ID MKN45 AC CVCL_0434 SY MKN-45; MKN 45 DR BTO; BTO_0001225 DR CLO; CLO_0007733 DR CLO; CLO_0050797 DR EFO; EFO_0002832 DR MCCL; MCC:0000329 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR BioGRID_ORCS_Cell_line; 404 DR BioSample; SAMN03473237 DR BioSample; SAMN03473585 DR BioSample; SAMN10988555 DR cancercelllines; CVCL_0434 DR CCRID; 1101HUM-PUMC000229 DR CCTCC; GDC0220 DR Cell_Model_Passport; SIDM00247 DR CGH-DB; 120-1 DR CGH-DB; 9022-4 DR ChEMBL-Cells; CHEMBL3307603 DR ChEMBL-Targets; CHEMBL614354 DR CLS; 300489 DR Cosmic; 685596 DR Cosmic; 801339 DR Cosmic; 848147 DR Cosmic; 848373 DR Cosmic; 873711 DR Cosmic; 877042 DR Cosmic; 887256 DR Cosmic; 888827 DR Cosmic; 897535 DR Cosmic; 918497 DR Cosmic; 922696 DR Cosmic; 925340 DR Cosmic; 926114 DR Cosmic; 968349 DR Cosmic; 983727 DR Cosmic; 1001651 DR Cosmic; 1001655 DR Cosmic; 1007602 DR Cosmic; 1090461 DR Cosmic; 1093299 DR Cosmic; 1187283 DR Cosmic; 1223589 DR Cosmic; 1329185 DR Cosmic; 1436026 DR Cosmic; 1460707 DR Cosmic; 1518241 DR Cosmic; 1518255 DR Cosmic; 1582430 DR Cosmic; 1627265 DR Cosmic; 1995510 DR Cosmic; 2036663 DR Cosmic; 2807633 DR Cosmic; 2823225 DR Cosmic-CLP; 925340 DR DepMap; ACH-000356 DR DSMZ; ACC-409 DR DSMZCellDive; ACC-409 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR FANTOM5_SSTAR; 10612-108F9 DR GDSC; 925340 DR GEO; GSM552364 DR GEO; GSM562395 DR GEO; GSM618013 DR GEO; GSM618014 DR GEO; GSM618015 DR GEO; GSM618016 DR GEO; GSM827532 DR GEO; GSM828836 DR GEO; GSM844607 DR GEO; GSM887324 DR GEO; GSM888400 DR GEO; GSM1374681 DR GEO; GSM1670113 DR IARC_TP53; 21633 DR IARC_TP53; 30213 DR IBRC; C10137 DR JCRB; JCRB0254 DR KCLB; 80103 DR LiGeA; CCLE_725 DR LINCS_LDP; LCL-1535 DR NCBI_Iran; C615 DR PharmacoDB; MKN45_938_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_0434 DR PubChem_Cell_line; CVCL_0434 DR RCB; RCB1001 DR Wikidata; Q28473066 RX CelloPub=CLPUB00581; RX CelloPub=CLPUB00584; RX DOI=10.1016/B978-0-12-333530-2.50014-9; RX DOI=10.1016/j.procbio.2020.01.033; RX PubMed=758928; RX PubMed=1370612; RX PubMed=1486568; RX PubMed=1778766; RX PubMed=1846553; RX PubMed=1933850; RX PubMed=2061947; RX PubMed=2105279; RX PubMed=3962675; RX PubMed=3986962; RX PubMed=6862145; RX PubMed=9023415; RX PubMed=9247707; RX PubMed=9290701; RX PubMed=9665481; RX PubMed=11107048; RX PubMed=11314020; RX PubMed=11668190; RX PubMed=15723654; RX PubMed=15767549; RX PubMed=15900046; RX PubMed=15901131; RX PubMed=18804159; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=22336246; RX PubMed=22460905; RX PubMed=22531121; RX PubMed=23671654; RX PubMed=24587255; RX PubMed=24807215; RX PubMed=25343454; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25960936; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=29435981; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-496.html WW Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/gastric-xenograft-model/mkn-45-xenograft-model/ CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: JFCR39 cancer cell line panel. CC Part of: JFCR45 cancer cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Population: Japanese. CC Characteristics: MET-amplified, contains 12-13 copies of the gene (PubMed=29435981). CC Doubling time: 30-33 hours (PubMed=3962675); 33 hours (PubMed=29435981); 30-38 hours (CelloPub=CLPUB00584); 16 hours (PubMed=2105279); ~60 hours (DSMZ=ACC-409). CC HLA typing: A*24:02,24:02; B*52:01; C*12:02,12:02 (PubMed=25960936). CC HLA typing: A*24:02,24:02; B*52:01,67:02; C*12:02,12:02 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (PubMed=23671654; Sanger). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (Cosmic-CLP=925340; DepMap=ACH-000356). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=1.54%; Native American=0%; East Asian, North=85.37%; East Asian, South=9.42%; South Asian=0%; European, North=0%; European, South=3.67% (PubMed=30894373). CC Caution: Was indicated not to have a TP53 mutation in PubMed=1370612 and PubMed=15900046. CC Misspelling: MKN46; Cosmic=968349. CC Misspelling: MNK-45; Note=Occasionally. CC Misspelling: MNK45; Note=Occasionally. CC Misspelling: NKM-45; Note=Occasionally. CC Misspelling: NKM45; Note=Occasionally. CC Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. ST Source(s): CCRID=1101HUM-PUMC000229; CLS=300489; Cosmic-CLP=925340; DSMZ=ACC-409; JCRB=JCRB0254; KCLB=80103; PubMed=25877200; RCB=RCB1001 ST Amelogenin: X ST CSF1PO: 12 ST D12S391: 26 ST D13S317: 8,11 ST D16S539: 10 ST D18S51: 16 ST D19S433: 14,16.2 (CCRID=1101HUM-PUMC000229; CLS=300489) ST D19S433: 14,17 (DSMZ=ACC-409) ST D21S11: 31 ST D2S1338: 18 ST D3S1358: 15,16 ST D5S818: 10,11 ST D6S1043: 14 ST D7S820: 10,11 ST D8S1179: 13,17 ST FGA: 19 (KCLB=80103) ST FGA: 19,24 (CCRID=1101HUM-PUMC000229; CLS=300489; DSMZ=ACC-409; PubMed=25877200) ST Penta D: 10 ST Penta E: 10 ST TH01: 7 ST TPOX: 8 ST vWA: 19 DI NCIt; C4004; Gastric adenocarcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 62Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 49 CH CVCL_7668 ! GTL-16 CH CVCL_F1RY ! HyCyte MKN45 KO-hEDAR CH CVCL_E1M7 ! HyCyte MKN45 KO-hSORCS2 CH CVCL_E3I1 ! HyCyte MKN45-Luc CH CVCL_XE84 ! MKN45-Cas9-526 CH CVCL_UW57 ! MKN45-EGFP CH CVCL_J262 ! MKN45-Luc CH CVCL_YX96 ! MKN45/CDDP/R1 CH CVCL_E2W7 ! MKN45/CV CH CVCL_A9J7 ! MKN45/DR CH CVCL_QY39 ! MKN45/F2R CH CVCL_9645 ! MKN45/TP CH CVCL_D5HU ! MKN45cl85 CH CVCL_RM02 ! MKN45G CH CVCL_Y476 ! MKN45P CH CVCL_Z941 ! MKN45R0.05 CH CVCL_Z942 ! MKN45R0.08 // RX PubMed=24807215; DOI=10.1038/ncomms4830; PMCID=PMC4024760; RA Liu, Jin-Feng RA McCleland, Mark L. RA Stawiski, Eric W. RA Gnad, Florian RA Mayba, Oleg RA Haverty, Peter M. RA Durinck, Steffen RA Chen, Ying-Jiun RA Klijn, Christiaan RA Jhunjhunwala, Suchit RA Lawrence, Michael RA Liu, Han-Bin RA Wan, Yi-Nan RA Chopra, Vivek S. RA Yaylaoglu, Murat Burat RA Yuan, Wen-Lin RA Ha, Connie RA Gilbert, Houston N. RA Reeder, Jens RA Pau, Gregoire RA Stinson, Jeremy RA Stern, Howard M. RA Manning, Gerard RA Wu, Thomas D. RA Neve, Richard M. RA de Sauvage, Frederic J. RA Modrusan, Zora RA Seshagiri, Somasekar RA Firestein, Ron RA Zhang, Ze-Min RT "Integrated exome and transcriptome sequencing reveals ZAK isoform RT usage in gastric cancer."; RL Nat. Commun. 