ID   HCT 15
AC   CVCL_0292
SY   HCT-15; HCT.15; HCT15
DR   BTO; BTO_0002201
DR   CLO; CLO_0003666
DR   EFO; EFO_0002188
DR   MCCL; MCC:0000182
DR   CLDB; cl1576
DR   CLDB; cl4985
DR   ABM; T8966
DR   AddexBio; C0009010/381
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CCL-225
DR   BCRC; 60539
DR   BioGRID_ORCS_Cell_line; 868
DR   BioSample; SAMN01821556
DR   BioSample; SAMN01821630
DR   BioSample; SAMN03471553
DR   BioSample; SAMN10987770
DR   cancercelllines; CVCL_0292
DR   CCRID; 1101HUM-PUMC000247
DR   CCRID; 3101HUMTCHu133
DR   CCRID; 4201HUM-CCTCC00250
DR   CCTCC; GDC0250
DR   Cell_Model_Passport; SIDM00789
DR   ChEMBL-Cells; CHEMBL3307945
DR   ChEMBL-Targets; CHEMBL612263
DR   CLS; 300229
DR   ColonAtlas; HCT15
DR   Cosmic; 711261
DR   Cosmic; 873700
DR   Cosmic; 875902
DR   Cosmic; 887222
DR   Cosmic; 897458
DR   Cosmic; 905007
DR   Cosmic; 905937
DR   Cosmic; 913889
DR   Cosmic; 934567
DR   Cosmic; 947354
DR   Cosmic; 995403
DR   Cosmic; 1044258
DR   Cosmic; 1057756
DR   Cosmic; 1066206
DR   Cosmic; 1092601
DR   Cosmic; 1122324
DR   Cosmic; 1132569
DR   Cosmic; 1175841
DR   Cosmic; 1184092
DR   Cosmic; 1187307
DR   Cosmic; 1218878
DR   Cosmic; 1305354
DR   Cosmic; 1310950
DR   Cosmic; 1312338
DR   Cosmic; 1436020
DR   Cosmic; 1466814
DR   Cosmic; 1479592
DR   Cosmic; 1526922
DR   Cosmic; 1609492
DR   Cosmic; 1676747
DR   Cosmic; 1708403
DR   Cosmic; 1995438
DR   Cosmic; 1998443
DR   Cosmic; 2036655
DR   Cosmic; 2156942
DR   Cosmic; 2301979
DR   Cosmic; 2664053
DR   Cosmic; 2727470
DR   Cosmic; 2760066
DR   Cosmic; 2800585
DR   Cosmic; 2811051
DR   Cosmic-CLP; 905937
DR   DepMap; ACH-000997
DR   DSMZ; ACC-357
DR   DSMZCellDive; ACC-357
DR   ECACC; 91030712
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   EGA; EGAS00001002554
DR   GDSC; 905937
DR   GEO; GSM2129
DR   GEO; GSM50189
DR   GEO; GSM50253
DR   GEO; GSM206502
DR   GEO; GSM274763
DR   GEO; GSM274764
DR   GEO; GSM481406
DR   GEO; GSM513816
DR   GEO; GSM514293
DR   GEO; GSM741257
DR   GEO; GSM743444
DR   GEO; GSM750792
DR   GEO; GSM784011
DR   GEO; GSM799332
DR   GEO; GSM799395
DR   GEO; GSM844554
DR   GEO; GSM846356
DR   GEO; GSM887063
DR   GEO; GSM888133
DR   GEO; GSM1153402
DR   GEO; GSM1178151
DR   GEO; GSM1178152
DR   GEO; GSM1178153
DR   GEO; GSM1181251
DR   GEO; GSM1181363
DR   GEO; GSM1346875
DR   GEO; GSM1374519
DR   GEO; GSM1374520
DR   GEO; GSM1374521
DR   GEO; GSM1374522
DR   GEO; GSM1448178
DR   GEO; GSM1669869
DR   GEO; GSM2124665
DR   GEO; GSM2550002
DR   IARC_TP53; 21114
DR   ICLC; HTL00001
DR   IGRhCellID; HCT15
DR   KCB; KCB 2011097YJ
DR   KCLB; 10225
DR   LiGeA; CCLE_761
DR   LINCS_LDP; LCL-1178
DR   Lonza; 492
DR   MetaboLights; MTBLS227
DR   NCI-DTP; HCT-15
DR   PharmacoDB; HCT15_518_2019
DR   PRIDE; PXD005235
DR   PRIDE; PXD005942
DR   PRIDE; PXD005946
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0292
DR   PubChem_Cell_line; CVCL_0292
DR   RCB; RCB1958
DR   SKY/M-FISH/CGH; 2786
DR   TKG; TKG 0504
DR   TOKU-E; 1423
DR   Wikidata; Q54882006
RX   PubMed=427742;
RX   PubMed=2041050;
RX   PubMed=7139607;
RX   PubMed=7247963;
RX   PubMed=7621404;
RX   PubMed=7972006;
RX   PubMed=8197130;
RX   PubMed=8464898;
RX   PubMed=9000147;
RX   PubMed=9000572;
RX   PubMed=9331090;
RX   PubMed=9809040;
RX   PubMed=10700174;
RX   PubMed=10737795;
RX   PubMed=11314036;
RX   PubMed=11414198;
RX   PubMed=11416159;
RX   PubMed=11526487;
RX   PubMed=11668190;
RX   PubMed=12584437;
RX   PubMed=15748285;
RX   PubMed=15900046;
RX   PubMed=16854228;
RX   PubMed=17088437;
RX   PubMed=18167186;
RX   PubMed=19372543;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20570890;
RX   PubMed=20606684;
RX   PubMed=22068913;
RX   PubMed=22336246;
RX   PubMed=22347499;
RX   PubMed=22384151;
RX   PubMed=22460905;
RX   PubMed=22628656;
RX   PubMed=23856246;
RX   PubMed=23933261;
RX   PubMed=24042735;
RX   PubMed=24279929;
RX   PubMed=24670534;
RX   PubMed=24755471;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25926053;
RX   PubMed=25944804;
RX   PubMed=26169745;
RX   PubMed=26537799;
RX   PubMed=26589293;
RX   PubMed=27377824;
RX   PubMed=27397505;
RX   PubMed=27807467;
RX   PubMed=28179481;
RX   PubMed=28192450;
RX   PubMed=28196595;
RX   PubMed=28683746;
RX   PubMed=28854368;
RX   PubMed=29444439;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=31978347;
RX   PubMed=35839778;
RX   PubMed=38861359;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm
WW   Info; NIBSC; -; https://nibsc.org/science_and_research/advanced_therapies/genomic_reference_materials/1st_cancer_genomes/hct_15.aspx
WW   Info; Pawefish; -; https://www.cellosaurus.org/pawefish/ColonCellLineDescriptions/HCT15.html
WW   Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=20
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/colon-cancer-xenograft/hct-15-xenograft-model/
WW   Provider; BRICS; BRICS0127; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3930
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: JFCR39 cancer cell line panel.
