ID   NCI-H157
AC   CVCL_0463
SY   NCl-H157; NCI H157; H157; H-157; NCI-157; NCIH157DM; H157DM
DR   BTO; BTO_0002283
DR   CLO; CLO_0037032
DR   EFO; EFO_0003118
DR   MCCL; MCC:0000360
DR   ArrayExpress; E-MTAB-783
DR   ATCC; CRL-5802
DR   BioSample; SAMN03151855
DR   BioSample; SAMN03471738
DR   cancercelllines; CVCL_0463
DR   CCRID; 1101HUM-PUMC000113
DR   ChEMBL-Cells; CHEMBL3307706
DR   ChEMBL-Targets; CHEMBL614783
DR   CLS; 300387
DR   Cosmic; 722053
DR   Cosmic; 724867
DR   Cosmic; 801588
DR   Cosmic; 844816
DR   Cosmic; 852006
DR   Cosmic; 876171
DR   Cosmic; 877258
DR   Cosmic; 903569
DR   Cosmic; 911847
DR   Cosmic; 917987
DR   Cosmic; 929971
DR   Cosmic; 930486
DR   Cosmic; 932921
DR   Cosmic; 934546
DR   Cosmic; 949208
DR   Cosmic; 953987
DR   Cosmic; 980960
DR   Cosmic; 1028954
DR   Cosmic; 1032432
DR   Cosmic; 1146881
DR   Cosmic; 1219061
DR   Cosmic; 1239910
DR   Cosmic; 1320185
DR   Cosmic; 2560227
DR   Cosmic; 2648437
DR   Cosmic; 2668267
DR   Cosmic; 2668329
DR   DepMap; ACH-000921
DR   GEO; GSM62967
DR   GEO; GSM108815
DR   GEO; GSM108816
DR   GEO; GSM253365
DR   GEO; GSM434267
DR   GEO; GSM784238
DR   GEO; GSM794274
DR   GEO; GSM817068
DR   IARC_TP53; 495
DR   IARC_TP53; 28242
DR   IARC_TP53; 28453
DR   IGRhCellID; H157GEO
DR   KCB; KCB 200814YJ
DR   KCLB; 90157
DR   LINCS_LDP; LCL-1596
DR   PRIDE; PXD002556
DR   Progenetix; CVCL_0463
DR   PubChem_Cell_line; CVCL_0463
DR   Wikidata; Q54907822
RX   PubMed=1311061;
RX   PubMed=1563005;
RX   PubMed=3940644;
RX   PubMed=6148444;
RX   PubMed=6270685;
RX   PubMed=6272398;
RX   PubMed=6713399;
RX   PubMed=7972006;
RX   PubMed=8626706;
RX   PubMed=8806092;
RX   PubMed=9649128;
RX   PubMed=10536175;
RX   PubMed=11005564;
RX   PubMed=11369051;
RX   PubMed=12068308;
RX   PubMed=12820372;
RX   PubMed=16187286;
RX   PubMed=19472407;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20557307;
RX   PubMed=20624269;
RX   PubMed=22961666;
RX   PubMed=23381221;
RX   PubMed=25120651;
RX   PubMed=26361996;
RX   PubMed=29681454;
RX   PubMed=30038707;
RX   PubMed=31803961;
RX   PubMed=38180245;
WW   Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/cross-contamination-of-atcc-crl-5802-and-atcc-crl-5860
WW   Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/misidentified-cell-lines-atcc-crl-5802-and-atcc-crl-5860
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. NCI-H157 and NCI-H1264 have been shown to be identical.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00412.
CC   Doubling time: 53 hours (Note=In RPMI 1640 + 10% FBS), 90 hours (Note=In ACL-3 + BSA) (PubMed=3940644); 20.8 hours (PubMed=29681454).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Homozygous (PubMed=30038707; DepMap=ACH-000921).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (PubMed=1311061; PubMed=12068308; DepMap=ACH-000921).
