ID Hs 578T AC CVCL_0332 SY HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells DR BTO; BTO_0003885 DR CLO; CLO_0004009 DR EFO; EFO_0001192 DR MCCL; MCC:0000228 DR CLDB; cl1716 DR CLDB; cl1717 DR CLDB; cl5023 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ArrayExpress; E-TABM-157 DR ArrayExpress; E-TABM-244 DR ATCC; CRL-7849 DR ATCC; HTB-126 DR BCRC; 60120 DR BioGRID_ORCS_Cell_line; 654 DR BioSample; SAMN03473213 DR BioSample; SAMN10987893 DR cancercelllines; CVCL_0332 DR CCRID; 1101HUM-PUMC000670 DR CCRID; 3101HUMTCHu127 DR CCRID; 4201HUM-CCTCC00252 DR CCTCC; GDC0252 DR Cell_Model_Passport; SIDM00135 DR ChEMBL-Cells; CHEMBL3307672 DR ChEMBL-Targets; CHEMBL614645 DR CLS; 305089 DR Cosmic; 871142 DR Cosmic; 875877 DR Cosmic; 897418 DR Cosmic; 904372 DR Cosmic; 905957 DR Cosmic; 921973 DR Cosmic; 934524 DR Cosmic; 974234 DR Cosmic; 979715 DR Cosmic; 997928 DR Cosmic; 1010929 DR Cosmic; 1017164 DR Cosmic; 1018473 DR Cosmic; 1027051 DR Cosmic; 1044232 DR Cosmic; 1046945 DR Cosmic; 1047714 DR Cosmic; 1092606 DR Cosmic; 1136373 DR Cosmic; 1175831 DR Cosmic; 1176633 DR Cosmic; 1218873 DR Cosmic; 1235086 DR Cosmic; 1287921 DR Cosmic; 1289390 DR Cosmic; 1305385 DR Cosmic; 1312371 DR Cosmic; 1430343 DR Cosmic; 1473054 DR Cosmic; 1518105 DR Cosmic; 1603214 DR Cosmic; 1609463 DR Cosmic; 1998448 DR Cosmic; 2009515 DR Cosmic; 2164996 DR Cosmic; 2301525 DR Cosmic; 2560243 DR Cosmic; 2668302 DR Cosmic-CLP; 905957 DR DepMap; ACH-000148 DR DSMZ; ACC-781 DR DSMZCellDive; ACC-781 DR ECACC; 86082104 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 905957 DR GEO; GSM2113 DR GEO; GSM50182 DR GEO; GSM50246 DR GEO; GSM217581 DR GEO; GSM219968 DR GEO; GSM344346 DR GEO; GSM344396 DR GEO; GSM421868 DR GEO; GSM750776 DR GEO; GSM783962 DR GEO; GSM799319 DR GEO; GSM799382 DR GEO; GSM839032 DR GEO; GSM844563 DR GEO; GSM844564 DR GEO; GSM844565 DR GEO; GSM846359 DR GEO; GSM847392 DR GEO; GSM847488 DR GEO; GSM887098 DR GEO; GSM888169 DR GEO; GSM1008903 DR GEO; GSM1053700 DR GEO; GSM1153388 DR GEO; GSM1172877 DR GEO; GSM1181262 DR GEO; GSM1181319 DR GEO; GSM1214564 DR GEO; GSM1238131 DR GEO; GSM1374549 DR GEO; GSM1374550 DR GEO; GSM1669895 DR GEO; GSM1833625 DR GEO; GSM2124656 DR IARC_TP53; 579 DR IBRC; C10150 DR ICLC; HTL00007 DR KCB; KCB 2012025YJ DR KCLB; 30126 DR LiGeA; CCLE_743 DR LINCS_HMS; 50238 DR LINCS_LDP; LCL-1315 DR Lonza; 1444 DR NCI-DTP; HS 578T DR PharmacoDB; Hs578T_614_2019 DR PRIDE; PXD005292 DR PRIDE; PXD005942 DR PRIDE; PXD005946 DR PRIDE; PXD008222 DR PRIDE; PXD030304 DR Progenetix; CVCL_0332 DR PubChem_Cell_line; CVCL_0332 DR SKY/M-FISH/CGH; 2663 DR SLKBase; 3558 DR Wikidata; Q54895774 RX DOI=10.1016/B978-0-12-333530-2.50009-5; RX DOI=10.25904/1912/1434; RX DOI=10.4172/2157-7145.S2-005; RX PubMed=283258; RX PubMed=761205; RX PubMed=864756; RX PubMed=1961733; RX PubMed=3335022; RX PubMed=7902062; RX PubMed=9331090; RX PubMed=10700174; RX PubMed=10969801; RX PubMed=15153330; RX PubMed=15677628; RX PubMed=15748285; RX PubMed=16142302; RX PubMed=16397213; RX PubMed=16541312; RX PubMed=16959974; RX PubMed=17088437; RX PubMed=17157791; RX PubMed=17932254; RX PubMed=18277095; RX PubMed=18386134; RX PubMed=18516279; RX PubMed=19372543; RX PubMed=19582160; RX PubMed=19593635; RX PubMed=20070913; RX PubMed=20164919; RX PubMed=21778573; RX PubMed=22068913; RX