ID   NCI-H460
AC   CVCL_0459
SY   NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460
DR   BTO; BTO_0002207
DR   CLO; CLO_0003601
DR   CLO; CLO_0008089
DR   EFO; EFO_0003044
DR   MCCL; MCC:0000356
DR   CLDB; cl1548
DR   4DN; 4DNSRZBU6PZA
DR   AddexBio; C0016003/39
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ATCC; HTB-177
DR   BCRC; 60373
DR   BCRJ; 0416
DR   BioGRID_ORCS_Cell_line; 523
DR   BioSample; SAMN03471184
DR   BioSample; SAMN10987808
DR   cancercelllines; CVCL_0459
DR   CCLV; CCLV-RIE 0962
DR   CCRID; 1101HUM-PUMC000355
DR   CCRID; 1102HUM-NIFDC00086
DR   CCRID; 3101HUMSCSP584
DR   CCRID; 3101HUMTCHu205
DR   CCRID; 4201HUM-CCTCC00109
DR   CCTCC; GDC0109
DR   Cell_Model_Passport; SIDM00144
DR   CGH-DB; 199-1
DR   CGH-DB; 9186-4
DR   ChEMBL-Cells; CHEMBL3307677
DR   ChEMBL-Targets; CHEMBL396
DR   CLS; 305020
DR   Cosmic; 722064
DR   Cosmic; 724876
DR   Cosmic; 755469
DR   Cosmic; 844595
DR   Cosmic; 875852
DR   Cosmic; 877263
DR   Cosmic; 877407
DR   Cosmic; 897508
DR   Cosmic; 905943
DR   Cosmic; 911996
DR   Cosmic; 931371
DR   Cosmic; 947356
DR   Cosmic; 980964
DR   Cosmic; 1006534
DR   Cosmic; 1017826
DR   Cosmic; 1028956
DR   Cosmic; 1032436
DR   Cosmic; 1044245
DR   Cosmic; 1047102
DR   Cosmic; 1089231
DR   Cosmic; 1092621
DR   Cosmic; 1146917
DR   Cosmic; 1152502
DR   Cosmic; 1154605
DR   Cosmic; 1188592
DR   Cosmic; 1219077
DR   Cosmic; 1239922
DR   Cosmic; 1305349
DR   Cosmic; 1312334
DR   Cosmic; 1434967
DR   Cosmic; 1436013
DR   Cosmic; 1477420
DR   Cosmic; 1802310
DR   Cosmic; 1870275
DR   Cosmic; 1945869
DR   Cosmic; 1995579
DR   Cosmic; 1998463
DR   Cosmic; 2042872
DR   Cosmic; 2058650
DR   Cosmic; 2125199
DR   Cosmic; 2433756
DR   Cosmic; 2560230
DR   Cosmic; 2630413
DR   Cosmic; 2664114
DR   Cosmic; 2772154
DR   Cosmic-CLP; 905943
DR   DepMap; ACH-000463
DR   DSMZ; ACC-737
DR   DSMZCellDive; ACC-737
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001002554
DR   ENCODE; ENCBS279XIV
DR   ENCODE; ENCBS398KLJ
DR   ENCODE; ENCBS428IIT
DR   ENCODE; ENCBS446PPO
DR   ENCODE; ENCBS460OUE
DR   ENCODE; ENCBS514AAA
DR   ENCODE; ENCBS515AAA
DR   ENCODE; ENCBS641PGO
DR   ENCODE; ENCBS657CEJ
DR   ENCODE; ENCBS686KKP
DR   ENCODE; ENCBS798ZFS
DR   ENCODE; ENCBS814QPR
DR   FANTOM5_SSTAR; 10839-111E2
DR   GDSC; 905943
DR   GEO; GSM2152
DR   GEO; GSM50216
DR   GEO; GSM50279
DR   GEO; GSM108853
DR   GEO; GSM108854
DR   GEO; GSM206493
DR   GEO; GSM253335
DR   GEO; GSM274737
DR   GEO; GSM274738
DR   GEO; GSM385522
DR   GEO; GSM385533
DR   GEO; GSM434334
DR   GEO; GSM513936
DR   GEO; GSM514322
DR   GEO; GSM743455
DR   GEO; GSM750809
DR   GEO; GSM784193
DR   GEO; GSM794288
DR   GEO; GSM799343
DR   GEO; GSM799406
DR   GEO; GSM817074
DR   GEO; GSM827469
DR   GEO; GSM844651
DR   GEO; GSM844652
DR   GEO; GSM847076
DR   GEO; GSM887430
DR   GEO; GSM888510
DR   GEO; GSM1153414
DR   GEO; GSM1178473
DR   GEO; GSM1178474
DR   GEO; GSM1178475
DR   GEO; GSM1181352
DR   GEO; GSM1181361
DR   GEO; GSM1374746
DR   GEO; GSM1374747
DR   GEO; GSM1374748
DR   GEO; GSM1557134
