ID A2780 AC CVCL_0134 SY A-2780; 2780; A2780S; A2780par DR BTO; BTO_0002549 DR CLO; CLO_0001571 DR EFO; EFO_0006362 DR MCCL; MCC:0000027 DR CLDB; cl193 DR CLDB; cl194 DR CLDB; cl4894 DR ABM; T8089 DR AddexBio; C0017002/20 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR BCRJ; 0031 DR BioGRID_ORCS_Cell_line; 329 DR BioSample; SAMN03472806 DR BioSample; SAMN10988216 DR cancercelllines; CVCL_0134 DR CancerTools; 152706 DR Cell_Model_Passport; SIDM00210 DR ChEMBL-Cells; CHEMBL3308421 DR ChEMBL-Targets; CHEMBL614004 DR CLS; 300491 DR Cosmic; 688090 DR Cosmic; 755844 DR Cosmic; 849607 DR Cosmic; 906804 DR Cosmic; 923108 DR Cosmic; 948284 DR Cosmic; 987394 DR Cosmic; 1093558 DR Cosmic; 1102819 DR Cosmic; 1139223 DR Cosmic; 1198265 DR Cosmic; 1305309 DR Cosmic; 1609529 DR Cosmic; 1707564 DR Cosmic; 1708387 DR Cosmic; 1709251 DR Cosmic; 1945872 DR Cosmic; 1995331 DR Cosmic; 2582805 DR Cosmic; 2674698 DR Cosmic-CLP; 906804 DR DepMap; ACH-000657 DR ECACC; 93112519 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 906804 DR GEO; GSM184388 DR GEO; GSM184389 DR GEO; GSM383925 DR GEO; GSM503257 DR GEO; GSM659370 DR GEO; GSM711722 DR GEO; GSM827312 DR GEO; GSM851909 DR GEO; GSM886853 DR GEO; GSM887918 DR GEO; GSM1001419 DR GEO; GSM1001420 DR GEO; GSM1001488 DR GEO; GSM1291126 DR GEO; GSM1291129 DR GEO; GSM1340577 DR GEO; GSM1374380 DR GEO; GSM1374381 DR GEO; GSM1669581 DR GEO; GSM2474971 DR GEO; GSM4845007 DR GEO; GSM4845008 DR GEO; GSM6065211 DR GEO; GSM6065212 DR GEO; GSM6065213 DR Hysigen; TCH-C112 DR IARC_TP53; 21161 DR ICLC; HTL98008 DR LiGeA; CCLE_809 DR LINCS_LDP; LCL-1518 DR Lonza; 207 DR MetaboLights; MTBLS156 DR MetaboLights; MTBLS1014 DR NCI-DCTD; A2780 DR PharmacoDB; A2780_40_2019 DR PRIDE; PXD001176 DR PRIDE; PXD003105 DR PRIDE; PXD003252 DR PRIDE; PXD003668 DR PRIDE; PXD013811 DR PRIDE; PXD030304 DR Progenetix; CVCL_0134 DR PubChem_Cell_line; CVCL_0134 DR Wikidata; Q54606559 DR Ximbio; 152706 RX PubMed=1348364; RX PubMed=1999494; RX PubMed=2429947; RX PubMed=2751261; RX PubMed=3335022; RX PubMed=3539322; RX PubMed=3986765; RX PubMed=6173755; RX PubMed=6372095; RX PubMed=6954533; RX PubMed=7927910; RX PubMed=8012063; RX PubMed=8557231; RX PubMed=9041185; RX PubMed=11103784; RX PubMed=11416159; RX PubMed=12080474; RX PubMed=15677628; RX PubMed=18273836; RX PubMed=19714814; RX PubMed=20164919; RX PubMed=20204287; RX PubMed=20215515; RX PubMed=22328975; RX PubMed=22460905; RX PubMed=22585861; RX PubMed=22705003; RX PubMed=22710073; RX PubMed=23415752; RX PubMed=23839242; RX PubMed=24023729; RX PubMed=25230021; RX PubMed=25485619; RX PubMed=25846456; RX PubMed=25877200; RX PubMed=25984343; RX PubMed=26589293; RX PubMed=26972028; RX PubMed=27141528; RX PubMed=27235858; RX PubMed=27397505; RX PubMed=27561551; RX PubMed=28196595; RX PubMed=28273451; RX PubMed=28546799; RX PubMed=30485824; RX PubMed=30894224; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=33287223; RX PubMed=34071702; RX PubMed=35839778; RX PubMed=36476833; WW Info; ECACC; -; https://www.culturecollections.org.uk/products/cell-cultures/ecacc-cell-line-profiles/a2780/ WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/2/cell-lines-detail-64.html CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: KuDOS 95 cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Part of: OCCP ovarian cancer cell line panel. CC Population: African American. CC Doubling time: 25.3 +- 1 hours (PubMed=3539322); 16 hours (PubMed=25984343); 18.41 hours (JWGray panel). CC HLA typing: A*26:03,26:03; B*37:04,49:01; C*02:02,07:01; DQB1*06:07,06:07; DRB1*01:01,01:01 (PubMed=26589293). CC Microsatellite instability: Instable (MSI-low) (PubMed=15677628; Sanger). CC Sequence variation: Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (PubMed=25846456). CC Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu365Lys (c.1093G>A); ClinVar=VCV000419222; Zygosity=Heterozygous (DepMap=ACH-000657). CC Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Homozygous (PubMed=25230021; DepMap=ACH-000657). CC Sequence variation: Mutation; HGNC; HGNC:17271; RRAS2; Simple; p.Gln72Leu (c.215A>T); ClinVar=VCV000009447; Zygosity=Homozygous (DepMap=ACH-000657). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Genomics; Whole genome sequencing. CC Omics: Glycomics; N-glycan profiling; Lectin array. CC Omics: Metabolomics. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics. CC Omics: Proteomics; 2DE-MS. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; PTM; GPI-anchored proteins. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Transcriptomics; Serial analysis of gene expression (SAGE). CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=93.08%; Native American=0%; East Asian, North=2.76%; East Asian, South=0%; South Asian=0%; European, North=0%; European, South=4.17% (PubMed=30894373). CC Discontinued: ECACC; 93112519; true. CC Derived from site: In situ; Ovary; UBERON=UBERON_0000992. ST Source(s): AddexBio=C0017002/20; Cosmic-CLP=906804; ECACC=93112519; ICLC=HTL98008; PubMed=11416159; PubMed=25230021; PubMed=25877200; PubMed=30485824 ST Amelogenin: X ST CSF1PO: 10,11 ST D13S317: 12,13 ST D16S539: 11,12,13 (ICLC=HTL98008) ST D16S539: 11,13 (AddexBio=C0017002/20; Cosmic-CLP=906804; ECACC=93112519; PubMed=25230021; PubMed=25877200; PubMed=30485824) ST D18S51: 16,18 ST D19S433: 12 ST D21S11: 28 (PubMed=25230021; PubMed=25877200) ST D21S11: 28,29 (PubMed=30485824) ST D2S1338: 21,22 ST D3S1358: 14,16 ST D5S818: 11,12 ST D7S820: 10 ST D8S1179: 15,17 ST FGA: 19,24 ST Penta D: 8,9 ST Penta E: 10,13 ST TH01: 6 ST TPOX: 8,10 ST vWA: 15,16 DI NCIt; C7979; Ovarian endometrioid adenocarcinoma DI ORDO; Orphanet_454723; Endometrioid carcinoma of ovary OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG Age unspecified CA Cancer cell line DT Created: 04-04-12; Last updated: 25-06-26; Version: 51 CH CVCL_C9BP ! 2780AD CH CVCL_C3NF ! A2780 LIN28B KO CH CVCL_C0D6 ! A2780 PTX(4) CH CVCL_E5L2 ! A2780 RRAS2 KO#20 CH CVCL_E5L1 ! A2780 RRAS2 KO#3 CH CVCL_H619 ! A2780-1A9 CH CVCL_ZE22 ! A2780-CBDCA-R CH CVCL_H745 ! A2780-cisR CH CVCL_EG64 ! A2780-DR CH CVCL_4T95 ! A2780-DX1 CH CVCL_TZ68 ! A2780-M CH CVCL_E5I4 ! A2780-NiraR CH CVCL_DI16 ! A2780-SCA CH CVCL_1F93 ! A2780-TC1 CH CVCL_7224 ! A2780/100 CH CVCL_D156 ! A2780/ACR6 CH CVCL_D157 ! A2780/ACRP CH CVCL_B037 ! A2780/AD10 CH CVCL_D537 ! A2780/ADDP CH CVCL_B7S7 ! A2780/C100 CH CVCL_F638 ! A2780/C200 CH CVCL_F639 ! A2780/C30 CH CVCL_B7S6 ! A2780/C300 CH CVCL_B7S8 ! A2780/C50 