ID   LN-229
AC   CVCL_0393
SY   LN 229; LN229; LNT-229
DR   BTO; BTO_0002004
DR   CLO; CLO_0007363
DR   EFO; EFO_0006637
DR   MCCL; MCC:0000288
DR   AddexBio; C0005017/4993
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-2611
DR   BioGRID_ORCS_Cell_line; 929
DR   BioSample; SAMN03471191
DR   BioSample; SAMN03471692
DR   BioSample; SAMN10987619
DR   cancercelllines; CVCL_0393
DR   Cell_Model_Passport; SIDM00684
DR   ChEMBL-Cells; CHEMBL4295402
DR   ChEMBL-Targets; CHEMBL4296459
DR   CLS; 305043
DR   Cosmic; 849861
DR   Cosmic; 1746958
DR   Cosmic; 1995485
DR   Cosmic; 2302323
DR   Cosmic; 2367492
DR   Cosmic; 2491102
DR   Cosmic; 2516025
DR   Cosmic; 2580915
DR   Cosmic-CLP; 1240169
DR   DepMap; ACH-000595
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 1240169
DR   GEO; GSM101615
DR   GEO; GSM101616
DR   GEO; GSM326200
DR   GEO; GSM397665
DR   GEO; GSM397666
DR   GEO; GSM481416
DR   GEO; GSM887270
DR   GEO; GSM888345
DR   GEO; GSM1374621
DR   GEO; GSM1670049
DR   GEO; GSM2113428
DR   GEO; GSM2113429
DR   GEO; GSM2113430
DR   GEO; GSM2113431
DR   IARC_TP53; 30212
DR   LiGeA; CCLE_871
DR   LINCS_LDP; LCL-1354
DR   Lonza; 1322
DR   PharmacoDB; LN229_841_2019
DR   PRIDE; PXD000589
DR   PRIDE; PXD003790
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0393
DR   PubChem_Cell_line; CVCL_0393
DR   Ubigene; YC-A021
DR   Wikidata; Q54902771
RX   DOI=10.1007/0-306-46861-1_11;
RX   PubMed=7693337;
RX   PubMed=8509230;
RX   PubMed=9842975;
RX   PubMed=10416987;
RX   PubMed=14614447;
RX   PubMed=14655754;
RX   PubMed=16697959;
RX   PubMed=17595512;
RX   PubMed=19365568;
RX   PubMed=20504876;
RX   PubMed=21406405;
RX   PubMed=22460905;
RX   PubMed=22570425;
RX   PubMed=25485619;
RX   PubMed=25772239;
RX   PubMed=25877200;
RX   PubMed=25894527;
RX   PubMed=25984343;
RX   PubMed=26496030;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=27412690;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=31978347;
RX   PubMed=35839778;
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/brain-cancer-xenograft/ln-229-xenograft-model/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Population: Caucasian.
CC   Doubling time: 24 hours (PubMed=9842975); 31 hours (PubMed=25984343).
CC   HLA typing: A*03:01:01; B*35:01; C*04:01:01 (PubMed=27412690).
CC   HLA typing: A*03:01,03:01; B*35:01,35:01; C*04:01,04:01; DQA1*01:01,01:01; DQB1*05:01,05:01; DRB1*01:01,11:19 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=9842975).
CC   Sequence variation: Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (Cosmic-CLP=1240169).
CC   Sequence variation: Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (Cosmic-CLP=1240169).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (PubMed=10416987; Cosmic-CLP=1240169).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Phenotyping; shRNA library screening.
CC   Omics: Proteomics.
CC   Omics: Proteomics; HLA class I peptidome.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Proteomics; Subcellular; Cell surface.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=2.23%; East Asian, South=0%; South Asian=0.02%; European, North=59.47%; European, South=38.27% (PubMed=30894373).
CC   Misspelling: LN22; Cosmic=2580915.