CC   Part of: KuDOS 95 cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: NCI RAS program mutant KRAS cell line panel.
CC   Part of: NCI-60 cancer cell line panel.
CC   Part of: PI3K genetic alteration cell panel (ATCC TCP-1028).
CC   Part of: RAS genetic alteration cell panel (ATCC TCP-1031).
CC   Population: Caucasian.
CC   Doubling time: 19 hours (PubMed=427742); ~20 hours (PubMed=7139607); 29.57 hours (PubMed=25944804); 15 hours (CLS=300229); ~20-25 hours (DSMZ=ACC-357); 20.6 hours (NCI-DTP=HCT-15).
CC   HLA typing: A*02,24; B*08,35:01:01; C*04,07; DPB1*01:01:01,04:01; DQB1*02,05:03:01; DRB1*03,14 (PubMed=15748285).
CC   HLA typing: A*02:01,24:02; B*08:01,35:01; C*04:01,07:06; DQB1*05:03,05:03 (PubMed=26589293).
CC   Microsatellite instability: Instable (MSI-high) (PubMed=11526487; PubMed=24042735; PubMed=24755471; PubMed=25926053; PubMed=28683746; PubMed=31068700; Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Arg727Met (c.2180G>T); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Lys993Asn (c.2979G>T); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Ile1417Leufs*2 (c.4248delC); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Arg2166Ter (c.6496C>T); ClinVar=VCV000438883; Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:914; B2M; Simple; c.68-1G>T; Zygosity=Heterozygous; Note=Splice acceptor mutation (PubMed=8197130; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:914; B2M; Simple; p.Tyr30Ter (c.90C>A); Zygosity=Heterozygous (PubMed=8197130; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Cys1200Terfs (c.3599_3600delGT) (3827delGT); Zygosity=Heterozygous (PubMed=17088437; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Asn1784Hisfs*7 (c.5350_5351delAA); ClinVar=VCV000037959; Zygosity=Heterozygous (PubMed=17088437; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:16627; CHEK2; Simple; p.Arg145Trp (c.433C>T); ClinVar=VCV000005592; Zygosity=Heterozygous (PubMed=18167186; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (PubMed=17088437; PubMed=20570890; PubMed=24755471; PubMed=28683746; ATCC=CCL-225; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (PubMed=17088437; PubMed=20570890; PubMed=24755471; PubMed=28683746; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Asp549Asn (c.1645G>A); ClinVar=VCV000375900; Zygosity=Heterozygous (PubMed=17088437; PubMed=20570890; PubMed=24755471; PubMed=28683746; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser241Phe (c.722C>T); ClinVar=VCV000012359; Zygosity=Heterozygous (PubMed=9000147; PubMed=15900046; PubMed=17088437; PubMed=28683746; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.1101-2A>C; ClinVar=VCV000635383; Zygosity=Heterozygous; Note=Splice acceptor mutation (PubMed=9000147; PubMed=15900046; PubMed=17088437; PubMed=28683746; Cosmic-CLP=905937; DepMap=ACH-000997).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Glycomics; N-glycan profiling.
CC   Omics: Metabolomics.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Phenotyping; Fluorescent probe library screening.
CC   Omics: Proteomics.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; PTM; Phosphorylation; Quantitative.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; lncRNA profiling; RT-qPCR platform.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=2.68%; Native American=0%; East Asian, North=5.84%; East Asian, South=0%; South Asian=0%; European, North=49.17%; European, South=42.32% (PubMed=30894373).
CC   Misspelling: HTC-15; Note=Occasionally.
CC   Misspelling: HTC15; Note=Occasionally.
CC   Discontinued: RCB; RCB1958; true.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
CC   Cell type: Epithelial cell of colon; CL=CL_0011108.
ST   Source(s): AddexBio=C0009010/381; ATCC=CCL-225; CCRID; CLS=300229; Cosmic-CLP=905937; DSMZ=ACC-357; ECACC=91030712; KCLB=10225; PubMed=11416159; PubMed=19372543; PubMed=25877200; PubMed=25926053; Technion Genomics Center; TKG=TKG 0504
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D10S1248: 13,15
ST   D12S391: 19,22
ST   D13S317: 8,11
ST   D16S539: 12,13
ST   D18S51: 11,17
ST   D19S433: 14,16
ST   D1S1656: 17.3,19.3
ST   D21S11: 29,32.2
ST   D22S1045: 17
ST   D2S1338: 17,25
ST   D2S441: 13,15
ST   D3S1358: 17
ST   D5S818: 13
ST   D7S820: 10,12
ST   D8S1179: 15
ST   DYS391: 11
ST   FGA: 15,22 (DSMZ=ACC-357)
ST   FGA: 22 (ATCC=CCL-225; CCRID; CLS=300229; PubMed=11416159; PubMed=19372543; PubMed=25877200; Technion Genomics Center)
ST   Penta D: 9,14
ST   Penta E: 7,14
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 18,19
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3449 ! __Parent_cell_line_of_DLD-1/HCT 8/HCT 15/HRT-18
SX   Male
AG   67Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 51
//
RX   PubMed=427742;
RA   Dexter, Daniel L.
