ID ML-1 [Human leukemia] AC CVCL_0436 SY ML1 DR BTO; BTO_0001884 DR CLO; CLO_0007735 DR EFO; EFO_0022439 DR MCCL; MCC:0000331 DR CLDB; cl3489 DR Cell_Model_Passport; SIDM00440 DR Cosmic; 787453 DR Cosmic; 798669 DR Cosmic; 919125 DR Cosmic; 924048 DR Cosmic; 947369 DR Cosmic; 994171 DR Cosmic; 998746 DR Cosmic; 999727 DR Cosmic; 1037658 DR Cosmic; 1078735 DR Cosmic; 1078738 DR Cosmic; 1127255 DR Cosmic; 2089662 DR Cosmic; 2301563 DR ECACC; 88113007 DR Wikidata; Q54905840 RX DOI=10.1016/B978-0-12-221970-2.50457-5; RX PubMed=1571549; RX PubMed=3458526; RX PubMed=6091813; RX PubMed=7798274; RX PubMed=8814454; RX PubMed=9510473; RX PubMed=10739008; RX PubMed=11226526; RX PubMed=21552520; RX PubMed=23955599; CC Population: Caucasian. CC Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526). CC Omics: Proteomics; PTM; Phosphorylation; Quantitative. CC Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. ST Source(s): COG; ECACC=88113007 ST Amelogenin: X ST CSF1PO: 10,11 ST D13S317: 9,12 ST D16S539: 9,12 ST D18S51: 14,18 ST D19S433: 14 ST D21S11: 29 ST D2S1338: 16,17 ST D3S1358: 15 ST D5S818: 12 ST D7S820: 9,11 ST D8S1179: 8,13 ST FGA: 23,25 ST TH01: 7,9.3 ST TPOX: 8,10 ST vWA: 16 DI NCIt; C9154; Adult acute myeloid leukemia DI ORDO; Orphanet_519; Acute myeloid leukemia OX NCBI_TaxID=9606; ! Homo sapiens (Human) OI CVCL_1418 ! ML-2 OI CVCL_H526 ! ML-3 SX Male AG 26Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 25 // RX PubMed=8814454; DOI=10.1002/(SICI)1098-2264(199607)16:3<204::AID-GCC8>3.0.CO;2-2; RA Strout, Matthew P. RA Mrozek, Krzysztof RA Heinonen, Kristiina RA Sait, Sheila N. Jani RA Shows, Thomas Byron RA Aplan, Peter D. RT "ML-1 cell line lacks a germline MLL locus."; RL Genes Chromosomes Cancer 16:204-210(1996). // RX PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x; PMCID=PMC5921588; RA Hosoya, Noriko RA Hangaishi, Akira RA Ogawa, Seishi RA Miyagawa, Kiyoshi RA Mitani, Kinuko RA Yazaki, Yoshio RA Hirai, Hisamaru RT "Frameshift mutations of the hMSH6 gene in human leukemia cell RT lines."; RL Jpn. J. Cancer Res. 89:33-39(1998). // RX PubMed=21552520; DOI=10.1371/journal.pone.0019169; PMCID=PMC3084268; RA Gu, Ting-Lei RA Nardone, Julie RA Wang, Yi RA Loriaux, Marc RA Villen, Judit RA Beausoleil, Sean A. RA Tucker, Meghan RA Kornhauser, Jon M. RA Ren, Jian-Min RA MacNeill, Joan RA Gygi, Steven P. RA Druker, Brian Jay RA Heinrich, Michael Charles RA Rush, John RA Polakiewicz, Roberto D. RT "Survey of activated FLT3 signaling in leukemia."; RL PLoS ONE 6:e19169.1-e19169.10(2011). // RX PubMed=1571549; DOI=10.1182/blood.V79.9.2378.2378; RA Sugimoto, Koichi RA Toyoshima, Hideo RA Sakai, Ryuichi RA Miyagawa, Kiyoshi RA Hagiwara, Koichi RA Ishikawa, Fuyuki RA Takaku, Fumimaro RA Yazaki, Yoshio RA Hirai, Hisamaru RT "Frequent mutations in the p53 gene in human myeloid leukemia cell