DR   GEO; GSM2124676
DR   IARC_TP53; 21083
DR   IGRhCellID; NCI-H460%20GEO
DR   IZSLER; BS TCL 197
DR   KCB; KCB 2010102YJ
DR   KCLB; 30177
DR   LiGeA; CCLE_338
DR   LINCS_LDP; LCL-1784
DR   Lonza; 728
DR   NCI-DTP; NCI-H460
DR   PharmacoDB; NCIH460_1114_2019
DR   PRIDE; PXD005940
DR   PRIDE; PXD005942
DR   PRIDE; PXD005946
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0459
DR   PubChem_Cell_line; CVCL_0459
DR   SKY/M-FISH/CGH; 2798
DR   Wikidata; Q54908057
RX   PubMed=1311061;
RX   PubMed=1563005;
RX   PubMed=2041050;
RX   PubMed=2388294;
RX   PubMed=3335022;
RX   PubMed=3940644;
RX   PubMed=7718330;
RX   PubMed=8385084;
RX   PubMed=8626706;
RX   PubMed=8806092;
RX   PubMed=9331090;
RX   PubMed=10358721;
RX   PubMed=10700174;
RX   PubMed=11030152;
RX   PubMed=11551417;
RX   PubMed=11583962;
RX   PubMed=12068308;
RX   PubMed=12794755;
RX   PubMed=15746151;
RX   PubMed=15748285;
RX   PubMed=15900046;
RX   PubMed=17088437;
RX   PubMed=17332333;
RX   PubMed=18083107;
RX   PubMed=19372543;
RX   PubMed=19472407;
RX   PubMed=19941903;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20510196;
RX   PubMed=20557307;
RX   PubMed=22068913;
RX   PubMed=22336246;
RX   PubMed=22347499;
RX   PubMed=22384151;
RX   PubMed=22460905;
RX   PubMed=22628656;
RX   PubMed=22961666;
RX   PubMed=23381221;
RX   PubMed=23856246;
RX   PubMed=23933261;
RX   PubMed=24135919;
RX   PubMed=24279929;
RX   PubMed=24465237;
RX   PubMed=24670534;
RX   PubMed=25120651;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=26589293;
RX   PubMed=27377824;
RX   PubMed=27397505;
RX   PubMed=27807467;
RX   PubMed=28196595;
RX   PubMed=28408844;
RX   PubMed=29444439;
RX   PubMed=29681454;
RX   PubMed=30038707;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31803961;
RX   PubMed=31978347;
RX   PubMed=33425914;
RX   PubMed=35839778;
RX   PubMed=38861359;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm
WW   Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=12
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-613.html
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/lung-cancer-xenograft/h460-xenograft-model/
WW   Provider; BRICS; BRICS0123; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3926
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: EGFR genetic alteration cell panel (ATCC TCP-1027).
CC   Part of: JFCR39 cancer cell line panel.
CC   Part of: KuDOS 95 cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: NCI-60 cancer cell line panel.
CC   Population: Caucasian.
CC   Characteristics: Expresses HPRT1 at the surface of the cell membrane (PubMed=28408844).
CC   Doubling time: 33 hours (Note=In RPMI 1640 + 10% FBS), 60 hours (Note=In ACL-3), 42 hours (Note=In ACL-3 + BSA) (PubMed=3940644); 19 hours (PubMed=7718330); 0.8 day (PubMed=11551417); 21.5 hours (PubMed=29681454); 18.39 +- 1.35 hours (PubMed=33425914); ~23 hours (DSMZ=ACC-737); 17.8 hours (NCI-DTP=NCI-H460).
CC   HLA typing: A*24,68; B*35,51; C*03,15; DQB1*03:01:01,05:01:01; DRB1*01,04 (PubMed=15748285).