RA   Barbosa, James A.
RA   Calabresi, Paul
RT   "N,N-dimethylformamide-induced alteration of cell culture
RT   characteristics and loss of tumorigenicity in cultured human colon
RT   carcinoma cells.";
RL   Cancer Res. 39:1020-1025(1979).
//
RX   PubMed=2041050; DOI=10.1093/jnci/83.11.757;
RA   Monks, Anne
RA   Scudiero, Dominic A.
RA   Skehan, Philip
RA   Shoemaker, Robert H.
RA   Paull, Kenneth D.
RA   Vistica, David T.
RA   Hose, Curtis D.
RA   Langley, John
RA   Cronise, Paul
RA   Vaigro-Wolff, Anne
RA   Gray-Goodrich, Marcia
RA   Campbell, Hugh
RA   Mayo, Joseph G.
RA   Boyd, Michael R.
RT   "Feasibility of a high-flux anticancer drug screen using a diverse
RT   panel of cultured human tumor cell lines.";
RL   J. Natl. Cancer Inst. 83:757-766(1991).
//
RX   PubMed=7139607;
RA   Dexter, Daniel L.
RA   Spremulli, Ellen N.
RA   Matook, George M.
RA   Diamond, Israel
RA   Calabresi, Paul
RT   "Inhibition of the growth of human colon cancer xenografts by polar
RT   solvents.";
RL   Cancer Res. 42:5018-5022(1982).
//
RX   PubMed=7247963; DOI=10.1016/0006-2952(81)90167-2;
RA   Crabtree, Gerald W.
RA   Dexter, Daniel L.
RA   Stoeckler, Johanna D.
RA   Savarese, Todd M.
RA   Ghoda, Lucy Y.
RA   Rogler-Brown, Timothy L.
RA   Calabresi, Paul
RA   Parks, Robert E. Jr.
RT   "Activities of purine-metabolizing enzymes in human colon carcinoma
RT   cell lines and xenograft tumors.";
RL   Biochem. Pharmacol. 30:793-798(1981).
//
RX   PubMed=7621404; DOI=10.1016/0165-4608(94)00225-z;
RA   Chen, Tchaw-Ren
RA   Dorotinsky, Catherine S.
RA   McGuire, Linda J.
RA   Macy, Marvin L.
RA   Hay, Robert J.
RT   "DLD-1 and HCT-15 cell lines derived separately from colorectal
RT   carcinomas have totally different chromosome changes but the same
RT   genetic origin.";
RL   Cancer Genet. Cytogenet. 81:103-108(1995).
//
RX   PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163;
RA   Okamoto, Aikou
RA   Demetrick, Douglas J.
RA   Spillare, Elisa A.
RA   Hagiwara, Koichi
RA   Hussain, S. Perwez
RA   Bennett, William P.
RA   Forrester, Kathleen
RA   Gerwin, Brenda Isen
RA   Serrano, Manuel
RA   Beach, David H.
RA   Harris, Curtis Craig
RT   "Mutations and altered expression of p16INK4 in human cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994).
//
RX   PubMed=8197130; DOI=10.1073/pnas.91.11.4751; PMCID=PMC43866;
RA   Bicknell, David C.
RA   Rowan, Andrew J.
RA   Bodmer, Walter Fred
RT   "Beta 2-microglobulin gene mutations: a study of established
RT   colorectal cell lines and fresh tumors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:4751-4755(1994).
//
RX   PubMed=8464898; DOI=10.1073/pnas.90.7.2842; PMCID=PMC46192;
RA   Browning, Michael J.
RA   Krausa, Peter
RA   Rowan, Andrew J.
RA   Bicknell, David C.
RA   Bodmer, Julia Gwynaeth
RA   Bodmer, Walter Fred
RT   "Tissue typing the HLA-A locus from genomic DNA by sequence-specific
RT   PCR: comparison of HLA genotype and surface expression on colorectal
RT   tumor cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:2842-2845(1993).
//
RX   PubMed=9000147;
RA   Cottu, Paul-Henri
RA   Muzeau, Francoise
RA   Estreicher, Anne
RA   Flejou, Jean-Francois
RA   Iggo, Richard D.
RA   Thomas, Gilles
RA   Hamelin, Richard
RT   "Inverse correlation between RER+ status and p53 mutation in
RT   colorectal cancer cell lines.";
RL   Oncogene 13:2727-2730(1996).
//
RX   PubMed=9000572;
RA   Hoang, Jean-Marc
RA   Cottu, Paul-Henri
RA   Thuille, Benedicte
RA   Salmon, Remi J.
RA   Thomas, Gilles
RA   Hamelin, Richard
RT   "BAT-26, an indicator of the replication error phenotype in colorectal
RT   cancers and cell lines.";
RL   Cancer Res. 57:300-303(1997).
//
RX   PubMed=9331090;
RA   O'Connor, Patrick M.
RA   Jackman, Joany
RA   Bae, Insoo
RA   Myers, Timothy Gene
RA   Fan, Sai-Jun
RA   Mutoh, Masato
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Sausville, Edward A.
RA   Weinstein, John N.
RA   Friend, Stephen H.
RA   Fornace, Albert J. Jr.