CC   Sequence variation: Mutation; HGNC; HGNC:11100; SMARCA4; Simple; p.Thr58Profs*36 (c.171del); Zygosity=Homozygous (DepMap=ACH-000921).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu35Phefs*8 (c.102_103insT) (c.103_104insT); Zygosity=Heterozygous (PubMed=10536175; PubMed=20557307; DepMap=ACH-000921).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu298Ter (c.892G>T); ClinVar=VCV000093323; Zygosity=Heterozygous (PubMed=1311061; PubMed=10536175; PubMed=20557307; DepMap=ACH-000921).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Proteomics.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; SNP array analysis.
CC   Discontinued: ATCC; CRL-5802; true.
CC   Discontinued: KCLB; 90157; probable.
ST   Source(s): ATCC=CRL-5802; CCRID=1101HUM-PUMC000113; CLS=300387
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D12S391: 20
ST   D13S317: 12
ST   D16S539: 12,13
ST   D18S51: 13,15
ST   D19S433: 11,13
ST   D21S11: 32
ST   D2S1338: 21,22
ST   D3S1358: 17,18
ST   D5S818: 10,13
ST   D6S1043: 17,24
ST   D7S820: 12
ST   D8S1179: 14,16
ST   FGA: 22,23
ST   Penta D: 2.2
ST   Penta E: 7
ST   TH01: 7,9
ST   TPOX: 6,12
ST   vWA: 15
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_3970 ! NCI-H1264
SX   Male
AG   59Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 43
//
RX   PubMed=1311061;
RA   Mitsudomi, Tetsuya
RA   Steinberg, Seth M.
RA   Nau, Marion M.
RA   Carbone, David P.
RA   D'Amico, Domenico
RA   Bodner, Sara M.
RA   Oie, Herbert Kazuto
RA   Linnoila, Ritva Ilona
RA   Mulshine, James L.
RA   Minna, John D.
RA   Gazdar, Adi F.
RT   "p53 gene mutations in non-small-cell lung cancer cell lines and their
RT   correlation with the presence of ras mutations and clinical
RT   features.";
RL   Oncogene 7:171-180(1992).
//
RX   PubMed=1563005;
RA   Giaccone, Giuseppe
RA   Battey, James
RA   Gazdar, Adi F.
RA   Oie, Herbert Kazuto
RA   Draoui, Muriel
RA   Moody, Terry W.
RT   "Neuromedin B is present in lung cancer cell lines.";
RL   Cancer Res. 52:2732s-2736s(1992).
//
RX   PubMed=3940644;
RA   Brower, Martin
RA   Carney, Desmond Niall
RA   Oie, Herbert Kazuto
RA   Gazdar, Adi F.
RA   Minna, John D.
RT   "Growth of cell lines and clinical specimens of human non-small cell
RT   lung cancer in a serum-free defined medium.";
RL   Cancer Res. 46:798-806(1986).
//
RX   PubMed=6148444; DOI=10.1093/jnci/73.4.801;
RA   Morstyn, George
RA   Russo, Angelo
RA   Carney, Desmond Niall
RA   Karawya, Essam
RA   Wilson, Samuel H. Jr.
RA   Mitchell, James B.
RT   "Heterogeneity in the radiation survival curves and biochemical
RT   properties of human lung cancer cell lines.";
RL   J. Natl. Cancer Inst. 73:801-807(1984).
//
RX   PubMed=6270685; DOI=10.1073/pnas.78.7.4591; PMCID=PMC319839;
RA   Cuttitta, Frank
RA   Rosen, Steven T.
RA   Gazdar, Adi F.
RA   Minna, John D.
RT   "Monoclonal antibodies that demonstrate specificity for several types
RT   of human lung cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:4591-4595(1981).
//
RX   PubMed=6272398; DOI=10.1126/science.6272398;
RA   Moody, Terry W.
RA   Pert, Candace Beebe
RA   Gazdar, Adi F.