CC   Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
ST   Source(s): AddexBio=C0005017/4993; ATCC=CRL-2611; Cosmic-CLP=1240169; PubMed=22570425; PubMed=25877200; Technion Genomics Center
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 16
ST   D12S391: 20,22
ST   D13S317: 10,11
ST   D16S539: 12
ST   D18S51: 13,15
ST   D19S433: 12,17.2
ST   D1S1656: 14,17
ST   D21S11: 29,30
ST   D22S1045: 15,16
ST   D2S1338: 19,20
ST   D2S441: 10,11
ST   D3S1358: 16,17
ST   D5S818: 11 (PubMed=25877200)
ST   D5S818: 11,12 (AddexBio=C0005017/4993; ATCC=CRL-2611; Cosmic-CLP=1240169; PubMed=22570425; Technion Genomics Center)
ST   D7S820: 8,11 (AddexBio=C0005017/4993; ATCC=CRL-2611; Cosmic-CLP=1240169; PubMed=22570425; Technion Genomics Center)
ST   D7S820: 11 (PubMed=25877200)
ST   D8S1179: 13,14
ST   FGA: 23
ST   Penta D: 10,11
ST   Penta E: 7,16
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 16,19
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 43
CH   CVCL_F1RD ! HyCyte LN-229 KO-hAP1S1
CH   CVCL_F1RE ! HyCyte LN-229 KO-hSMARCAL1
CH   CVCL_D7FE ! LN-229-EGFP
CH   CVCL_D7FD ! LN-229-Luc
CH   CVCL_WS33 ! LN-229_indWIF1
CH   CVCL_E8NR ! LN229-CHID1
CH   CVCL_D2RW ! LN229/CD133
CH   CVCL_D2TH ! LN229/CD19
CH   CVCL_D2TI ! LN229/CD19ec
CH   CVCL_A8V5 ! LN229/CD20
CH   CVCL_D2TV ! LN229/ectodomain-PODXL
CH   CVCL_D2SN ! LN229/EGFR
CH   CVCL_D2T3 ! LN229/HER2
CH   CVCL_D2S5 ! LN229/hPD-L1
CH   CVCL_D2U6 ! LN229/hPDPN
CH   CVCL_D2R8 ! LN229/mCCR3
CH   CVCL_D2RM ! LN229/mCD39
CH   CVCL_D2SJ ! LN229/mEGFR
CH   CVCL_D2SR ! LN229/mHER2
CH   CVCL_D2TU ! LN229/PODXL
CH   CVCL_D2TP ! PDIS-13
CH   CVCL_E0XD ! Ubigene LN-229 PICALM KO
CH   CVCL_E0XE ! Ubigene LN-229 RSRP1 KO
//
RX   PubMed=20504876; DOI=10.1093/neuonc/noq051; PMCID=PMC2940700;
RA   Berger, Benjamin
RA   Capper, David
RA   Lemke, Dieter
RA   Pfenning, Philipp-Niclas
RA   Platten, Michael
RA   Weller, Michael
RA   von Deimling, Andreas
RA   Wick, Wolfgang
RA   Weiler, Markus
RT   "Defective p53 antiangiogenic signaling in glioblastoma.";
RL   Neuro-oncol. 12:894-907(2010).
//
RX   PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x; PMCID=PMC8098486;
RA   Ishii, Nobuaki
RA   Maier, Daniel
RA   Merlo, Adrian
RA   Tada, Mitsuhiro
RA   Sawamura, Yutaka
RA   Diserens, Annie-Claire
RA   Van Meir, Erwin G.
RT   "Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor
RT   suppressor genes in human glioma cell lines.";
RL   Brain Pathol. 9:469-479(1999).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347;
RA   Bausch-Fluck, Damaris
RA   Hofmann, Andreas
RA   Bock, Thomas
RA   Frei, Andreas P.
RA   Cerciello, Ferdinando
RA   Jacobs, Andrea
RA   Moest, Hansjoerg
RA   Omasits, Ulrich
RA   Gundry, Rebekah L.
RA   Yoon, Charles
RA   Schiess, Ralph
RA   Schmidt, Alexander
RA   Mirkowska, Paulina
RA   Hartlova, Anetta Svitorka
RA   Van Eyk, Jennifer Eileen
RA   Bourquin, Jean-Pierre
RA   Aebersold, Ruedi
RA   Boheler, Kenneth R.
RA   Zandstra, Peter W.
RA   Wollscheid, Bernd
RT   "A mass spectrometric-derived cell surface protein atlas.";
RL   PLoS ONE 10:e0121314.1-e0121314.22(2015).
//
RX   PubMed=14614447; DOI=10.1038/sj.onc.1207198;
RA   Wischhusen, Jorg
RA   Naumann, Ulrike
RA   Ohgaki, Hiroko
RA   Rastinejad, Farzan
RA   Weller, Michael
RT   "CP-31398, a novel p53-stabilizing agent, induces p53-dependent and
RT   p53-independent glioma cell death.";
RL   Oncogene 22:8233-8245(2003).
//
RX   PubMed=30971826; DOI=10.1038/s41586-019-1103-9;
RA   Behan, Fiona M.
RA   Iorio, Francesco
RA   Picco, Gabriele
RA   Goncalves, Emanuel
RA   Beaver, Charlotte M.
RA   Migliardi, Giorgia
RA   Santos, Rita
RA   Rao, Yanhua
RA   Sassi, Francesco
RA   Pinnelli, Marika
RA   Ansari, Rizwan
RA   Harper, Sarah
RA   Jackson, David Adam
RA   McRae, Rebecca
RA   Pooley, Rachel
RA   Wilkinson, Piers
RA   van der Meer, Dieudonne J.