RT lines."; RL Blood 79:2378-2383(1992). // RX PubMed=23955599; DOI=10.1038/ng.2731; RA Kon, Ayana RA Shih, Lee-Yung RA Minamino, Masashi RA Sanada, Masashi RA Shiraishi, Yuichi RA Nagata, Yasunobu RA Yoshida, Ken-ichi RA Okuno, Yusuke RA Bando, Masashige RA Nakato, Ryuichiro RA Ishikawa, Shumpei RA Sato-Otsubo, Aiko RA Nagae, Genta RA Nishimoto, Aiko RA Haferlach, Claudia RA Nowak, Daniel RA Sato, Yusuke RA Alpermann, Tamara RA Nagasaki, Masao RA Shimamura, Teppei RA Tanaka, Hiroko RA Chiba, Kenichi RA Yamamoto, Ryo RA Yamaguchi, Tomoyuki RA Otsu, Makoto RA Obara, Naoshi RA Sakata-Yanagimoto, Mamiko RA Nakamaki, Tsuyoshi RA Ishiyama, Ken RA Nolte, Florian RA Hofmann, Wolf-Karsten RA Miyawaki, Shuichi RA Chiba, Shigeru RA Mori, Hiraku RA Nakauchi, Hiromitsu RA Koeffler, Harold Phillip RA Aburatani, Hiroyuki RA Haferlach, Torsten RA Shirahige, Katsuhiko RA Miyano, Satoru RA Ogawa, Seishi RT "Recurrent mutations in multiple components of the cohesin complex in RT myeloid neoplasms."; RL Nat. Genet. 45:1232-1237(2013). // RX PubMed=7798274; DOI=10.1016/S0021-9258(18)31687-9; RA Carrier, France RA Smith, Martin L. RA Bae, Insoo RA Kilpatrick, Katherine E. RA Lansing, Timothy J. RA Chen, Chaw-Yuan RA Engelstein, Marcy RA Friend, Stephen H. RA Henner, W. David RA Gilmer, Tona Morgan RA Kastan, Michael Barry RA Fornace, Albert J. Jr. RT "Characterization of human Gadd45, a p53-regulated protein."; RL J. Biol. Chem. 269:32672-32677(1994). // RX PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4; RA Inoue, Kaoru RA Kohno, Takashi RA Takakura, Satoshi RA Hayashi, Yasuhide RA Mizoguchi, Hideaki RA Yokota, Jun RT "Frequent microsatellite instability and BAX mutations in T cell acute RT lymphoblastic leukemia cell lines."; RL Leuk. Res. 24:255-262(2000). // RX PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1; RA Inoue, Kaoru RA Kohno, Takashi RA Takakura, Satoshi RA Hayashi, Yasuhide RA Mizoguchi, Hideaki RA Yokota, Jun RT "Corrigendum to 'Frequent microsatellite instability and BAX mutations RT in T cell acute lymphoblastic leukemia cell lines' Leukemia Research 24 RT (2000), 255-262."; RL Leuk. Res. 25:275-278(2001). // RX PubMed=3458526; RA Ohyashiki, Kazuma RA Ohyashiki, Junko H. RA Sandberg, Avery Aba RT "Cytogenetic characterization of putative human myeloblastic leukemia RT cell lines (ML-1, -2, and -3): origin of the cells."; RL Cancer Res. 46:3642-3647(1986). // RX PubMed=6091813; DOI=10.1182/blood.V64.5.1059.1059; RA Palumbo, Antonio RA Minowada, Jun RA Erikson, Jan RA Croce, Carlo Maria RA Rovera, Giovanni RT "Lineage infidelity of a human myelogenous leukemia cell line."; RL Blood 64:1059-1063(1984). // RX DOI=10.1016/B978-0-12-221970-2.50457-5; RA Drexler, Hans Gunther RT "The leukemia-lymphoma cell line factsbook."; RL (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001). //