ID   HT-1080
AC   CVCL_0317
SY   Ht-1080; HT 1080; HT1080; HT 1080.T
DR   BTO; BTO_0001282
DR   CLO; CLO_0004266
DR   CLO; CLO_0004276
DR   EFO; EFO_0002059
DR   MCCL; MCC:0000210
DR   CLDB; cl1735
DR   CLDB; cl1736
DR   CLDB; cl1737
DR   CLDB; cl1738
DR   CLDB; cl1740
DR   CLDB; cl1741
DR   CLDB; cl1742
DR   CLDB; cl4913
DR   ABM; T8971
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CCL-121
DR   ATCC; CRL-7951
DR   BCRC; 60037
DR   BCRJ; 0110
DR   BioGRID_ORCS_Cell_line; 279
DR   BioSample; SAMN01821563
DR   BioSample; SAMN01821634
DR   BioSample; SAMN01821685
DR   BioSample; SAMN01821731
DR   BioSample; SAMN03471913
DR   BioSample; SAMN10987635
DR   cancercelllines; CVCL_0317
DR   CCRID; 1101HUM-PUMC000070
DR   CCRID; 3101HUMTCHu170
DR   CCRID; 4201HUM-CCTCC00105
DR   CCTCC; GDC0105
DR   Cell_Model_Passport; SIDM00828
DR   ChEMBL-Cells; CHEMBL3308396
DR   ChEMBL-Targets; CHEMBL614580
DR   CLS; 300216
DR   Cosmic; 716177
DR   Cosmic; 716188
DR   Cosmic; 724819
DR   Cosmic; 907064
DR   Cosmic; 912000
DR   Cosmic; 1045409
DR   Cosmic; 1067221
DR   Cosmic; 1933190
DR   Cosmic; 2009505
DR   Cosmic; 2301553
DR   Cosmic; 2307731
DR   Cosmic; 2560245
DR   Cosmic; 2764533
DR   Cosmic-CLP; 907064
DR   DepMap; ACH-000054
DR   DSMZ; ACC-315
DR   DSMZCellDive; ACC-315
DR   ECACC; 85111505
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   ENCODE; ENCBS039VHD
DR   ENCODE; ENCBS225AAA
DR   ENCODE; ENCBS512AAA
DR   ENCODE; ENCBS513AAA
DR   ENCODE; ENCBS617SGR
DR   ENCODE; ENCBS688VJF
DR   ENCODE; ENCBS798NML
DR   ENCODE; ENCBS816VMN
DR   ENCODE; ENCBS937RAY
DR   FANTOM5_SSTAR; 10758-110E2
DR   GDSC; 907064
DR   GEO; GSM185089
DR   GEO; GSM185090
DR   GEO; GSM256074
DR   GEO; GSM256075
DR   GEO; GSM256076
DR   GEO; GSM256077
DR   GEO; GSM256078
DR   GEO; GSM256079
DR   GEO; GSM256080
DR   GEO; GSM256081
DR   GEO; GSM256082
DR   GEO; GSM256083
DR   GEO; GSM256084
DR   GEO; GSM256085
DR   GEO; GSM256086
DR   GEO; GSM256087
DR   GEO; GSM256088
DR   GEO; GSM256089
DR   GEO; GSM256090
DR   GEO; GSM256091
DR   GEO; GSM256092
DR   GEO; GSM256093
DR   GEO; GSM256094
DR   GEO; GSM256095
DR   GEO; GSM256096
DR   GEO; GSM256097
DR   GEO; GSM256098
DR   GEO; GSM256099
DR   GEO; GSM256100
DR   GEO; GSM256101
DR   GEO; GSM256102
DR   GEO; GSM256103
DR   GEO; GSM256104
DR   GEO; GSM256105
DR   GEO; GSM256106
DR   GEO; GSM256107
DR   GEO; GSM256108
DR   GEO; GSM256109
DR   GEO; GSM256110
DR   GEO; GSM256111
DR   GEO; GSM256112
DR   GEO; GSM256113
DR   GEO; GSM256114
DR   GEO; GSM827307
DR   GEO; GSM887136
DR   GEO; GSM888207
DR   GEO; GSM1669908
DR   GEO; GSM1676302
