ID HT-1080 AC CVCL_0317 SY Ht-1080; HT 1080; HT1080; HT 1080.T DR BTO; BTO_0001282 DR CLO; CLO_0004266 DR CLO; CLO_0004276 DR EFO; EFO_0002059 DR MCCL; MCC:0000210 DR CLDB; cl1735 DR CLDB; cl1736 DR CLDB; cl1737 DR CLDB; cl1738 DR CLDB; cl1740 DR CLDB; cl1741 DR CLDB; cl1742 DR CLDB; cl4913 DR ABM; T8971 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; CCL-121 DR ATCC; CRL-7951 DR BCRC; 60037 DR BCRJ; 0110 DR BioGRID_ORCS_Cell_line; 279 DR BioSample; SAMN01821563 DR BioSample; SAMN01821634 DR BioSample; SAMN01821685 DR BioSample; SAMN01821731 DR BioSample; SAMN03471913 DR BioSample; SAMN10987635 DR cancercelllines; CVCL_0317 DR CCRID; 1101HUM-PUMC000070 DR CCRID; 3101HUMTCHu170 DR CCRID; 4201HUM-CCTCC00105 DR CCTCC; GDC0105 DR Cell_Model_Passport; SIDM00828 DR ChEMBL-Cells; CHEMBL3308396 DR ChEMBL-Targets; CHEMBL614580 DR CLS; 300216 DR Cosmic; 716177 DR Cosmic; 716188 DR Cosmic; 724819 DR Cosmic; 907064 DR Cosmic; 912000 DR Cosmic; 1045409 DR Cosmic; 1067221 DR Cosmic; 1933190 DR Cosmic; 2009505 DR Cosmic; 2301553 DR Cosmic; 2307731 DR Cosmic; 2560245 DR Cosmic; 2764533 DR Cosmic-CLP; 907064 DR DepMap; ACH-000054 DR DSMZ; ACC-315 DR DSMZCellDive; ACC-315 DR ECACC; 85111505 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR ENCODE; ENCBS039VHD DR ENCODE; ENCBS225AAA DR ENCODE; ENCBS512AAA DR ENCODE; ENCBS513AAA DR ENCODE; ENCBS617SGR DR ENCODE; ENCBS688VJF DR ENCODE; ENCBS798NML DR ENCODE; ENCBS816VMN DR ENCODE; ENCBS937RAY DR FANTOM5_SSTAR; 10758-110E2 DR GDSC; 907064 DR GEO; GSM185089 DR GEO; GSM185090 DR GEO; GSM256074 DR GEO; GSM256075 DR GEO; GSM256076 DR GEO; GSM256077 DR GEO; GSM256078 DR GEO; GSM256079 DR GEO; GSM256080 DR GEO; GSM256081 DR GEO; GSM256082 DR GEO; GSM256083 DR GEO; GSM256084 DR GEO; GSM256085 DR GEO; GSM256086 DR GEO; GSM256087 DR GEO; GSM256088 DR GEO; GSM256089 DR GEO; GSM256090 DR GEO; GSM256091 DR GEO; GSM256092 DR GEO; GSM256093 DR GEO; GSM256094 DR GEO; GSM256095 DR GEO; GSM256096 DR GEO; GSM256097 DR GEO; GSM256098 DR GEO; GSM256099 DR GEO; GSM256100 DR GEO; GSM256101 DR GEO; GSM256102 DR GEO; GSM256103 DR GEO; GSM256104 DR GEO; GSM256105 DR GEO; GSM256106 DR GEO; GSM256107 DR GEO; GSM256108 DR GEO; GSM256109 DR GEO; GSM256110 DR GEO; GSM256111 DR GEO; GSM256112 DR GEO; GSM256113 DR GEO; GSM256114 DR GEO; GSM827307 DR GEO; GSM887136 DR GEO; GSM888207 DR GEO; GSM1669908 DR GEO; GSM1676302 DR GEO; GSM1701637 DR GEO; GSM3585511 DR GEO; GSM3585512 DR GEO; GSM3585513 DR GEO; GSM3585514 DR IARC_TP53; 21378 DR IBRC; C10104 DR ICLC; HTL98016 DR IGRhCellID; HT1080 DR IZSLER; BS TCL 27 DR JCRB; IFO50354 DR JCRB; JCRB9113 DR KCB; KCB 2013029YJ DR KCLB; 10121 DR LiGeA; CCLE_463 DR LINCS_LDP; LCL-1435 DR Lonza; 744 DR NCBI_Iran; C437 DR PharmacoDB; HT1080_625_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_0317 DR PubChem_Cell_line; CVCL_0317 DR RCB; RCB1956 DR TKG; TKG 0202 DR TOKU-E; 1963 DR Wikidata; Q5636047 RX CelloPub=CLPUB00698; RX PubMed=375235; RX PubMed=3335022; RX PubMed=3413074; RX PubMed=3558490; RX PubMed=3986962; RX PubMed=4132053; RX PubMed=6304521; RX PubMed=6538202; RX PubMed=6652615; RX PubMed=11416159; RX PubMed=11668190; RX PubMed=12068308; RX