CC   HLA typing: A*24:02,68:01; B*35:01,51:01; C*03:03,15:02 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000045117; Zygosity=Homozygous (PubMed=12068308; PubMed=12794755; PubMed=17088437; DepMap=ACH-000463).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (PubMed=17088437).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (PubMed=17088437).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=1311061; PubMed=15900046; PubMed=20557307).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Metabolomics.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Phenotyping; Fluorescent probe library screening.
CC   Omics: Proteomics.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; PTM; Phosphorylation.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; lncRNA profiling; RT-qPCR platform.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=1.96%; East Asian, South=0%; South Asian=0.15%; European, North=65.65%; European, South=32.24% (PubMed=30894373).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): AddexBio=C0016003/39; ATCC=HTB-177; CCRID; Cosmic-CLP=905943; DSMZ=ACC-737; KCLB=30177; PubMed=19372543; PubMed=25877200; PubMed=33425914; Technion Genomics Center
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D10S1248: 13
ST   D12S391: 21
ST   D13S317: 13
ST   D16S539: 9
ST   D18S51: 13,15
ST   D19S433: 14
ST   D1S1656: 11,14.3
ST   D21S11: 30
ST   D22S1045: 17
ST   D2S1338: 17,25
ST   D2S441: 11,11.3
ST   D3S1358: 15,18
ST   D5S818: 9,10
ST   D7S820: 9,12
ST   D8S1179: 12
ST   DYS391: 11
ST   FGA: 21,23
ST   Penta D: 11,13
ST   Penta E: 5
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 17
DI   NCIt; C4450; Lung large cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 52
//
RX   PubMed=1311061;
RA   Mitsudomi, Tetsuya
RA   Steinberg, Seth M.
RA   Nau, Marion M.
RA   Carbone, David P.
RA   D'Amico, Domenico
RA   Bodner, Sara M.
RA   Oie, Herbert Kazuto
RA   Linnoila, Ritva Ilona
RA   Mulshine, James L.
RA   Minna, John D.
RA   Gazdar, Adi F.
RT   "p53 gene mutations in non-small-cell lung cancer cell lines and their
RT   correlation with the presence of ras mutations and clinical
RT   features.";
RL   Oncogene 7:171-180(1992).
//
RX   PubMed=1563005;
RA   Giaccone, Giuseppe
RA   Battey, James
RA   Gazdar, Adi F.
RA   Oie, Herbert Kazuto
RA   Draoui, Muriel
RA   Moody, Terry W.
RT   "Neuromedin B is present in lung cancer cell lines.";
RL   Cancer Res. 52:2732s-2736s(1992).
//
RX   PubMed=2041050; DOI=10.1093/jnci/83.11.757;
RA   Monks, Anne
RA   Scudiero, Dominic A.
RA   Skehan, Philip
RA   Shoemaker, Robert H.
RA   Paull, Kenneth D.
RA   Vistica, David T.
RA   Hose, Curtis D.
RA   Langley, John
RA   Cronise, Paul
RA   Vaigro-Wolff, Anne
RA   Gray-Goodrich, Marcia
RA   Campbell, Hugh
RA   Mayo, Joseph G.
RA   Boyd, Michael R.
RT   "Feasibility of a high-flux anticancer drug screen using a diverse
RT   panel of cultured human tumor cell lines.";
RL   J. Natl. Cancer Inst. 83:757-766(1991).
//
RX   PubMed=2388294; DOI=10.1093/jnci/82.17.1420;
RA   McLemore, Theodore L.
RA   Litterst, Charles L.
RA   Coudert, Bruno P.
RA   Liu, Mark C.
RA   Hubbard, Walter C.
RA   Adelberg, Steven
RA   Czerwinski, Maciej J.
RA   McMahon, Noreen A.
RA   Eggleston, Joseph C.
RA   Boyd, Michael R.
RT   "Metabolic activation of 4-ipomeanol in human lung, primary pulmonary
RT   carcinomas, and established human pulmonary carcinoma cell lines.";
RL   J. Natl. Cancer Inst. 82:1420-1426(1990).
//
RX   PubMed=3335022;
RA   Alley, Michael C.
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Hursey, Miriam L.
RA   Czerwinski, Maciej J.
RA   Fine, Donald L.
RA   Abbott, Betty Jane
RA   Mayo, Joseph G.
