ID   BC3H1
AC   CVCL_0163
SY   BC3 H1; BC3H-1; BC-3H-1; BC-3-H-I
DR   BTO; BTO:0000115
DR   CLO; CLO_0001894
DR   MCCL; MCC:0000055
DR   CLDB; cl398
DR   CLDB; cl399
DR   CLDB; cl5161
DR   ATCC; CRL-1443
DR   CCRID; 1101MOU-PUMC000096
DR   DSMZ; ACC-171
DR   DSMZCellDive; ACC-171
DR   ECACC; 86093001
DR   IZSLER; BS TCL 145
DR   KCLB; 21443
DR   Wikidata; Q54795220
RX   PubMed=2715180;
RX   PubMed=4363958;
RX   PubMed=10852349;
RX   PubMed=24055552;
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-222.html
CC   Characteristics: Closely resemble cells in an arrested state of skeletal muscle differentiation (PubMed=2715180).
CC   Characteristics: The scorpion toxin Acra3 exerts a very strong cytotoxic effect this cell line (PubMed=24055552).
CC   Doubling time: ~70 hours (DSMZ=ACC-171).
CC   Transformant: ChEBI; CHEBI:23995; N-ethyl-N-nitrosourea (ENU).
CC   Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
CC   Breed/subspecies: C3H.
DI   NCIt; C23988; Mouse neoplasms
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 19
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RX   PubMed=2715180; DOI=10.1083/jcb.108.5.1799;
RA   Taubman M.B., Smith C.W.J., Izumo S., Grant J.W., Endo T., Andreadis A.,
RA   Nadal-Ginard B.;
RT   "The expression of sarcomeric muscle-specific contractile protein
RT   genes in BC3H1 cells: BC3H1 cells resemble skeletal myoblasts that are
RT   defective for commitment to terminal differentiation.";
RL   J. Cell Biol. 108:1799-1806(1989).
//
RX   PubMed=4363958; DOI=10.1083/jcb.61.2.398;
RA   Schubert D., Harris A.J., Devine C.E., Heinemann S.F.;
RT   "Characterization of a unique muscle cell line.";
RL   J. Cell Biol. 61:398-413(1974).
//
RX   PubMed=10852349; DOI=10.1290/1071-2690(2000)036<0241:IOASFB>2.0.CO;2;
RA   Steenstrup T.D., Hannon K.;
RT   "Isolation of a spontaneously fusing BC3H1 muscle cell line: fusion
RT   alters the response to serum stimulation.";
RL   In Vitro Cell. Dev. Biol. Anim. 36:241-248(2000).
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RX   PubMed=24055552; DOI=10.1016/j.toxicon.2013.09.009;
RA   Caliskan F., Ergene E., Sogut I., Hatipoglu I., Basalp A., Sivas H.,
RA   Kanbak G.;
RT   "Biological assays on the effects of Acra3 peptide from Turkish
RT   scorpion Androctonus crassicauda venom on a mouse brain tumor cell
RT   line (BC3H1) and production of specific monoclonal antibodies.";
RL   Toxicon 76:350-361(2013).
//