PubMed=17254797; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=22282976; RX PubMed=22460905; RX PubMed=24726063; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=26351324; RX PubMed=26368816; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-124.html WW Info; Wikipedia; -; https://en.wikipedia.org/wiki/HT1080 WW Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/sarcoma-xenograft/ht1080-xenograft-model/ CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: ENCODE project common cell types; tier 3. CC Part of: MD Anderson Cell Lines Project. CC Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). CC Population: Caucasian. CC Doubling time: 26 hours (PubMed=4132053); ~30 hours (DSMZ=ACC-315). CC HLA typing: A*31:01,68:01; B*27:05,27:05; C*02:02,02:02 (PubMed=26589293). CC HLA typing: A*31:01:02,68:01:01; B*27:05:02; C*02:02:02; DPB1*03:01,04:01; DQA1*03:03:01,05:01:01; DQB1*02:01:01,03:01:01; DRB1*03:01:01,04:07:01 (CLS=300216). CC HLA typing: A*31:01:02,68:01:01; B*27:05:02,27:05:02; C*02:02:02,02:02:02; DPA1*01:03:01,01:03:01; DPB1*04:01:01,04:01:01; DRA*01:01:01,01:02:02 (DSMZCellDive=ACC-315). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (ATCC=CCL-121). CC Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (PubMed=26368816). CC Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=12068308; ATCC=CCL-121; Cosmic-CLP=907064; DepMap=ACH-000054). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.86%; Native American=0.35%; East Asian, North=1.36%; East Asian, South=0.29%; South Asian=0%; European, North=68.21%; European, South=28.94% (PubMed=30894373). CC Anecdotal: One of the 3 cell lines (HT-1080, RD and SK-N-SH) where the NRAS oncogene was first identified (PubMed=6304521). CC Caution: This cell line is considered by some researchers to represent a dedifferentiated chondrosarcoma due to the presence of an IDH1 mutation (PubMed=26368816). CC Misspelling: HT1180; Note=Occasionally. CC Discontinued: ATCC; CRL-7951; true. CC Discontinued: RCB; RCB1956; true. CC Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269. ST Source(s): ATCC=CCL-121; CCRID; CLS=300216; Cosmic-CLP=907064; DSMZ=ACC-315; ECACC=85111505; JCRB=IFO50354; JCRB=JCRB9113; KCLB=10121; CelloPub=CLPUB00698; PubMed=11416159; PubMed=17254797; PubMed=25877200; RCB=RCB1956; Technion Genomics Center ST Amelogenin: X,Y ST CSF1PO: 11 (PubMed=17254797) ST CSF1PO: 12 (ATCC=CCL-121; CCRID; CLS=300216; Cosmic-CLP=907064; DSMZ=ACC-315; ECACC=85111505; JCRB=IFO50354; JCRB=JCRB9113; KCLB=10121; PubMed=25877200; RCB=RCB1956; Technion Genomics Center) ST D10S1248: 13,15 ST D12S391: 20,22 ST D13S317: 12,14 ST D16S539: 9,12 ST D18S51: 12,18 ST D19S433: 13.2,15 (CCRID; Technion Genomics Center) ST D19S433: 14,15 (DSMZ=ACC-315) ST D1S1656: 16,17.3 ST D21S11: 28,30 ST D22S1045: 11,16 ST D2S1338: 25,26 ST D2S441: 10,14 ST D3S1358: 16 ST D5S818: 11,13 ST D7S820: 9,10 ST D8S1179: 13,14 ST DYS391: 10 ST FGA: 22,25 ST Penta D: 9,12 ST Penta E: 5,15 ST TH01: 6 ST TPOX: 8 ST vWA: 14,19 DI NCIt; C3043; Fibrosarcoma DI ORDO; Orphanet_2030; Fibrosarcoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 35Y CA Cancer cell line DT Created: 04-04-12; Last updated: 27-11-25; Version: 51 CH CVCL_1D50 ! 