CH CVCL_B7S5 ! A2780/C80 CH CVCL_D620 ! A2780/CBP CH CVCL_D619 ! A2780/CDDP CH CVCL_Y180 ! A2780/cDDP CH CVCL_A5AB ! A2780/cmv CH CVCL_A5PS ! A2780/CP20 CH CVCL_0135 ! A2780/CP70 CH CVCL_A5PT ! A2780/CP8 CH CVCL_A5AC ! A2780/m175 CH CVCL_A5AD ! A2780/m248 CH CVCL_A5AE ! A2780/m273 CH CVCL_4862 ! A2780/R CH CVCL_4863 ! A2780/S CH CVCL_IJ13 ! A2780/Taxol CH CVCL_4V45 ! A2780/TPT CH CVCL_UJ39 ! A2780AD CH CVCL_1941 ! A2780ADR CH CVCL_1942 ! A2780cis CH CVCL_UJ38 ! A2780ME CH CVCL_C1NE ! A2780veliR CH CVCL_F4WH ! HyCyte A2780 stable cell line for hSNCA overexpression // RX PubMed=6173755; DOI=10.1038/295116a0; RA Eva, Alessandra RA Robbins, Keith Cranston RA Andersen, Philip Roger RA Srinivasan, Alagarsamy RA Tronick, Steven R. RA Reddy, E. Premkumar RA Ellmore, Nelson Wayne RA Galen, Angela T. RA Lautenberger, James Allen RA Papas, Takis S. RA Westin, Eric H. RA Wong-Staal, Flossie RA Gallo, Robert Charles RA Aaronson, Stuart A. RT "Cellular genes analogous to retroviral onc genes are transcribed in RT human tumour cells."; RL Nature 295:116-119(1982). // RX PubMed=7927910; DOI=10.1002/ijc.2910590118; RA Huxham, Ian M. RA Barlow, Andrew L. RA Lewis, Alexander D. RA Plumb, Jane RA Mairs, Robert J. RA Gaze, Mark N. RA Workman, Paul RT "Differential intracellular processing of the anthracycline drug RT ME2303 in doxorubicin-sensitive (A2780) and -resistant (A2780AD) human RT ovarian cancer cells as studied with confocal laser scanning RT microscopy and image analysis."; RL Int. J. Cancer 59:94-102(1994). // RX PubMed=8557231; DOI=10.1006/gyno.1996.0014; RA Skilling, Jeffrey S. RA Squatrito, Robert C. RA Connor, Joseph P. RA Niemann, Theodore RA Buller, Richard E. RT "p53 gene mutation analysis and antisense-mediated growth inhibition RT of human ovarian carcinoma cell lines."; RL Gynecol. Oncol. 60:72-80(1996). // RX PubMed=3986765; RA Louie, Karen Guigere RA Behrens, Brent C. RA Kinsella, Timothy James RA Hamilton, Thomas C. RA Grotzinger, Karen R. RA McKoy, Wilma M. RA Winker, Margaret A. RA Ozols, Robert F. RT "Radiation survival parameters of antineoplastic drug-sensitive and RT -resistant human ovarian cancer cell lines and their modification by RT buthionine sulfoximine."; RL Cancer Res. 45:2110-2115(1985). // RX PubMed=6372095; DOI=10.1126/science.6372095; RA Rogan, Alfred M. RA Hamilton, Thomas C. RA Young, Robert C. RA Klecker, Raymond W. Jr. RA Ozols, Robert F. RT "Reversal of adriamycin resistance by verapamil in human ovarian RT cancer."; RL Science 224:994-996(1984). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=12080474; DOI=10.1038/sj.onc.1205542; RA Manzano, Ramon G. RA Montuenga, Luis M. RA Dayton, Mark A. RA Dent, Paul RA Kinoshita, Ichiro RA Vicent, Silvestre RA Gardner, Ginger J. RA Nguyen, PhuongMai RA Choi, Yung-Hyun RA Trepel, Jane B. RA Auersperg, Nelly RA Birrer, Michael J. RT "CL100 expression is down-regulated in advanced epithelial ovarian RT cancer and its re-expression decreases its malignant potential."; RL Oncogene 21:4435-4447(2002). // RX PubMed=1348364; DOI=10.1073/pnas.89.7.3070; PMCID=PMC48805; RA Godwin, Andrew Kent RA Meister, Alton RA O'Dwyer, Peter J. RA Huang, Chin-Shiou RA Hamilton, Thomas C. RA Anderson, Mary E. RT "High resistance