ID COLO 320HSR AC CVCL_0220 SY COLO-320HSR; COLO #320HSR COLO320HSR; COLO 320 HSR; COLO-320-HSR; COLO 320 (HSR); COLO-HSR; Colorado 320 Homogeneously Staining Regions DR CLO; CLO_0002547 DR CLO; CLO_0009960 DR EFO; EFO_0002137 DR MCCL; MCC:0000109 DR CLDB; cl832 DR CLDB; cl833 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-3610 DR ATCC; CCL-220.1 DR BCRC; 60109 DR BioGRID_ORCS_Cell_line; 847 DR BioSample; SAMN03473155 DR cancercelllines; CVCL_0220 DR Cell_Model_Passport; SIDM00842 DR ChEMBL-Cells; CHEMBL3308337 DR ChEMBL-Targets; CHEMBL2366265 DR CLS; 305271 DR ColonAtlas; COLO320HSR DR Cosmic; 720341 DR Cosmic; 808508 DR Cosmic; 910569 DR Cosmic; 1609506 DR Cosmic; 1995369 DR Cosmic-CLP; 910569 DR DepMap; ACH-002219 DR ECACC; 87101501 DR EGA; EGAS00001000978 DR GDSC; 910569 DR GEO; GSM206462 DR GEO; GSM274778 DR GEO; GSM784008 DR GEO; GSM843491 DR GEO; GSM1448182 DR GEO; GSM1669685 DR IARC_TP53; 21232 DR IGRhCellID; COLO320HSR DR KCLB; 10220.1 DR LINCS_LDP; LCL-1189 DR PharmacoDB; COLO320HSR_223_2019 DR PRIDE; PXD005235 DR PRIDE; PXD030304 DR Progenetix; CVCL_0220 DR PubChem_Cell_line; CVCL_0220 DR TOKU-E; 986 DR Wikidata; Q54814091 RX PubMed=498117; RX PubMed=3164477; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=25877200; RX PubMed=25926053; RX PubMed=27397505; RX PubMed=28854368; RX PubMed=29444439; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=35839778; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Population: Caucasian. CC Microsatellite instability: Stable (MSS) (PubMed=25926053; Sanger). CC Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Ser811Ter (c.2432C>G); ClinVar=VCV002203685; Zygosity=Unspecified (from parent cell line). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Unspecified (from parent cell line). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; PTM; Phosphorylation; Quantitative. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0%; Native American=2.14%; East Asian, North=0.47%; East Asian, South=2.14%; South Asian=10.52%; European, North=6.29%; European, South=78.44% (PubMed=30894373). CC Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159. ST Source(s): ATCC=CCL-220.1; Cosmic-CLP=910569; KCLB=10220.1; PubMed=25877200; PubMed=25926053 ST Amelogenin: X ST CSF1PO: 11 ST D13S317: 11 ST D16S539: 11,12 ST D18S51: 15 ST D19S433: 15,16.2 ST D21S11: 31,33.2 ST D2S1338: 18,25 ST D3S1358: 17 ST D5S818: 12 ST D7S820: 9,12 ST D8S1179: 13 ST FGA: 20 ST Penta D: 9,12 ST Penta E: 11,13 ST TH01: 8,9 ST TPOX: 8,9 ST vWA: 15,18 DI NCIt; C4349; Colon adenocarcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) HI CVCL_0219 ! COLO 320DM SX Female AG 55Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 41 // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=498117; RA Quinn, Laurie A. RA Moore, George Eugene RA Morgan, Robert T. RA Woods, Linda K. RT "Cell lines from human colon carcinoma with unusual cell products, RT double minutes, and homogeneously staining regions."; RL Cancer Res. 39:4914-4924(1979). // RX PubMed=3164477; DOI=10.1073/pnas.85.13.4804; PMCID=PMC280524; RA Von Hoff, Daniel D. RA Needham-VanDevanter, Donald R. RA Yucel, Jennifer RA Windle, Bradford E. RA Wahl, Geoffrey Myles RT "Amplified human MYC oncogenes localized to replicating submicroscopic RT circular DNA molecules."; RL Proc. Natl. Acad. Sci. U.S.A. 85:4804-4808(1988). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=25926053; DOI=10.1038/ncomms8002; RA Medico, Enzo RA Russo, Mariangela RA Picco, Gabriele RA Cancelliere, Carlotta RA Valtorta, Emanuele RA Corti, Giorgio RA Buscarino, Michela RA Isella, Claudio RA Lamba, Simona RA Martinoglio, Barbara RA Veronese, Silvio RA Siena, Salvatore RA Sartore-Bianchi, Andrea RA Beccuti, Marco RA Mottolese, Marcella RA Linnebacher, Michael RA Cordero, Francesca RA Di Nicolantonio, Federica RA Bardelli, Alberto RT "The molecular landscape of colorectal cancer cell lines unveils RT clinically actionable kinase targets."; RL Nat. Commun. 6:7002.1-7002.10(2015). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826; RA Yuan, Tina L. RA Amzallag, Arnaud RA Bagni, Rachel RA Yi, Ming RA Afghani, Shervin RA Burgan, William RA Fer, Nicole RA Strathern, Leslie A. RA Powell, Katie RA Smith, Brian RA Waters, Andrew Michael RA Drubin, David Alan RA Thomson, Ty RA Liao, Rosy RA Greninger, Patricia RA Stein, Giovanna T. RA Murchie, Ellen RA Cortez, Eliane RA Egan, Regina K. RA Procter, Lauren RA Bess, Matthew RA Cheng, Kwong Tai RA Lee, Chih-Shia RA Lee, Liam Changwoo RA Fellmann, Christof RA Stephens, Robert RA Luo, Ji RA Lowe, Scott William RA Benes, Cyril Henri RA McCormick, Frank RT "Differential effector engagement by oncogenic KRAS."; RL Cell Rep. 22:1889-1902(2018). // RX PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477; RA Roumeliotis, Theodoros I. RA Williams, Steven P. RA Goncalves, Emanuel RA Alsinet, Clara RA Del Castillo Velasco-Herrera, Martin RA Aben, Nanne RA Ghavidel, Fatemeh Zamanzad RA Michaut, Magali RA Schubert, Michael RA Price, Stacey RA Wright, James C. RA Yu, Lu RA Yang, Mi RA Dienstmann, Rodrigo RA Guinney, Justin H. RA Beltrao, Pedro RA Brazma, Alvis RA Pardo, Mercedes RA Stegle, Oliver RA Adams, David J. RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Choudhary, Jyoti S. RT "Genomic determinants of protein abundance variation in colorectal RT cancer cells."; RL Cell Rep. 20:2201-2214(2017). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). //