RA   Shoemaker, Robert H.
RA   Boyd, Michael R.
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=3940644;
RA   Brower, Martin
RA   Carney, Desmond Niall
RA   Oie, Herbert Kazuto
RA   Gazdar, Adi F.
RA   Minna, John D.
RT   "Growth of cell lines and clinical specimens of human non-small cell
RT   lung cancer in a serum-free defined medium.";
RL   Cancer Res. 46:798-806(1986).
//
RX   PubMed=7718330; DOI=10.1016/0959-8049(94)00472-H;
RA   Baguley, Bruce Charles
RA   Marshall, Elaine S.
RA   Whittaker, John Richard
RA   Dotchin, M.C.
RA   Nixon, Johanna
RA   McCrystal, Michael R.
RA   Finlay, Graeme John
RA   Matthews, John H.L.
RA   Holdaway, Karen M.
RA   van Zijl, Pierre Leonardus
RT   "Resistance mechanisms determining the in vitro sensitivity to
RT   paclitaxel of tumour cells cultured from patients with ovarian
RT   cancer.";
RL   Eur. J. Cancer 31A:230-237(1995).
//
RX   PubMed=8385084; DOI=10.1111/j.1349-7006.1993.tb02851.x; PMCID=PMC5919128;
RA   Suzuki, Susumu
RA   Takahashi, Takashi
RA   Nakamura, Shigeo
RA   Koike, Koichi
RA   Ariyoshi, Yutaka
RA   Takahashi, Toshitada
RA   Ueda, Ryuzo
RT   "Alterations of integrin expression in human lung cancer.";
RL   Jpn. J. Cancer Res. 84:168-174(1993).
//
RX   PubMed=8626706; DOI=10.1074/jbc.271.19.11477;
RA   Quinn, Kathryn A.
RA   Treston, Anthony M.
RA   Unsworth, Edward J.
RA   Miller, Mae-Jean
RA   Vos, Michele
RA   Grimley, Chris
RA   Battey, James
RA   Mulshine, James L.
RA   Cuttitta, Frank
RT   "Insulin-like growth factor expression in human cancer cell lines.";
RL   J. Biol. Chem. 271:11477-11483(1996).
//
RX   PubMed=8806092; DOI=10.1002/jcb.240630505;
RA   Phelps, Ruby M.
RA   Johnson, Bruce E.
RA   Ihde, Daniel C.
RA   Gazdar, Adi F.
RA   Carbone, David P.
RA   McClintock, Patrick R.
RA   Linnoila, Ritva Ilona
RA   Matthews, Mary J.
RA   Bunn, Paul A. Jr.
RA   Carney, Desmond Niall
RA   Minna, John D.
RA   Mulshine, James L.
RT   "NCI-Navy Medical Oncology Branch cell line data base.";
RL   J. Cell. Biochem. Suppl. 24:32-91(1996).
//
RX   PubMed=9331090;
RA   O'Connor, Patrick M.
RA   Jackman, Joany
RA   Bae, Insoo
RA   Myers, Timothy Gene
RA   Fan, Sai-Jun
RA   Mutoh, Masato
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Sausville, Edward A.
RA   Weinstein, John N.
RA   Friend, Stephen H.
RA   Fornace, Albert J. Jr.
RA   Kohn, Kurt W.
RT   "Characterization of the p53 tumor suppressor pathway in cell lines of
RT   the National Cancer Institute anticancer drug screen and correlations
RT   with the growth-inhibitory potency of 123 anticancer agents.";
RL   Cancer Res. 57:4285-4300(1997).
//
RX   PubMed=10358721; DOI=10.18926/AMO/31626;
RA   Matsushita, Akio
RA   Tabata, Masahiro
RA   Ueoka, Hiroshi
RA   Kiura, Katsuyuki
RA   Shibayama, Takuo
RA   Aoe, Keisuke
RA   Kohara, Hiroyuki
RA   Harada, Mine
RT   "Establishment of a drug sensitivity panel using human lung cancer
RT   cell lines.";
RL   Acta Med. Okayama 53:67-75(1999).
//
RX   PubMed=10700174; DOI=10.1038/73432;
RA   Ross, Douglas T.
RA   Scherf, Uwe
RA   Eisen, Michael Bruce
RA   Perou, Charles M.
RA   Rees, Christian
RA   Spellman, Paul T.