to cisplatin in human ovarian cancer cell lines is RT associated with marked increase of glutathione synthesis."; RL Proc. Natl. Acad. Sci. U.S.A. 89:3070-3074(1992). // RX PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516; RA Hernandez, Lidia RA Kim, Marianne K. RA Lyle, L. Tiffany RA Bunch, Kristen Paige RA House, Carrie D. RA Ning, Franklin RA Noonan, Anne M. RA Annunziata, Christina Messineo RT "Characterization of ovarian cancer cell lines as in vivo models for RT preclinical studies."; RL Gynecol. Oncol. 142:332-340(2016). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=30894224; DOI=10.1186/s40659-019-0220-0; PMCID=PMC6427839; RA Viscarra, Tamara RA Buchegger, Kurt RA Jofre, Ignacio Andres RA Riquelme, Ismael RA Zanella, Louise RA Abanto Marin, Michel RA Parker, Alyssa C. RA Piccolo, Stephen R. RA Roa, Juan Carlos RA Ili, Carmen Gloria RA Brebi, Priscilla RT "Functional and transcriptomic characterization of RT carboplatin-resistant A2780 ovarian cancer cell line."; RL Biol. Res. 52:13.1-13.13(2019). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=3539322; RA Behrens, Brent C. RA Hamilton, Thomas C. RA Masuda, Hidetaka RA Grotzinger, Karen R. RA Whang-Peng, Jacqueline RA Louie, Karen Guigere RA Knutsen, Turid RA McKoy, Wilma M. RA Young, Robert C. RA Ozols, Robert F. RT "Characterization of a cis-diamminedichloroplatinum(II)-resistant RT human ovarian cancer cell line and its use in evaluation of platinum RT analogues."; RL Cancer Res. 47:414-418(1987). // RX PubMed=25230021; DOI=10.1371/journal.pone.0103988; PMCID=PMC4167545; RA Beaufort, Corine M. RA Helmijr, Jean C.A. RA Piskorz, Anna M. RA Hoogstraat, Marlous RA Ruigrok-Ritstier, Kirsten RA Besselink, Nicolle RA Murtaza, Muhammed RA van IJcken, Wilfred F.J. RA Heine, Anouk A.J. RA Smid, Marcel RA Koudijs, Marco J. RA Brenton, James D. RA Berns, Els M.J.J. RA Helleman, Jozien RT "Ovarian cancer cell line panel (OCCP): clinical importance of in RT vitro morphological subtypes."; RL PLoS ONE 9:e103988.1-e103988.16(2014). // RX PubMed=27561551; DOI=10.1038/ncomms12645; PMCID=PMC5007461; RA Coscia, Fabian RA Watters, Karen M. RA Curtis, Marion RA Eckert, Mark A. RA Chiang, Chun-Yi RA Tyanova, Stefka RA Montag, Anthony RA Lastra, Ricardo R. RA Lengyel, Ernst Robert RA Mann, Matthias RT "Integrative proteomic profiling of ovarian cancer cell lines reveals RT precursor cell associated proteins and functional status."; RL Nat. Commun. 7:12645.1-12645.14(2016). // RX PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652; RA Cowley, Glenn S. RA Weir, Barbara A. RA Vazquez, Francisca RA Tamayo, Pablo RA Scott, Justine A. RA Rusin, Scott RA East-Seletsky, Alexandra RA Ali, Levi D. RA Gerath, William F.J. RA Pantel, Sarah E. RA Lizotte, Patrick Hall RA Jiang, Guo-Zhi RA Hsiao, Jessica RA Tsherniak, Aviad RA Dwinell, Elizabeth RA Aoyama, Simon RA Okamoto, Michael RA Harrington, William RA Gelfand, Ellen T. RA Green, Thomas M. RA Tomko, Mark J. RA Gopal, Shuba RA Wong, Terence C. RA Li, Hu-Bo RA Howell, Sara RA Stransky, Nicolas RA Liefeld, Ted RA Jang, Dongkeun RA Bistline, Jonathan RA Meyers, Barbara Hill RA Armstrong, Scott Allen RA Anderson, Kenneth Carl RA Stegmaier, Kimberly RA Reich, Michael RA