PubMed=22347499; RX PubMed=22384151; RX PubMed=22460905; RX PubMed=22585861; RX PubMed=22628656; RX PubMed=23151021; RX PubMed=23601657; RX PubMed=23856246; RX PubMed=23933261; RX PubMed=24009699; RX PubMed=24094812; RX PubMed=24162158; RX PubMed=24176112; RX PubMed=24279929; RX PubMed=24670534; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25892236; RX PubMed=25960936; RX PubMed=26589293; RX PubMed=27377824; RX PubMed=27397505; RX PubMed=27807467; RX PubMed=28196595; RX PubMed=28287265; RX PubMed=28889351; RX PubMed=29671673; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; RX PubMed=38861359; WW Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/morphology-and-growth-of-atcc-htb-126 WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm WW Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=3 WW Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255 WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-305.html WW Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/breast-cancer-xenograft/hs578t-xenograft-model/ CC Group: Triple negative breast cancer (TNBC) cell line. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: JWGray breast cancer cell line panel. CC Part of: KuDOS 95 cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). CC Part of: NCI-60 cancer cell line panel. CC Population: Caucasian. CC Doubling time: 34 hours (PubMed=18386134); ~48 hours (DSMZ=ACC-781); 53.8 hours (NCI-DTP=HS 578T); 32.35 hours (JWGray panel). CC HLA typing: A*03,24; B*35,40; C*03:04:01,04; DPB1*04:01,78:01; DQB1*05:01:01,06:02; DRB1*01,15:01:01 (PubMed=15748285). CC HLA typing: A*03:01,24:02; B*35:03,40:01; C*03:04,04:01; DQA1*03:02,03:02 (PubMed=25960936). CC HLA typing: A*03:01,24:02; B*35:03,40:01; C*03:04,04:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=19593635). CC Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012612; Zygosity=Heterozygous (PubMed=17088437; PubMed=19593635; PubMed=28889351). CC Sequence variation: Mutation; HGNC; HGNC:7427; MT-CYB; Simple; p.Ala125Thr (m.15119G>A); ClinVar=VCV000693829; Zygosity=Homoplasmic (PubMed=29671673). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val157Phe (c.469G>T); ClinVar=VCV000012353; Zygosity=Homozygous (PubMed=1961733; PubMed=16541312; PubMed=17088437; PubMed=18277095; PubMed=28889351). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Mitochondrial genome sequencing. CC Omics: Genomics; Whole exome sequencing. CC Omics: Glycomics; N-glycan profiling. CC Omics: Metabolomics. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Phenotyping; Fluorescent probe library screening. CC Omics: Proteomics. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; PTM; Glycoproteome. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; lncRNA profiling; RT-qPCR platform. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.53%; Native American=0%; East Asian, North=1.71%; East Asian, South=0%; South Asian=0%; European, North=63.73%; European, South=34.01% (PubMed=30894373). CC Misspelling: HS758T; Cosmic=904372. CC Misspelling: Hs-587-T; Cosmic=1010929; Cosmic=1176633. CC Misspelling: HTB126; Note=Based on the ATCC catalog number. CC Discontinued: ATCC; CRL-7849; true. CC Derived from site: In situ; Breast; UBERON=UBERON_0000310. ST