=10087940;
RX   PubMed=10557056;
RX   PubMed=10583232;
RX   PubMed=10936422;
RX   PubMed=11154231;
RX   PubMed=11157491;
RX   PubMed=11429052;
RX   PubMed=14555701;
RX   PubMed=15215163;
RX   PubMed=16956823;
RX   PubMed=17171682;
RX   PubMed=17229644;
RX   PubMed=17692805;
RX   PubMed=18647998;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=21173094;
RX   PubMed=22460905;
RX   PubMed=22806891;
RX   PubMed=23074853;
RX   PubMed=23992230;
RX   PubMed=25485619;
RX   PubMed=25688540;
RX   PubMed=25877200;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=30285677;
RX   PubMed=30545397;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31160637;
RX   PubMed=32123307;
RX   PubMed=35839778;
WW   Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Group: Hybridoma fusion partner cell line.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: LL-100 blood cancer cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
CC   Population: Caucasian.
CC   Characteristics: Produces IgE lambda.
CC   Doubling time: 108-144 hours (PubMed=4104421); ~55 hours (DSMZ=ACC-9).
CC   HLA typing: A*02:01,03; B*07,40; C*03:04,07 (Direct_author_submission).
CC   HLA typing: A*02:01,03:01; B*07:02,40:01; C*03:04,07:02 (PubMed=26589293).
CC   HLA typing: A*02:01:01;03:01:01; B*07:02:01,40:01:02; C*03:04:01,07:02:01; DPA1*01:03:01,01:03:01; DPB1*04:01:01,02:01:02; DQA1*01:02:01,05:01:01; DQB1*02:01:01,06:02:01; DRA*01:02:02,01:02:03; DRB1*03:01:01,15:01:01 (DSMZCellDive=ACC-9).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (Cosmic-CLP=753615; DepMap=ACH-000626).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (Cosmic-CLP=753615; DepMap=ACH-000626).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (PubMed=1373872; PubMed=21173094; Cosmic-CLP=753615; DepMap=ACH-000626).
CC   Sequence variation: Mutation; HGNC; HGNC:12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (PubMed=17692805).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=2.78%; East Asian, South=0.29%; South Asian=0.45%; European, North=80.76%; European, South=15.72% (PubMed=30894373).
CC   Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck, Catherine.
CC   Discontinued: BCRJ; 0240; probable.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: Plasma cell; CL=CL_0000786.
ST   Source(s): ATCC=TIB-196; CCRID; CLS=300259; Cosmic-CLP=753615; DSMZ=ACC-9; ECACC=85051003; PubMed=25877200; Technion Genomics Center
ST   Amelogenin: X,Y
ST   CSF1PO: 12,13
ST   D10S1248: 14
ST   D12S391: 18
ST   D13S317: 12
ST   D16S539: 10
ST   D18S51: 12,14
ST   D19S433: 13,15
ST   D1S1656: 12,15
ST   D21S11: 28,29
ST   D22S1045: 15,16
ST   D2S1338: 20,23
ST   D2S441: 10,11
ST   D3S1358: 17
ST   D5S818: 11,12
ST   D6S1043: 11,17
ST   D7S820: 11,12
ST   D8S1179: 13
ST   DYS391: 10
ST   FGA: 18
ST   Penta D: 10,13
ST   Penta E: 10,12
ST   TH01: 5,7
ST   TPOX: 8
ST   vWA: 17
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_JA36 ! U255
OI   CVCL_W412 ! U268
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 48
//
RX   CelloPub=CLPUB00604;
RA   Chow, Sharon
RT   "Targeted capture and sequencing of immunoglobulin rearrangements
RT   in multiple myeloma to enable detection of minimal residual disease.";
RL   Thesis MSc (2017); University of Toronto; Toronto; Canada.
//
RX   DOI=10.1007/0-306-46877-8_4;
RA   Jernberg-Wiklund, Helena
RA   Nilsson, Kenneth
RT   "Multiple myeloma cell lines.";
RL   (In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=1373872;
RA   Mazars, Georges-Raoul
RA   Portier, Marielle
RA   Zhang, Xue-Guang
RA   Jourdan, Michel
RA   Bataille, Francois-Regis
RA   Theillet, Charles
RA   Klein, Bernard
RT   "Mutations of the p53 gene in human myeloma cell lines.";
RL   Oncogene 7:1015-1018(1992).
//
RX   PubMed=1643757; DOI=10.1016/0090-1229(92)90205-3;
RA   Renz, Harald
RA   Or, Reuven
RA   Domenico, Joanne
RA   Leung, Donald Y.M.