Pellman, David RA Boehm, Jesse S. RA Mesirov, Jill P. RA Golub, Todd Robert RA Root, David E. RA Hahn, William Chun RT "Parallel genome-scale loss of function screens in 216 cancer cell RT lines for the identification of context-specific genetic RT dependencies."; RL Sci. Data 1:140035.1-140035.12(2014). // RX PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459; RA Masters, John R.W. RA Thomson, Jim A. RA Daly-Burns, Bernadette RA Reid, Yvonne A. RA Dirks, Wilhelm Gerhard RA Packer, Phil RA Toji, Lorraine Hellenga RA Ohno, Tadao RA Tanabe, Hideyuki RA Arlett, Colin Francis RA Kelland, Lloyd R. RA Harrison, Maureen RA Virmani, Arvind K. RA Ward, Timothy H. RA Ayres, Karen L. RA Debenham, Paul G. RT "Short tandem repeat profiling provides an international reference RT standard for human cell lines."; RL Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001). // RX PubMed=3335022; RA Alley, Michael Curtis RA Scudiero, Dominic A. RA Monks, Anne RA Hursey, Miriam L. RA Czerwinski, Maciej J. RA Fine, Donald L. RA Abbott, Betty Jane RA Mayo, Joseph G. RA Shoemaker, Robert H. RA Boyd, Michael R. RT "Feasibility of drug screening with panels of human tumor cell lines RT using a microculture tetrazolium assay."; RL Cancer Res. 48:589-601(1988). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396; RA Marcotte, Richard RA Brown, Kevin R. RA Suarez Saiz, Fernando Jose RA Sayad, Azin RA Karamboulas, Konstantina RA Krzyzanowski, Paul M. RA Sircoulomb, Fabrice RA Medrano, Mauricio RA Fedyshyn, Yaroslav RA Koh, Judice Lie-Yong RA van Dyk, Dewald RA Fedyshyn, Bohdana RA Luhova, Marianna RA Brito, Glauber C. RA Vizeacoumar, Franco J. RA Vizeacoumar, Frederick S. RA Datti, Alessandro RA Kasimer, Dahlia RA Buzina, Alla RA Mero, Patricia RA Misquitta, Christine RA Normand, Josee RA Haider, Maliha RA Ketela, Troy RA Wrana, Jeffrey L. RA Rottapel, Robert RA Neel, Benjamin G. RA Moffat, Jason RT "Essential gene profiles in breast, pancreatic, and ovarian cancer RT cells."; RL Cancer Discov. 2:172-189(2012). // RX PubMed=6954533; DOI=10.1073/pnas.79.7.2194; PMCID=PMC346157; RA Westin, Eric H. RA Gallo, Robert Charles RA Arya, Suresh K. RA Eva, Alessandra RA Souza, Lawrence M. RA Baluda, Marcel Albert RA Aaronson, Stuart A. RA Wong-Staal, Flossie RT "Differential expression of the amv gene in human hematopoietic RT cells."; RL Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=36476833; DOI=10.1038/s41388-022-02563-9; PMCID=PMC9883167; RA Clavain, Laura RA Fernandez-Pisonero, Maria Isabel RA Movilla, Nieves RA Lorenzo-Martin, Luis Francisco RA Nieto, Blanca RA Abad, Antonio RA Garcia-Navas, Rosula RA Llorente-Gonzalez, Clara RA Sanchez-Martin, Manuel RA Vicente-Manzanares, Miguel RA Santos, Eugenio RA Alarcon, Balbino RA Garcia-Aznar, Jose Manuel RA Dosil, Mercedes RA Bustelo, Xose R. RT "Characterization of mutant versions of the R-RAS2/TC21 GTPase found RT in tumors."; RL Oncogene 42:389-405(2023). // RX PubMed=22328975; DOI=10.1158/2159-8290.CD-11-0170; PMCID=PMC3274821; RA Hanrahan, Aphrothiti J. RA Schultz, Nikolaus RA Westfal, Maggie L. RA Sakr, Rita A. RA Giri, Dilip D. RA Scarperi, Stefano RA Janakiraman, Manickam RA Olvera, Narciso RA Stevens, Ellen V. RA She, Qing-Bai RA Aghajanian, Carol RA King, Tari Ann RA de Stanchina, Elisa RA Spriggs, David R. RA Heguy, Adriana RA Taylor, Barry Stephen RA Sander, Chris RA Rosen, Neal RA Levine, Douglas A. RA Solit, David B. RT "Genomic complexity and AKT dependence in serous ovarian cancer."; RL Cancer Discov. 