ID   NBT-II
AC   CVCL_0453
SY   Nara Bladder Tumor No. 2; Nara Bladder Tumor II; NBTII
DR   BTO; BTO_0004316
DR   CLO; CLO_0007950
DR   MCCL; MCC:0000351
DR   CLDB; cl3646
DR   ATCC; CRL-1655
DR   ECACC; 93012901
DR   KCLB; 21655
DR   Wikidata; Q54907562
RX   PubMed=639055;
RX   PubMed=3567912;
RX   PubMed=4941696;
RX   PubMed=6480288;
RX   PubMed=9369930;
RX   PubMed=29732388;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-146.html
CC   Transformant: ChEBI; CHEBI_91275; N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN).
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
CC   Breed/subspecies: Wistar; RS=RS_0000955.
DI   NCIt; C60691; Rat urinary system neoplasms
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 19
CH   CVCL_M906 ! M-NBT-II
CH   CVCL_4671 ! NBT-L1
CH   CVCL_4672 ! NBT-L2a
CH   CVCL_4673 ! NBT-L2b
CH   CVCL_4674 ! NBT-T1
CH   CVCL_4675 ! NBT-T2
//
RX   PubMed=639055;
RA   Geisinger, Kim R.
RA   Leighton, Joseph
RA   Zealberg, Joseph
RT   "Appearance of giant cells as a morphological response of rat bladder
RT   carcinoma cell line (Nara Bladder Tumor No. 2) to a continuous thermal
RT   gradient in tissue culture.";
RL   Cancer Res. 38:1223-1230(1978).
//
RX   PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350;
RA   Zuiverloon, Tahlita C.M.
RA   de Jong, Florus C.
RA   Costello, James C.
RA   Theodorescu, Dan
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).
//
RX   PubMed=3567912;
RA   Rowley, David R.
RA   Tindall, Donald J.
RT   "Responses of NBT-II bladder carcinoma cells to conditioned medium
RT   from normal fetal urogenital sinus.";
RL   Cancer Res. 47:2955-2960(1987).
//
RX   PubMed=9369930; DOI=10.1111/j.1349-7006.1997.tb00458.x; PMCID=PMC5921519;
RA   Nishi, Nozomu
RA   Inui, Masashi
RA   Kishi, Yukiko
RA   Miyanaka, Hiroshi
RA   Wada, Fumio
RT   "Isolation and characterization of invasive and noninvasive variants
RT   of a rat bladder tumor cell line.";
RL   Jpn. J. Cancer Res. 88:831-838(1997).
//
RX   PubMed=6480288;
RA   Schroyens, Wilfried
RA   Bruyneel, Remy
RA   Tchao, Ruy
RA   Leighton, Joseph
RA   Dragonetti, Christian H.
RA   Mareel, Marc M.
RT   "Comparison of invasiveness and non-invasiveness of two epithelial
RT   cell lines in vitro.";
RL   Invasion Metastasis 4:160-170(1984).
//
RX   PubMed=4941696; DOI=10.1093/jnci/47.5.979;
RA   Toyoshima, Keiji
RA   Ito, Nobuyuki
RA   Hiasa, Yoshio
RA   Kamamoto, Yoshiyuki
RA   Makiura, Sachio
RT   "Tissue culture of urinary bladder tumor induced in a rat by
RT   N-butyl-N-(-4-hydroxybutyl)nitrosamine: establishment of cell line,
RT   Nara Bladder Tumor II.";
RL   J. Natl. Cancer Inst. 47:979-985(1971).
//