RA   Gelfand, Erwin William
RT   "Reciprocal regulatory effects of IL-4 on cell growth and
RT   immunoglobulin production in Ig-secreting human B-cell lines.";
RL   Clin. Immunol. Immunopathol. 64:233-241(1992).
//
RX   PubMed=1720489; DOI=10.1016/0145-2126(91)90110-f;
RA   Suzuki, Akira
RA   Takahashi, Takayuki
RA   Okuno, Yoshiaki
RA   Fukumoto, Manabu
RA   Fukui, Hiroyasu
RA   Koishihara, Yasuo
RA   Ohsugi, Yoshiaki
RA   Ohno, Yohichiro
RA   Imura, Hiroo
RT   "Estimation of interleukin 6 production by reverse
RT   transcriptase-polymerase chain reaction in four human myeloma cell
RT   lines.";
RL   Leuk. Res. 15:1043-1050(1991).
//
RX   PubMed=2140233; DOI=10.1111/j.1440-1827.1990.tb01549.x;
RA   Nakano, Akinobu
RA   Harada, Takayuki
RA   Morikawa, Shigeru
RA   Kato, Yuzuru
RT   "Expression of leukocyte common antigen (CD45) on various human
RT   leukemia/lymphoma cell lines.";
RL   Acta Pathol. Jpn. 40:107-115(1990).
//
RX   PubMed=2537114; DOI=10.1182/blood.V73.2.566.566;
RA   Duperray, Christophe
RA   Klein, Bernard
RA   Durie, Brian G.M.
RA   Zhang, X.
RA   Jourdan, Michel
RA   Poncelet, Philippe
RA   Favier, Francois
RA   Vincent, Claude
RA   Brochier, Jean
RA   Lenoir, Gilbert Marcel
RA   Bataille, Francois-Regis
RT   "Phenotypic analysis of human myeloma cell lines.";
RL   Blood 73:566-572(1989).
//
RX   PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- 1.
RT   Carboxylic esterase.";
RL   Leuk. Res. 9:209-229(1985).
//
RX   PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- III.
RT   Beta-hexosaminidase (E.C. 3.2.1.30).";
RL   Leuk. Res. 9:549-559(1985).
//
RX   PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid
RT   phosphatase.";
RL   Leuk. Res. 9:537-548(1985).
//
RX   PubMed=4097745; PMCID=PMC1712861;
RA   Nilsson, Kenneth
RA   Bennich, Hans
RA   Johansson, Stig Gunnar Olof
RA   Ponten, Jan
RT   "Established immunoglobulin producing myeloma (IgE) and lymphoblastoid
RT   (IgG) cell lines from an IgE myeloma patient.";
RL   Clin. Exp. Immunol. 7:477-489(1970).
//
RX   PubMed=4104421; DOI=10.1002/ijc.2910070303;
RA   Nilsson, Kenneth
RT   "Characteristics of established myeloma and lymphoblastoid cell lines
RT   derived from an E myeloma patient: a comparative study.";
RL   Int. J. Cancer 7:380-396(1971).
//
RX   PubMed=6350451; DOI=10.4049/jimmunol.131.3.1201;
RA   Abrams, Paul G.
RA   Knost, James A.
RA   Clarke, Gregory
RA   Wilburn, Shannon
RA   Oldham, Robert K.
RA   Foon, Kenneth Alan
RT   "Determination of the optimal human cell lines for development of
RT   human hybridomas.";
RL   J. Immunol. 131:1201-1204(1983).
//
RX   PubMed=8943038; DOI=10.1073/pnas.93.24.13931; PMCID=PMC19472;
RA   Bergsagel, Peter Leif
RA   Chesi, Marta
RA   Nardini, Elena
RA   Brents, Leslie A.
RA   Kirby, Suzanne Lee
RA   Kuehl, Walter Michael
RT   "Promiscuous translocations into immunoglobulin heavy chain switch
RT   regions in multiple myeloma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:13931-13936(1996).
//
RX   PubMed=9685479; DOI=10.1093/nar/26.16.3651; PMCID=PMC147775;
RA   Hultdin, Magnus
RA   Gronlund, Elisabeth
RA   Norrback, Karl-Frederik
RA   Eriksson-Lindstrom, E.
RA   Just, Tom
RA   Roos, Goran
RT   "Telomere analysis by fluorescence in situ hybridization and flow
RT   cytometry.";
RL   Nucleic Acids Res. 26:3651-3656(1998).
