ID   L6
AC   CVCL_0385
SY   L-6; L-6 myoblast
DR   BTO; BTO_0002809
DR   CLO; CLO_0007203
DR   EFO; EFO_0022767
DR   MCCL; MCC:0000280
DR   CLDB; cl3142
DR   CLDB; cl5220
DR   ABM; T0771
DR   ATCC; CRL-1458
DR   BCRJ; 0141
DR   CCRID; 1101RAT-PUMC000192
DR   CCRID; 3101RATGNR4
DR   ChEMBL-Cells; CHEMBL3308469
DR   ChEMBL-Targets; CHEMBL614793
DR   CLS; 305231
DR   IZSLER; BS CL 134
DR   JCRB; IFO50364
DR   JCRB; JCRB9081
DR   KCLB; 21458
DR   Kerafast; ESK201-FP
DR   Lonza; 927
DR   PRIDE; PXD002557
DR   PubChem_Cell_line; CVCL_0385
DR   Wikidata; Q54901051
RX   PubMed=1311324;
RX   PubMed=5245982;
RX   PubMed=5481965;
RX   PubMed=7297605;
RX   PubMed=10484371;
RX   PubMed=33117511;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-130.html
CC   Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
CC   Anecdotal: Called L6 by David Yaffe because he and Sara Neuman established the cell line during the Six-Day war in 1967 (PubMed=33117511).
CC   Derived from site: In situ; Thigh, skeletal muscle; UBERON=UBERON_0004252.
CC   Cell type: Myoblast; CL=CL_0000056.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
AG   1D
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 30
CH   CVCL_0P25 ! L6-GLUT4myc
CH   CVCL_3834 ! L6.C10
CH   CVCL_3835 ! L6.C11
CH   CVCL_3836 ! L6.G8
CH   CVCL_3837 ! L6.G8.C5
CH   CVCL_C569 ! L6A4
CH   CVCL_3387 ! L6C5
CH   CVCL_C570 ! L6C9
CH   CVCL_UI07 ! L6Cl1
CH   CVCL_UI08 ! L6Cl2
CH   CVCL_UI09 ! L6Cl5
CH   CVCL_UI10 ! L6Cl6
CH   CVCL_C8RC ! L6E
CH   CVCL_0386 ! L6E9
CH   CVCL_3388 ! L6H2
CH   CVCL_6F18 ! L6J1
CH   CVCL_C565 ! L6TG
//
RX   PubMed=7297605; DOI=10.1016/0014-4827(81)90032-X;
RA   Parfett, Craig Leroy John
RA   Jamieson, James Chilles
RA   Wright, Jim A.
RT   "A correlation between loss of fusion potential and defective
RT   formation of mannose-linked lipid intermediates in independent
RT   concanavalin A-resistant myoblast cell lines.";
RL   Exp. Cell Res. 136:1-14(1981).
//
RX   PubMed=5481965; DOI=10.1016/S0012-1606(70)80004-5;
RA   Richler, Carmelit
RA   Yaffe, David
RT   "The in vitro cultivation and differentiation capacities of myogenic
RT   cell lines.";
RL   Dev. Biol. 23:1-22(1970).
//
RX   PubMed=5245982; DOI=10.1073/pnas.61.2.477; PMCID=PMC225183;
RA   Yaffe, David
RT   "Retention of differentiation potentialities during prolonged
RT   cultivation of myogenic cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 61:477-483(1968).
//
RX   PubMed=10484371; DOI=10.1152/ajpendo.1999.277.3.E572;
RA   Ueyama, Atsunori
RA   Yaworsky, Karen L.
RA   Wang, Qing-Hua
RA   Ebina, Yousuke
RA   Klip, Amira
RT   "GLUT-4myc ectopic expression in L6 myoblasts generates a
RT   GLUT-4-specific pool conferring insulin sensitivity.";
RL   Am. J. Physiol. 277:E572-E578(1999).
//
RX   PubMed=33117511; DOI=10.4081/ejtm.2020.9306; PMCID=PMC7582454;
RA   Yablonka-Reuveni, Zipora
RA   Stockdale, Frank E.
RA   Nudel, Uri
RA   Israeli, David
RA   Blau, Helen Margaret
RA   Shainberg, Asher
RA   Neuman, Sara
RA   Kessler-Icekson, Gania
RA   Krull, Erica Meghid
RA   Paterson, Bruce
RA   Saxel Fuchs, Ora
RA   Greenberg, David
RA   Sarig, Rachel
RA   Halevy, Orna
RA   Ozawa, Eijiro
RA   Katcoff, Don J.
RT   "Farewell to professor David Yaffe -- a pillar of the myogenesis
RT   field.";
RL   Eur. J. Transl. Myol. 30:9306.1-9306.16(2020).
//
RX   PubMed=1311324; DOI=10.1016/S0021-9258(18)42923-7;
RA   Mitsumoto, Yasuhide
RA   Klip, Amira
RT   "Development regulation of the subcellular distribution and
RT   glycosylation of GLUT1 and GLUT4 glucose transporters during
RT   myogenesis of L6 muscle cells.";
RL   J. Biol. Chem. 267:4957-4962(1992).
//