RA   Iyer, Vishwanath R.
RA   Jeffrey, Stefanie S.
RA   van de Rijn, Matt
RA   Waltham, Mark C.
RA   Pergamenschikov, Alexander
RA   Lee, Jeffrey C.F.
RA   Lashkari, Deval
RA   Shalon, Dari
RA   Myers, Timothy Gene
RA   Weinstein, John N.
RA   Botstein, David
RA   Brown, Patrick O'Reilly
RT   "Systematic variation in gene expression patterns in human cancer cell
RT   lines.";
RL   Nat. Genet. 24:227-235(2000).
//
RX   PubMed=11030152; DOI=10.1038/sj.onc.1203815;
RA   Modi, Sanjay
RA   Kubo, Akihito
RA   Oie, Herbert Kazuto
RA   Coxon, Amy B.
RA   Rehmatulla, Ahad
RA   Kaye, Frederic J.
RT   "Protein expression of the RB-related gene family and SV40 large T
RT   antigen in mesothelioma and lung cancer.";
RL   Oncogene 19:4632-4639(2000).
//
RX   PubMed=11551417; DOI=10.1016/S0169-5002(01)00205-7;
RA   Yoon, Sung-Soo
RA   Ahn, Kwang-Sung
RA   Kim, Sun-Hee
RA   Shim, Young Mok
RA   Kim, Jhingook
RT   "In vitro establishment of cis-diammine-dichloroplatinum(II) resistant
RT   lung cancer cell line and modulation of apoptotic gene expression as a
RT   mechanism of resistant phenotype.";
RL   Lung Cancer 33:221-228(2001).
//
RX   PubMed=11583962; DOI=10.1016/S0002-9440(10)62521-7; PMCID=PMC1850523;
RA   Haruki, Nobuhiro
RA   Harano, Tomoko
RA   Masuda, Akira
RA   Kiyono, Tohru
RA   Takahashi, Takao
RA   Tatematsu, Yoshio
RA   Shimizu, Shigeki
RA   Mitsudomi, Tetsuya
RA   Konishi, Hiroyuki
RA   Osada, Hirotaka
RA   Fujii, Yoshitaka
RA   Takahashi, Takashi
RT   "Persistent increase in chromosome instability in lung cancer:
RT   possible indirect involvement of p53 inactivation.";
RL   Am. J. Pathol. 159:1345-1352(2001).
//
RX   PubMed=12068308; DOI=10.1038/nature00766;
RA   Davies, Helen R.
RA   Bignell, Graham Robert
RA   Cox, Charles
RA   Stephens, Philip J.
RA   Edkins, Sarah
RA   Clegg, Sheila
RA   Teague, Jon W.
RA   Woffendin, Hayley
RA   Garnett, Mathew J.
RA   Bottomley, William
RA   Davis, Neil
RA   Dicks, Ed
RA   Ewing, Rebecca
RA   Floyd, Yvonne
RA   Gray, Kristian
RA   Hall, Sarah
RA   Hawes, Rachel
RA   Hughes, Jaime
RA   Kosmidou, Vivian
RA   Menzies, Andrew
RA   Mould, Catherine
RA   Parker, Adrian
RA   Stevens, Claire
RA   Watt, Stephen
RA   Hooper, Steven
RA   Wilson, Rebecca
RA   Jayatilake, Hiran
RA   Gusterson, Barry Austin
RA   Cooper, Colin S.
RA   Shipley, Janet M.
RA   Hargrave, Darren
RA   Pritchard-Jones, Kathy
RA   Maitland, Norman J.
RA   Chenevix-Trench, Georgia
RA   Riggins, Gregory J.
RA   Bigner, Darell Doty
RA   Palmieri, Giuseppe
RA   Cossu, Antonio
RA   Flanagan, Adrienne M.
RA   Nicholson, Andrew
RA   Ho, Judy W.C.
RA   Leung, Suet Yi
RA   Yuen, Siu Tsan
RA   Weber, Barbara L.
RA   Seigler, Hilliard Foster
RA   Darrow, Timothy L.
RA   Paterson, Hugh F.
RA   Marais, Richard
RA   Marshall, Christopher John
RA   Wooster, Richard
RA   Stratton, Michael Rudolf
RA   Futreal, P. Andrew
RT   "Mutations of the BRAF gene in human cancer.";
RL   Nature 417:949-954(2002).