RA   Carney, Desmond Niall
RA   Minna, John D.
RT   "High levels of intracellular bombesin characterize human small-cell
RT   lung carcinoma.";
RL   Science 214:1246-1248(1981).
//
RX   PubMed=6713399;
RA   Rosen, Steven T.
RA   Mulshine, James L.
RA   Cuttitta, Frank
RA   Fedorko, Joseph
RA   Carney, Desmond Niall
RA   Gazdar, Adi F.
RA   Minna, John D.
RT   "Analysis of human small cell lung cancer differentiation antigens
RT   using a panel of rat monoclonal antibodies.";
RL   Cancer Res. 44:2052-2061(1984).
//
RX   PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163;
RA   Okamoto, Aikou
RA   Demetrick, Douglas J.
RA   Spillare, Elisa A.
RA   Hagiwara, Koichi
RA   Hussain, S. Perwez
RA   Bennett, William P.
RA   Forrester, Kathleen
RA   Gerwin, Brenda Isen
RA   Serrano, Manuel
RA   Beach, David H.
RA   Harris, Curtis Craig
RT   "Mutations and altered expression of p16INK4 in human cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994).
//
RX   PubMed=8626706; DOI=10.1074/jbc.271.19.11477;
RA   Quinn, Kathryn A.
RA   Treston, Anthony M.
RA   Unsworth, Edward J.
RA   Miller, Mae-Jean
RA   Vos, Michele
RA   Grimley, Chris
RA   Battey, James
RA   Mulshine, James L.
RA   Cuttitta, Frank
RT   "Insulin-like growth factor expression in human cancer cell lines.";
RL   J. Biol. Chem. 271:11477-11483(1996).
//
RX   PubMed=8806092; DOI=10.1002/jcb.240630505;
RA   Phelps, Ruby M.
RA   Johnson, Bruce E.
RA   Ihde, Daniel C.
RA   Gazdar, Adi F.
RA   Carbone, David P.
RA   McClintock, Patrick R.
RA   Linnoila, Ritva Ilona
RA   Matthews, Mary J.
RA   Bunn, Paul A. Jr.
RA   Carney, Desmond Niall
RA   Minna, John D.
RA   Mulshine, James L.
RT   "NCI-Navy Medical Oncology Branch cell line data base.";
RL   J. Cell. Biochem. Suppl. 24:32-91(1996).
//
RX   PubMed=9649128; DOI=10.1038/bjc.1998.361; PMCID=PMC2150402;
RA   Yi, Seung
RA   Chen, Jing-Ru
RA   Viallet, Jean
RA   Schwall, Ralph H.
RA   Nakamura, T.
RA   Tsao, Ming-Sound
RT   "Paracrine effects of hepatocyte growth factor/scatter factor on
RT   non-small-cell lung carcinoma cell lines.";
RL   Br. J. Cancer 77:2162-2170(1998).
//
RX   PubMed=10536175; DOI=10.3892/ijo.15.5.927;
RA   Fujita, Takeshi
RA   Kiyama, Masaharu
RA   Tomizawa, Yoshio
RA   Kohno, Takashi
RA   Yokota, Jun
RT   "Comprehensive analysis of p53 gene mutation characteristics in lung
RT   carcinoma with special reference to histological subtypes.";
RL   Int. J. Oncol. 15:927-934(1999).
//
RX   PubMed=11005564; DOI=10.1038/sj.neo.7900094; PMCID=PMC1550293;
RA   Kohno, Takashi
RA   Sato, Takako
RA   Takakura, Satoshi
RA   Takei, Kimiko
RA   Inoue, Kaoru
RA   Nishioka, Michiho
RA   Yokota, Jun
RT   "Mutation and expression of the DCC gene in human lung cancer.";
RL   Neoplasia 2:300-305(2000).