Source(s): ATCC=HTB-126; CCRID; Cosmic-CLP=905957; DSMZ=ACC-781; ECACC=86082104; KCLB=30126; DOI=10.4172/2157-7145.S2-005; PubMed=19372543; PubMed=25877200; PubMed=28889351; Technion Genomics Center ST Amelogenin: X ST CSF1PO: 13 ST D10S1248: 16 ST D12S391: 19 ST D13S317: 11 ST D16S539: 9,12 (ATCC=HTB-126; CCRID; Cosmic-CLP=905957; ECACC=86082104; KCLB=30126; DOI=10.4172/2157-7145.S2-005; PubMed=19372543; PubMed=25877200; PubMed=28889351; Technion Genomics Center) ST D16S539: 12 (DSMZ=ACC-781) ST D18S51: 16 ST D19S433: 14,15 ST D1S1656: 11,16 ST D21S11: 29,32.2 (ATCC=HTB-126; CCRID; DSMZ=ACC-781; DOI=10.4172/2157-7145.S2-005; PubMed=19372543; PubMed=25877200; Technion Genomics Center) ST D21S11: 32.2 (PubMed=28889351) ST D22S1045: 15,16 ST D2S1338: 17,26 ST D2S441: 14 ST D3S1358: 16,17 ST D5S818: 11 ST D6S1043: 12 ST D7S820: 10 ST D8S1179: 13 ST FGA: 23,24 ST Penta D: 8,13 ST Penta E: 13,14 ST TH01: 9,9.3 ST TPOX: 8 ST vWA: 17 DI NCIt; C4194; Invasive breast carcinoma of no special type OX NCBI_TaxID=9606; ! Homo sapiens (Human) OI CVCL_S253 ! Hs 578.Mg OI CVCL_0807 ! Hs 578Bst SX Female AG 74Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 51 // RX DOI=10.1016/B978-0-12-333530-2.50009-5; RA Leibovitz A.; RT "Cell lines from human breast."; RL (In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York; USA (1994). // RX DOI=10.25904/1912/1434; RA Morrison B.J.; RT "Breast cancer stem cells: tumourspheres and implications for therapy."; RL Thesis PhD (2010); Griffith University; Brisbane; Australia. // RX DOI=10.4172/2157-7145.S2-005; RA Fang R.-X., Shewale J.G., Nguyen V.T., Cardoso H., Swerdel M.R., RA Hart R.P., Furtado M.R.; RT "STR profiling of human cell lines: challenges and possible solutions RT to the growing problem."; RL J. Forensic Res. 2 Suppl. 2:5-5(2011). // RX PubMed=283258; DOI=10.1093/jnci/62.2.225; RA Smith H.S.; RT "In vitro properties of epithelial cell lines established from human RT carcinomas and nonmalignant tissue."; RL J. Natl. Cancer Inst. 62:225-230(1979). // RX PubMed=761205; RA Smith H.S., Springer E.L., Hackett A.J.; RT "Nuclear ultrastructure of epithelial cell lines derived from human RT carcinomas and nonmalignant tissues."; RL Cancer Res. 39:332-344(1979). // RX PubMed=864756; DOI=10.1093/jnci/58.6.1795; RA Hackett A.J., Smith H.S., Springer E.L., Owens R.B., Nelson-Rees W.A., RA Riggs J.L., Gardner M.B.; RT "Two syngeneic cell lines from human breast tissue: the aneuploid RT mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) RT cell lines."; RL J. Natl. Cancer Inst. 58:1795-1806(1977). // RX PubMed=1961733; DOI=10.1073/pnas.88.23.10657; PMCID=PMC52989; RA Runnebaum I.B., Nagarajan M., Bowman M., Soto D., Sukumar S.; RT "Mutations in p53 as potential molecular markers for human breast RT cancer."; RL Proc. Natl. Acad. Sci. U.S.A. 88:10657-10661(1991). // RX PubMed=3335022; RA Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., RA Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.; RT "Feasibility of drug screening with panels of human tumor cell lines RT using a microculture tetrazolium assay."; RL Cancer Res. 48:589-601(1988). // RX PubMed=7902062; RA de la Torre M., Hao X.