RA   Dow, David
RA   Buser-Doepner, Carolyn A.
RA   Bertotti, Andrea
RA   Trusolino, Livio
RA   Stronach, Euan Alexander
RA   Saez-Rodriguez, Julio
RA   Yusa, Kosuke
RA   Garnett, Mathew J.
RT   "Prioritization of cancer therapeutic targets using CRISPR-Cas9
RT   screens.";
RL   Nature 568:511-516(2019).
//
RX   PubMed=21406405; DOI=10.1158/0008-5472.CAN-10-3112;
RA   Grzmil, Michal
RA   Morin, Pier Jr.
RA   Lino, Maria Maddalena
RA   Merlo, Adrian
RA   Frank, Stephan
RA   Wang, Yu-Hua
RA   Moncayo, Gerald
RA   Hemmings, Brian Arthur
RT   "MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-beta
RT   signaling pathway in human glioblastoma.";
RL   Cancer Res. 71:2392-2402(2011).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   DOI=10.1007/0-306-46861-1_11;
RA   Ali-Osman, Francis
RT   "Brain tumors.";
RL   (In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999).
//
RX   PubMed=26496030; DOI=10.18632/oncotarget.6171; PMCID=PMC4791243;
RA   Patil, Vikas
RA   Pal, Jagriti
RA   Somasundaram, Kumaravel
RT   "Elucidating the cancer-specific genetic alteration spectrum of
RT   glioblastoma derived cell lines from whole exome and RNA sequencing.";
RL   Oncotarget 6:43452-43471(2015).
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254;
RA   Nusinow, David Paul
RA   Szpyt, John
RA   Ghandi, Mahmoud
RA   Rose, Christopher M.
RA   McDonald, E. Robert 3rd
RA   Kalocsay, Marian
RA   Jane-Valbuena, Judit
RA   Gelfand, Ellen T.
RA   Schweppe, Devin Karl
RA   Jedrychowski, Mark P.
RA   Golji, Javad
RA   Porter, Dale A.
RA   Rejtar, Tomas
RA   Wang, Y. Karen
RA   Kryukov, Gregory V.
RA   Stegmeier, Frank
RA   Erickson, Brian K.
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RA   Gygi, Steven P.
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
//
RX   PubMed=9842975; DOI=10.1002/(SICI)1097-0215(19981218)79:6<640::AID-IJC15>3.0.CO;2-Z;
RA   Weller, Michael
RA   Rieger, Johannes
RA   Grimmel, Cornelia
RA   Van Meir, Erwin G.
RA   De Tribolet, Nicolas
RA   Krajewski, Stanislaw
RA   Reed, John C.
RA   von Deimling, Andreas
RA   Dichgans, Johannes
RT   "Predicting chemoresistance in human malignant glioma cells: the role
RT   of molecular genetic analyses.";
RL   Int. J. Cancer 79:640-644(1998).
//
RX   PubMed=7693337;
RA   Li, Hong
RA   Hamou, Marie-France
RA   de Tribolet, Nicolas
RA   Jaufeerally, Rebana
RA   Hofmann, Martin
RA   Diserens, Annie-Claire
RA   Van Meir, Erwin G.
RT   "Variant CD44 adhesion molecules are expressed in human brain
RT   metastases but not in glioblastomas.";
RL   Cancer Res. 53:5345-5349(1993).
//
RX   PubMed=25772239; DOI=10.1038/onc.2015.61;
RA   Vassallo, Irene
RA   Zinn, Pascal O.
RA   Lai, Marta
RA   Rajakannu, Premnath
RA   Hamou, Marie-France
RA   Hegi, Monika E.
RT   "WIF1 re-expression in glioblastoma inhibits migration through
RT   attenuation of non-canonical WNT signaling by downregulating the
RT   lncRNA MALAT1.";
RL   Oncogene 35:12-21(2016).
//
RX   PubMed=16697959; DOI=10.1016/j.ccr.2006.03.030;
RA   Lee, Jeongwu
RA   Kotliarova, Svetlana
RA   Kotliarov, Yuri
RA   Li, Ai-Guo
RA   Su, Qin
RA   Donin, Nicholas Murray
RA   Pastorino, Sandra
RA   Purow, Benjamin W.
RA   Christopher, Neil
RA   Zhang, Wei
RA   Park, John K.
RA   Fine, Howard Alan
RT   "Tumor stem cells derived from glioblastomas cultured in bFGF and EGF
RT   more closely mirror the phenotype and genotype of primary tumors than
RT   do serum-cultured cell lines.";
RL   Cancer Cell 9:391-403(2006).
