ID   TRM-6/PDX-1
AC   CVCL_0562
SY   T6/PDX
DR   MCCL; MCC:0000464
DR   Wikidata; Q54973031
RX   PubMed=10847584;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6107; PDX1.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Fetal pancreas; UBERON=UBERON_0003921.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_G708 ! TRM-6
SX   Sex unspecified
AG   24FW
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 16
//
RX   PubMed=10847584; DOI=10.1210/mend.14.6.0476;
RA   Itkin-Ansari, Pamela
RA   Demeterco-Berggren, Carla
RA   Bossie, Stuart
RA   Gouty, Dominique
RA   Beattie, Gillian M.
RA   Movassat, Jamileh
RA   Mally, Martin I.
RA   Hayek, Alberto
RA   Levine, Fred
RT   "PDX-1 and cell-cell contact act in synergy to promote delta-cell
RT   development in a human pancreatic endocrine precursor cell line.";
RL   Mol. Endocrinol. 14:814-822(2000).
//