5:3830.1-3830.8(2014). // RX PubMed=2105279; DOI=10.1002/ijc.2910450117; RA Watson, Susan A. RA Durrant, Lindy G. RA Morris, David Lawson RT "The effect of the E2 prostaglandin enprostil, and the somatostatin RT analogue SMS 201 995, on the growth of a human gastric cell line, RT MKN45G."; RL Int. J. Cancer 45:90-94(1990). // RX PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0; RA Matozaki, Takashi RA Sakamoto, Choitsu RA Matsuda, Kohei RA Suzuki, Toshiya RA Konda, Yoshitaka RA Nakano, Osamu RA Wada, Ken RA Uchida, Tohru RA Nishisaki, Hogara RA Nagao, Munehiko RA Kasuga, Masato RT "Missense mutations and a deletion of the p53 gene in human gastric RT cancer."; RL Biochem. Biophys. Res. Commun. 182:215-223(1992). // RX PubMed=11107048; DOI=10.1046/j.1440-1827.2000.01117.x; RA Yokozaki, Hiroshi RT "Molecular characteristics of eight gastric cancer cell lines RT established in Japan."; RL Pathol. Int. 50:767-777(2000). // RX PubMed=11668190; DOI=10.1177/002215540104901105; RA Quentmeier, Hilmar RA Osborn, Mary RA Reinhardt, Julia RA Zaborski, Margarete RA Drexler, Hans Gunther RT "Immunocytochemical analysis of cell lines derived from solid RT tumors."; RL J. Histochem. Cytochem. 49:1369-1378(2001). // RX PubMed=24587255; DOI=10.1371/journal.pone.0090155; PMCID=PMC3937424; RA Endo, Fumitaka RA Nishizuka, Satoshi S. RA Kume, Kohei RA Ishida, Kazushige RA Katagiri, Hirokatsu RA Ishida, Kaoru RA Sato, Kei RA Iwaya, Takeshi RA Koeda, Keisuke RA Wakabayashi, Go RT "A compensatory role of NF-kappaB to p53 in response to 5-FU-based RT chemotherapy for gastric cancer cell lines."; RL PLoS ONE 9:e90155.1-e90155.8(2014). // RX DOI=10.1016/B978-0-12-333530-2.50014-9; RA Sekiguchi, Morimasa RA Suzuki, Toshimitsu RT "Gastric tumor cell lines."; RL (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.287-316; Academic Press; New York; USA (1994). // RX PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017; RA Kong, De-Xin RA Yamori, Takao RT "JFCR39, a panel of 39 human cancer cell lines, and its application in RT the discovery and development of anticancer drugs."; RL Bioorg. Med. Chem. 20:1947-1951(2012). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=3962675; DOI=10.1111/j.1440-1827.1986.tb01461.x; RA Motoyama, Teiichi RA Hojo, Haruto RA Watanabe, Hidenobu RT "Comparison of seven cell lines derived from human gastric RT carcinomas."; RL Acta Pathol. Jpn. 36:65-83(1986). // RX PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234; RA Nakatsu, Noriyuki RA Yoshida, Yoko RA Yamazaki, Kanami RA Nakamura, Tomoki RA Dan, Shingo RA Fukui, Yasuhisa RA Yamori, Takao RT "Chemosensitivity profile of cancer cell lines and identification of RT genes