ID SU-DHL-4 AC CVCL_0539 SY SUDHL4; Sudhl4; SUDHL-4; Sudhl-4; SuDHL 4; SUD-4; SUD4; SU4; Stanford University-Diffuse Histiocytic Lymphoma-4; DHL-4; DHL4 DR BTO; BTO_0006462 DR CLO; CLO_0037061 DR EFO; EFO_0006492 DR MCCL; MCC:0000440 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ArrayExpress; E-MTAB-7721 DR ArrayExpress; E-MTAB-7722 DR ATCC; CRL-2957 DR BioGRID_ORCS_Cell_line; 742 DR BioSample; SAMN03473232 DR BioSample; SAMN10988472 DR cancercelllines; CVCL_0539 DR CCRID; 3101HUMSCSP5048 DR Cell_Model_Passport; SIDM00405 DR ChEMBL-Cells; CHEMBL3308053 DR ChEMBL-Targets; CHEMBL613711 DR CLS; 305106 DR Cosmic; 850203 DR Cosmic; 932763 DR Cosmic; 999780 DR Cosmic; 1067443 DR Cosmic; 1079254 DR Cosmic; 1517656 DR Cosmic; 1541909 DR Cosmic; 1636687 DR Cosmic; 1714160 DR Cosmic; 1945192 DR Cosmic; 2276338 DR Cosmic; 2361375 DR Cosmic; 2437313 DR Cosmic-CLP; 1331035 DR DepMap; ACH-000365 DR DSMZ; ACC-495 DR DSMZCellDive; ACC-495 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR EGA; EGAS00001002554 DR ENCODE; ENCBS265MKB DR ENCODE; ENCBS980NLV DR GDSC; 1331035 DR GEO; GSM274842 DR GEO; GSM380145 DR GEO; GSM499735 DR GEO; GSM552463 DR GEO; GSM562826 DR GEO; GSM887653 DR GEO; GSM888745 DR GEO; GSM1035322 DR GEO; GSM1374906 DR GEO; GSM1670485 DR IARC_TP53; 25031 DR IARC_TP53; 28236 DR ICLC; HTL10002 DR LiGeA; CCLE_386 DR LINCS_LDP; LCL-1136 DR Lonza; 270 DR PharmacoDB; SUDHL4_1502_2019 DR PRIDE; PXD000589 DR PRIDE; PXD030304 DR Progenetix; CVCL_0539 DR PubChem_Cell_line; CVCL_0539 DR Ubigene; YC-C082 DR Wikidata; Q54970717 RX DOI=10.1016/B978-0-12-221970-2.50457-5; RX DOI=10.11418/jtca1981.15.4_211; RX PubMed=83902; RX PubMed=177185; RX PubMed=214220; RX PubMed=371794; RX PubMed=2875799; RX PubMed=2985879; RX PubMed=3159941; RX PubMed=3874327; RX PubMed=3881165; RX PubMed=8547074; RX PubMed=8957066; RX PubMed=9738977; RX PubMed=9787181; RX PubMed=10739008; RX PubMed=11226526; RX PubMed=12169673; RX PubMed=17363600; RX PubMed=18357372; RX PubMed=19278952; RX PubMed=20054396; RX PubMed=20628145; RX PubMed=20889926; RX PubMed=22460905; RX PubMed=23292937; RX PubMed=25355872; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25894527; RX PubMed=26589293; RX PubMed=26727417; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=28356514; RX PubMed=29416618; RX PubMed=29666304; RX PubMed=30165192; RX PubMed=30285677; RX PubMed=30629668; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31160637; RX PubMed=31978347; RX PubMed=35839778; WW Info; MCLP; -; https://tcpaportal.org/mclp/ CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: LL-100 blood cancer cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Population: Caucasian. CC Doubling time: ~40 hours (DSMZ=ACC-495). CC HLA typing: A*02:01,03:01; B*15:01,15:01; C*03:04,03:04 (PubMed=26589293). CC HLA typing: A*02:01:01,02:01:01; B*15:01:01,15:01:01; C*03:04:01,03:04:01; DPA1*02:01:02,02:01:02; DPB1*01:01:01,01:01:01; DQA1*01:02:01,01:02:01; DQB1*06:02:01,06:02:01; DRA*01:02:03,01:02:03; DRB1*15:01:01,15:01:01 (DSMZCellDive=ACC-495). CC Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526; Sanger). CC Sequence variation: Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL2 (PubMed=2875799). CC Sequence variation: Mutation; HGNC; HGNC:3527; EZH2; Simple; p.Tyr646Ser (c.1937A>C) (Y641S); ClinVar=VCV000376218; Zygosity=Heterozygous (Cosmic-CLP=1331035; DepMap=ACH-000365). CC Sequence variation: Mutation; HGNC; HGNC:3527; EZH2; Simple; p.Tyr666Asn (c.1996T>A) (Y661N); Zygosity=Heterozygous (Cosmic-CLP=1331035; DepMap=ACH-000365). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Homozygous (PubMed=17363600; Cosmic-CLP=1331035; DepMap=ACH-000365). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Proteomics; Subcellular; Cell surface. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq virome analysis. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0%; Native American=1.07%; East Asian, North=0%; East Asian, South=0.49%; South Asian=0%; European, North=60.53%; European, South=37.92% (PubMed=30894373). CC Discontinued: ICLC; HTL10002; true. CC Derived from site: In situ; Peritoneal effusion; UBERON=UBERON_0001268. ST Source(s): ATCC=CRL-2957; Cosmic-CLP=1331035; DSMZ=ACC-495; PubMed=25877200 ST Amelogenin: X,Y ST CSF1PO: 12 ST D13S317: 11,12 ST D16S539: 11,13 ST D18S51: 14,16 ST D19S433: 14 ST D21S11: 29,30 ST D2S1338: 17,19 ST D3S1358: 15,16 ST D5S818: 11,12 ST D7S820: 8,11 ST D8S1179: 13 ST FGA: 19,21 ST Penta D: 9,14 ST Penta E: 7,11 ST TH01: 6,9.3 ST TPOX: 9,11 ST vWA: 18,19 DI NCIt; C36080; Diffuse large B-cell lymphoma germinal center B-cell type DI ORDO; Orphanet_544; Diffuse large B-cell lymphoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 38Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 47 CH CVCL_KU32 ! SU-DHL-4/12V CH CVCL_E1CE ! Ubigene SU-DHL-4 SGK1 KO // RX PubMed=20889926; DOI=10.1182/blood-2010-06-290437; PMCID=PMC3037744; RA Pham, Lan V. RA Fu, Ling-Chen RA Tamayo, Archito T. RA Bueso-Ramos, Carlos E. RA Drakos, Elias RA Vega-Vazquez, Francisco RA Medeiros, L. Jeffrey RA Ford, Richard Joseph Jr. RT "Constitutive BR3 receptor signaling in diffuse, large B-cell RT lymphomas stabilizes nuclear factor-kappaB-inducing kinase while RT activating both canonical and alternative nuclear factor-kappaB RT pathways."; RL Blood 117:200-210(2011). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=12169673; DOI=10.1016/S1525-1578(10)60693-9; PMCID=PMC1906980; RA Robetorye, Ryan S. RA Bohling, Sandra Dawn RA Morgan, John W. RA Fillmore, G. Chris RA Lim, Megan S. RA Elenitoba-Johnson, Kojo Seys John RT "Microarray analysis of B-cell lymphoma cell lines with the RT t(14;18)."; RL J. Mol. Diagn. 4:123-136(2002). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=26727417; DOI=10.3109/10428194.2015.1108414; RA Drexler, Hans Gunther RA Eberth, Sonja RA Nagel, Stefan RA MacLeod, Roderick A.F. RT "Malignant hematopoietic cell lines: in vitro models for double-hit RT B-cell lymphomas."; RL Leuk. Lymphoma 57:1015-1020(2016). // RX PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x; PMCID=PMC5921886; RA Takizawa, Jun RA Suzuki, Ritsuro RA Kuroda, Hiroyuki RA Utsunomiya, Atae RA Kagami, Yoshitoyo RA Joh, Tatsuroh RA Aizawa, Yoshifusa RA Ueda, Ryuzo RA Seto, Masao RT "Expression of the TCL1 gene at 14q32 in B-cell malignancies but not RT in adult T-cell leukemia."; RL Jpn. J. Cancer