ID   MDA-MB-468
AC   CVCL_0419
SY   MDA-MB 468; MDA-MB468; MDAMB468; MDA-468; MDA468; MB468; MD Anderson-Metastatic Breast-468
DR   BTO; BTO:0001570
DR   CLO; CLO_0007641
DR   EFO; EFO_0001216
DR   MCCL; MCC:0000316
DR   CLDB; cl4973
DR   AddexBio; C0006003/4673
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ArrayExpress; E-MTAB-6647
DR   ArrayExpress; E-TABM-157
DR   ArrayExpress; E-TABM-244
DR   ATCC; HTB-132
DR   BCRJ; 0166
DR   BioGRID_ORCS_Cell_line; 551
DR   BioSample; SAMN03473056
DR   BioSample; SAMN05292454
DR   BioSample; SAMN10988340
DR   cancercelllines; CVCL_0419
DR   CCRID; 1101HUM-PUMC000249
DR   CCRID; 3101HUMTCHu136
DR   Cell_Model_Passport; SIDM00628
DR   ChEMBL-Cells; CHEMBL3308424
DR   ChEMBL-Targets; CHEMBL614335
DR   CLS; 300279
DR   Cosmic; 809241
DR   Cosmic; 850823
DR   Cosmic; 871149
DR   Cosmic; 877448
DR   Cosmic; 897427
DR   Cosmic; 904384
DR   Cosmic; 908123
DR   Cosmic; 923061
DR   Cosmic; 934530
DR   Cosmic; 949192
DR   Cosmic; 991327
DR   Cosmic; 997921
DR   Cosmic; 1000125
DR   Cosmic; 1010920
DR   Cosmic; 1017167
DR   Cosmic; 1018467
DR   Cosmic; 1046929
DR   Cosmic; 1044224
DR   Cosmic; 1047691
DR   Cosmic; 1136363
DR   Cosmic; 1152526
DR   Cosmic; 1176635
DR   Cosmic; 1287918
DR   Cosmic; 1289402
DR   Cosmic; 1305384
DR   Cosmic; 1309004
DR   Cosmic; 1477427
DR   Cosmic; 1523775
DR   Cosmic; 1524344
DR   Cosmic; 1571795
DR   Cosmic; 1603223
DR   Cosmic; 1609465
DR   Cosmic; 1998490
DR   Cosmic; 2009514
DR   Cosmic; 2036673
DR   Cosmic; 2164999
DR   Cosmic; 2301533
DR   Cosmic; 2318380
DR   Cosmic; 2361357
DR   Cosmic; 2668276
DR   Cosmic-CLP; 908123
DR   DepMap; ACH-000849
DR   DSMZ; ACC-738
DR   DSMZCellDive; ACC-738
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 908123
DR   GEO; GSE184543
DR   GEO; GSM75169
DR   GEO; GSM185095
DR   GEO; GSM185096
DR   GEO; GSM217591
DR   GEO; GSM219929
DR   GEO; GSM344356
DR   GEO; GSM344406
DR   GEO; GSM350502
DR   GEO; GSM388214
DR   GEO; GSM421880
DR   GEO; GSM459714
DR   GEO; GSM459722
DR   GEO; GSM466357
DR   GEO; GSM783955
DR   GEO; GSM847418
DR   GEO; GSM847497
DR   GEO; GSM887301
DR   GEO; GSM888376
DR   GEO; GSM1008911
DR   GEO; GSM1053727
DR   GEO; GSM1172984
DR   GEO; GSM1214565
DR   GEO; GSM1238123
DR   GEO; GSM1374663
DR   GEO; GSM1374664
DR   GEO; GSM1374665
DR   GEO; GSM1401650
DR   GEO; GSM1556177
DR   GEO; GSM1556178
DR   GEO; GSM1556179
DR   GEO; GSM1556180
DR   GEO; GSM1556181
DR   GEO; GSM1661984
DR   GEO; GSM1670087
DR   GEO; GSM1833629
DR   GEO; GSM2124671
DR   GEO; GSM2258884
DR   GEO; GSM2258885
DR   GEO; GSM2258886
DR   GEO; GSM2258887
DR   GEO; GSM2258888
DR   GEO; GSM2258889
DR   GEO; GSM2258890
DR   GEO; GSM2258891
DR   GEO; GSM2258892
DR   GEO; GSM2258893
DR   GEO; GSM2258894
DR   GEO; GSM2258895
DR   GEO; GSM2258896
DR   GEO; GSM2258897
DR   GEO; GSM2258898
DR   GEO; GSM2258899
DR   GEO; GSM2258900
DR   GEO; GSM2258901
DR   GEO; GSM2258941
DR   GEO; GSM2258942
DR   GEO; GSM2258943
DR   IARC_TP53; 94
DR   IBRC; C10095
DR   ICLC; HTL99024
DR   KCB; KCB 2011114YJ
DR   LiGeA; CCLE_336
DR   LINCS_HMS; 50335
DR   LINCS_LDP; LCL-1471
DR   Lonza; 809
DR   NCBI_Iran; C208
DR   NCI-DTP; MDA-MB-468
DR   PharmacoDB; MDAMB468_907_2019
DR   PRIDE; PXD001680
DR   PRIDE; PXD005295