determining chemosensitivity by an integrated bioinformatical RT approach using cDNA arrays."; RL Mol. Cancer Ther. 4:399-412(2005). // RX PubMed=1486568; DOI=10.1016/0165-4608(92)90350-H; RA Rege-Cambrin, Giovanna RA Scaravaglio, Patrizia RA Carozzi, Franca RA Giordano, Silvia RA Ponzetto, Carola RA Comoglio, Paolo Maria RA Saglio, Giuseppe RT "Karyotypic analysis of gastric carcinoma cell lines carrying an RT amplified c-met oncogene."; RL Cancer Genet. Cytogenet. 64:170-173(1992). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D; RA Jia, Li-Qun RA Osada, Motonobu RA Ishioka, Chikashi RA Gamo, Makio RA Ikawa, Shuntaro RA Suzuki, Takao RA Shimodaira, Hideki RA Niitani, Tomohito RA Kudo, Toshio RA Akiyama, Mitoshi RA Kimura, Narimiti RA Matsuo, Mitsuyoshi RA Mizusawa, Hiroshi RA Tanaka, Noriho RA Koyama, Hideki RA Namba, Masayoshi RA Kanamaru, Ryunosuke RA Kuroki, Toshio RT "Screening the p53 status of human cell lines using a yeast functional RT assay."; RL Mol. Carcinog. 19:243-253(1997). // RX PubMed=23671654; DOI=10.1371/journal.pone.0063056; PMCID=PMC3646030; RA Lu, Yu-Heng RA Soong, T. David RA Elemento, Olivier RT "A novel approach for characterizing microsatellite instability in RT cancer cells."; RL PLoS ONE 8:e63056.1-e63056.10(2013). // RX PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x; PMCID=PMC11160020; RA Takada, Hisashi RA Imoto, Issei RA Tsuda, Hitoshi RA Sonoda, Itaru RA Ichikura, Takashi RA Mochizuki, Hidetaka RA Okanoue, Takeshi RA Inazawa, Johji RT "Screening of DNA copy-number aberrations in gastric cancer cell lines RT by array-based comparative genomic hybridization."; RL Cancer Sci. 96:100-110(2005). // RX PubMed=15900046; DOI=10.1093/jnci/dji133; RA Mashima, Tetsuo RA Oh-hara, Tomoko RA Sato, Shigeo RA Mochizuki, Mikiko RA Sugimoto, Yoshikazu RA Yamazaki, Kanami RA Hamada, Jun-ichi RA Tada, Mitsuhiro RA Moriuchi, Tetsuya RA Ishikawa, Yuichi RA Kato, Yo RA Tomoda, Hiroshi RA Yamori, Takao RA Tsuruo, Takashi RT "p53-defective tumors with a functional apoptosome-mediated pathway: a RT new therapeutic target."; RL J. Natl. Cancer Inst. 97:765-777(2005). // RX PubMed=6862145; DOI=10.20772/cancersci1959.74.2_240; RA Naito, Seiji RA Inoue, Sadami RA Kinjo, Mitsuru RA Tanaka, Kenzo RT "Thromboplastic and fibrinolytic activities of cultured human gastric RT cancer cell lines."; RL Gann 74:240-247(1983). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=1778766; DOI=10.1111/j.1349-7006.1991.tb01816.x; PMCID=PMC5918361; RA Takeshima, Eisuke RA Hamaguchi, Michinari RA Watanabe, Tadashi RA Akiyama, Seiji RA Kataoka, Masato RA Ohnishi, Yukano RA Xiao, Heng-Yi RA Nagai, Yoshiyuki RA Takagi, Hiroshi RT "Aberrant elevation of tyrosine-specific phosphorylation in human RT gastric cancer cells."; RL Jpn. J. Cancer Res. 82:1428-1435(1991). // RX PubMed=758928; DOI=10.1038/bjc.1979.3; PMCID=PMC2009802; RA Kinjo, Mitsuru RA Oka, Kazunari RA Naito, Seiji RA Kohga, Shin RA Tanaka, Kenzo RA