ID   SGC-7901
AC   CVCL_0520
SY   SGC 7901; SGC7901
DR   BTO; BTO:0002392
DR   EFO; EFO_0006293
DR   MCCL; MCC:0000418
DR   ChEMBL-Cells; CHEMBL3307739
DR   ChEMBL-Targets; CHEMBL614909
DR   GEO; GSM844685
DR   GEO; GSM1374869
DR   PubChem_Cell_line; CVCL_0520
DR   TOKU-E; 3764
DR   Wikidata; Q54953170
RX   DOI=10.1007/978-4-431-68252-3_114;
RX   DOI=10.1016/B978-0-12-333530-2.50014-9;
RX   DOI=10.1360/sb1982-27-12-1355;
RX   DOI=10.11569/wcjd.v19.i12.1219;
RX   PubMed=6443274;
RX   PubMed=16038636;
RX   PubMed=16525997;
RX   PubMed=22576950;
RX   PubMed=26116706;
RX   PubMed=27917905;
RX   PubMed=28498440;
RX   PubMed=28851942;
RX   PubMed=29717028;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28851942). Originally thought to originate from the lymph node of a 56 year old female patient with a gastric carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00577.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Proteome analysis by 2D-DE/MS.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: Formerly the CCRID database had 2 entries describing this cell line (3111C0001CCC000236, 3131C0001000700046). They were one of the sources for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID; PubMed=26116706; PubMed=28851942; PubMed=29717028
ST   Amelogenin: X
ST   CSF1PO: 9,10 (PubMed=26116706; PubMed=29717028)
ST   CSF1PO: 10 (CCRID; PubMed=28851942)
ST   D12S391: 20,25
ST   D13S317: 12,13.3 (PubMed=26116706; PubMed=29717028)
ST   D13S317: 13.3 (CCRID; PubMed=28851942)
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13 (CCRID; PubMed=28851942)
ST   D19S433: 13,14 (PubMed=26116706; PubMed=29717028)
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18 (CCRID; PubMed=26116706; PubMed=29717028)
ST   D3S1358: 16,18 (PubMed=28851942)
ST   D5S818: 11,12
ST   D6S1043: 18,19
ST   D7S820: 8,12 (PubMed=26116706; PubMed=29717028)
ST   D7S820: 12 (CCRID; PubMed=28851942)
ST   D8S1179: 12 (CCRID; PubMed=28851942)
ST   D8S1179: 12,13 (PubMed=26116706; PubMed=29717028)
ST   FGA: 18,21 (CCRID; PubMed=28851942)
ST   FGA: 21 (PubMed=26116706; PubMed=29717028)
ST   Penta D: 8,15
ST   Penta E: 7,17
ST   TH01: 7
ST   TPOX: 8,12 (PubMed=26116706; PubMed=29717028)
ST   TPOX: 12 (CCRID; PubMed=28851942)
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 26
RX   DOI=10.1007/978-4-431-68252-3_114;
RA   Wang L.-B., Qian B.-W., Xia Y.-X.;
RT   "Establishment of human gastric cancer cell line (SGC-7901)
RT   intraperitoneally transplantable in nude mice.";
RL   (In) Recent advances in management of digestive cancers; Toshio T. (eds.); pp.416-418; Springer; Tokyo (1993).
RX   DOI=10.1016/B978-0-12-333530-2.50014-9;
RA   Sekiguchi M., Suzuki T.;
RT   "Gastric tumor cell lines.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.287-316; Academic Press; New York (1994).
RX   DOI=10.1360/sb1982-27-12-1355;
RA   Yang J.-L., Shen Z.-M., Han J.-X.;
RT   "A study on the biological characteristics of an established human
RT   gastric adenocarcinoma cell line (SGC-7901).";
RL   Ke Xue Tong Bao 27:1355-1358(1982).