2C4 [Human fibrosarcoma] CH CVCL_0115 ! 2fTGH CH CVCL_8870 ! FLYA13 CH CVCL_8871 ! FLYRD18 CH CVCL_RW47 ! HL116 CH CVCL_3715 ! HP CH CVCL_XG90 ! HT-1080 JH-1/FIX CH CVCL_DF43 ! HT-1080 NucLight Green CH CVCL_DF44 ! HT-1080 NucLight Red CH CVCL_V355 ! HT-1080 Tet-Off CH CVCL_UZ99 ! HT-1080-Luc2 CH CVCL_VI98 ! HT-1080/Arabidopsis hybrid chr15 CH CVCL_JG56 ! HT-1080/CMV-Luc CH CVCL_C3V7 ! HT-1080/hCLDN-1 CH CVCL_C3V8 ! HT-1080/hCLDN-2 CH CVCL_C3V9 ! HT-1080/hCLDN-3 CH CVCL_C3VA ! HT-1080/hCLDN-4 CH CVCL_C3VB ! HT-1080/hCLDN-5 CH CVCL_C3VC ! HT-1080/hCLDN-6 CH CVCL_C3VD ! HT-1080/hCLDN-7 CH CVCL_C3VE ! HT-1080/hCLDN-9 CH CVCL_AR54 ! HT-STAR CH CVCL_E8JI ! HT1080 cyno OX40 CH CVCL_C0RF ! HT1080 EGFP CH CVCL_C0RG ! HT1080 EWSR1-FLI1-EGFP CH CVCL_AX37 ! HT1080 FUS-DDIT3-EGFP CH CVCL_XZ54 ! HT1080 human CD137 CH CVCL_XZ55 ! HT1080 human CD27 CH CVCL_E8JF ! HT1080 human CD30 CH CVCL_XZ56 ! HT1080 human CD40 CH CVCL_E8JG ! HT1080 human FAP CH CVCL_UE32 ! HT1080 human GITR CH CVCL_UE31 ! HT1080 human OX40 CH CVCL_E8JH ! HT1080 mouse CD40 CH CVCL_RA09 ! HT1080-eGFP-Puro CH CVCL_RA10 ! HT1080-Fluc-Neo/eGFP-Puro CH CVCL_RA11 ! HT1080-Fluc-Neo/iRFP-Puro CH CVCL_RA12 ! HT1080-Fluc-Puro CH CVCL_E8F2 ! HT1080-HMGB1-Lucia CH CVCL_RA13 ! HT1080-hNIS-Neo/eGFP-Puro CH CVCL_RA14 ! HT1080-hNIS-Neo/Fluc-Puro CH CVCL_RA15 ! HT1080-hNIS-Neo/iRFP-Puro CH CVCL_RA16 ! HT1080-hNIS-Puro CH CVCL_RA17 ! HT1080-iRFP-Puro CH CVCL_L898 ! HT1080-luc2 CH CVCL_ZJ81 ! HT1080-MFAP4 W235F-MH CH CVCL_ZJ80 ! HT1080-MFAP4 wt-MH CH CVCL_5I99 ! HT1080-Red-FLuc CH CVCL_C9F8 ! HT1080/Cas9 AAVS1 CH CVCL_6C48 ! HT1080/DR4 CH CVCL_WM79 ! HTC75 CH CVCL_D683 ! HTD114 CH CVCL_3318 ! HX CH CVCL_D6BS ! HyCyte HT-1080 KO-hSMARCA4 CH CVCL_V634 ! JH-2/TPA CH CVCL_8437 ! PEAZ-1 CH CVCL_D9WD ! Ubigene HT-1080 AIFM2 KO CH CVCL_D9WE ! Ubigene HT-1080 RIPK1 KO // RX CelloPub=CLPUB00698; RA van Bokhoven, Adrie RT "Models for prostate cancer. Molecular characterization and critical RT appraisal of human prostate carcinoma cell lines."; RL Thesis PhD (2004); Katholieke Universiteit Nijmegen; Nijmegen; Netherlands. // RX PubMed=6652615; DOI=10.1016/0165-4608(83)90092-4; RA Chen, Tchaw-Ren RA Hay, Robert J. RA Macy, Marvin L. RT "Intercellular karyotypic similarity in near-diploid cell lines of RT human tumor origins."; RL Cancer Genet. Cytogenet. 10:351-362(1983). // RX PubMed=11668190; DOI=10.1177/002215540104901105; RA Quentmeier, Hilmar RA Osborn, Mary RA Reinhardt, Julia RA Zaborski, Margarete RA Drexler, Hans Gunther RT "Immunocytochemical analysis of cell lines derived from solid RT tumors."; RL J. Histochem. Cytochem. 49:1369-1378(2001). // RX PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001; RA Azari, Shahram RA Ahmadi, Nahid RA Jeddi-Tehrani, Mahmood RA Shokri, Fazel RT "Profiling and authentication of human cell lines using short tandem RT repeat (STR) loci: report from the National Cell Bank of Iran."; RL Biologicals 35:195-202(2007). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=3558490; DOI=10.1002/jcp.1041300303; RA Gupta, Radhey Shyam RA Dudani, Anil Kumar RT "Species-specific differences in the toxicity of rhodamine 123 towards RT cultured mammalian cells."; RL J. Cell. Physiol. 