DR   PRIDE; PXD008222
DR   PRIDE; PXD022325
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0419
DR   PubChem_Cell_line; CVCL_0419
DR   SLKBase; 3578
DR   TOKU-E; 2401
DR   TOKU-E; 3604
DR   Ubigene; YC-D009
DR   Wikidata; Q16880225
RX   CelloPub=CLPUB00423;
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RX   PubMed=730202;
RX   PubMed=1961733;
RX   PubMed=3518877;
RX   PubMed=9671407;
RX   PubMed=10969801;
RX   PubMed=11414198;
RX   PubMed=12353263;
RX   PubMed=12800145;
RX   PubMed=15153330;
RX   PubMed=15677628;
RX   PubMed=16397213;
RX   PubMed=16541312;
RX   PubMed=17157791;
RX   PubMed=18262045;
RX   PubMed=18516279;
RX   PubMed=19582160;
RX   PubMed=19593635;
RX   PubMed=20070913;
RX   PubMed=20164919;
RX   PubMed=21778573;
RX   PubMed=22384151;
RX   PubMed=22460905;
RX   PubMed=22585861;
RX   PubMed=22628656;
RX   PubMed=23151021;
RX   PubMed=23601657;
RX   PubMed=23856246;
RX   PubMed=24094812;
RX   PubMed=24162158;
RX   PubMed=24176112;
RX   PubMed=24279929;
RX   PubMed=25485619;
RX   PubMed=25699542;
RX   PubMed=25877200;
RX   PubMed=25892236;
RX   PubMed=25960936;
RX   PubMed=26589293;
RX   PubMed=27377824;
RX   PubMed=27397505;
RX   PubMed=27807467;
RX   PubMed=28196595;
RX   PubMed=28287265;
RX   PubMed=28889351;
RX   PubMed=29273624;
RX   PubMed=30613774;
RX   PubMed=30787054;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=31978347;
RX   PubMed=32576280;
RX   PubMed=34703030;
RX   PubMed=35839778;
WW   https://en.wikipedia.org/wiki/MDA-MB-468
WW   https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm
WW   https://www.atcc.org/en/support/technical-support/faqs/htb-132-normal-growth-and-morphology
WW   https://www.synapse.org/#!Synapse:syn31544498
WW   https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/mda-mb-468.html
WW   http://dpsc.ccbr.utoronto.ca/cancer/get_cellline.pl?cellline=MDA-MB-468
WW   https://lincs.hms.harvard.edu/resources/reagents/icbp43/
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-53.html
WW   https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
WW   https://tcpaportal.org/mclp/
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: EGFR genetic alteration cell panel (ATCC TCP-1027).
CC   Part of: GrayJW breast cancer cell line panel.
CC   Part of: ICBP43 breast cancer cell line panel.
CC   Part of: KuDOS 95 cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: NCI-60 cancer cell line panel.
CC   Population: African American.
CC   Doubling time: 40.6 hours (PubMed=32576280); ~30-40 hours (DSMZ=ACC-738); 62 hours (NCI-DTP=MDA-MB-468); ~47 hours (PBCF); 79.76 hours (GrayJW panel).
CC   HLA typing: A*23:01,30:02; B*27:03,53:01; C*02:02,04:01 (PubMed=25960936).
CC   HLA typing: A*23:01,30:02; B*27:03,53:01; C*02:02,04:01; DQA1*02:01,05:02; DQB1*03:04,06:13; DRB1*04:03,13:100 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (PubMed=15677628; Sanger).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; c.253+1G>T; ClinVar=VCV000189475; Zygosity=Homozygous; Note=Splice donor mutation (PubMed=19593635).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; c.265_2787del2523; Zygosity=Homozygous (PubMed=19593635).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (PubMed=1961733; PubMed=16541312; PubMed=28889351; ATCC).