//
RX   PubMed=11369051; DOI=10.1016/S0165-4608(00)00363-0;
RA   Luk, Catherine
RA   Tsao, Ming-Sound
RA   Bayani, Jane
RA   Shepherd, Frances Alice
RA   Squire, Jeremy Andrew
RT   "Molecular cytogenetic analysis of non-small cell lung carcinoma by
RT   spectral karyotyping and comparative genomic hybridization.";
RL   Cancer Genet. Cytogenet. 125:87-99(2001).
//
RX   PubMed=12068308; DOI=10.1038/nature00766;
RA   Davies, Helen R.
RA   Bignell, Graham Robert
RA   Cox, Charles
RA   Stephens, Philip J.
RA   Edkins, Sarah
RA   Clegg, Sheila
RA   Teague, Jon W.
RA   Woffendin, Hayley
RA   Garnett, Mathew J.
RA   Bottomley, William
RA   Davis, Neil
RA   Dicks, Ed
RA   Ewing, Rebecca
RA   Floyd, Yvonne
RA   Gray, Kristian
RA   Hall, Sarah
RA   Hawes, Rachel
RA   Hughes, Jaime
RA   Kosmidou, Vivian
RA   Menzies, Andrew
RA   Mould, Catherine
RA   Parker, Adrian
RA   Stevens, Claire
RA   Watt, Stephen
RA   Hooper, Steven
RA   Wilson, Rebecca
RA   Jayatilake, Hiran
RA   Gusterson, Barry Austin
RA   Cooper, Colin S.
RA   Shipley, Janet M.
RA   Hargrave, Darren
RA   Pritchard-Jones, Kathy
RA   Maitland, Norman J.
RA   Chenevix-Trench, Georgia
RA   Riggins, Gregory J.
RA   Bigner, Darell Doty
RA   Palmieri, Giuseppe
RA   Cossu, Antonio
RA   Flanagan, Adrienne M.
RA   Nicholson, Andrew
RA   Ho, Judy W.C.
RA   Leung, Suet Yi
RA   Yuen, Siu Tsan
RA   Weber, Barbara L.
RA   Seigler, Hilliard Foster
RA   Darrow, Timothy L.
RA   Paterson, Hugh F.
RA   Marais, Richard
RA   Marshall, Christopher John
RA   Wooster, Richard
RA   Stratton, Michael Rudolf
RA   Futreal, P. Andrew
RT   "Mutations of the BRAF gene in human cancer.";
RL   Nature 417:949-954(2002).
//
RX   PubMed=12820372;
RA   Bergqvist, Michael
RA   Brattstrom, Daniel
RA   Gullbo, Joachim
RA   Hesselius, Patrik
RA   Brodin, Ola
RA   Wagenius, Gunnar
RT   "p53 status and its in vitro relationship to radiosensitivity and
RT   chemosensitivity in lung cancer.";
RL   Anticancer Res. 23:1207-1212(2003).
//
RX   PubMed=16187286; DOI=10.1002/ijc.21491;
RA   Garnis, Cathie
RA   Lockwood, William W.
RA   Vucic, Emily
RA   Ge, Ying
RA   Girard, Luc
RA   Minna, John D.
RA   Gazdar, Adi F.
RA   Lam, Stephen
RA   MacAulay, Calum
RA   Lam, Wan L.
RT   "High resolution analysis of non-small cell lung cancer cell lines by
RT   whole genome tiling path array CGH.";
RL   Int. J. Cancer 118:1556-1564(2006).
//
RX   PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846;
RA   Blanco, Raquel
RA   Iwakawa, Reika
RA   Tang, Mo-Ying
RA   Kohno, Takashi
RA   Angulo, Barbara
RA   Pio, Ruben
RA   Montuenga, Luis M.
RA   Minna, John D.
RA   Yokota, Jun
RA   Sanchez-Cespedes, Montse
RT   "A gene-alteration profile of human lung cancer cell lines.";
RL   Hum. Mutat. 30:1199-1206(2009).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680;
RA   Iwakawa, Reika
RA   Kohno, Takashi
RA   Enari, Masatoshi
RA   Kiyono, Tohru
RA   Yokota, Jun
RT   "Prevalence of human papillomavirus 16/18/33 infection and p53
RT   mutation in lung adenocarcinoma.";
RL   Cancer Sci. 101:1891-1896(2010).