Oboshi, Shoichi RA Hayata, Yoshihiro RA Yasumoto, Kosei RT "Thromboplastic and fibrinolytic activities of cultured human cancer RT cell lines."; RL Br. J. Cancer 39:15-23(1979). // RX PubMed=15901131; DOI=10.1016/j.prp.2005.01.002; RA Murai, Yoshihiro RA Hayashi, Shinichi RA Takahashi, Hiroyuki RA Tsuneyama, Koichi RA Takano, Yasuo RT "Correlation between DNA alterations and p53 and p16 protein RT expression in cancer cell lines."; RL Pathol. Res. Pract. 201:109-115(2005). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX CelloPub=CLPUB00584; RA Motoyama, Teiichi RA Hojo, Haruto RA Suzuki, Toshimitsu RA Oboshi, Shoichi RT "Evaluation of the regrowth assay method as an in vitro drug sensitivity RT test and its application to cultured human gastric cancer cell lines."; RL Acta Med. Biol. 27:49-63(1979). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=29435981; DOI=10.1002/ijc.31304; RA Kim, Hyun Jeong RA Kang, Sun Kyoung RA Kwon, Woo Sun RA Kim, Tae Soo RA Jeong, Inhye RA Jeung, Hei-Cheul RA Kragh, Michael RA Horak, Ivan D. RA Chung, Hyun Cheol RA Rha, Sun Young RT "Forty-nine gastric cancer cell lines with integrative genomic RT profiling for development of c-MET inhibitor."; RL Int. J. Cancer 143:151-159(2018). // RX PubMed=22531121; DOI=10.2739/kurumemedj.58.73; RA Koga, Atsuhiko RA Aoyagi, Keishiro RA Imaizumi, Takuya RA Miyagi, Motoshi RA Shirouzu, Kazuo RT "Comparison between the gastric cancer cell line MKN-45 and the RT high-potential peritoneal dissemination gastric cancer cell line RT MKN-45P."; RL Kurume Med. J. 58:73-79(2011). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=11314020; DOI=10.1038/sj.onc.1204160; RA Kataoka, Hiromi RA Miura, Yutaka RA Joh, Takashi RA Seno, Kyoji RA Tada, Toyohiro RA Tamaoki, Taiki RA Nakabayashi, Hidekazu RA Kawaguchi, Makoto RA Asai, Kiyofumi RA Kato, Taiji RA Itoh, Makoto RT "Alpha-fetoprotein producing gastric cancer lacks transcription factor RT ATBF1."; RL Oncogene 20:869-873(2001). // RX PubMed=9665481; DOI=10.1016/S0002-9440(10)65561-7; PMCID=PMC1852940; RA Paciucci, Rosanna RA Vila, Maya R. RA Adell, Teresa RA Diaz, Victor M. RA Tora, Montserrat RA Nakamura, Toshikazu RA Real, Francisco X. RT "Activation of the urokinase plasminogen activator/urokinase RT plasminogen activator receptor system and redistribution of E-cadherin RT are associated with hepatocyte growth factor-induced motility of RT pancreas tumor cells overexpressing Met."; RL Am. J. Pathol. 153:201-212(1998). // RX PubMed=9247707; DOI=10.1080/15216549700202901; RA Hatakeyama, Setsuko RA Gao, Yu-Hao RA Ohara-Nemoto, Yuko RA Kataoka, Hiroaki RA Satoh, Masanobu RT "Expression of bone morphogenetic proteins of human neoplastic RT epithelial cells."; RL Biochem. Mol. Biol. Int. 42:497-505(1997). // RX PubMed=18804159; DOI=10.1016/j.ygeno.2008.08.002; RA Jung, Jae-Joon RA Jeung, Hei-Cheul RA Chung, Hyun Cheol RA Lee, Jung Ok RA Kim, Tae Soo RA Kim, Yong Tai RA Noh, Sung Hoon RA Rha, Sun Young RT "In vitro pharmacogenomic database and chemosensitivity predictive RT genes in gastric cancer."; RL Genomics 93:52-61(2009). // RX PubMed=25343454; DOI=10.1371/journal.pone.0111146; PMCID=PMC4208810; RA Choong, Meng-Ling RA Tan, Shan-Ho RA Tan, Tuan-Zea RA Manesh, Sravanthy RA Ngo, Anna RA Yong, Jacklyn W.