2:56-67(2012). // RX PubMed=25846456; DOI=10.3892/ijo.2015.2951; RA Takenaka, Masataka RA Saito, Motonobu RA Iwakawa, Reika RA Yanaihara, Nozomu RA Saito, Misato RA Kato, Mamoru RA Ichikawa, Hitoshi RA Shibata, Tatsuhiro RA Yokota, Jun RA Okamoto, Aikou RA Kohno, Takashi RT "Profiling of actionable gene alterations in ovarian cancer by RT targeted deep sequencing."; RL Int. J. Oncol. 46:2389-2398(2015). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=8012063; RA Cimoli, Guido RA Valenti, Monica RA Parodi, Silvio RA Mazzoni, Alessandra RA De Sessa, Fabio RA Conte, PierFranco RA Russo, Patrizia RT "Reversal of 'atypical'-multidrug resistance by recombinant human RT tumor necrosis factor in the human ovarian cancer cell line RT A2780-DX3."; RL Oncol. Res. 5:311-323(1993). // RX PubMed=1999494; DOI=10.1172/JCI115080; PMCID=PMC329864; RA Parker, Ricardo J. RA Eastman, Alan RA Bostick-Bruton, Frieda RA Reed, Eddie RT "Acquired cisplatin resistance in human ovarian cancer cells is RT associated with enhanced repair of cisplatin-DNA lesions and reduced RT drug accumulation."; RL J. Clin. Invest. 87:772-777(1991). // RX PubMed=28546799; DOI=10.1186/s12014-017-9155-z; PMCID=PMC5442857; RA Zhao, Ran RA Qin, Wen-Jun RA Qin, Rui-Huan RA Han, Jing RA Li, Can RA Wang, Yi-Sheng RA Xu, Cong-Jian RT "Lectin array and glycogene expression analyses of ovarian cancer cell RT line A2780 and its cisplatin-resistant derivate cell line A2780-cp."; RL Clin. Proteomics 14:20.1-20.10(2017). // RX PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028; RA Medrano, Mauricio RA Communal, Laudine RA Brown, Kevin R. RA Iwanicki, Marcin RA Normand, Josee RA Paterson, Joshua RA Sircoulomb, Fabrice RA Krzyzanowski, Paul M. RA Novak, Marian RA Doodnauth, Sasha A. RA Suarez Saiz, Fernando Jose RA Cullis, Jane RA Al-awar, Rima RA Neel, Benjamin G. RA McPherson, John RA Drapkin, Ronny I. RA Ailles, Laurie RA Mes-Masson, Anne-Marie RA Rottapel, Robert RT "Interrogation of functional cell-surface markers identifies CD151 RT dependency in high-grade serous ovarian cancer."; RL Cell Rep. 18:2343-2358(2017). // RX PubMed=24023729; DOI=10.1371/journal.pone.0072162; PMCID=PMC3762837; RA Anglesio, Michael S. RA Wiegand, Kimberly C. RA Melnyk, Nataliya RA Chow, Christine RA Salamanca, Clara M. RA Prentice, Leah M. RA Senz, Janine RA Yang, Winnie RA Spillman, Monique Ann RA Cochrane, Dawn R. RA Shumansky, Karey RA Shah, Sohrab P. RA Kalloger, Steve E. RA Huntsman, David G. RT "Type-specific cell line models for type-specific ovarian cancer RT research."; RL PLoS ONE 8:e72162.1-e72162.13(2013). // RX PubMed=18273836; DOI=10.1002/gcc.20547; RA Prasad, Mona RA Bernardini, Marcus RA Tsalenko, Anya RA Marrano, Paula RA Paderova, Jana RA Lee, Chung-Hae RA Ben-Dor, Amir RA Barrett, Michael T. RA Squire, Jeremy Andrew RT "High definition cytogenetics and oligonucleotide aCGH analyses of RT cisplatin-resistant ovarian cancer cells."; RL Genes Chromosomes Cancer 