DR   GEO; GSM1701637
DR   GEO; GSM3585511
DR   GEO; GSM3585512
DR   GEO; GSM3585513
DR   GEO; GSM3585514
DR   IARC_TP53; 21378
DR   IBRC; C10104
DR   ICLC; HTL98016
DR   IGRhCellID; HT1080
DR   IZSLER; BS TCL 27
DR   JCRB; IFO50354
DR   JCRB; JCRB9113
DR   KCB; KCB 2013029YJ
DR   KCLB; 10121
DR   LiGeA; CCLE_463
DR   LINCS_LDP; LCL-1435
DR   Lonza; 744
DR   NCBI_Iran; C437
DR   PharmacoDB; HT1080_625_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0317
DR   PubChem_Cell_line; CVCL_0317
DR   RCB; RCB1956
DR   TKG; TKG 0202
DR   TOKU-E; 1963
DR   Wikidata; Q5636047
RX   CelloPub=CLPUB00698;
RX   PubMed=375235;
RX   PubMed=3335022;
RX   PubMed=3413074;
RX   PubMed=3558490;
RX   PubMed=3986962;
RX   PubMed=4132053;
RX   PubMed=6538202;
RX   PubMed=6652615;
RX   PubMed=11416159;
RX   PubMed=11668190;
RX   PubMed=12068308;
RX   PubMed=17254797;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=22282976;
RX   PubMed=22460905;
RX   PubMed=24726063;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=26351324;
RX   PubMed=26368816;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31978347;
RX   PubMed=35839778;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-124.html
WW   Info; Wikipedia; -; https://en.wikipedia.org/wiki/HT1080
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/sarcoma-xenograft/ht1080-xenograft-model/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: ENCODE project common cell types; tier 3.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Population: Caucasian.
CC   Doubling time: 26 hours (PubMed=4132053); ~30 hours (DSMZ=ACC-315).
CC   HLA typing: A*31:01,68:01; B*27:05,27:05; C*02:02,02:02 (PubMed=26589293).
CC   HLA typing: A*31:01:02,68:01:01; B*27:05:02; C*02:02:02; DPB1*03:01,04:01; DQA1*03:03:01,05:01:01; DQB1*02:01:01,03:01:01; DRB1*03:01:01,04:07:01 (CLS=300216).
CC   HLA typing: A*31:01:02,68:01:01; B*27:05:02,27:05:02; C*02:02:02,02:02:02; DPA1*01:03:01,01:03:01; DPB1*04:01:01,04:01:01; DRA*01:01:01,01:02:02 (DSMZCellDive=ACC-315).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (ATCC=CCL-121).
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (PubMed=26368816).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=12068308; ATCC=CCL-121; Cosmic-CLP=907064; DepMap=ACH-000054).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0.86%; Native American=0.35%; East Asian, North=1.36%; East Asian, South=0.29%; South Asian=0%; European, North=68.21%; European, South=28.94% (PubMed=30894373).
CC   Misspelling: HT1180; Note=Occasionally.
CC   Discontinued: ATCC; CRL-7951; true.
CC   Discontinued: RCB; RCB1956; true.