CC   Omics: Array-based CGH.
CC   Omics: CNV analysis.
CC   Omics: CRISPR phenotypic screen.
CC   Omics: Deep exome analysis.
CC   Omics: Deep proteome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: Fluorescence phenotype profiling.
CC   Omics: Genome sequenced.
CC   Omics: Glycoproteome analysis by proteomics.
CC   Omics: H2BK120ub ChIP-seq epigenome analysis.
CC   Omics: H3K23ac ChIP-seq epigenome analysis.
CC   Omics: H3K27ac ChIP-seq epigenome analysis.
CC   Omics: H3K27me3 ChIP-seq epigenome analysis.
CC   Omics: H3K36me3 ChIP-seq epigenome analysis.
CC   Omics: H3K4me1 ChIP-seq epigenome analysis.
CC   Omics: H3K4me3 ChIP-seq epigenome analysis.
CC   Omics: H3K79me2 ChIP-seq epigenome analysis.
CC   Omics: H3K9ac ChIP-seq epigenome analysis.
CC   Omics: H3K9me3 ChIP-seq epigenome analysis.
CC   Omics: H4K8ac ChIP-seq epigenome analysis.
CC   Omics: lncRNA expression profiling.
CC   Omics: Metabolome analysis.
CC   Omics: miRNA expression profiling.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=80.3%; Native American=0%; East Asian, North=6.19%; East Asian, South=0%; South Asian=0%; European, North=0%; European, South=13.51% (PubMed=30894373).
CC   Discontinued: CLS; 300279; true.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): AddexBio; ATCC; CCRID; Cosmic-CLP; DSMZ; Genomics_Center_BCF_Technion; PubMed=25877200; PubMed=28889351
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 13
ST   D12S391: 18
ST   D13S317: 12
ST   D16S539: 9
ST   D18S51: 17
ST   D19S433: 12,13
ST   D1S1656: 11,14
ST   D21S11: 27 (CCRID)
ST   D21S11: 27,28 (DSMZ; Genomics_Center_BCF_Technion; PubMed=25877200; PubMed=28889351)
ST   D22S1045: 10
ST   D2S1338: 17,25
ST   D2S441: 12,14
ST   D3S1358: 15
ST   D5S818: 12
ST   D7S820: 8
ST   D8S1179: 13
ST   FGA: 23
ST   Penta D: 8,10
ST   Penta E: 5
ST   TH01: 7
ST   TPOX: 8,9
ST   vWA: 18
DI   NCIt; C5214; Breast adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   51Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 47
//
RX   CelloPub=CLPUB00423;
RA   Morrison B.J.;
RT   "Breast cancer stem cells: tumourspheres and implications for therapy.";
RL   Thesis PhD (2010), Griffith University, Australia.
//
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RA   Leibovitz A.;
RT   "Cell lines from human breast.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York (1994).
//
RX   PubMed=730202; DOI=10.1007/BF02616120;
RA   Cailleau R.M., Olive M., Cruciger Q.V.J.;
RT   "Long-term human breast carcinoma cell lines of metastatic origin:
RT   preliminary characterization.";
RL   In Vitro 14:911-915(1978).
//
RX   PubMed=1961733; DOI=10.1073/pnas.88.23.10657;
RA   Runnebaum I.B., Nagarajan M., Bowman M., Soto D., Sukumar S.;
RT   "Mutations in p53 as potential molecular markers for human breast
RT   cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:10657-10661(1991).
//
RX   PubMed=3518877; DOI=10.3109/07357908609038260;
RA   Fogh J.;
RT   "Human tumor lines for cancer research.";
RL   Cancer Invest. 4:157-184(1986).
//
RX   PubMed=9671407; DOI=10.1038/sj.onc.1201814;
RA   Sweeney K.J., Swarbrick A., Sutherland R.L., Musgrove E.A.;
RT   "Lack of relationship between CDK activity and G1 cyclin expression in
RT   breast cancer cells.";
RL   Oncogene 16:2865-2878(1998).
//
RX   PubMed=10969801;
RA   Forozan F., Mahlamaki E.H., Monni O., Chen Y.-D., Veldman R., Jiang Y.,
RA   Gooden G.C., Ethier S.P., Kallioniemi A., Kallioniemi O.-P.;
RT   "Comparative genomic hybridization analysis of 38 breast cancer cell
RT   lines: a basis for interpreting complementary DNA microarray data.";
RL   Cancer Res. 60:4519-4525(2000).