RA   Kohn, Kurt W.
RT   "Characterization of the p53 tumor suppressor pathway in cell lines of
RT   the National Cancer Institute anticancer drug screen and correlations
RT   with the growth-inhibitory potency of 123 anticancer agents.";
RL   Cancer Res. 57:4285-4300(1997).
//
RX   PubMed=9809040; DOI=10.1016/S0165-4608(98)00081-8;
RA   Vermeulen, Stefan Joris
RA   Chen, Tchaw-Ren
RA   Speleman, Frank
RA   Nollet, Friedel
RA   Van Roy, Frans M.
RA   Mareel, Marc M.
RT   "Did the four human cancer cell lines DLD-1, HCT-15, HCT-8, and HRT-18
RT   originate from one and the same patient?";
RL   Cancer Genet. Cytogenet. 107:76-79(1998).
//
RX   PubMed=10700174; DOI=10.1038/73432;
RA   Ross, Douglas T.
RA   Scherf, Uwe
RA   Eisen, Michael Bruce
RA   Perou, Charles M.
RA   Rees, Christian
RA   Spellman, Paul T.
RA   Iyer, Vishwanath R.
RA   Jeffrey, Stefanie S.
RA   van de Rijn, Matt
RA   Waltham, Mark C.
RA   Pergamenschikov, Alexander
RA   Lee, Jeffrey C.F.
RA   Lashkari, Deval
RA   Shalon, Dari
RA   Myers, Timothy Gene
RA   Weinstein, John N.
RA   Botstein, David
RA   Brown, Patrick O'Reilly
RT   "Systematic variation in gene expression patterns in human cancer cell
RT   lines.";
RL   Nat. Genet. 24:227-235(2000).
//
RX   PubMed=10737795; DOI=10.1073/pnas.97.7.3352; PMCID=PMC16243;
RA   Rowan, Andrew J.
RA   Lamlum, Hanan
RA   Ilyas, Mohammad
RA   Wheeler, James M.D.
RA   Straub, Jannes
RA   Papadopoulou, Angeliki
RA   Bicknell, David C.
RA   Bodmer, Walter Fred
RA   Tomlinson, Ian Philip Mark
RT   "APC mutations in sporadic colorectal tumors: a mutational 'hotspot'
RT   and interdependence of the 'two hits'.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:3352-3357(2000).
//
RX   PubMed=11314036; DOI=10.1038/sj.onc.1204211;
RA   Forgacs, Eva
RA   Wren, Jonathan D.
RA   Kamibayashi, Craig
RA   Kondo, Masashi
RA   Xu, Xie L.
RA   Markowitz, Sanford David
RA   Tomlinson, Gail E.
RA   Muller, Carolyn Y.
RA   Gazdar, Adi F.
RA   Garner, Harold Ray
RA   Minna, John D.
RT   "Searching for microsatellite mutations in coding regions in lung,
RT   breast, ovarian and colorectal cancers.";
RL   Oncogene 20:1005-1009(2001).
//
RX   PubMed=11414198; DOI=10.1007/s004320000207;
RA   Lahm, Harald
RA   Andre, Sabine
RA   Hoeflich, Andreas
RA   Fischer, Jurgen R.
RA   Sordat, Bernard
RA   Kaltner, Herbert
RA   Wolf, Eckhard
RA   Gabius, Hans-Joachim
RT   "Comprehensive galectin fingerprinting in a panel of 61 human tumor
RT   cell lines by RT-PCR and its implications for diagnostic and
RT   therapeutic procedures.";
RL   J. Cancer Res. Clin. Oncol. 127:375-386(2001).
//
RX   PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459;
RA   Masters, John R.W.
RA   Thomson, Jim A.
RA   Daly-Burns, Bernadette
RA   Reid, Yvonne A.
RA   Dirks, Wilhelm Gerhard
RA   Packer, Phil
RA   Toji, Lorraine H.
RA   Ohno, Tadao
RA   Tanabe, Hideyuki
RA   Arlett, Colin Francis
RA   Kelland, Lloyd R.
RA   Harrison, Maureen
RA   Virmani, Arvind K.
RA   Ward, Timothy H.
RA   Ayres, Karen L.
RA   Debenham, Paul G.
RT   "Short tandem repeat profiling provides an international reference
RT   standard for human cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
//
RX   PubMed=11526487; DOI=10.1038/sj.onc.1204611;
RA   Gayet, Jacqueline
RA   Zhou, Xiao-Ping
RA   Duval, Alex
RA   Rolland, Sandra
RA   Hoang, Jean-Marc
RA   Cottu, Paul-Henri
RA   Hamelin, Richard
RT   "Extensive characterization of genetic alterations in a series of
RT   human colorectal cancer cell lines.";
RL   Oncogene 20:5025-5032(2001).
//
RX   PubMed=11668190; DOI=10.1177/002215540104901105;
RA   Quentmeier, Hilmar
RA   Osborn, Mary
RA   Reinhardt, Julia
RA   Zaborski, Margarete
RA   Drexler, Hans Gunther
RT   "Immunocytochemical analysis of cell lines derived from solid
RT   tumors.";
RL   J. Histochem. Cytochem. 49:1369-1378(2001).
//
RX   PubMed=12584437; DOI=10.1159/000068544;
RA   Melcher, Ralph
RA   Koehler, Sigrid
RA   Steinlein, Claus
RA   Schmid, Michael
RA   Mueller, Clemens R.
RA   Luehrs, Hardi
RA   Menzel, Thomas
RA   Scheppach, Wolfgang
RA   Moerk, Hubert
RA   Scheurlen, Michael
RA   Koehrle, Josef
RA   Al-Taie, Oliver
RT   "Spectral karyotype analysis of colon cancer cell lines of the tumor
RT   suppressor and mutator pathway.";
RL   Cytogenet. Genome Res. 98:22-28(2002).