//
RX   PubMed=20624269; DOI=10.1186/1756-9966-29-75; PMCID=PMC2907339;
RA   Du, Li-Qin
RA   Schageman, Jeoffrey J.
RA   Irnov, Irnov
RA   Girard, Luc
RA   Hammond, Scott M.
RA   Minna, John D.
RA   Gazdar, Adi F.
RA   Pertsemlidis, Alexander
RT   "MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells
RT   and suggests a possible pathological relationship between SCLCs and
RT   NSCLCs.";
RL   J. Exp. Clin. Cancer Res. 29:75.1-75.12(2010).
//
RX   PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112; PMCID=PMC3567922;
RA   Byers, Lauren Averett
RA   Wang, Jing
RA   Nilsson, Monique B.
RA   Fujimoto, Junya
RA   Saintigny, Pierre
RA   Yordy, John Stuart
RA   Giri, Uma
RA   Peyton, Michael
RA   Fan, You-Hong
RA   Diao, Li-Xia
RA   Masrorpour, Fatemeh
RA   Shen, Li
RA   Liu, Wen-Bin
RA   Duchemann, Boris
RA   Tumula, Praveen
RA   Bhardwaj, Vikas
RA   Welsh, James
RA   Weber, Stephanie
RA   Glisson, Bonnie S.
RA   Kalhor, Neda
RA   Wistuba, Ignacio Ivan
RA   Girard, Luc
RA   Lippman, Scott M.
RA   Mills, Gordon B.
RA   Coombes, Kevin Robert
RA   Weinstein, John N.
RA   Minna, John D.
RA   Heymach, John Victor
RT   "Proteomic profiling identifies dysregulated pathways in small cell
RT   lung cancer and novel therapeutic targets including PARP1.";
RL   Cancer Discov. 2:798-811(2012).
//
RX   PubMed=23381221; DOI=10.3892/or.2013.2266; PMCID=PMC3621652;
RA   Suzuki, Makoto
RA   Shiraishi, Kenji
RA   Eguchi, Ayami
RA   Ikeda, Koei
RA   Mori, Takeshi
RA   Yoshimoto, Kentaro
RA   Ohba, Yasuomi
RA   Yamada, Tatsuya
RA   Ito, Takaaki
RA   Baba, Yoshifumi
RA   Baba, Hideo
RT   "Aberrant methylation of LINE-1, SLIT2, MAL and IGFBP7 in non-small
RT   cell lung cancer.";
RL   Oncol. Rep. 29:1308-1314(2013).
//
RX   PubMed=25120651; DOI=10.3892/ol.2014.2234; PMCID=PMC4114630;
RA   Suzuki, Makoto
RA   Ikeda, Koei
RA   Shiraishi, Kenji
RA   Eguchi, Ayami
RA   Mori, Takeshi
RA   Yoshimoto, Kentaro
RA   Shibata, Hidekatsu
RA   Ito, Takaaki
RA   Baba, Yoshifumi
RA   Baba, Hideo
RT   "Aberrant methylation and silencing of IRF8 expression in non-small
RT   cell lung cancer.";
RL   Oncol. Lett. 8:1025-1030(2014).
//
RX   PubMed=26361996; DOI=10.1016/j.jprot.2015.09.003;
RA   Grundner-Culemann, Kathrin
RA   Dybowski, J. Nikolaj
RA   Klammer, Martin
RA   Tebbe, Andreas
RA   Schaab, Christoph
RA   Daub, Henrik
RT   "Comparative proteome analysis across non-small cell lung cancer cell
RT   lines.";
RL   J. Proteomics 130:1-10(2016).