//
RX   PubMed=12794755; DOI=10.1002/ijc.11184;
RA   Endoh, Hideki
RA   Yatabe, Yasushi
RA   Shimizu, Shigeki
RA   Tajima, Kohei
RA   Kuwano, Hiroyuki
RA   Takahashi, Takashi
RA   Mitsudomi, Tetsuya
RT   "RASSF1A gene inactivation in non-small cell lung cancer and its
RT   clinical implication.";
RL   Int. J. Cancer 106:45-51(2003).
//
RX   PubMed=15746151; DOI=10.1093/hmg/ddi092;
RA   Izumi, Hiroto
RA   Inoue, Jun
RA   Yokoi, Sana
RA   Hosoda, Hiroshi
RA   Shibata, Tatsuhiro
RA   Sunamori, Makoto
RA   Hirohashi, Setsuo
RA   Inazawa, Johji
RA   Imoto, Issei
RT   "Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in
RT   non-small cell lung cancers.";
RL   Hum. Mol. Genet. 14:997-1007(2005).
//
RX   PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742;
RA   Adams, Sharon
RA   Robbins, Fu-Meei
RA   Chen, Deborah
RA   Wagage, Devika
RA   Holbeck, Susan L.
RA   Morse, Herbert Carpenter 3rd
RA   Stroncek, David
RA   Marincola, Francesco M.
RT   "HLA class I and II genotype of the NCI-60 cell lines.";
RL   J. Transl. Med. 3:11.1-11.8(2005).
//
RX   PubMed=15900046; DOI=10.1093/jnci/dji133;
RA   Mashima, Tetsuo
RA   Oh-hara, Tomoko
RA   Sato, Shigeo
RA   Mochizuki, Mikiko
RA   Sugimoto, Yoshikazu
RA   Yamazaki, Kanami
RA   Hamada, Jun-ichi
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RX   PubMed=17332333; DOI=10.1158/0008-5472.CAN-06-3339;
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RT   "Differential constitutive activation of the epidermal growth factor
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RX   PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846;
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RX   PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022;
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RT   "JFCR39, a panel of 39 human cancer cell lines, and its application in
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RT   "High resolution copy number variation data in the NCI-60 cancer cell
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RA   Bagni, Rachel
RA   Yi, Ming
RA   Afghani, Shervin
RA   Burgan, William
RA   Fer, Nicole
RA   Strathern, Leslie A.
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RA   Smith, Brian
RA   Waters, Andrew Michael
RA   Drubin, David Alan
RA   Thomson, Ty
RA   Liao, Rosy
RA   Greninger, Patricia
RA   Stein, Giovanna T.
RA   Murchie, Ellen
RA   Cortez, Eliane
RA   Egan, Regina K.
RA   Procter, Lauren
RA   Bess, Matthew
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RA   Lee, Chih-Shia
RA   Lee, Liam Changwoo
RA   Fellmann, Christof
RA   Stephens, Robert
RA   Luo, Ji
RA   Lowe, Scott William
RA   Benes, Cyril Henri
RA   McCormick, Frank
RT   "Differential effector engagement by oncogenic KRAS.";
RL   Cell Rep. 22:1889-1902(2018).
//
RX   PubMed=29681454; DOI=10.1016/j.cell.2018.03.028; PMCID=PMC5935540;
RA   McMillan, Elizabeth A.
RA   Ryu, Myung-Jeom
RA   Diep, Caroline H.
RA   Mendiratta, Saurabh
RA   Clemenceau, Jean Rene
RA   Vaden, Rachel M.
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RA   Motoyaji, Takashi
RA   Covington, Kyle R.
RA   Peyton, Michael
RA   Huffman, Kenneth
RA   Wu, Xiao-Feng
RA   Girard, Luc
RA   Sung, Yeojin
RA   Chen, Pei-Hsaun
RA   Mallipeddi, Prema Latha
RA   Lee, Joo Young
RA   Hanson, Jordan
RA   Voruganti, Sukesh
RA   Yu, Yunku
RA   Park, Sunho
RA   Sudderth, Jessica
RA   DeSevo, Christopher
RA   Muzny, Donna M.
RA   Doddapaneni, HarshaVardhan
RA   Gazdar, Adi F.