//
RX   PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742;
RA   Adams, Sharon
RA   Robbins, Fu-Meei
RA   Chen, Deborah
RA   Wagage, Devika
RA   Holbeck, Susan L.
RA   Morse, Herbert Carpenter 3rd
RA   Stroncek, David
RA   Marincola, Francesco M.
RT   "HLA class I and II genotype of the NCI-60 cell lines.";
RL   J. Transl. Med. 3:11.1-11.8(2005).
//
RX   PubMed=15900046; DOI=10.1093/jnci/dji133;
RA   Mashima, Tetsuo
RA   Oh-hara, Tomoko
RA   Sato, Shigeo
RA   Mochizuki, Mikiko
RA   Sugimoto, Yoshikazu
RA   Yamazaki, Kanami
RA   Hamada, Jun-ichi
RA   Tada, Mitsuhiro
RA   Moriuchi, Tetsuya
RA   Ishikawa, Yuichi
RA   Kato, Yo
RA   Tomoda, Hiroshi
RA   Yamori, Takao
RA   Tsuruo, Takashi
RT   "p53-defective tumors with a functional apoptosome-mediated pathway: a
RT   new therapeutic target.";
RL   J. Natl. Cancer Inst. 97:765-777(2005).
//
RX   PubMed=16854228; DOI=10.1186/1476-4598-5-29; PMCID=PMC1550420;
RA   Bandres Elizalde, Eva Maria
RA   Cubedo, Elena
RA   Agirre, Xabier
RA   Malumbres, Raquel
RA   Zarate, Ruth
RA   Ramirez, Natalia
RA   Abajo, Ana
RA   Navarro, Alfons
RA   Moreno, Isabel
RA   Monzo, Mariano
RA   Garcia-Foncillas, Jesus
RT   "Identification by real-time PCR of 13 mature microRNAs differentially
RT   expressed in colorectal cancer and non-tumoral tissues.";
RL   Mol. Cancer 5:29.1-29.10(2006).
//
RX   PubMed=17088437; DOI=10.1158/1535-7163.MCT-06-0433; PMCID=PMC2705832;
RA   Ikediobi, Ogechi N.
RA   Davies, Helen R.
RA   Bignell, Graham Robert
RA   Edkins, Sarah
RA   Stevens, Claire
RA   O'Meara, Sarah
RA   Santarius, Thomas
RA   Avis, Tim
RA   Barthorpe, Syd
RA   Brackenbury, Lisa
RA   Buck, Gemma
RA   Butler, Adam P.
RA   Clements, Jody
RA   Cole, Jennifer
RA   Dicks, Ed
RA   Forbes, Simon
RA   Gray, Kristian
RA   Halliday, Kelly
RA   Harrison, Rachel
RA   Hills, Katy
RA   Hinton, Jonathan
RA   Hunter, Chris
RA   Jenkinson, Andy
RA   Jones, David
RA   Kosmidou, Vivian
RA   Lugg, Richard
RA   Menzies, Andrew
RA   Mironenko, Tatiana
RA   Parker, Adrian
RA   Perry, Janet
RA   Raine, Keiran Martin
RA   Richardson, David
RA   Shepherd, Rebecca
RA   Small, Alex
RA   Smith, Raffaella
RA   Solomon, Helen
RA   Stephens, Philip J.
RA   Teague, Jon W.
RA   Tofts, Calli
RA   Varian, Jennifer
RA   Webb, Tony
RA   West, Sofie
RA   Widaa, Sara
RA   Yates, Andy
RA   Reinhold, William C.
RA   Weinstein, John N.
RA   Stratton, Michael Rudolf
RA   Futreal, P. Andrew
RA   Wooster, Richard
RT   "Mutation analysis of 24 known cancer genes in the NCI-60 cell line
RT   set.";
RL   Mol. Cancer Ther. 5:2606-2612(2006).
//
RX   PubMed=18167186; DOI=10.5555/cmj.0366-6999.120.23.p2119.01;
RA   Liu, Wei-Dong
RA   Zhong, Bai-Yun
RA   Zhang, Yang-De
RA   Choi, Gyu-Seog
RT   "Mutation analysis of the checkpoint kinase 2 gene in colorectal
RT   cancer cell lines.";
RL   Chin. Med. J. 120:2119-2123(2007).
//
RX   PubMed=19372543; DOI=10.1158/1535-7163.MCT-08-0921; PMCID=PMC4020356;
RA   Lorenzi, Philip L.
RA   Reinhold, William C.
RA   Varma, Sudhir
RA   Hutchinson, Amy A.
RA   Pommier, Yves
RA   Chanock, Stephen Jacob
RA   Weinstein, John N.
RT   "DNA fingerprinting of the NCI-60 cell line panel.";
RL   Mol. Cancer Ther. 8:713-724(2009).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514;
RA   Janakiraman, Manickam
RA   Vakiani, Efsevia
RA   Zeng, Zhao-Shi
RA   Pratilas, Christine A.
RA   Taylor, Barry Stephen
RA   Chitale, Dhananjay
RA   Halilovic, Ensar
RA   Wilson, Manda
RA   Huberman, Kety
RA   Ricarte Filho, Julio Cezar Marques
RA   Persaud, Yogindra
RA   Levine, Douglas A.
RA   Fagin, James Alexander
RA   Jhanwar, Suresh C.
RA   Mariadason, John M.
RA   Lash, Alex
RA   Ladanyi, Marc
RA   Saltz, Leonard B.
RA   Heguy, Adriana
RA   Paty, Philip B.
RA   Solit, David B.
RT   "Genomic and biological characterization of exon 4 KRAS mutations in
RT   human cancer.";
RL   Cancer Res. 70:5901-5911(2010).