CC   Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
ST   Source(s): ATCC=CCL-121; CCRID; CLS=300216; Cosmic-CLP=907064; DSMZ=ACC-315; ECACC=85111505; JCRB=IFO50354; JCRB=JCRB9113; KCLB=10121; CelloPub=CLPUB00698; PubMed=11416159; PubMed=17254797; PubMed=25877200; RCB=RCB1956; Technion Genomics Center
ST   Amelogenin: X,Y
ST   CSF1PO: 11 (PubMed=17254797)
ST   CSF1PO: 12 (ATCC=CCL-121; CCRID; CLS=300216; Cosmic-CLP=907064; DSMZ=ACC-315; ECACC=85111505; JCRB=IFO50354; JCRB=JCRB9113; KCLB=10121; PubMed=25877200; RCB=RCB1956; Technion Genomics Center)
ST   D10S1248: 13,15
ST   D12S391: 20,22
ST   D13S317: 12,14
ST   D16S539: 9,12
ST   D18S51: 12,18
ST   D19S433: 13.2,15 (CCRID; Technion Genomics Center)
ST   D19S433: 14,15 (DSMZ=ACC-315)
ST   D1S1656: 16,17.3
ST   D21S11: 28,30
ST   D22S1045: 11,16
ST   D2S1338: 25,26
ST   D2S441: 10,14
ST   D3S1358: 16
ST   D5S818: 11,13
ST   D7S820: 9,10
ST   D8S1179: 13,14
ST   DYS391: 10
ST   FGA: 22,25
ST   Penta D: 9,12
ST   Penta E: 5,15
ST   TH01: 6
ST   TPOX: 8
ST   vWA: 14,19
DI   NCIt; C3043; Fibrosarcoma
DI   ORDO; Orphanet_2030; Fibrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 50
//
RX   CelloPub=CLPUB00698;
RA   van Bokhoven, Adrie
RT   "Models for prostate cancer. Molecular characterization and critical
RT   appraisal of human prostate carcinoma cell lines.";
RL   Thesis PhD (2004); Katholieke Universiteit Nijmegen; Nijmegen; Netherlands.
//
RX   PubMed=375235; DOI=10.1073/pnas.76.3.1288; PMCID=PMC383236;
RA   Sherwin, Stephen A.
RA   Sliski, Ann H.
RA   Todaro, George J.
RT   "Human melanoma cells have both nerve growth factor and nerve growth
RT   factor-specific receptors on their cell surfaces.";
RL   Proc. Natl. Acad. Sci. U.S.A. 76:1288-1292(1979).
//
RX   PubMed=3335022;
RA   Alley, Michael C.
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Hursey, Miriam L.
RA   Czerwinski, Maciej J.
RA   Fine, Donald L.
RA   Abbott, Betty Jane
RA   Mayo, Joseph G.
RA   Shoemaker, Robert H.
RA   Boyd, Michael R.
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=3413074; DOI=10.1073/pnas.85.16.6042; PMCID=PMC281901;
RA   Pereira-Smith, Olivia M.
RA   Smith, James R.
RT   "Genetic analysis of indefinite division in human cells:
RT   identification of four complementation groups.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:6042-6046(1988).
//
RX   PubMed=3558490; DOI=10.1002/jcp.1041300303;
RA   Gupta, Radhey Shyam
RA   Dudani, Anil Kumar
RT   "Species-specific differences in the toxicity of rhodamine 123 towards
RT   cultured mammalian cells.";
RL   J. Cell. Physiol. 130:321-327(1987).
//
RX   PubMed=3986962; DOI=10.1093/carcin/6.4.549;
RA   Watatani, Masahiro
RA   Ikenaga, Mituo
RA   Hatanaka, Toshihiro
RA   Kinuta, Masakatsu
RA   Takai, Shin-ichiro
RA   Mori, Takesada
RA   Kondo, Sohei
RT   "Analysis of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced DNA
RT   damage in tumor cell strains from Japanese patients and demonstration
RT   of MNNG hypersensitivity of Mer xenografts in athymic nude mice.";
RL   Carcinogenesis 6:549-553(1985).
//
RX   PubMed=4132053; DOI=10.1002/1097-0142(197404)33:4<1027::AID-CNCR2820330419>3.0.CO;2-Z;
RA   Rasheed, Suraiya
RA   Nelson-Rees, Walter Anthony
RA   Toth, Eva M.