-Y., Larsson R., Nygren P., Tsuruo T., RA Mannervik B., Bergh J.; RT "Characterization of four doxorubicin adapted human breast cancer cell RT lines with respect to chemotherapeutic drug sensitivity, drug RT resistance associated membrane proteins and glutathione RT transferases."; RL Anticancer Res. 13:1425-1430(1993). // RX PubMed=9331090; RA O'Connor P.M., Jackman J., Bae I., Myers T.G., Fan S.-J., Mutoh M., RA Scudiero D.A., Monks A., Sausville E.A., Weinstein J.N., Friend S.H., RA Fornace A.J. Jr., Kohn K.W.; RT "Characterization of the p53 tumor suppressor pathway in cell lines of RT the National Cancer Institute anticancer drug screen and correlations RT with the growth-inhibitory potency of 123 anticancer agents."; RL Cancer Res. 57:4285-4300(1997). // RX PubMed=10700174; DOI=10.1038/73432; RA Ross D.T., Scherf U., Eisen M.B., Perou C.M., Rees C., Spellman P.T., RA Iyer V.R., Jeffrey S.S., van de Rijn M., Waltham M.C., Pergamenschikov A., RA Lee J.C.F., Lashkari D., Shalon D., Myers T.G., Weinstein J.N., RA Botstein D., Brown P.O.; RT "Systematic variation in gene expression patterns in human cancer cell RT lines."; RL Nat. Genet. 24:227-235(2000). // RX PubMed=10969801; RA Forozan F., Mahlamaki E.H., Monni O., Chen Y.-D., Veldman R., Jiang Y., RA Gooden G.C., Ethier S.P., Kallioniemi A.H., Kallioniemi O.-P.; RT "Comparative genomic hybridization analysis of 38 breast cancer cell RT lines: a basis for interpreting complementary DNA microarray data."; RL Cancer Res. 60:4519-4525(2000). // RX PubMed=15153330; DOI=10.1593/neo.3292; PMCID=PMC1502105; RA Watts G.S., Oshiro M.M., Junk D.J., Wozniak R.J., Watterson S.J., RA Domann F.E., Futscher B.W.; RT "The acetyltransferase p300/CBP-associated factor is a p53 target gene RT in breast tumor cells."; RL Neoplasia 6:187-194(2004). // RX PubMed=15677628; DOI=10.1093/carcin/bgi032; RA Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C., RA Edwards P.A.W., Caldas C.; RT "Evidence that both genetic instability and selection contribute to RT the accumulation of chromosome alterations in cancer."; RL Carcinogenesis 26:923-930(2005). // RX PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742; RA Adams S., Robbins F.-M., Chen D., Wagage D., Holbeck S.L., RA Morse H.C. 3rd, Stroncek D., Marincola F.M.; RT "HLA class I and II genotype of the NCI-60 cell lines."; RL J. Transl. Med. 3:11.1-11.8(2005). // RX PubMed=16142302; DOI=10.3892/ijo.27.4.881; RA de Longueville F., Lacroix M., Barbuto A.-M., Bertholet V., Gallo D., RA Larsimont D., Marcq L., Zammatteo N., Boffe S., Leclercq G., RA Remacle J.; RT "Molecular characterization of breast cancer cell lines by a RT low-density microarray."; RL Int. J. Oncol. 27:881-892(2005). // RX PubMed=16397213; DOI=10.1158/0008-5472.CAN-05-2853; RA Elstrodt F., Hollestelle A., Nagel J.H.A., Gorin M., Wasielewski M., RA van den Ouweland A.M.W., Merajver S.D., Ethier S.P., Schutte M.; RT "BRCA1 mutation analysis of 41 human breast cancer cell lines reveals RT three new deleterious mutants."; RL Cancer Res. 66:41-45(2006). // RX PubMed=16541312; DOI=10.1007/s10549-006-9186-z; RA Wasielewski M., Elstrodt F., Klijn J.G.M., Berns E.M.J.J., Schutte M.; RT "Thirteen new p53 gene mutants identified among 41 human breast cancer RT cell lines."; RL Breast Cancer Res. Treat. 99:97-101(2006). // RX PubMed=16959974; DOI=10.1126/science.1133427; RA Sjoblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., RA Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., RA Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J.E., RA Dawson D., Willson J.K.V., Gazdar A.F., Hartigan J., Wu L., Liu C.