//
RX   PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028;
RA   Bracht, Karin
RA   Nicholls, Angela M.
RA   Liu, Ying
RA   Bodmer, Walter Fred
RT   "5-fluorouracil response in a large panel of colorectal cancer cell
RT   lines is associated with mismatch repair deficiency.";
RL   Br. J. Cancer 103:340-346(2010).
//
RX   PubMed=22068913; DOI=10.1073/pnas.1111840108; PMCID=PMC3219108;
RA   Gillet, Jean-Pierre
RA   Calcagno, Anna Maria
RA   Varma, Sudhir
RA   Marino, Miguel
RA   Green, Lisa J.
RA   Vora, Meena I.
RA   Patel, Chirayu
RA   Orina, Josiah N.
RA   Eliseeva, Tatiana A.
RA   Singal, Vineet
RA   Padmanabhan, Raji
RA   Davidson, Ben
RA   Ganapathi, Ram
RA   Sood, Anil K.
RA   Rueda, Bo R.
RA   Ambudkar, Suresh V.
RA   Gottesman, Michael Marc
RT   "Redefining the relevance of established cancer cell lines to the
RT   study of mechanisms of clinical anti-cancer drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:18708-18713(2011).
//
RX   PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017;
RA   Kong, De-Xin
RA   Yamori, Takao
RT   "JFCR39, a panel of 39 human cancer cell lines, and its application in
RT   the discovery and development of anticancer drugs.";
RL   Bioorg. Med. Chem. 20:1947-1951(2012).
//
RX   PubMed=22347499; DOI=10.1371/journal.pone.0031628; PMCID=PMC3276511;
RA   Ruan, Xiao-Yang
RA   Kocher, Jean-Pierre A.
RA   Pommier, Yves
RA   Liu, Hong-Fang
RA   Reinhold, William C.
RT   "Mass homozygotes accumulation in the NCI-60 cancer cell lines as
RT   compared to HapMap trios, and relation to fragile site location.";
RL   PLoS ONE 7:e31628.1-e31628.9(2012).
//
RX   PubMed=22384151; DOI=10.1371/journal.pone.0032096; PMCID=PMC3285665;
RA   Lee, Jun-Seok
RA   Kim, Yun Kyung
RA   Kim, Han Jo
RA   Hajar, Siti
RA   Tan, Yee Ling
RA   Kang, Nam-Young
RA   Ng, Shin Hui
RA   Yoon, Chang No
RA   Chang, Young-Tae
RT   "Identification of cancer cell-line origins using fluorescence
RT   image-based phenomic screening.";
RL   PLoS ONE 7:e32096.1-e32096.8(2012).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura E.
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=22628656; DOI=10.1126/science.1218595; PMCID=PMC3526189;
RA   Jain, Mohit
RA   Nilsson, Roland
RA   Sharma, Sonia
RA   Madhusudhan, Nikhil
RA   Kitami, Toshimori
RA   Souza, Amanda L.
RA   Kafri, Ran
RA   Kirschner, Marc Wallace
RA   Clish, Clary B.
RA   Mootha, Vamsi Krishna
RT   "Metabolite profiling identifies a key role for glycine in rapid
RT   cancer cell proliferation.";
RL   Science 336:1040-1044(2012).
//
RX   PubMed=23856246; DOI=10.1158/0008-5472.CAN-12-3342; PMCID=PMC4893961;
RA   Abaan, Ogan Demir
RA   Polley, Eric C.
RA   Davis, Sean R.
RA   Zhu, Yue-Lin J.
RA   Bilke, Sven
RA   Walker, Robert L.
RA   Pineda, Marbin A.
RA   Gindin, Yevgeniy
RA   Jiang, Yuan
RA   Reinhold, William C.
RA   Holbeck, Susan L.
RA   Simon, Richard M.
RA   Doroshow, James H.
RA   Pommier, Yves
RA   Meltzer, Paul S.
RT   "The exomes of the NCI-60 panel: a genomic resource for cancer biology
RT   and systems pharmacology.";
RL   Cancer Res. 73:4372-4382(2013).
//
RX   PubMed=23933261; DOI=10.1016/j.celrep.2013.07.018;
RA   Moghaddas Gholami, Amin
RA   Hahne, Hannes
RA   Wu, Zhi-Xiang
RA   Auer, Florian Johann
RA   Meng, Chen
RA   Wilhelm, Mathias
RA   Kuster, Bernhard
RT   "Global proteome analysis of the NCI-60 cell line panel.";
RL   Cell Rep. 4:609-620(2013).
//
RX   PubMed=24042735; DOI=10.1038/oncsis.2013.35; PMCID=PMC3816225;
RA   Ahmed, Deeqa
RA   Eide, Peter W.
RA   Eilertsen, Ina A.
RA   Danielsen, Stine A.
RA   Eknaes, Mette
RA   Hektoen, Merete
RA   Lind, Guro Elisabeth
RA   Lothe, Ragnhild Adelheid
RT   "Epigenetic and genetic features of 24 colon cancer cell lines.";
RL   Oncogenesis 2:e71.1-e71.8(2013).
//
RX   PubMed=24279929; DOI=10.1186/2049-3002-1-20; PMCID=PMC4178206;
RA   Dolfi, Sonia C.
RA   Chan, Leo Li-Ying
RA   Qiu, Jean
RA   Tedeschi, Philip M.
RA   Bertino, Joseph Rocco
RA   Hirshfield, Kim Marie
RA   Oltvai, Zoltan Nagy
RA   Vazquez, Alexei
RT   "The metabolic demands of cancer cells are coupled to their size and
RT   protein synthesis rates.";
RL   Cancer Metab. 1:20.1-20.13(2013).