-Y. RA Yang, Henry He RA Lee, May Ann RT "Molecular integrative clustering of Asian gastric cell lines revealed RT two distinct chemosensitivity clusters."; RL PLoS ONE 9:e111146.1-e111146.9(2014). // RX CelloPub=CLPUB00581; RA Hojo, Haruto RT "Establishment of cultured cell lines of human stomach cancer origin RT and their morphological characteristics."; RL Niigata Igakkai Zasshi 91:737-763(1977). // RX PubMed=9023415; DOI=10.1006/cimm.1996.1062; RA Seki, Naoko RA Hoshino, Tomoaki RA Kikuchi, Megumi RA Hayashi, Akihiro RA Itoh, Kyogo RT "HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating RT lymphocytes of patients with non-small cell lung cancer."; RL Cell. Immunol. 175:101-110(1997). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981; RA Boegel, Sebastian RA Lower, Martin RA Bukur, Thomas RA Sahin, Ugur RA Castle, John C. RT "A catalog of HLA type, HLA expression, and neo-epitope candidates in RT human cancer cell lines."; RL OncoImmunology 3:e954893.1-e954893.12(2014). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=3986962; DOI=10.1093/carcin/6.4.549; RA Watatani, Masahiro RA Ikenaga, Mituo RA Hatanaka, Toshihiro RA Kinuta, Masakatsu RA Takai, Shin-ichiro RA Mori, Takesada RA Kondo, Sohei RT "Analysis of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced DNA RT damage in tumor cell strains from Japanese patients and demonstration RT of MNNG hypersensitivity of Mer xenografts in athymic nude mice."; RL Carcinogenesis 6:549-553(1985). // RX PubMed=1846553; DOI=10.1038/bjc.1991.14; PMCID=PMC1971664; RA Durrant, Lindy G. RA Watson, Susan A. RA Hall, A. RA Morris, David Lawson RT "Co-stimulation of gastrointestinal tumour cell growth by gastrin, RT transforming growth factor alpha and insulin like growth factor-I."; RL Br. J. Cancer 63:67-70(1991). // RX PubMed=2061947; DOI=10.1093/jnci/83.12.866; RA Watson, Susan A. RA Durrant, Lindy G. RA Wencyk, Pete M. RA Watson, A.L. RA Morris, David Lawson RT "Intracellular gastrin in human gastrointestinal tumor cells."; RL J. Natl. Cancer Inst. 83:866-871(1991). // RX PubMed=1933850; RA Yamada, Yukishige RA Yoshida, Teruhiko RA Hayashi, Kenshi RA Sekiya, Takao RA Yokota, Jun RA Hirohashi, Setsuo RA Nakatani, Katsunori RA Nakano, Hiroshige RA Sugimura, Takashi RA Terada, Masaaki RT "p53 gene mutations in gastric cancer metastases and in gastric cancer RT cell lines derived from metastases."; RL Cancer Res. 51:5800-5805(1991). // RX DOI=10.1016/j.procbio.2020.01.033; RA Pouremamali, Farhad RA Jeddi, Farhad RA Samadi, Nasser RT "Nrf2-ME-1 axis is associated with 5-FU resistance in gastric cancer RT cell line."; RL Process Biochem. 114:174-184(2022). //