-S., RA Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., RA Vogelstein B., Kinzler K.W., Velculescu V.E.; RT "The consensus coding sequences of human breast and colorectal RT cancers."; RL Science 314:268-274(2006). // RX PubMed=17088437; DOI=10.1158/1535-7163.MCT-06-0433; PMCID=PMC2705832; RA Ikediobi O.N., Davies H.R., Bignell G.R., Edkins S., Stevens C., RA O'Meara S., Santarius T., Avis T., Barthorpe S., Brackenbury L., RA Buck G., Butler A.P., Clements J., Cole J., Dicks E., Forbes S., RA Gray K., Halliday K., Harrison R., Hills K., Hinton J., Hunter C., RA Jenkinson A., Jones D., Kosmidou V., Lugg R., Menzies A., RA Mironenko T., Parker A., Perry J., Raine K.M., Richardson D., RA Shepherd R., Small A., Smith R., Solomon H., Stephens P.J., RA Teague J.W., Tofts C., Varian J., Webb T., West S., Widaa S., Yates A., RA Reinhold W.C., Weinstein J.N., Stratton M.R., Futreal P.A., Wooster R.; RT "Mutation analysis of 24 known cancer genes in the NCI-60 cell line RT set."; RL Mol. Cancer Ther. 5:2606-2612(2006). // RX PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521; RA Neve R.M., Chin K., Fridlyand J., Yeh J., Baehner F.L., Fevr T., RA Clark L., Bayani N., Coppe J.-P., Tong F., Speed T., Spellman P.T., RA DeVries S., Lapuk A., Wang N.J., Kuo W.-L., Stilwell J.L., Pinkel D., RA Albertson D.G., Waldman F.M., McCormick F., Dickson R.B., RA Johnson M.D., Lippman M.E., Ethier S.P., Gazdar A.F., Gray J.W.; RT "A collection of breast cancer cell lines for the study of RT functionally distinct cancer subtypes."; RL Cancer Cell 10:515-527(2006). // RX PubMed=17932254; DOI=10.1126/science.1145720; RA Wood L.D., Parsons D.W., Jones S., Lin J., Sjoblom T., Leary R.J., RA Shen D., Boca S.M., Barber T.D., Ptak J., Silliman N., Szabo S., RA Dezso Z., Ustyanksky V., Nikolskaya T., Nikolsky Y., Karchin R., RA Wilson P.A., Kaminker J.S., Zhang Z.-M., Croshaw R., Willis J.E., RA Dawson D., Shipitsin M., Willson J.K.V., Sukumar S., Polyak K., RA Park B.H., Pethiyagoda C.L., Pant P.V.K., Ballinger D.G., Sparks A.B., RA Hartigan J., Smith D.R., Suh E., Papadopoulos N., Buckhaults P., RA Markowitz S.D., Parmigiani G., Kinzler K.W., Velculescu V.E., RA Vogelstein B.; RT "The genomic landscapes of human breast and colorectal cancers."; RL Science 318:1108-1113(2007). // RX PubMed=18277095; DOI=10.4161/cbt.7.5.5712; RA Berglind H., Pawitan Y., Kato S., Ishioka C., Soussi T.; RT "Analysis of p53 mutation status in human cancer cell lines: a RT paradigm for cell line cross-contamination."; RL Cancer Biol. Ther. 7:699-708(2008). // RX PubMed=18386134; DOI=10.1007/s10585-008-9169-z; RA Hughes L., Malone C., Chumsri S., Burger A.M., McDonnell S.; RT "Characterisation of breast cancer cell lines and establishment of a RT novel isogenic subclone to study migration, invasion and RT tumourigenicity."; RL Clin. Exp. Metastasis 25:549-557(2008). // RX PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004; PMCID=PMC2391005; RA Kenny P.A., Lee G.Y., Myers C.A., Neve R.M., Semeiks J.R., RA Spellman P.T., Lorenz K., Lee E.H., Barcellos-Hoff M.H., RA Petersen O.W., Gray J.W., Bissell M.J.; RT "The morphologies of breast cancer cell lines in three-dimensional RT assays correlate with their profiles of gene expression."; RL Mol. Oncol. 