//
RX   PubMed=10087940; DOI=10.1016/S0165-4608(98)00157-5;
RA   Kuipers, Jeroen
RA   Vaandrager, Jan Willem
RA   Weghuis, Danielle Olde
RA   Pearson, Peter Lees
RA   Scheres, Jacques
RA   Lokhorst, Henk Martinus
RA   Clevers, Hans Cornelius
RA   Bast, Bert J.E.G.
RT   "Fluorescence in situ hybridization analysis shows the frequent
RT   occurrence of 14q32.3 rearrangements with involvement of
RT   immunoglobulin switch regions in myeloma cell lines.";
RL   Cancer Genet. Cytogenet. 109:99-107(1999).
//
RX   PubMed=10557056; DOI=10.1038/sj.leu.2401563;
RA   Yoshida, S.
RA   Nakazawa, Naozo
RA   Iida, S.
RA   Hayami, Yoshihito
RA   Sato, S.
RA   Wakita, Atsushi
RA   Shimizu, S.
RA   Taniwaki, Masafumi
RA   Ueda, R.
RT   "Detection of MUM1/IRF4-IgH fusion in multiple myeloma.";
RL   Leukemia 13:1812-1816(1999).
//
RX   PubMed=10583232; DOI=10.1046/j.1365-2141.1999.01705.x;
RA   Puthier, Denis
RA   Derenne, Sophie
RA   Barille, Sophie
RA   Moreau, Philippe
RA   Harousseau, Jean-Luc
RA   Bataille, Francois-Regis
RA   Amiot, Martine
RT   "Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells.";
RL   Br. J. Haematol. 107:392-395(1999).
//
RX   PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2;
RA   Drexler, Hans Gunther
RA   Matsuo, Yoshinobu
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   multiple myeloma and plasma cell leukemia.";
RL   Leuk. Res. 24:681-703(2000).
//
RX   PubMed=11154231; DOI=10.1182/blood.V97.2.516;
RA   Hjertner, Oyvind
RA   Hjorth-Hansen, Henrik
RA   Borset, Magne
RA   Seidel, Carina
RA   Waage, Anders
RA   Sundan, Anders
RT   "Bone morphogenetic protein-4 inhibits proliferation and induces
RT   apoptosis of multiple myeloma cells.";
RL   Blood 97:516-522(2001).
//
RX   PubMed=11157491; DOI=10.1182/blood.V97.3.729;
RA   Chesi, Marta
RA   Brents, Leslie A.
RA   Ely, Sarah A.
RA   Bais, Carlos
RA   Robbiani, Davide F.
RA   Mesri, Enrique A.
RA   Kuehl, Walter Michael
RA   Bergsagel, Peter Leif
RT   "Activated fibroblast growth factor receptor 3 is an oncogene that
RT   contributes to tumor progression in multiple myeloma.";
RL   Blood 97:729-736(2001).
//
RX   PubMed=11429052; DOI=10.1111/j.1349-7006.2001.tb01142.x; PMCID=PMC5926752;
RA   Hanamura, Ichiro
RA   Iida, Shinsuke
RA   Akano, Yumiko
RA   Hayami, Yoshihito
RA   Kato, Miyuki
RA   Miura, Kazuhisa
RA   Harada, Shinsuke
RA   Banno, Shogo
RA   Wakita, Atsushi
RA   Kiyoi, Hitoshi
RA   Naoe, Tomoki
RA   Shimizu, Shiro
RA   Sonta, Shin-ichi
RA   Nitta, Masakazu
RA   Taniwaki, Masafumi
RA   Ueda, Ryuzo
RT   "Ectopic expression of MAFB gene in human myeloma cells carrying
RT   (14;20)(q32;q11) chromosomal translocations.";
RL   Jpn. J. Cancer Res. 92:638-644(2001).
//
RX   PubMed=14555701;
RA   Shammas, Masood A.
RA   Shmookler Reis, Robert Joseph
RA   Akiyama, Masaharu
RA   Koley, Hemanta
RA   Chauhan, Dharminder
RA   Hideshima, Teru
RA   Goyal, Raj K.
RA   Hurley, Laurence H.
RA   Anderson, Kenneth Carl
RA   Munshi, Nikhil C.
RT   "Telomerase inhibition and cell growth arrest by G-quadruplex
RT   interactive agent in multiple myeloma.";
RL   Mol. Cancer Ther. 2:825-833(2003).
