ID   Beta-TC-tet
AC   CVCL_0185
SY   BetaTCtet; betaTC-tet
DR   MCCL; MCC:0000076
DR   ATCC; CRL-3237
DR   Wikidata; Q54796105
RX   PubMed=7724601;
RX   PubMed=11900281;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=betaTC-tet
CC   Characteristics: Expression of the SV40 T-antigen is under the control of the tet operator sequence. Shows growth arrest and further differentiation upon addition of 5 ng/ml tetracycline (PubMed=7724601).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
CC   Cell type: Pancreatic beta cell; CL=CL_0000169.
CC   Breed/subspecies: C3HeB/FeJ transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Age unspecified
CA   Conditionally immortalized cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 16
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RX   PubMed=7724601; DOI=10.1073/pnas.92.8.3576; PMCID=PMC42210;
RA   Efrat, Shimon
RA   Fusco-DeMane, David
RA   Lemberg, Hadas
RA   Al Emran, Obaidullah
RA   Wang, Xiao-Rong
RT   "Conditional transformation of a pancreatic beta-cell line derived
RT   from transgenic mice expressing a tetracycline-regulated oncogene.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:3576-3580(1995).
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RX   PubMed=11900281; DOI=10.1080/15604280212526; PMCID=PMC2478570;
RA   Landesman-Milo, Dalit
RA   Efrat, Shimon
RT   "Growth factor-dependent proliferation of the pancreatic beta-cell
RT   line betaTC-tet: an assay for beta-cell mitogenic factors.";
RL   Int. J. Exp. Diabetes Res. 3:69-74(2002).
//