1:84-96(2007). // RX PubMed=19372543; DOI=10.1158/1535-7163.MCT-08-0921; PMCID=PMC4020356; RA Lorenzi P.L., Reinhold W.C., Varma S., Hutchinson A.A., Pommier Y., RA Chanock S.J., Weinstein J.N.; RT "DNA fingerprinting of the NCI-60 cell line panel."; RL Mol. Cancer Ther. 8:713-724(2009). // RX PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084; RA Kao J., Salari K., Bocanegra M., Choi Y.-L., Girard L., Gandhi J., RA Kwei K.A., Hernandez-Boussard T., Wang P., Gazdar A.F., Minna J.D., RA Pollack J.R.; RT "Molecular profiling of breast cancer cell lines defines relevant RT tumor models and provides a resource for cancer gene discovery."; RL PLoS ONE 4:e6146.1-e6146.16(2009). // RX PubMed=19593635; DOI=10.1007/s10549-009-0460-8; RA Hollestelle A., Nagel J.H.A., Smid M., Lam S., Elstrodt F., RA Wasielewski M., Ng S.S., French P.J., Peeters J.K., Rozendaal M.J., RA Riaz M., Koopman D.G., ten Hagen T.L.M., de Leeuw B.H.C.G.M., RA Zwarthoff E.C., Teunisse A.F.A.S., van der Spek P.J., Klijn J.G.M., RA Dinjens W.N.M., Ethier S.P., Clevers H.C., Jochemsen A.G., RA den Bakker M.A., Foekens J.A., Martens J.W.M., Schutte M.; RT "Distinct gene mutation profiles among luminal-type and basal-type RT breast cancer cell lines."; RL Breast Cancer Res. Treat. 121:53-64(2010). // RX PubMed=20070913; DOI=10.1186/1471-2407-10-15; PMCID=PMC2836299; RA Tsuji K., Kawauchi S., Saito S., Furuya T., Ikemoto K., Nakao M., RA Yamamoto S., Oka M., Hirano T., Sasaki K.; RT "Breast cancer cell lines carry cell line-specific genomic alterations RT that are distinct from aberrations in breast cancer tissues: RT comparison of the CGH profiles between cancer cell lines and primary RT cancer tissues."; RL BMC Cancer 10:15.1-15.10(2010). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., RA Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., RA Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., RA Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.; RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=21778573; DOI=10.3233/BD-2010-0307; PMCID=PMC3532890; RA Chavez K.J., Garimella S.V., Lipkowitz S.; RT "Triple negative breast cancer cell lines: one tool in the search for RT better treatment of triple negative breast cancer."; RL Breast Dis. 32:35-48(2010). // RX PubMed=22068913; DOI=10.1073/pnas.1111840108; PMCID=PMC3219108; RA Gillet J.-P., Calcagno A.M., Varma S., Marino M., Green L.J., RA Vora M.I., Patel C., Orina J.N., Eliseeva T.A., Singal V., RA Padmanabhan R., Davidson B., Ganapathi R., Sood A.K., Rueda B.R., RA Ambudkar S.V., Gottesman M.M.; RT "Redefining the relevance of established cancer cell lines to the RT study of mechanisms of clinical anti-cancer drug resistance."; RL Proc. Natl. Acad. Sci. 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Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., RA Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., RA Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., RA Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., RA Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., RA Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.; RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396; RA Marcotte R., Brown K.R., Suarez Saiz F.J., Sayad A., Karamboulas K., RA Krzyzanowski P.M., Sircoulomb F., Medrano M., Fedyshyn Y., Koh J.L.