//
RX   PubMed=24670534; DOI=10.1371/journal.pone.0092047; PMCID=PMC3966786;
RA   Varma, Sudhir
RA   Pommier, Yves
RA   Sunshine, Margot
RA   Weinstein, John N.
RA   Reinhold, William C.
RT   "High resolution copy number variation data in the NCI-60 cancer cell
RT   lines from whole genome microarrays accessible through CellMiner.";
RL   PLoS ONE 9:e92047.1-e92047.15(2014).
//
RX   PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013;
RA   Mouradov, Dmitri
RA   Sloggett, Clare
RA   Jorissen, Robert N.
RA   Love, Christopher G.
RA   Li, Shan
RA   Burgess, Antony Wilks
RA   Arango, Diego
RA   Strausberg, Robert L.
RA   Buchanan, Daniel
RA   Wormald, Samuel
RA   O'Connor, Liam
RA   Wilding, Jennifer L.
RA   Bicknell, David C.
RA   Tomlinson, Ian Philip Mark
RA   Bodmer, Walter Fred
RA   Mariadason, John M.
RA   Sieber, Oliver M.
RT   "Colorectal cancer cell lines are representative models of the main
RT   molecular subtypes of primary cancer.";
RL   Cancer Res. 74:3238-3247(2014).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico, Enzo
RA   Russo, Mariangela
RA   Picco, Gabriele
RA   Cancelliere, Carlotta
RA   Valtorta, Emanuele
RA   Corti, Giorgio
RA   Buscarino, Michela
RA   Isella, Claudio
RA   Lamba, Simona
RA   Martinoglio, Barbara
RA   Veronese, Silvio
RA   Siena, Salvatore
RA   Sartore-Bianchi, Andrea
RA   Beccuti, Marco
RA   Mottolese, Marcella
RA   Linnebacher, Michael
RA   Cordero, Francesca
RA   Di Nicolantonio, Federica
RA   Bardelli, Alberto
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//
RX   PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457;
RA   Bazzocco, Sarah
RA   Dopeso, Higinio
RA   Carton-Garcia, Fernando
RA   Macaya, Irati
RA   Andretta, Elena
RA   Chionh, Fiona
RA   Rodrigues, Paulo
RA   Garrido, Miriam
RA   Alazzouzi, Hafid
RA   Nieto, Rocio
RA   Sanchez, Alex
RA   Schwartz, Simo Jr.
RA   Bilic, Josipa
RA   Mariadason, John M.
RA   Arango, Diego
RT   "Highly expressed genes in rapidly proliferating tumor cells as new
RT   targets for colorectal cancer treatment.";
RL   Clin. Cancer Res. 21:3695-3704(2015).
//
RX   PubMed=26169745; DOI=10.1186/s12967-015-0576-z; PMCID=PMC4499939;
RA   Halama, Anna
RA   Guerrouahen, Bella S.
RA   Pasquier, Jennifer
RA   Diboun, Ilhem
RA   Karoly, Edward D.
RA   Suhre, Karsten
RA   Rafii, Arash
RT   "Metabolic signatures differentiate ovarian from colon cancer cell
RT   lines.";
RL   J. Transl. Med. 13:223.1-223.12(2015).
//
RX   PubMed=26537799; DOI=10.1074/mcp.M115.051235; PMCID=PMC4762531;
RA   Holst, Stephanie
RA   Deuss, Anna J.M.
RA   van Pelt, Gabi W.
RA   van Vliet, Sandra Johanna
RA   Garcia-Vallejo, Juan J.
RA   Koeleman, Carolien A.M.
RA   Deelder, Andre M.
RA   Mesker, Wilma E.
RA   Tollenaar, Rob A.E.M.
RA   Rombouts, Yoann
RA   Wuhrer, Manfred
RT   "N-glycosylation profiling of colorectal cancer cell lines reveals
RT   association of fucosylation with differentiation and caudal type
RT   homebox 1 (CDX1)/villin mRNA expression.";
RL   Mol. Cell. Proteomics 15:124-140(2016).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=27377824; DOI=10.1038/sdata.2016.52; PMCID=PMC4932877;
RA   Mestdagh, Pieter
RA   Lefever, Steve
RA   Volders, Pieter-Jan
RA   Derveaux, Stefaan
RA   Hellemans, Jan
RA   Vandesompele, Jo
RT   "Long non-coding RNA expression profiling in the NCI60 cancer cell
RT   line panel using high-throughput RT-qPCR.";
RL   Sci. Data 3:160052.1-160052.6(2016).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=27807467; DOI=10.1186/s13100-016-0078-4; PMCID=PMC5087121;
RA   Zampella, John G.
RA   Rodic, Nemanja
RA   Yang, Wan Rou
RA   Huang, Cheng Ran Lisa
RA   Welch, Jane
RA   Gnanakkan, Veena P.
RA   Cornish, Toby Charles
RA   Boeke, Jef D.
RA   Burns, Kathleen H.
RT   "A map of mobile DNA insertions in the NCI-60 human cancer cell
RT   panel.";
RL   Mob. DNA 7:20.1-20.11(2016).
//
RX   PubMed=28179481; DOI=10.1158/1535-7163.MCT-16-0578;
RA   Tanaka, Noritaka
RA   Mashima, Tetsuo
RA   Mizutani, Anna
RA   Sato, Ayana
RA   Aoyama, Aki
RA   Gong, Bo
RA   Yoshida, Haruka
RA   Muramatsu, Yukiko
RA   Nakata, Kento
RA   Matsuura, Masaaki
RA   Katayama, Ryohei
RA   Nagayama, Satoshi
RA   Fujita, Naoya
RA   Sugimoto, Yoshikazu
RA   Seimiya, Hiroyuki
RT   "APC mutations as a potential biomarker for sensitivity to tankyrase
RT   inhibitors in colorectal cancer.";
RL   Mol. Cancer Ther. 16:752-762(2017).