RA   Arnstein, Paul
RA   Gardner, Murray B.
RT   "Characterization of a newly derived human sarcoma cell line (HT-1080).";
RL   Cancer 33:1027-1033(1974).
//
RX   PubMed=6538202; DOI=10.1083/jcb.98.3.1133; PMCID=PMC2113122;
RA   Azzarone, Bruno
RA   Suarez, Horacio Guillermo
RA   Mingari, Maria Cristina
RA   Moretta, Lorenzo
RA   Fauci, Anthony Stephen
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RT   fibroblasts of embryonic but not of adult origin.";
RL   J. Cell Biol. 98:1133-1137(1984).
//
RX   PubMed=6652615; DOI=10.1016/0165-4608(83)90092-4;
RA   Chen, Tchaw-Ren
RA   Hay, Robert J.
RA   Macy, Marvin L.
RT   "Intercellular karyotypic similarity in near-diploid cell lines of
RT   human tumor origins.";
RL   Cancer Genet. Cytogenet. 10:351-362(1983).
//
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RA   Masters, John R.W.
RA   Thomson, Jim A.
RA   Daly-Burns, Bernadette
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RA   Packer, Phil
RA   Toji, Lorraine H.
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RA   Tanabe, Hideyuki
RA   Arlett, Colin Francis
RA   Kelland, Lloyd R.
RA   Harrison, Maureen
RA   Virmani, Arvind K.
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RA   Debenham, Paul G.
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RT   standard for human cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
//
RX   PubMed=11668190; DOI=10.1177/002215540104901105;
RA   Quentmeier, Hilmar
RA   Osborn, Mary
RA   Reinhardt, Julia
RA   Zaborski, Margarete
RA   Drexler, Hans Gunther
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RT   tumors.";
RL   J. Histochem. Cytochem. 49:1369-1378(2001).
//
RX   PubMed=12068308; DOI=10.1038/nature00766;
RA   Davies, Helen R.
RA   Bignell, Graham Robert
RA   Cox, Charles
RA   Stephens, Philip J.
RA   Edkins, Sarah
RA   Clegg, Sheila
RA   Teague, Jon W.
RA   Woffendin, Hayley
RA   Garnett, Mathew J.
RA   Bottomley, William
RA   Davis, Neil
RA   Dicks, Ed
RA   Ewing, Rebecca
RA   Floyd, Yvonne
RA   Gray, Kristian
RA   Hall, Sarah
RA   Hawes, Rachel
RA   Hughes, Jaime
RA   Kosmidou, Vivian
RA   Menzies, Andrew
RA   Mould, Catherine
RA   Parker, Adrian
RA   Stevens, Claire
RA   Watt, Stephen
RA   Hooper, Steven
RA   Wilson, Rebecca
RA   Jayatilake, Hiran
RA   Gusterson, Barry Austin
RA   Cooper, Colin S.
RA   Shipley, Janet M.
RA   Hargrave, Darren
RA   Pritchard-Jones, Kathy
RA   Maitland, Norman J.
RA   Chenevix-Trench, Georgia
RA   Riggins, Gregory J.
RA   Bigner, Darell Doty
RA   Palmieri, Giuseppe
RA   Cossu, Antonio
RA   Flanagan, Adrienne M.
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RA   Ho, Judy W.C.
RA   Leung, Suet Yi
RA   Yuen, Siu Tsan
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RA   Darrow, Timothy L.
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RA   Marais, Richard
RA   Marshall, Christopher John
RA   Wooster, Richard
RA   Stratton, Michael Rudolf
RA   Futreal, P. Andrew
RT   "Mutations of the BRAF gene in human cancer.";
RL   Nature 417:949-954(2002).