//
RX   PubMed=15215163; DOI=10.1016/S0002-9440(10)63276-2; PMCID=PMC1618545;
RA   Inoue, Jun
RA   Otsuki, Takemi
RA   Hirasawa, Akira
RA   Imoto, Issei
RA   Matsuo, Yoshinobu
RA   Shimizu, Shiroh
RA   Taniwaki, Masafumi
RA   Inazawa, Johji
RT   "Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be
RT   associated with drug-resistance phenotype in multiple myeloma.";
RL   Am. J. Pathol. 165:71-81(2004).
//
RX   PubMed=16956823;
RA   Bataille, Francois-Regis
RA   Jego, Gaatan
RA   Robillard, Nelly
RA   Barille-Nion, Sophie
RA   Harousseau, Jean-Luc
RA   Moreau, Philippe
RA   Amiot, Martine
RA   Pellat-Deceunynck, Catherine
RT   "The phenotype of normal, reactive and malignant plasma cells.
RT   Identification of 'many and multiple myelomas' and of new targets for
RT   myeloma therapy.";
RL   Haematologica 91:1234-1240(2006).
//
RX   PubMed=17171682; DOI=10.1002/gcc.20404;
RA   Lombardi, Luigia
RA   Poretti, Giulia
RA   Mattioli, Michela
RA   Fabris, Sonia
RA   Agnelli, Luca
RA   Bicciato, Silvio
RA   Kwee, Ivo
RA   Rinaldi, Andrea
RA   Ronchetti, Domenica
RA   Verdelli, Donata
RA   Lambertenghi-Deliliers, Giorgio
RA   Bertoni, Francesco
RA   Neri, Antonino
RT   "Molecular characterization of human multiple myeloma cell lines by
RT   integrative genomics: insights into the biology of the disease.";
RL   Genes Chromosomes Cancer 46:226-238(2007).
//
RX   PubMed=17229644; DOI=10.3324/haematol.10300;
RA   Sanda, Takaomi
RA   Iida, Shinsuke
RA   Kayukawa, Satoshi
RA   Ueda, Ryuzo
RT   "Induction of class II major histocompatibility complex expression in
RT   human multiple myeloma cells by retinoid.";
RL   Haematologica 92:115-120(2007).
//
RX   PubMed=17692805; DOI=10.1016/j.ccr.2007.07.003; PMCID=PMC2083698;
RA   Keats, Jonathan J.
RA   Fonseca, Rafael
RA   Chesi, Marta
RA   Schop, Roelandt
RA   Baker, Angela
RA   Chng, Wee-Joo
RA   Van Wier, Scott
RA   Tiedemann, Rodger
RA   Shi, Chang-Xin
RA   Sebag, Michael
RA   Braggio, Esteban
RA   Henry, Travis
RA   Zhu, Yuan-Xiao
RA   Fogle, Homer
RA   Price-Troska, Tammy L.
RA   Ahmann, Gregory J.
RA   Mancini, Catherine
RA   Brents, Leslie A.
RA   Kumar, Shaji K.
RA   Greipp, Philip Robert
RA   Dispenzieri, Angela
RA   Bryant, Barb
RA   Mulligan, George
RA   Bruhn, Laurakay
RA   Barrett, Michael T.
RA   Valdez, Riccardo
RA   Trent, Jeffrey M.
RA   Stewart, A. Keith
RA   Carpten, John D.
RA   Bergsagel, Peter Leif
RT   "Promiscuous mutations activate the noncanonical NF-kappaB pathway in
RT   multiple myeloma.";
RL   Cancer Cell 12:131-144(2007).
//
RX   PubMed=18647998; DOI=10.1093/jncimonographs/lgn011; PMCID=PMC2737184;
RA   Dib, Amel
RA   Gabrea, Ana
RA   Glebov, Oleg K.
RA   Bergsagel, Peter Leif
RA   Kuehl, Walter Michael
RT   "Characterization of MYC translocations in multiple myeloma cell
RT   lines.";
RL   J. Natl. Cancer Inst. Monogr. 39:25-31(2008).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=21173094; DOI=10.3324/haematol.2010.033456; PMCID=PMC3069235;
RA   Moreaux, Jerome
RA   Klein, Bernard
RA   Bataille, Francois-Regis
RA   Descamps, Geraldine
RA   Maiga, Sophie
RA   Hose, Dirk
RA   Goldschmidt, Hartmut
RA   Jauch, Anna
RA   Reme, Thierry
RA   Jourdan, Michel
RA   Amiot, Martine
RA   Pellat-Deceunynck, Catherine
RT   "A high-risk signature for patients with multiple myeloma established
RT   from the molecular classification of human myeloma cell lines.";
RL   Haematologica 96:574-582(2011).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura E.