RA   Gibbs, Richard Alexander
RA   Hwang, Tae Hyun
RA   Heymach, John Victor
RA   Wistuba, Ignacio Ivan
RA   Coombes, Kevin Robert
RA   Williams, Noelle S.
RA   Wheeler, David A.
RA   MacMillan, John B.
RA   DeBerardinis, Ralph J.
RA   Roth, Michael G.
RA   Posner, Bruce Arthur
RA   Minna, John D.
RA   Kim, Hyun Seok
RA   White, Michael A.
RT   "Chemistry-first approach for nomination of personalized treatment in
RT   lung cancer.";
RL   Cell 173:864-878.e29(2018).
//
RX   PubMed=30038707; DOI=10.18632/oncotarget.25642; PMCID=PMC6049873;
RA   Du, Li-Qin
RA   Zhao, Zhen-Ze
RA   Suraokar, Milind Bhalchandra
RA   Shelton, Spencer S.
RA   Ma, Xiu-Ye
RA   Hsiao, Tzu-Hung
RA   Minna, John D.
RA   Wistuba, Ignacio Ivan
RA   Pertsemlidis, Alexander
RT   "LMO1 functions as an oncogene by regulating TTK expression and
RT   correlates with neuroendocrine differentiation of lung cancer.";
RL   Oncotarget 9:29601-29618(2018).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
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RA   Hess, Julian M.
RA   Haas, Brian J.
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RA   Weir, Barbara A.
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RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
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RA   Shih, Juliann
RA   Hadi, Kevin
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RA   Bistline, Jonathan
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RA   Reddy, Anupama
RA   Sonkin, Dmitriy
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RA   Korn, Joshua M.
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RA   Jones, Michael D.
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RA   Caponigro, Giordano
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RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
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RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
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RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
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RA   Mills, Gordon B.
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RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084;
RA   Mulshine, James L.
RA   Ujhazy, Peter
RA   Antman, Melissa
RA   Burgess, Christine M.
RA   Kuzmin, Igor A.
RA   Bunn, Paul A. Jr.
RA   Johnson, Bruce E.
RA   Roth, Jack Alan
RA   Pass, Harvey I.
RA   Ross, Sheila M.
RA   Aldige, Carolyn R.
RA   Wistuba, Ignacio Ivan
RA   Minna, John D.
RT   "From clinical specimens to human cancer preclinical models -- a journey
RT   the NCI-cell line database-25 years later.";
RL   J. Cell. Biochem. 121:3986-3999(2020).
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254;
RA   Nusinow, David Paul
RA   Szpyt, John
RA   Ghandi, Mahmoud
RA   Rose, Christopher M.
RA   McDonald, E. Robert 3rd
RA   Kalocsay, Marian
RA   Jane-Valbuena, Judit
RA   Gelfand, Ellen T.
RA   Schweppe, Devin K.
RA   Jedrychowski, Mark P.
RA   Golji, Javad
RA   Porter, Dale A.
RA   Rejtar, Tomas
RA   Wang, Y. Karen
RA   Kryukov, Gregory V.
RA   Stegmeier, Frank
RA   Erickson, Brian K.
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RA   Gygi, Steven P.
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
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RX   PubMed=33425914; DOI=10.3389/fcell.2020.607275; PMCID=PMC7786180;
RA   Lei, Zi-Ning
RA   Teng, Qiu-Xu
RA   Zhang, Wei
RA   Fan, Ying-Fang
RA   Wang, Jing-Quan
RA   Cai, Chao-Yun
RA   Lu, Kimberly W.
RA   Yang, Dong-Hua
RA   Wurpel, John N.D.
RA   Chen, Zhe-Sheng
RT   "Establishment and characterization of a topotecan resistant non-small
RT   cell lung cancer NCI-H460/TPT10 cell line.";
RL   Front. Cell Dev. Biol. 8:607275.1-607275.10(2020).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//
RX   PubMed=38861359; DOI=10.1158/0008-5472.CAN-23-3031; PMCID=PMC11292194;
RA   Kunkel, Mark W.
RA   Coussens, Nathan P.
RA   Morris, Joel
RA   Taylor, Ronald C.
RA   Dexheimer, Thomas S.
RA   Jones, Eric M.
RA   Doroshow, James H.
RA   Teicher, Beverly A.
RT   "HTS384 NCI60: the next phase of the NCI60 screen.";
RL   Cancer Res. 84:2403-2416(2024).
//