//
RX   PubMed=19365568; DOI=10.1371/journal.pone.0005209; PMCID=PMC2666263;
RA   Bax, Dorine Arjanne
RA   Little, Suzanne E.
RA   Gaspar, Nathalie
RA   Perryman, Lara
RA   Marshall, Lynley
RA   Viana-Pereira, Marta
RA   Jones, Tania A.
RA   Williams, Richard D.
RA   Grigoriadis, Anita
RA   Vassal, Gilles
RA   Workman, Paul
RA   Sheer, Denise
RA   Reis, Rui Manuel
RA   Pearson, Andrew D.J.
RA   Hargrave, Darren
RA   Jones, Chris
RT   "Molecular and phenotypic characterisation of paediatric glioma cell
RT   lines as models for preclinical drug development.";
RL   PLoS ONE 4:e5209.1-e5209.9(2009).
//
RX   PubMed=27412690; DOI=10.1074/mcp.M116.060350; PMCID=PMC5013317;
RA   Shraibman, Bracha
RA   Kadosh, Dganit Melamed
RA   Barnea, Eilon
RA   Admon, Arie
RT   "Human leukocyte antigen (HLA) peptides derived from tumor antigens
RT   induced by inhibition of DNA methylation for development of
RT   drug-facilitated immunotherapy.";
RL   Mol. Cell. Proteomics 15:3058-3070(2016).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=14655754; DOI=10.1111/j.1750-3639.2003.tb00479.x; PMCID=PMC8095903;
RA   Bahr, Oliver
RA   Rieger, Johannes
RA   Duffner, Frank
RA   Meyermann, Richard
RA   Weller, Michael
RA   Wick, Wolfgang
RT   "P-glycoprotein and multidrug resistance-associated protein mediate
RT   specific patterns of multidrug resistance in malignant glioma cell
RT   lines, but not in primary glioma cells.";
RL   Brain Pathol. 13:482-494(2003).
//
RX   PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652;
RA   Cowley, Glenn S.
RA   Weir, Barbara A.
RA   Vazquez, Francisca
RA   Tamayo, Pablo
RA   Scott, Justine A.
RA   Rusin, Scott
RA   East-Seletsky, Alexandra
RA   Ali, Levi D.
RA   Gerath, William F.J.
RA   Pantel, Sarah E.
RA   Lizotte, Patrick Hall
RA   Jiang, Guo-Zhi
RA   Hsiao, Jessica
RA   Tsherniak, Aviad
RA   Dwinell, Elizabeth
RA   Aoyama, Simon
RA   Okamoto, Michael
RA   Harrington, William
RA   Gelfand, Ellen T.
RA   Green, Thomas M.
RA   Tomko, Mark J.
RA   Gopal, Shuba
RA   Wong, Terence C.
RA   Li, Hu-Bo
RA   Howell, Sara
RA   Stransky, Nicolas
RA   Liefeld, Ted
RA   Jang, Dongkeun
RA   Bistline, Jonathan
RA   Meyers, Barbara Hill
RA   Armstrong, Scott Allen
RA   Anderson, Kenneth Carl
RA   Stegmaier, Kimberly
RA   Reich, Michael
RA   Pellman, David
RA   Boehm, Jesse S.
RA   Mesirov, Jill P.
RA   Golub, Todd Robert
RA   Root, David E.
RA   Hahn, William Chun
RT   "Parallel genome-scale loss of function screens in 216 cancer cell
RT   lines for the identification of context-specific genetic
RT   dependencies.";
RL   Sci. Data 1:140035.1-140035.12(2014).
//
RX   PubMed=17595512; DOI=10.1159/000104150;
RA   Rieger, Johannes
RA   Frank, Brigitte
RA   Weller, Michael
RA   Wick, Wolfgang
RT   "Mechanisms of resistance of human glioma cells to Apo2
RT   ligand/TNF-related apoptosis-inducing ligand.";
RL   Cell. Physiol. Biochem. 20:23-34(2007).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura Eleanor
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844;
RA   Bady, Pierre
RA   Diserens, Annie-Claire
RA   Castella, Vincent
RA   Kalt, Stefanie
RA   Heinimann, Karl
RA   Hamou, Marie-France
RA   Delorenzi, Mauro
RA   Hegi, Monika E.
RT   "DNA fingerprinting of glioma cell lines and considerations on
RT   similarity measurements.";
RL   Neuro-oncol. 14:701-711(2012).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=8509230; DOI=10.1002/ijc.2910540329;
RA   Rimoldi, Donata
RA   Romero, Pedro
RA   Carrel, Stefan
RT   "The human melanoma antigen-encoding gene, MAGE-1, is expressed by
RT   other tumour cells of neuroectodermal origin such as glioblastomas and
RT   neuroblastomas.";
RL   Int. J. Cancer 54:527-528(1993).
//