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=22806891; DOI=10.1182/blood-2011-08-371567;
RA   Holien, Toril
RA   Vatsveen, Thea Kristin
RA   Hella, Hanne
RA   Waage, Anders
RA   Sundan, Anders
RT   "Addiction to c-MYC in multiple myeloma.";
RL   Blood 120:2450-2453(2012).
//
RX   PubMed=23074853; DOI=10.1134/S1990519X12050136;
RA   Turilova, Victoria I.
RA   Smirnova, Tatyana Dmitriyevna
RT   "Karyotypic variability of human myeloma cell lines.";
RL   Tsitologiia 54:621-636(2012).
//
RX   PubMed=23992230; DOI=10.1111/ejh.12192; PMCID=PMC3834223;
RA   Greenberg, Alexandra J.
RA   Walters, Denise K.
RA   Kumar, Shaji K.
RA   Rajkumar, S. Vincent
RA   Jelinek, Diane F.
RT   "Responsiveness of cytogenetically discrete human myeloma cell lines
RT   to lenalidomide: lack of correlation with cereblon and interferon
RT   regulatory factor 4 expression levels.";
RL   Eur. J. Haematol. 91:504-513(2013).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25688540; DOI=10.1002/cyto.a.22643;
RA   Maiga, Sophie
RA   Brosseau, Carole
RA   Descamps, Geraldine
RA   Dousset, Christelle
RA   Gomez-Bougie, Patricia
RA   Chiron, David
RA   Menoret, Emmanuelle
RA   Kervoelen, Charlotte
RA   Vie, Henri
RA   Cesbron, Anne
RA   Moreau-Aubry, Agnes
RA   Amiot, Martine
RA   Pellat-Deceunynck, Catherine
RT   "A simple flow cytometry-based barcode for routine authentication of
RT   multiple myeloma and mantle cell lymphoma cell lines.";
RL   Cytometry A 87:285-288(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, A. Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786;
RA   Tan, Kar-Tong
RA   Ding, Ling-Wen
RA   Sun, Qiao-Yang
RA   Lao, Zhen-Tang
RA   Chien, Wenwen
RA   Ren, Xi
RA   Xiao, Jin-Fen
RA   Loh, Xin-Yi
RA   Xu, Liang
RA   Lill, Michael
RA   Mayakonda, Anand
RA   Lin, De-Chen
RA   Yang, Henry He
RA   Koeffler, Harold Phillip
RT   "Profiling the B/T cell receptor repertoire of lymphocyte derived cell
RT   lines.";
RL   BMC Cancer 18:940.1-940.13(2018).
//
RX   PubMed=30545397; DOI=10.1186/s13045-018-0679-0; PMCID=PMC6293660;
RA   Tessoulin, Benoit
RA   Moreau-Aubry, Agnes
RA   Descamps, Geraldine
RA   Gomez-Bougie, Patricia
RA   Maiga, Sophie
RA   Gaignard, Alban
RA   Chiron, David
RA   Menoret, Emmanuelle
RA   Le Gouill, Steven
RA   Moreau, Philippe
RA   Amiot, Martine
RA   Pellat-Deceunynck, Catherine
RT   "Whole-exon sequencing of human myeloma cell lines shows mutations
RT   related to myeloma patients at relapse with major hits in the DNA
RT   regulation and repair pathways.";
RL   J. Hematol. Oncol. 11:137.1-137.13(2018).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646;
RA   Quentmeier, Hilmar
RA   Pommerenke, Claudia
RA   Dirks, Wilhelm Gerhard
RA   Eberth, Sonja
RA   Koeppel, Max
RA   MacLeod, Roderick A.F.
RA   Nagel, Stefan
RA   Steube, Klaus G.
RA   Uphoff, Cord C.
RA   Drexler, Hans Gunther
RT   "The LL-100 panel: 100 cell lines for blood cancer studies.";
RL   Sci. Rep. 9:8218.1-8218.14(2019).
//
RX   PubMed=32123307; DOI=10.1038/s41375-020-0785-1; PMCID=PMC7483300;
RA   Sarin, Vishesh
RA   Yu, Katharine
RA   Ferguson, Ian D.
RA   Gugliemini, Olivia
RA   Nix, Matthew A.
RA   Hann, Byron
RA   Sirota, Marina
RA   Wiita, Arun P.
RT   "Evaluating the efficacy of multiple myeloma cell lines as models for
RT   patient tumors via transcriptomic correlation analysis.";
RL   Leukemia 34:2754-2765(2020).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//