RX   DOI=10.11569/wcjd.v19.i12.1219;
RA   Chen G., Wang Q.-R., Qiu H., Ke S.-D., Xiang Y., Hu S.-M.;
RT   "Relationship of cellular drug resistance to proportion of side
RT   population cells and expression of Mdr1 and ERCC1 in human gastric
RT   cell line SGC7901/OXA.";
RL   Shi Jie Hua Ren Xiao Hua Za Zhi 19:1219-1224(2011).
RX   PubMed=6443274;
RA   Lin C.-H., Fu Z.-M., Liu Y.-L., Yang J.-L., Xu J.-F., Chen Q.-S.,
RA   Chen H.-M.;
RT   "Investigation of SGC-7901 cell line established from human gastric
RT   carcinoma cells.";
RL   Chin. Med. J. 97:831-834(1984).
RX   PubMed=16038636; DOI=10.1111/j.1745-7254.2005.00149.x;
RA   Tang X.-Q., Bi H., Feng J.-Q., Cao J.-G.;
RT   "Effect of curcumin on multidrug resistance in resistant human gastric
RT   carcinoma cell line SGC7901/VCR.";
RL   Acta Pharmacol. Sin. 26:1009-1016(2005).
RX   PubMed=16525997; DOI=10.1002/pmic.200402031;
RA   Yang Y.-X., Xiao Z.-Q., Chen Z.-C., Zhang G.-Y., Yi H., Zhang P.-F.,
RA   Li J.-L., Zhu G.;
RT   "Proteome analysis of multidrug resistance in vincristine-resistant
RT   human gastric cancer cell line SGC7901/VCR.";
RL   Proteomics 6:2009-2021(2006).
RX   PubMed=22576950; DOI=10.1007/s13277-012-0406-3;
RA   Xu Y.-Y., Mao X.-Y., Song Y.-X., Zhao F., Wang Z.-N., Zhang W.-X.,
RA   Xu H.-M., Jin F.;
RT   "Midkine confers adriamycin resistance in human gastric cancer
RT   cells.";
RL   Tumor Biol. 33:1543-1548(2012).
RX   PubMed=26116706; DOI=10.1096/fj.14-266718;
RA   Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.;
RT   "Genetic profiling reveals an alarming rate of cross-contamination
RT   among human cell lines used in China.";
RL   FASEB J. 29:4268-4272(2015).
RX   PubMed=27917905; DOI=10.1038/srep38376;
RA   Chen Z.-Z., Li W.-M., Zhang Y., Yu M., Shan L.-F., Yuan D.-Z.,
RA   Liu F.-R., Fang J.;
RT   "Establishment of a gastric cancer subline with high metastatic
RT   potential using a novel microfluidic system.";
RL   Sci. Rep. 6:38376-38376(2016).
RX   PubMed=28498440; DOI=10.3892/ijo.2017.3983;
RA   Zhuang K., Zhang L.-X., Zhang X., Tang H.-L., Zhang J., Yan Y., Han K.,
RA   Guo H.-Q.;
RT   "Gastrin induces multidrug resistance via the degradation of p27Kip1
RT   in the gastric carcinoma cell line SGC7901.";
RL   Int. J. Oncol. 50:2091-2100(2017).
RX   PubMed=28851942; DOI=10.1038/s41598-017-09660-w;
RA   Bian X.-C., Yang Z.-L., Feng H.-L., Sun H., Liu Y.-Q.;
RT   "A combination of species identification and STR profiling identifies
RT   cross-contaminated cells from 482 human tumor cell lines.";
RL   Sci. Rep. 7:9774-9774(2017).
RX   PubMed=29717028; DOI=10.1042/BSR20180277;
RA   Zhang Y.-Q., Yu S.-T., Zhang Z.-Z., Zhao G., Xu J.;
RT   "Long non-coding RNA AK096174 promotes cell proliferation and invasion
RT   in gastric cancer by regulating WDR66 expression.";
RL   Biosci. Rep. 38:BSR20180277.1-BSR20180277.12(2018).