//
RX   PubMed=11414198; DOI=10.1007/s004320000207;
RA   Lahm H., Andre S., Hoeflich A., Fischer J.R., Sordat B., Kaltner H.,
RA   Wolf E., Gabius H.-J.;
RT   "Comprehensive galectin fingerprinting in a panel of 61 human tumor
RT   cell lines by RT-PCR and its implications for diagnostic and
RT   therapeutic procedures.";
RL   J. Cancer Res. Clin. Oncol. 127:375-386(2001).
//
RX   PubMed=12353263; DOI=10.1002/gcc.10107;
RA   Popovici C., Basset C., Bertucci F., Orsetti B., Adelaide J.,
RA   Mozziconacci M.-J., Conte N., Murati A., Ginestier C.,
RA   Charafe-Jauffret E., Ethier S.P., Lafage-Pochitaloff M., Theillet C.,
RA   Birnbaum D., Chaffanet M.;
RT   "Reciprocal translocations in breast tumor cell lines: cloning of a
RT   t(3;20) that targets the FHIT gene.";
RL   Genes Chromosomes Cancer 35:204-218(2002).
//
RX   PubMed=12800145; DOI=10.1002/gcc.10218;
RA   Adelaide J., Huang H.-E., Murati A., Alsop A.E., Orsetti B.,
RA   Mozziconacci M.-J., Popovici C., Ginestier C., Letessier A.,
RA   Basset C., Courtay-Cahen C., Jacquemier J., Theillet C., Birnbaum D.,
RA   Edwards P.A.W., Chaffanet M.;
RT   "A recurrent chromosome translocation breakpoint in breast and
RT   pancreatic cancer cell lines targets the neuregulin/NRG1 gene.";
RL   Genes Chromosomes Cancer 37:333-345(2003).
//
RX   PubMed=15153330; DOI=10.1593/neo.3292;
RA   Watts G.S., Oshiro M.M., Junk D.J., Wozniak R.J., Watterson S.J.,
RA   Domann F.E., Futscher B.W.;
RT   "The acetyltransferase p300/CBP-associated factor is a p53 target gene
RT   in breast tumor cells.";
RL   Neoplasia 6:187-194(2004).
//
RX   PubMed=15677628; DOI=10.1093/carcin/bgi032;
RA   Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C.,
RA   Edwards P.A.W., Caldas C.;
RT   "Evidence that both genetic instability and selection contribute to
RT   the accumulation of chromosome alterations in cancer.";
RL   Carcinogenesis 26:923-930(2005).
//
RX   PubMed=16397213; DOI=10.1158/0008-5472.CAN-05-2853;
RA   Elstrodt F., Hollestelle A., Nagel J.H.A., Gorin M., Wasielewski M.,
RA   van den Ouweland A., Merajver S.D., Ethier S.P., Schutte M.;
RT   "BRCA1 mutation analysis of 41 human breast cancer cell lines reveals
RT   three new deleterious mutants.";
RL   Cancer Res. 66:41-45(2006).
//
RX   PubMed=16541312; DOI=10.1007/s10549-006-9186-z;
RA   Wasielewski M., Elstrodt F., Klijn J.G.M., Berns E.M.J.J., Schutte M.;
RT   "Thirteen new p53 gene mutants identified among 41 human breast cancer
RT   cell lines.";
RL   Breast Cancer Res. Treat. 99:97-101(2006).
//
RX   PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008;
RA   Neve R.M., Chin K., Fridlyand J., Yeh J., Baehner F.L., Fevr T.,
RA   Clark L., Bayani N., Coppe J.-P., Tong F., Speed T., Spellman P.T.,
RA   DeVries S., Lapuk A., Wang N.J., Kuo W.-L., Stilwell J.L., Pinkel D.,
RA   Albertson D.G., Waldman F.M., McCormick F., Dickson R.B.,
RA   Johnson M.D., Lippman M.E., Ethier S.P., Gazdar A.F., Gray J.W.;
RT   "A collection of breast cancer cell lines for the study of
RT   functionally distinct cancer subtypes.";
RL   Cancer Cell 10:515-527(2006).
