ID   BALB/3T3 clone A31
AC   CVCL_0184
SY   BALB/c 3T3 clone A31; Balb/c3T3; BALB/c 3T3; Balb/c 3T3; BALB/3T3; Balb/3T3-4-Cl31; 3T3 clone A31; BALB/3T3 cl. A31; BALB 3T3 clone A31; BALB/3T3 (clone A31); B/C3T3; 3T3-A31; 3T3(A31); A31; A31N
DR   BTO; BTO_0000218
DR   CLO; CLO_0001346
DR   CLO; CLO_0001859
DR   CLO; CLO_0050542
DR   MCCL; MCC:0000075
DR   CLDB; cl385
DR   CLDB; cl386
DR   CLDB; cl387
DR   CLDB; cl388
DR   CLDB; cl389
DR   CLDB; cl7216
DR   ATCC; CCL-163
DR   ATCC; CRL-6587
DR   ATCC; CRL-6588
DR   BCRC; 60009
DR   BCRJ; 0047
DR   BioSample; SAMN11397624
DR   CCRID; 1101MOU-PUMC000186
DR   CCRID; 1102MOU-NIFDC00085
DR   CCRID; 3101MOUGNM3
DR   CCRID; 4201MOU-CCTCC00224
DR   CCTCC; GDC0224
DR   ChEMBL-Cells; CHEMBL3308086
DR   ChEMBL-Targets; CHEMBL613876
DR   CLS; 305155
DR   ECACC; 86110401
DR   ICLC; AL09001
DR   IZSLER; BS CL 4
DR   JCRB; JCRB9005
DR   KCB; KCB 200713YJ
DR   KCLB; 10163
DR   Lonza; 1351
DR   MeSH; D041702
DR   NCBI_Iran; C162
DR   PubChem_Cell_line; CVCL_0184
DR   RCB; RCB0005
DR   RCB; RCB2647
DR   TKG; TKG 0187
DR   TOKU-E; 615
DR   TOKU-E; 3612
DR   Wikidata; Q28334278
RX   PubMed=50878;
RX   PubMed=182373;
RX   PubMed=4301006;
RX   PubMed=4359949;
RX   PubMed=4792350;
RX   PubMed=4798834;
RX   PubMed=10848989;
RX   PubMed=22576795;
RX   PubMed=25277546;
RX   PubMed=31220119;
WW   Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/atcc-ccl-163-growth-and-morphology
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-255.html
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Doubling time: 30-32 hours (Note=At 33 Celsius) (PubMed=4798834); 24 hours (Note=At 38 Celsius) (PubMed=182373).
CC   Omics: Variations; SNP array analysis.
CC   Misspelling: BABL/3T3; KCB=KCB 200713YJ.
CC   Discontinued: ATCC; CRL-6587; true.
CC   Discontinued: ATCC; CRL-6588; true.
CC   Discontinued: BioSample; SAMN11397624; true.
CC   Discontinued: RCB; RCB2647; true.
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: BALB/c.
ST   Source(s): PubMed=31220119
ST   Mouse STR 1-1: 16
ST   Mouse STR 1-2: 17
ST   Mouse STR 2-1: 16
ST   Mouse STR 3-2: 14
ST   Mouse STR 4-2: 21.3
ST   Mouse STR 5-5: 14
ST   Mouse STR 6-4: 18
ST   Mouse STR 6-7: 12
ST   Mouse STR 7-1: 25.2
ST   Mouse STR 8-1: 13
ST   Mouse STR 11-2: 17
ST   Mouse STR 12-1: 16
ST   Mouse STR 13-1: 16.2
ST   Mouse STR 15-3: 22.3
ST   Mouse STR 17-2: 15,16
ST   Mouse STR 18-3: 18
ST   Mouse STR 19-2: 14
ST   Mouse STR X-1: 25
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   14-17FD
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 34
//
RX   PubMed=50878;
RA   Quarles J.M., Tennant R.W.;
RT   "Effects of nitrosocarbaryl on BALB/3T3 cells.";
RL   Cancer Res. 35:2637-2643(1975).
//
RX   PubMed=182373; DOI=10.1016/0092-8674(76)90028-3;
RA   Slater M.L., Ozer H.L.;
RT   "Temperature-sensitive mutants of Balb/3T3 cells: description of a
RT   mutant affected in cellular and polyoma virus DNA synthesis.";
RL   Cell 7:289-295(1976).
//
RX   PubMed=4301006; DOI=10.1002/jcp.1040720208;
RA   Aaronson S.A., Todaro G.J.;
RT   "Development of 3T3-like lines from Balb-c mouse embryo cultures:
RT   transformation susceptibility to SV40.";
RL   J. Cell. Physiol. 72:141-148(1968).
//
RX   PubMed=4359949; DOI=10.1128/JVI.12.4.711-720.1973; PMCID=PMC356689;
RA   Benveniste R.E., Todaro G.J., Scolnick E.M., Parks W.P.;
RT   "Partial transcription of murine type C viral genomes in BALB c cell
RT   lines.";
RL   J. Virol. 12:711-720(1973).
//
RX   PubMed=4792350; DOI=10.1002/ijc.2910120217;
RA   Kakunaga T.;
RT   "A quantitative system for assay of malignant transformation by
RT   chemical carcinogens using a clone derived from BALB-3T3.";
RL   Int. J. Cancer 12:463-473(1973).
//
RX   PubMed=4798834; DOI=10.1016/0014-4827(73)90283-8;
RA   Wittes R.E., Ozer H.L.;
RT   "Characterization of a temperature-sensitive mutant of BALB/c 3T3
RT   cells.";
RL   Exp. Cell Res. 80:127-136(1973).
//
RX   PubMed=10848989; DOI=10.1046/j.1432-1327.2000.01404.x;
RA   Salvat C., Acquaviva C., Scheffner M., Robbins I., Piechaczyk M.,
RA   Jariel-Encontre I.;
RT   "Molecular characterization of the thermosensitive E1
RT   ubiquitin-activating enzyme cell mutant A31N-ts20. Requirements upon
RT   different levels of E1 for the ubiquitination/degradation of the
RT   various protein substrates in vivo.";
RL   Eur. J. Biochem. 267:3712-3722(2000).
//
RX   PubMed=22576795; DOI=10.3892/or.2012.1763;
RA   Ashinuma H., Takiguchi Y., Kitazono S., Kitazono-Saitoh M.,
RA   Kitamura A., Chiba T., Tada Y., Kurosu K., Sakaida E., Sekine I.,
RA   Tanabe N., Iwama A., Yokosuka O., Tatsumi K.;
RT   "Antiproliferative action of metformin in human lung cancer cell
RT   lines.";
RL   Oncol. Rep. 28:8-14(2012).
//
RX   PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738;
RA   Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W.,
RA   Morse H.C. 3rd, Pardo-Manuel de Villena F.;
RT   "SNP array profiling of mouse cell lines identifies their strains of
RT   origin and reveals cross-contamination and widespread aneuploidy.";
RL   BMC Genomics 15:847.1-847.11(2014).
//
RX   PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308;
RA   Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S.,
RA   Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H.,
RA   Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B.,
RA   Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.;
RT   "Interlaboratory study to validate a STR profiling method for
RT   intraspecies identification of mouse cell lines.";
RL   PLoS ONE 14:e0218412.1-e0218412.24(2019).
//