130:321-327(1987). // RX PubMed=3335022; RA Alley, Michael Curtis RA Scudiero, Dominic A. RA Monks, Anne RA Hursey, Miriam L. RA Czerwinski, Maciej J. RA Fine, Donald L. RA Abbott, Betty Jane RA Mayo, Joseph G. RA Shoemaker, Robert H. RA Boyd, Michael R. RT "Feasibility of drug screening with panels of human tumor cell lines RT using a microculture tetrazolium assay."; RL Cancer Res. 48:589-601(1988). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=12068308; DOI=10.1038/nature00766; RA Davies, Helen R. RA Bignell, Graham Robert RA Cox, Charles RA Stephens, Philip J. RA Edkins, Sarah RA Clegg, Sheila RA Teague, Jon W. RA Woffendin, Hayley RA Garnett, Mathew J. RA Bottomley, William RA Davis, Neil RA Dicks, Ed RA Ewing, Rebecca RA Floyd, Yvonne RA Gray, Kristian RA Hall, Sarah RA Hawes, Rachel RA Hughes, Jaime RA Kosmidou, Vivian RA Menzies, Andrew RA Mould, Catherine RA Parker, Adrian RA Stevens, Claire RA Watt, Stephen RA Hooper, Steven RA Wilson, Rebecca RA Jayatilake, Hiran RA Gusterson, Barry Austin RA Cooper, Colin S. RA Shipley, Janet M. RA Hargrave, Darren RA Pritchard-Jones, Kathryn RA Maitland, Norman J. RA Chenevix-Trench, Georgia RA Riggins, Gregory J. RA Bigner, Darell Doty RA Palmieri, Giuseppe RA Cossu, Antonio RA Flanagan, Adrienne Margaret RA Nicholson, Andrew RA Ho, Judy W.C. RA Leung, Suet Yi RA Yuen, Siu Tsan RA Weber, Barbara L. RA Seigler, Hilliard Foster RA Darrow, Timothy L. RA Paterson, Hugh F. RA Marais, Richard RA Marshall, Christopher John RA Wooster, Richard RA Stratton, Michael Rudolf RA Futreal, P. Andrew RT "Mutations of the BRAF gene in human cancer."; RL Nature 417:949-954(2002). // RX PubMed=6538202; DOI=10.1083/jcb.98.3.1133; PMCID=PMC2113122; RA Azzarone, Bruno RA Suarez, Horacio Guillermo RA Mingari, Maria Cristina RA Moretta, Lorenzo RA Fauci, Anthony Stephen RT "4F2 monoclonal antibody recognizes a surface antigen on spread human RT fibroblasts of embryonic but not of adult origin."; RL J. Cell Biol. 98:1133-1137(1984). // RX PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476; RA Teicher, Beverly A. RA Polley, Eric C. RA Kunkel, Mark W. RA Evans, David RA Silvers, Thomas E. RA Delosh, Rene M. RA Laudeman, Julie RA Ogle, Chad RA Reinhart, Russell RA Selby, Michael RA Connelly, John RA Harris, Erik RA Monks, Anne RA Morris, Joel RT "Sarcoma cell line screen of oncology drugs and investigational agents RT identifies patterns associated with gene and microRNA expression."; RL Mol. Cancer Ther. 14:2452-2462(2015). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=375235; DOI=10.1073/pnas.76.3.1288; PMCID=PMC383236; RA Sherwin, Stephen A. RA Sliski, Ann H. RA Todaro, George J. RT "Human melanoma cells have both nerve growth factor and nerve growth RT factor-specific receptors on their cell surfaces."; RL Proc. Natl. Acad. Sci. U.S.A. 76:1288-1292(1979). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=24726063; DOI=10.1186/1756-9966-33-33; PMCID=PMC4022359; RA Koelsche, Christian RA Renner, Marcus RA Hartmann, Wolfgang RA Brandt, Regine RA Lehner, Burkhard RA Waldburger, Nina RA Alldinger, Ingo RA Schmitt, Thomas RA Egerer, Gerlinde RA Penzel, Roland RA Wardelmann, Eva RA Schirmacher, Peter RA von Deimling, Andreas RA Mechtersheimer, Gunhild RT "TERT promoter hotspot mutations are recurrent in myxoid liposarcomas RT but rare in other soft tissue sarcoma entities."; RL J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014). // RX PubMed=3413074; DOI=10.1073/pnas.85.16.6042; PMCID=PMC281901; RA Pereira-Smith, Olivia M. RA Smith, James R. RT "Genetic analysis of indefinite division in human cells: RT identification of four complementation groups."; RL Proc. Natl. Acad. Sci. U.S.A. 85:6042-6046(1988). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459; RA Masters, John R.W. RA Thomson, Jim A. RA Daly-Burns, Bernadette RA Reid, Yvonne A. RA Dirks, Wilhelm Gerhard RA Packer, Phil RA Toji, Lorraine Hellenga RA Ohno, Tadao RA Tanabe, Hideyuki RA Arlett, Colin Francis RA Kelland, Lloyd R. RA Harrison, Maureen RA Virmani, Arvind K. RA Ward, Timothy H. RA Ayres, Karen L. RA Debenham, Paul G. RT "Short tandem repeat profiling provides an international reference RT standard for human cell lines."; RL Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=6304521; DOI=10.1038/303396a0; RA Hall, Alan RA Marshall, Christopher John RA Spurr, Nigel K. RA Weiss, Robin Anthony RT "Identification of transforming gene in two human sarcoma cell lines RT as a new member of the ras gene family located on chromosome 1."; RL Nature 303:396-400(1983). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=3986962; DOI=10.1093/carcin/6.4.549; RA Watatani, Masahiro RA Ikenaga, Mituo RA Hatanaka, Toshihiro RA Kinuta, Masakatsu RA Takai, Shin-ichiro RA Mori, Takesada RA Kondo, Sohei RT "Analysis of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced DNA RT damage in tumor cell strains from Japanese patients and demonstration RT of MNNG hypersensitivity of Mer xenografts in athymic nude mice."; RL Carcinogenesis 6:549-553(1985). // RX PubMed=4132053; DOI=10.1002/1097-0142(197404)33:4<1027::AID-CNCR2820330419>3.0.CO;2-Z; RA Rasheed, Suraiya RA Nelson-Rees, Walter Anthony RA Toth, Eva M. RA Arnstein, Paul RA Gardner, Murray B. RT "Characterization of a newly derived human sarcoma cell line (HT-1080)."; RL Cancer 33:1027-1033(1974). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=22282976; DOI=10.1093/carcin/1.1.21; RA Day, Rufus S. 3rd RA Ziolkowski, Chuck H.J. RA Scudiero, Dominic A. RA Meyer, Sharon A. RA Mattern, Michael R. RT "Human tumor cell strains defective in the repair of alkylation RT damage."; RL Carcinogenesis 1:21-32(1980). // RX PubMed=26368816; DOI=10.1371/journal.pone.0133813; PMCID=PMC4569544; RA Li, Lu-Yuan RA Paz, Ana C. RA Wilky, Breelyn A. RA Johnson, Britt RA Galoian, Karina RA Rosenberg, Andrew RA Hu, Guo-Zhi RA Tinoco, Gabriel RA Bodamer, Olaf A. RA Trent, Jonathan C. 2nd RT "Treatment with a small molecule mutant IDH1 inhibitor suppresses RT tumorigenic activity and decreases production of the oncometabolite RT 2-hydroxyglutarate in human chondrosarcoma cells."; RL PLoS ONE 10:e0133813.1-e0133813.19(2015). //