//
RX   PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001;
RA   Azari, Shahram
RA   Ahmadi, Nahid
RA   Jeddi-Tehrani, Mahmood
RA   Shokri, Fazel
RT   "Profiling and authentication of human cell lines using short tandem
RT   repeat (STR) loci: report from the National Cell Bank of Iran.";
RL   Biologicals 35:195-202(2007).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
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RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
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RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=22282976; DOI=10.1093/carcin/1.1.21;
RA   Day, Rufus S. 3rd
RA   Ziolkowski, Chuck H.J.
RA   Scudiero, Dominic A.
RA   Meyer, Sharon A.
RA   Mattern, Michael R.
RT   "Human tumor cell strains defective in the repair of alkylation
RT   damage.";
RL   Carcinogenesis 1:21-32(1980).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
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RA   Morais, Paula
RA   Meltzer, Jodi
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RA   Thibault, Joseph
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RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
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RA   Palescandolo, Emanuele
RA   Gupta, Supriya
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RA   Sougnez, Carrie
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RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
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RA   Morrissey, Michael P.
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RA   Schlegel, Robert
RA   Garraway, Levi Alexander
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RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=24726063; DOI=10.1186/1756-9966-33-33; PMCID=PMC4022359;
RA   Koelsche, Christian
RA   Renner, Marcus
RA   Hartmann, Wolfgang
RA   Brandt, Regine
RA   Lehner, Burkhard
RA   Waldburger, Nina
RA   Alldinger, Ingo
RA   Schmitt, Thomas
RA   Egerer, Gerlinde
RA   Penzel, Roland
RA   Wardelmann, Eva
RA   Schirmacher, Peter
RA   von Deimling, Andreas
RA   Mechtersheimer, Gunhild
RT   "TERT promoter hotspot mutations are recurrent in myxoid liposarcomas
RT   but rare in other soft tissue sarcoma entities.";
RL   J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476;
RA   Teicher, Beverly A.
RA   Polley, Eric C.
RA   Kunkel, Mark W.
RA   Evans, David
RA   Silvers, Thomas E.
RA   Delosh, Rene M.
RA   Laudeman, Julie
RA   Ogle, Chad
RA   Reinhart, Russell
RA   Selby, Michael
RA   Connelly, John
RA   Harris, Erik
RA   Monks, Anne
RA   Morris, Joel
RT   "Sarcoma cell line screen of oncology drugs and investigational agents
RT   identifies patterns associated with gene and microRNA expression.";
RL   Mol. Cancer Ther. 14:2452-2462(2015).
//
RX   PubMed=26368816; DOI=10.1371/journal.pone.0133813; PMCID=PMC4569544;
RA   Li, Lu-Yuan
RA   Paz, Ana C.
RA   Wilky, Breelyn A.
RA   Johnson, Britt
RA   Galoian, Karina
RA   Rosenberg, Andrew
RA   Hu, Guo-Zhi
RA   Tinoco, Gabriel
RA   Bodamer, Olaf A.
RA   Trent, Jonathan C. 2nd
RT   "Treatment with a small molecule mutant IDH1 inhibitor suppresses
RT   tumorigenic activity and decreases production of the oncometabolite
RT   2-hydroxyglutarate in human chondrosarcoma cells.";
RL   PLoS ONE 10:e0133813.1-e0133813.19(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, A. Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254;
RA   Nusinow, David Paul
RA   Szpyt, John
RA   Ghandi, Mahmoud
RA   Rose, Christopher M.
RA   McDonald, E. Robert 3rd
RA   Kalocsay, Marian
RA   Jane-Valbuena, Judit
RA   Gelfand, Ellen T.
RA   Schweppe, Devin K.
RA   Jedrychowski, Mark P.
RA   Golji, Javad
RA   Porter, Dale A.
RA   Rejtar, Tomas
RA   Wang, Y. Karen
RA   Kryukov, Gregory V.
RA   Stegmeier, Frank
RA   Erickson, Brian K.
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RA   Gygi, Steven P.
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//