//
RX   PubMed=18262045; DOI=10.1016/j.cancergencyto.2007.05.030;
RA   Xu J., Chambers A.F., Tuck A.B., Rodenhiser D.I.;
RT   "Molecular cytogenetic characterization of human breast cancer cell
RT   line MDA-MB-468 and its variant 468LN, which displays aggressive
RT   lymphatic metastasis.";
RL   Cancer Genet. Cytogenet. 181:1-7(2008).
//
RX   PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004;
RA   Kenny P.A., Lee G.Y., Myers C.A., Neve R.M., Semeiks J.R.,
RA   Spellman P.T., Lorenz K., Lee E.H., Barcellos-Hoff M.H.,
RA   Petersen O.W., Gray J.W., Bissell M.J.;
RT   "The morphologies of breast cancer cell lines in three-dimensional
RT   assays correlate with their profiles of gene expression.";
RL   Mol. Oncol. 1:84-96(2007).
//
RX   PubMed=19582160; DOI=10.1371/journal.pone.0006146;
RA   Kao J., Salari K., Bocanegra M., Choi Y.-L., Girard L., Gandhi J.,
RA   Kwei K.A., Hernandez-Boussard T., Wang P., Gazdar A.F., Minna J.D.,
RA   Pollack J.R.;
RT   "Molecular profiling of breast cancer cell lines defines relevant
RT   tumor models and provides a resource for cancer gene discovery.";
RL   PLoS ONE 4:E6146-E6146(2009).
//
RX   PubMed=19593635; DOI=10.1007/s10549-009-0460-8;
RA   Hollestelle A., Nagel J.H.A., Smid M., Lam S., Elstrodt F.,
RA   Wasielewski M., Ng S.S., French P.J., Peeters J.K., Rozendaal M.J.,
RA   Riaz M., Koopman D.G., ten Hagen T.L.M., de Leeuw B.H.C.G.M.,
RA   Zwarthoff E.C., Teunisse A., van der Spek P.J., Klijn J.G.M.,
RA   Dinjens W.N.M., Ethier S.P., Clevers H.C., Jochemsen A.G.,
RA   den Bakker M.A., Foekens J.A., Martens J.W.M., Schutte M.;
RT   "Distinct gene mutation profiles among luminal-type and basal-type
RT   breast cancer cell lines.";
RL   Breast Cancer Res. Treat. 121:53-64(2010).
//
RX   PubMed=20070913; DOI=10.1186/1471-2407-10-15;
RA   Tsuji K., Kawauchi S., Saito S., Furuya T., Ikemoto K., Nakao M.,
RA   Yamamoto S., Oka M., Hirano T., Sasaki K.;
RT   "Breast cancer cell lines carry cell line-specific genomic alterations
RT   that are distinct from aberrations in breast cancer tissues:
RT   comparison of the CGH profiles between cancer cell lines and primary
RT   cancer tissues.";
RL   BMC Cancer 10:15.1-15.10(2010).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=21778573; DOI=10.3233/BD-2010-0307;
RA   Chavez K.J., Garimella S.V., Lipkowitz S.;
RT   "Triple negative breast cancer cell lines: one tool in the search for
RT   better treatment of triple negative breast cancer.";
RL   Breast Dis. 32:35-48(2010).
//
RX   PubMed=22384151; DOI=10.1371/journal.pone.0032096;
RA   Lee J.-S., Kim Y.K., Kim H.J., Hajar S., Tan Y.L., Kang N.-Y., Ng S.H.,
RA   Yoon C.N., Chang Y.-T.;
RT   "Identification of cancer cell-line origins using fluorescence
RT   image-based phenomic screening.";
RL   PLoS ONE 7:E32096-E32096(2012).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224;
RA   Marcotte R., Brown K.R., Suarez Saiz F.J., Sayad A., Karamboulas K.,
RA   Krzyzanowski P.M., Sircoulomb F., Medrano M., Fedyshyn Y., Koh J.L.Y.,
RA   van Dyk D., Fedyshyn B., Luhova M., Brito G.C., Vizeacoumar F.J.,
RA   Vizeacoumar F.S., Datti A., Kasimer D., Buzina A., Mero P.,
RA   Misquitta C., Normand J., Haider M., Ketela T., Wrana J.L.,
RA   Rottapel R., Neel B.G., Moffat J.;
RT   "Essential gene profiles in breast, pancreatic, and ovarian cancer
RT   cells.";
RL   Cancer Discov. 2:172-189(2012).
//
RX   PubMed=22628656; DOI=10.1126/science.1218595;
RA   Jain M., Nilsson R., Sharma S., Madhusudhan N., Kitami T., Souza A.L.,
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