//
RX   PubMed=28192450; DOI=10.1371/journal.pone.0171435; PMCID=PMC5305277;
RA   Fasterius, Erik
RA   Raso, Cinzia
RA   Kennedy, Susan A.
RA   Rauch, Nora
RA   Lundin, Par
RA   Kolch, Walter
RA   Uhlen, Mathias
RA   Al-Khalili Szigyarto, Cristina
RT   "A novel RNA sequencing data analysis method for cell line
RT   authentication.";
RL   PLoS ONE 12:e0171435.1-e0171435.19(2017).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, A. Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=28683746; DOI=10.1186/s12943-017-0691-y; PMCID=PMC5498998;
RA   Berg, Kaja Christine Graue
RA   Eide, Peter W.
RA   Eilertsen, Ina A.
RA   Johannessen, Bjarne
RA   Bruun, Jarle
RA   Danielsen, Stine A.
RA   Bjornslett, Merete
RA   Meza-Zepeda, Leonardo Andres
RA   Eknaes, Mette
RA   Lind, Guro Elisabeth
RA   Myklebost, Ola
RA   Skotheim, Rolf Inge
RA   Sveen, Anita
RA   Lothe, Ragnhild Adelheid
RT   "Multi-omics of 34 colorectal cancer cell lines -- a resource for
RT   biomedical studies.";
RL   Mol. Cancer 16:116.1-116.16(2017).
//
RX   PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477;
RA   Roumeliotis, Theodoros I.
RA   Williams, Steven P.
RA   Goncalves, Emanuel
RA   Alsinet, Clara
RA   Del Castillo Velasco-Herrera, Martin
RA   Aben, Nanne
RA   Ghavidel, Fatemeh Zamanzad
RA   Michaut, Magali
RA   Schubert, Michael
RA   Price, Stacey
RA   Wright, James C.
RA   Yu, Lu
RA   Yang, Mi
RA   Dienstmann, Rodrigo
RA   Guinney, Justin H.
RA   Beltrao, Pedro
RA   Brazma, Alvis
RA   Pardo, Mercedes
RA   Stegle, Oliver
RA   Adams, David J.
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Choudhary, Jyoti S.
RT   "Genomic determinants of protein abundance variation in colorectal
RT   cancer cells.";
RL   Cell Rep. 20:2201-2214(2017).
//
RX   PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826;
RA   Yuan, Tina L.
RA   Amzallag, Arnaud
RA   Bagni, Rachel
RA   Yi, Ming
RA   Afghani, Shervin
RA   Burgan, William
RA   Fer, Nicole
RA   Strathern, Leslie A.
RA   Powell, Katie
RA   Smith, Brian
RA   Waters, Andrew Michael
RA   Drubin, David Alan
RA   Thomson, Ty
RA   Liao, Rosy
RA   Greninger, Patricia
RA   Stein, Giovanna T.
RA   Murchie, Ellen
RA   Cortez, Eliane
RA   Egan, Regina K.
RA   Procter, Lauren
RA   Bess, Matthew
RA   Cheng, Kwong Tai
RA   Lee, Chih-Shia
RA   Lee, Liam Changwoo
RA   Fellmann, Christof
RA   Stephens, Robert
RA   Luo, Ji
RA   Lowe, Scott William
RA   Benes, Cyril Henri
RA   McCormick, Frank
RT   "Differential effector engagement by oncogenic KRAS.";
RL   Cell Rep. 22:1889-1902(2018).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=30971826; DOI=10.1038/s41586-019-1103-9;
RA   Behan, Fiona M.
RA   Iorio, Francesco
RA   Picco, Gabriele
RA   Goncalves, Emanuel
RA   Beaver, Charlotte M.
RA   Migliardi, Giorgia
RA   Santos, Rita
RA   Rao, Yanhua
RA   Sassi, Francesco
RA   Pinnelli, Marika
RA   Ansari, Rizwan
RA   Harper, Sarah
RA   Jackson, David Adam
RA   McRae, Rebecca
RA   Pooley, Rachel
RA   Wilkinson, Piers
RA   van der Meer, Dieudonne J.
RA   Dow, David
RA   Buser-Doepner, Carolyn A.
RA   Bertotti, Andrea
RA   Trusolino, Livio
RA   Stronach, Euan Alexander
RA   Saez-Rodriguez, Julio
RA   Yusa, Kosuke
RA   Garnett, Mathew J.
RT   "Prioritization of cancer therapeutic targets using CRISPR-Cas9
RT   screens.";
RL   Nature 568:511-516(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254;
RA   Nusinow, David Paul
RA   Szpyt, John
RA   Ghandi, Mahmoud
RA   Rose, Christopher M.
RA   McDonald, E. Robert 3rd
RA   Kalocsay, Marian
RA   Jane-Valbuena, Judit
RA   Gelfand, Ellen T.
RA   Schweppe, Devin K.
RA   Jedrychowski, Mark P.
RA   Golji, Javad
RA   Porter, Dale A.
RA   Rejtar, Tomas
RA   Wang, Y. Karen
RA   Kryukov, Gregory V.
RA   Stegmeier, Frank
RA   Erickson, Brian K.
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RA   Gygi, Steven P.
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//
RX   PubMed=38861359; DOI=10.1158/0008-5472.CAN-23-3031; PMCID=PMC11292194;
RA   Kunkel, Mark W.
RA   Coussens, Nathan P.
RA   Morris, Joel
RA   Taylor, Ronald C.
RA   Dexheimer, Thomas S.
RA   Jones, Eric M.
RA   Doroshow, James H.
RA   Teicher, Beverly A.
RT   "HTS384 NCI60: the next phase of the NCI60 screen.";
RL   Cancer Res. 84:2403-2416(2024).
//