-Y., RA van Dyk D., Fedyshyn B., Luhova M., Brito G.C., Vizeacoumar F.J., RA Vizeacoumar F.S., Datti A., Kasimer D., Buzina A., Mero P., RA Misquitta C., Normand J., Haider M., Ketela T., Wrana J.L., RA Rottapel R., Neel B.G., Moffat J.; RT "Essential gene profiles in breast, pancreatic, and ovarian cancer RT cells."; RL Cancer Discov. 2:172-189(2012). // RX PubMed=22628656; DOI=10.1126/science.1218595; PMCID=PMC3526189; RA Jain M., Nilsson R., Sharma S., Madhusudhan N., Kitami T., Souza A.L., RA Kafri R., Kirschner M.W., Clish C.B., Mootha V.K.; RT "Metabolite profiling identifies a key role for glycine in rapid RT cancer cell proliferation."; RL Science 336:1040-1044(2012). // RX PubMed=23151021; DOI=10.1186/1471-2164-13-619; PMCID=PMC3546428; RA Grigoriadis A., Mackay A., Noel E., Wu P.-J., Natrajan R., Frankum J., RA Reis-Filho J.S., Tutt A.; RT "Molecular characterisation of cell line models for triple-negative RT breast cancers."; RL BMC Genomics 13:619.1-619.14(2012). // RX PubMed=23601657; DOI=10.1186/bcr3415; PMCID=PMC3672661; RA Riaz M., van Jaarsveld M.T.M., Hollestelle A., RA Prager-van der Smissen W.J.C., Heine A.A.J., Boersma A.W.M., Liu J.-J., RA Helmijr J.C.A., Ozturk B., Smid M., Wiemer E.A.C., Foekens J.A., RA Martens J.W.M.; RT "miRNA expression profiling of 51 human breast cancer cell lines RT reveals subtype and driver mutation-specific miRNAs."; RL Breast Cancer Res. 15:R33.1-R33.17(2013). // RX PubMed=23856246; DOI=10.1158/0008-5472.CAN-12-3342; PMCID=PMC4893961; RA Abaan O.D., Polley E.C., Davis S.R., Zhu Y.-L.J., Bilke S., Walker R.L., RA Pineda M.A., Gindin Y., Jiang Y., Reinhold W.C., Holbeck S.L., RA Simon R.M., Doroshow J.H., Pommier Y., Meltzer P.S.; RT "The exomes of the NCI-60 panel: a genomic resource for cancer biology RT and systems pharmacology."; RL Cancer Res. 73:4372-4382(2013). // RX PubMed=23933261; DOI=10.1016/j.celrep.2013.07.018; RA Moghaddas Gholami A., Hahne H., Wu Z.-X., Auer F.J., Meng C., RA Wilhelm M., Kuster B.; RT "Global proteome analysis of the NCI-60 cell line panel."; RL Cell Rep. 4:609-620(2013). // RX PubMed=24009699; DOI=10.1371/journal.pone.0072704; PMCID=PMC3751845; RA Liu X., Nie H., Zhang Y.-B., Yao Y.-F., Maitikabili A., Qu Y.-P., RA Shi S.-L., Chen C.-Y., Li Y.; RT "Cell surface-specific N-glycan profiling in breast cancer."; RL PLoS ONE 8:e72704.1-e72704.11(2013). // RX PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310; RA Timmerman L.A., Holton T., Yuneva M., Louie R.J., Padro M., Daemen A., RA Hu M., Chan D.A., Ethier S.P., van 't Veer L.J., Polyak K., RA McCormick F., Gray J.W.; RT "Glutamine sensitivity analysis identifies the xCT antiporter as a RT common triple-negative breast tumor therapeutic target."; RL Cancer Cell 24:450-465(2013). // RX PubMed=24162158; DOI=10.1007/s10549-013-2743-3; PMCID=PMC3832776; RA Prat A., Karginova O., Parker J.S., Fan C., He X.-P., Bixby L.M., RA Harrell J.C., Roman E., Adamo B., Troester M.A., Perou C.M.; RT "Characterization of cell lines derived from breast cancers and normal RT mammary tissues for the study of the intrinsic molecular subtypes."; RL Breast Cancer Res. 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