Res. 89:712-718(1998). // RX PubMed=30165192; DOI=10.1016/j.canlet.2018.08.020; RA Qu, Chang-Ju RA Kunkalla, Kranthi RA Vaghefi, Amineh RA Frederiksen, John K. RA Liu, Ya-Dong RA Chapman, Jennifer Rose RA Blonska, Marzenna RA Bernal-Mizrachi, Leon RA Alderuccio, Juan Pablo RA Lossos, Izidore S. RA Landgraf, Ralf RA Vega-Vazquez, Francisco RT "Smoothened stabilizes and protects TRAF6 from degradation: a novel RT non-canonical role of smoothened with implications in lymphoma RT biology."; RL Cancer Lett. 436:149-158(2018). // RX PubMed=177185; DOI=10.1002/1097-0142(197605)37:5<2158::AID-CNCR2820370503>3.0.CO;2-F; RA Epstein, Alan L. RA Herman, Mary M. RA Kim, Hun RA Dorfman, Ronald Frederick RA Kaplan, Henry Seymour RT "Biology of the human malignant lymphomas. III. Intracranial RT heterotransplantation in the nude, athymic mouse."; RL Cancer 37:2158-2176(1976). // RX PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x; RA Siebert, Reiner RA Willers, Christoph P. RA Schramm, Alexander RA Fossa, Alexander RA Dresen, Irina M. Gana RA Uppenkamp, Michael J. RA Nowrousian, Mohammad Resa RA Seeber, Siegfried RA Opalka, Bertram RT "Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and RT lymphoblastic leukaemia cell lines."; RL Br. J. Haematol. 91:350-354(1995). // RX PubMed=28356514; DOI=10.1073/pnas.1700682114; PMCID=PMC5393253; RA Chen, Jing RA Zhang, Yong RA Petrus, Michael N. RA Xiao, Wen-Ming RA Nicolae, Alina RA Raffeld, Mark RA Pittaluga, Stefania RA Bamford, Richard N. RA Nakagawa, Masao RA Ouyang, Sunny Tian-Yi RA Epstein, Alan L. RA Kadin, Marshall Edward RA Del Mistro, Annarose RA Woessner, Richard D. RA Jaffe, Elaine Sarkin RA Waldmann, Thomas Alexander RT "Cytokine receptor signaling is required for the survival of ALK- RT anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 RT mutations."; RL Proc. Natl. Acad. Sci. U.S.A. 114:3975-3980(2017). // RX PubMed=83902; DOI=10.1002/1097-0142(197901)43:1<1::AID-CNCR2820430102>3.0.CO;2-M; RA Kaplan, Henry Seymour RA Goodenow, Robert S. RA Gartner, Suzanne RA Bieber, Marcia M. RT "Biology and virology of the human malignant lymphomas: 1st Milford D. RT Schulz lecture."; RL Cancer 43:1-24(1979). // RX PubMed=30629668; DOI=10.1371/journal.pone.0210404; PMCID=PMC6328144; RA Uphoff, Cord C. RA Pommerenke, Claudia RA Denkmann, Sabine A. RA Drexler, Hans Gunther RT "Screening human cell lines for viral infections applying RNA-Seq data RT analysis."; RL PLoS ONE 14:e0210404.1-e0210404.22(2019). // RX PubMed=25355872; DOI=10.1128/JVI.02570-14; PMCID=PMC4301145; RA Cao, Su-Bing RA Strong, Michael J. RA Wang, Xia RA Moss, Walter N. RA Concha, Monica RA Lin, Zhen RA O'Grady, Tina RA Baddoo, Melody RA Fewell, Claire RA Renne, Rolf RA Flemington, Erik K. RT "High-throughput RNA sequencing-based virome analysis of 50 lymphoma RT cell lines from the Cancer Cell Line Encyclopedia project."; RL J. Virol. 89:713-729(2015). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=29416618; DOI=10.18632/oncotarget.20378; PMCID=PMC5787470; RA Liu, Wei RA Chen, Juan RA Tamayo, Archito T. RA Ruan, Chang-Geng RA Li, Li RA Zhou, Shou-Hao RA Shen, Chan RA Young, Ken H. RA Westin, Jason RA Davis, Richard E. RA Hu, Shi-Min RA Medeiros, L. Jeffrey RA Ford, Richard Joseph Jr. RA Pham, Lan V. RT "Preclinical efficacy and biological effects of the oral proteasome RT inhibitor ixazomib in diffuse large B-cell lymphoma."; RL Oncotarget 9:346-360(2018). // RX DOI=10.1016/B978-0-12-221970-2.50457-5; RA Drexler, Hans Gunther RT "The leukemia-lymphoma cell line factsbook."; RL (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001). // RX PubMed=18357372; DOI=10.3892/or.19.4.889; RA Pop, Iliodora RA Pop, Laurentiu RA Vitetta, Ellen S. RA Ghetie, Maria-Ana RT "Generation of multidrug resistant lymphoma cell lines stably RT expressing P-glycoprotein."; RL Oncol. Rep. 19:889-895(2008). // RX PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1; RA Drexler, Hans Gunther RA Gaedicke, Gerhard RA Minowada, Jun RT "Isoenzyme studies in human leukemia-lymphoma cell lines -- III. RT Beta-hexosaminidase (E.C. 3.2.1.30)."; RL Leuk. Res. 9:549-559(1985). // RX PubMed=20628145; DOI=10.1182/blood-2010-05-282780; PMCID=PMC2995356; RA Green, Michael Richard RA Monti, Stefano RA Rodig, Scott J. RA Juszczynski, Przemyslaw RA Currie, Treeve RA O'Donnell, Evan RA Chapuy, Bjoern RA Takeyama, Kunihiko RA Neuberg, Donna RA Golub, Todd Robert RA Kutok, Jeffery L. RA Shipp, Margaret Ann RT "Integrative analysis reveals selective 9p24.1 amplification, RT increased PD-1 ligand expression, and further induction via JAK2 in RT nodular sclerosing Hodgkin lymphoma and primary mediastinal large RT B-cell lymphoma."; RL Blood 116:3268-3277(2010). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=17363600; DOI=10.1158/0008-5472.CAN-06-3254; RA Strauss, Sandra J. RA Higginbottom, Karen RA Juliger, Simone RA Maharaj, Lenushka RA Allen, Paul RA Schenkein, David RA Lister, Thomas Andrew RA Joel, Simon P. RT "The proteasome inhibitor bortezomib acts independently of p53 and RT induces cell death via apoptosis and mitotic catastrophe in B-cell RT lymphoma cell lines."; RL Cancer Res. 67:2783-2790(2007). // RX PubMed=20054396; DOI=10.1038/nature08638; PMCID=PMC2845535; RA Davis, R. Eric RA Ngo, Vu N. RA Lenz, Georg RA Tolar, Pavel RA Young, Ryan M. RA Romesser, Paul Bernard RA Kohlhammer, Holger RA Lamy, Laurence RA Zhao, Hong RA Yang, Yan-Dan RA Xu, Wei-Hong RA Shaffer, Arthur L. 3rd RA Wright, George RA Xiao, Wen-Ming RA Powell, John I. RA Jiang, Jian-Kang RA Thomas, Craig J. RA Rosenwald, Andreas RA Ott, German RA Muller-Hermelink, Hans-Konrad RA Gascoyne, Randy D. RA Connors, Joseph M. RA Johnson, Nathalie A. RA Rimsza, Lisa M. RA Campo, Elias RA Jaffe, Elaine Sarkin RA Wilson, Wyndham H. RA Delabie, Jan RA Smeland, Erlend Bremertun RA Fisher, Richard I. RA Braziel, Rita Merle RA Tubbs, Raymond Roy RA Cook, James R. RA Weisenburger, Dennis D. RA Chan, Wing-Chung RA Pierce, Susan Keen RA Staudt, Louis Michael RT "Chronic active B-cell-receptor signalling in diffuse large B-cell RT lymphoma."; RL Nature 463:88-92(2010). // RX PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786; RA Tan, Kar-Tong RA Ding, Ling-Wen RA Sun, Qiao-Yang RA Lao, Zhen-Tang RA Chien, Wenwen RA Ren, Xi RA Xiao, Jin-Fen RA Loh, Xin-Yi RA Xu, Liang RA Lill, Michael RA Mayakonda, Anand RA Lin, De-Chen RA Yang, Henry He RA Koeffler, Harold Phillip RT "Profiling the B/T cell receptor repertoire of lymphocyte derived cell RT lines."; RL BMC Cancer 18:940.1-940.13(2018). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347; RA Bausch-Fluck, Damaris RA Hofmann, Andreas RA Bock, Thomas RA Frei, Andreas P. RA Cerciello, Ferdinando RA Jacobs, Andrea RA Moest, Hansjoerg RA Omasits, Ulrich RA Gundry, Rebekah L. RA Yoon, Charles RA Schiess, Ralph RA Schmidt, Alexander RA Mirkowska, Paulina RA Hartlova, Anetta Svitorka RA Van Eyk, Jennifer Eileen RA Bourquin, Jean-Pierre RA Aebersold, Ruedi RA Boheler, Kenneth R. RA Zandstra, Peter W. RA Wollscheid, Bernd RT "A mass spectrometric-derived cell surface protein atlas."; RL PLoS ONE 10:e0121314.1-e0121314.22(2015). // RX PubMed=214220; DOI=10.1002/1097-0142(197811)42:5<2379::AID-CNCR2820420539>3.0.CO;2-4; RA Epstein, Alan L. RA Levy, Ronald RA Kim, Hun RA Henle, Werner RA Henle, Gertrude Szpingier RA Kaplan, Henry Seymour RT "Biology of the human malignant lymphomas. IV. Functional RT characterization of ten diffuse histiocytic lymphoma cell lines."; RL Cancer 42:2379-2391(1978). // RX DOI=10.11418/jtca1981.15.4_211; RA Matsuo, Yoshinobu RA Okochi, Ayumi RA Ariyasu, Toshio RA Iimura, Emi RA Ohno, Tadao RT "Identification of cell lines with variable numbers of tandem repeat RT (VNTR) amplified by polymerase chain reaction."; RL Tissue Cult. Res. Commun. 15:211-219(1996). // RX PubMed=3881165; DOI=10.1016/0165-4608(85)90186-4; RA Kaiser-McCaw Hecht, Barbara RA Epstein, Alan L. RA Berger, Carol S. RA Kaplan, Henry Seymour RA Hecht, Frederick RT "Histiocytic lymphoma cell lines: immunologic and cytogenetic RT studies."; RL Cancer Genet. Cytogenet. 14:205-218(1985). // RX PubMed=2875799; DOI=10.1016/0092-8674(86)90362-4; RA Cleary, Michael L. RA Smith, Stephen D. RA Sklar, Jeffrey RT "Cloning and structural analysis of cDNAs for bcl-2 and a hybrid RT bcl-2/immunoglobulin transcript resulting from the t(14;18) RT translocation."; RL Cell 47:19-28(1986). // RX PubMed=29666304; DOI=10.1158/1078-0432.CCR-17-3004; RA Pham, Lan V. RA Huang, Sheng-Jian RA Zhang, Hui RA Zhang, Jun RA Bell, Taylor RA Zhou, Shou-Hao RA Pogue, Elizabeth RA Ding, Zhi-Yong RA Lam, Laura RA Westin, Jason RA Davis, R. Eric RA Young, Ken H. RA Medeiros, L. Jeffrey RA Ford, Richard Joseph Jr. RA Nomie, Krystle RA Zhang, Leo RA Wang, Michael RT "Strategic therapeutic targeting to overcome venetoclax resistance in RT aggressive B-cell lymphomas."; RL Clin. Cancer Res. 24:3967-3980(2018). // RX PubMed=8957066; DOI=10.1111/j.1349-7006.1996.tb03112.x; PMCID=PMC5920998; RA Kawasaki, Nobuhiro RA Matsuo, Yoshinobu RA Yoshino, Tadashi RA Yanai, Hiroyuki RA Oka, Takashi RA Teramoto, Norihiro RA Liu, Cao RA Kondo, Eisaku RA Minowada, Jun RA Akagi, Tadaatsu RT "Metastatic potential of lymphoma/leukemia cell lines in SCID mice is RT closely related to expression of CD44."; RL Jpn. J. Cancer Res. 87:1070-1077(1996). // RX PubMed=9787181; DOI=10.1182/blood.V92.9.3410; RA Sakai, Akira RA Thieblemont, Catherine RA Wellmann, Axel RA Jaffe, Elaine Sarkin RA Raffeld, Mark RT "PTEN gene alterations in lymphoid neoplasms."; RL Blood 92:3410-3415(1998). // RX PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x; RA Drexler, Hans Gunther RA Gaedicke, Gerhard RA Minowada, Jun RT "Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid RT phosphatase."; RL Leuk. Res. 9:537-548(1985). // RX PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1; RA Inoue, Kaoru RA Kohno, Takashi RA Takakura, Satoshi RA Hayashi, Yasuhide RA Mizoguchi, Hideaki RA Yokota, Jun RT "Corrigendum to 'Frequent microsatellite instability and BAX mutations RT in T cell acute lymphoblastic leukemia cell lines' Leukemia Research 24 RT (2000), 255-262."; RL Leuk. Res. 25:275-278(2001). // RX PubMed=23292937; DOI=10.1073/pnas.1205299110; PMCID=PMC3557051; RA Zhang, Jenny RA Grubor, Vladimir RA Love, Cassandra L. RA Banerjee, Anjishnu RA Richards, Kristy L. RA Mieczkowski, Piotr Andrzej RA Dunphy, Cherie RA Choi, William Wai-Lap RA Au, Wing Yan RA Srivastava, Gopesh RA Lugar, Patricia Lynne RA Rizzieri, David A. RA Lagoo, Anand S. RA Bernal-Mizrachi, Leon RA Mann, Karen P. RA Flowers, Christopher Robert RA Naresh, Kikkeri N. RA Evens, Andrew M. RA Gordon, Leo I. RA Czader, Magdalena Beata RA Gill, Javed Iqbal RA Hsi, Eric Darryl RA Liu, Qing-Quan RA Fan, Alice RA Walsh, Katherine RA Jima, Dereje RA Smith, Lisa L. RA Johnson, Amy J. RA Byrd, John C. RA Luftig, Micah Alan RA Ni, Ting RA Zhu, Jun RA Chadburn, Amy RA Levy, Shawn RA Dunson, David Brian RA Dave, Sandeep S. RT "Genetic heterogeneity of diffuse large B-cell lymphoma."; RL Proc. Natl. Acad. Sci. U.S.A. 110:1398-1403(2013). // RX PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646; RA Quentmeier, Hilmar RA Pommerenke, Claudia RA Dirks, Wilhelm Gerhard RA Eberth, Sonja RA Koeppel, Max RA MacLeod, Roderick A.F. RA Nagel, Stefan RA Steube, Klaus G. RA Uphoff, Cord C. RA Drexler, Hans Gunther RT "The LL-100 panel: 100 cell lines for blood cancer studies."; RL Sci. Rep. 9:8218.1-8218.14(2019). // RX PubMed=19278952; DOI=10.1182/blood-2009-01-202028; PMCID=PMC3401058; RA Li, Cheng RA Kim, Sang-Woo RA Rai, Deepak RA Bolla, Aswani R. RA Adhvaryu, Siddharth RA Kinney, Marsha C. RA Robetorye, Ryan S. RA Aguiar, Ricardo C.T. RT "Copy number abnormalities, MYC activity, and the genetic fingerprint RT of normal B cells mechanistically define the microRNA profile of RT diffuse large B-cell lymphoma."; RL Blood 113:6681-6690(2009). // RX PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4; RA Inoue, Kaoru RA Kohno, Takashi RA Takakura, Satoshi RA Hayashi, Yasuhide RA Mizoguchi, Hideaki RA Yokota, Jun RT "Frequent microsatellite instability and BAX mutations in T cell acute RT lymphoblastic leukemia cell lines."; RL Leuk. Res. 24:255-262(2000). // RX PubMed=371794; RA Epstein, Alan L. RA Kaplan, Henry Seymour RT "Feeder layer and nutritional requirements for the establishment and RT cloning of human malignant lymphoma cell lines."; RL Cancer Res. 39:1748-1759(1979). // RX PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0; RA Drexler, Hans Gunther RA Gaedicke, Gerhard RA Minowada, Jun RT "Isoenzyme studies in human leukemia-lymphoma cell lines -- 1. RT Carboxylic esterase."; RL Leuk. Res. 9:209-229(1985). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). //