//
RX   PubMed=29681454; DOI=10.1016/j.cell.2018.03.028; PMCID=PMC5935540;
RA   McMillan, Elizabeth A.
RA   Ryu, Myung-Jeom
RA   Diep, Caroline H.
RA   Mendiratta, Saurabh
RA   Clemenceau, Jean Rene
RA   Vaden, Rachel M.
RA   Kim, Ju-Hwa
RA   Motoyaji, Takashi
RA   Covington, Kyle R.
RA   Peyton, Michael
RA   Huffman, Kenneth
RA   Wu, Xiao-Feng
RA   Girard, Luc
RA   Sung, Yeojin
RA   Chen, Pei-Hsaun
RA   Mallipeddi, Prema Latha
RA   Lee, Joo Young
RA   Hanson, Jordan
RA   Voruganti, Sukesh
RA   Yu, Yunku
RA   Park, Sunho
RA   Sudderth, Jessica
RA   DeSevo, Christopher
RA   Muzny, Donna M.
RA   Doddapaneni, HarshaVardhan
RA   Gazdar, Adi F.
RA   Gibbs, Richard Alexander
RA   Hwang, Tae Hyun
RA   Heymach, John Victor
RA   Wistuba, Ignacio Ivan
RA   Coombes, Kevin Robert
RA   Williams, Noelle S.
RA   Wheeler, David A.
RA   MacMillan, John B.
RA   DeBerardinis, Ralph J.
RA   Roth, Michael G.
RA   Posner, Bruce Arthur
RA   Minna, John D.
RA   Kim, Hyun Seok
RA   White, Michael A.
RT   "Chemistry-first approach for nomination of personalized treatment in
RT   lung cancer.";
RL   Cell 173:864-878.e29(2018).
//
RX   PubMed=30038707; DOI=10.18632/oncotarget.25642; PMCID=PMC6049873;
RA   Du, Li-Qin
RA   Zhao, Zhen-Ze
RA   Suraokar, Milind Bhalchandra
RA   Shelton, Spencer S.
RA   Ma, Xiu-Ye
RA   Hsiao, Tzu-Hung
RA   Minna, John D.
RA   Wistuba, Ignacio Ivan
RA   Pertsemlidis, Alexander
RT   "LMO1 functions as an oncogene by regulating TTK expression and
RT   correlates with neuroendocrine differentiation of lung cancer.";
RL   Oncotarget 9:29601-29618(2018).
//
RX   PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084;
RA   Mulshine, James L.
RA   Ujhazy, Peter
RA   Antman, Melissa
RA   Burgess, Christine M.
RA   Kuzmin, Igor A.
RA   Bunn, Paul A. Jr.
RA   Johnson, Bruce E.
RA   Roth, Jack Alan
RA   Pass, Harvey I.
RA   Ross, Sheila M.
RA   Aldige, Carolyn R.
RA   Wistuba, Ignacio Ivan
RA   Minna, John D.
RT   "From clinical specimens to human cancer preclinical models -- a journey
RT   the NCI-cell line database-25 years later.";
RL   J. Cell. Biochem. 121:3986-3999(2020).
//
RX   PubMed=38180245; DOI=10.1158/1078-0432.CCR-23-2360; PMCID=PMC11061608;
RA   Ng, Jin
RA   Cai, Ling
RA   Girard, Luc
RA   Prall, Owen W.J.
RA   Rajan, Neeha Sulakshi
RA   Khoo, Christine
RA   Batrouney, Ahida
RA   Byrne, David J.
RA   Boyd, Danielle K.
RA   Kersbergen, Ariena J.
RA   Christie, Michael
RA   Minna, John D.
RA   Burr, Marian L.
RA   Sutherland, Kate D.
RT   "Molecular and pathologic characterization of YAP1-expressing small
RT   cell lung cancer cell lines leads to reclassification as
RT   SMARCA4-deficient malignancies.";
RL   Clin. Cancer Res. 30:1846-1858(2024).
//