47:427-436(2008). // RX PubMed=2429947; DOI=10.20772/cancersci1985.77.9_941; RA Tsuruo, Takashi RA Hamilton, Thomas C. RA Louie, Karen Guigere RA Behrens, Brent C. RA Young, Robert C. RA Ozols, Robert F. RT "Collateral susceptibility of adriamycin-, melphalan- and RT cisplatin-resistant human ovarian tumor cells to bleomycin."; RL Jpn. J. Cancer Res. 77:941-945(1986). // RX PubMed=20204287; DOI=10.3892/or_00000728; PMCID=PMC2909445; RA Langland, Gregory T. RA Yannone, Steven M. RA Langland, Rachel A. RA Nakao, Aki RA Guan, Ying-Hui RA Long, Sydney B.T. RA Vonguyen, Lien RA Chen, David J. RA Gray, Joe W. RA Chen, Fan-Qing RT "Radiosensitivity profiles from a panel of ovarian cancer cell lines RT exhibiting genetic alterations in p53 and disparate DNA-dependent RT protein kinase activities."; RL Oncol. Rep. 23:1021-1026(2010). // RX PubMed=19714814; DOI=10.1021/pr800856b; RA Cicchillitti, Lucia RA Di Michele, Michela RA Urbani, Andrea RA Ferlini, Cristiano RA Donati, Maria Benedetta RA Scambia, Giovanni RA Rotilio, Domenico RT "Comparative proteomic analysis of paclitaxel sensitive A2780 RT epithelial ovarian cancer cell line and its resistant counterpart RT A2780TC1 by 2D-DIGE: the role of ERp57."; RL J. Proteome Res. 8:1902-1912(2009). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=27141528; DOI=10.1016/j.dib.2016.04.001; PMCID=PMC4838930; RA Masuishi, Yusuke RA Kimura, Yayoi RA Arakawa, Noriaki RA Hirano, Hisashi RT "Data for identification of GPI-anchored peptides and omega-sites in RT cancer cell lines."; RL Data Brief 7:1302-1305(2016). // RX PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008; RA Masuishi, Yusuke RA Kimura, Yayoi RA Arakawa, Noriaki RA Hirano, Hisashi RT "Identification of glycosylphosphatidylinositol-anchored proteins and RT omega-sites using TiO2-based affinity purification followed by RT hydrogen fluoride treatment."; RL J. Proteomics 139:77-83(2016). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=9041185; RA Johnson, Steven W. RA Laub, Paul B. RA Beesley, Jacqueline S. RA Ozols, Robert F. RA Hamilton, Thomas C. RT "Increased platinum-DNA damage tolerance is associated with cisplatin RT resistance and cross-resistance to various chemotherapeutic agents in RT unrelated human ovarian cancer cell lines."; RL Cancer Res. 57:850-856(1997). // RX PubMed=2751261; RA Mazzoni, Alessandra RA Trave, Fabio RA Canti, Gianfranco RA Franco, Paola RT "Effect of the tiapamil analog RO11-2933 on cellular sensitivity to RT antitumor drugs in sensitive and multidrug resistant human ovarian RT cancer cells."; RL Anticancer Res. 9:367-371(1989). // RX PubMed=23839242; DOI=10.1038/ncomms3126; PMCID=PMC3715866; RA Domcke, Silvia RA Sinha, Rileen RA Levine, Douglas A. RA Sander, Chris RA Schultz, Nikolaus RT "Evaluating cell lines as tumour models by comparison of genomic RT profiles."; RL Nat. Commun. 4:2126.1-2126.10(2013). // RX PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096; PMCID=PMC6481945; RA Papp, Eniko RA Hallberg, Dorothy RA Konecny, Gottfried E. RA Bruhm, Daniel C. RA Adleff, Vilmos RA Noe, Michael RA Kagiampakis, Ioannis RA Palsgrove, Doreen RA Conklin, Dylan RA Kinose, Yasuto RA White, James R. RA Press, Michael Frederick RA Drapkin, Ronny I. RA Easwaran, Hariharan RA Baylin, Stephen Bruce RA Slamon, Dennis Joseph RA Velculescu, Victor E. RA Scharpf, Robert B. RT "Integrated genomic, epigenomic, and expression analyses of ovarian RT cancer cell lines."; RL Cell Rep. 25:2617-2633(2018). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677; RA Korch, Christopher T. RA Spillman, Monique Ann RA Jackson, Twila A. RA Jacobsen, Britta M. RA Murphy, Susan K. RA Lessey, Bruce Arthur RA Jordan, Virgil Craig RA Bradford, Andrew Peter RT "DNA profiling analysis of endometrial and ovarian cell lines reveals RT misidentification, redundancy and contamination."; RL Gynecol. Oncol. 127:241-248(2012). // RX PubMed=22705003; DOI=10.1016/j.humpath.2012.03.011; RA Rahman, Munmun RA Nakayama, Kentaro RA Rahman, Mohammed Tanjimur RA Nakayama, Naomi RA Ishikawa, Masako RA Katagiri, Atsuko RA Iida, Kouji RA Nakayama, Satoru RA Otsuki, Yoshiro RA Shih, Ie-Ming RA Miyazaki, Kohji RT "Clinicopathologic and biological analysis of PIK3CA mutation in RT ovarian clear cell carcinoma."; RL Hum. Pathol. 43:2197-2206(2012). // RX PubMed=11103784; RA Hough, Colleen D. RA Sherman-Baust, Cheryl A. RA Pizer, Ellen S. RA Montz, Fredrick John RA Im, Dwight D. RA Rosenshein, Neil B. RA Cho, Kathleen R. RA Riggins, Gregory J. RA Morin, Patrice J. RT "Large-scale serial analysis of gene expression reveals genes RT differentially expressed in ovarian cancer."; RL Cancer Res. 60:6281-6287(2000). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=33287223; DOI=10.3390/ijms21239218; PMCID=PMC7730278; RA Szenajch, Jolanta RA Szabelska-Beresewicz, Alicja RA Swiercz, Aleksandra RA Zyprych-Walczak, Joanna RA Siatkowski, Idzi RA Goralski, Michal RA Synowiec, Agnieszka RA Handschuh, Luiza RT "Transcriptome remodeling in gradual development of inverse resistance RT between paclitaxel and cisplatin in ovarian cancer cells."; RL Int. J. Mol. Sci. 21:9218.1-9218.30(2020). // RX PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023; RA Stordal, Britta RA Timms, Kirsten RA Farrelly, Angela RA Gallagher, Danielle RA Busschots, Steven RA Renaud, Mickael RA Thery, Julien RA Williams, Deborah RA Potter, Jennifer RA Tran, Thanh RA Korpanty, Greg RA Cremona, Mattia RA Carey, Mark S. RA Li, Jie RA Li, Yang RA Aslan, Ozlem RA O'Leary, John J. RA Mills, Gordon B. RA Hennessy, Bryan T. RT "BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one RT functionally deleterious BRCA1 mutation."; RL Mol. Oncol. 7:567-579(2013). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=15677628; DOI=10.1093/carcin/bgi032; RA Gorringe, Kylie Louise RA Chin, Suet-Feung RA Pharoah, Paul D.P. RA Staines, Joanne M. RA Oliveira, Carla RA Edwards, Paul A.W. RA Caldas, Carlos RT "Evidence that both genetic instability and selection contribute to RT the accumulation of chromosome alterations in cancer."; RL Carcinogenesis 26:923-930(2005). // RX PubMed=34071702; DOI=10.3390/ijms22115814; PMCID=PMC8198185; RA Golan Berman, Hadar RA Chauhan, Pooja RA Shalev, Shira RA Hassanain, Hiba RA Parnas, Avital RA Adar, Sheera RT "Genomic characterization of cisplatin response uncovers priming of RT cisplatin-induced genes in a resistant cell line."; RL Int. J. Mol. Sci. 22:5814.1-5814.14(2021). //