ID A-172 AC CVCL_0131 SY A172; A 172; A-172 MG; A-172MG DR BTO; BTO_0000016 DR CLO; CLO_0001543 DR CLO; CLO_0001559 DR CLO; CLO_0001560 DR CLO; CLO_0050637 DR EFO; EFO_0002101 DR MCCL; MCC:0000023 DR CLDB; cl142 DR CLDB; cl143 DR CLDB; cl144 DR CLDB; cl146 DR AddexBio; C0005009/5018 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; CRL-1620 DR ATCC; CRL-7899 DR BioGRID_ORCS_Cell_line; 823 DR BioSample; SAMN03471115 DR BioSample; SAMN03471212 DR BioSample; SAMN03471659 DR BioSample; SAMN03471918 DR BioSample; SAMN10988258 DR cancercelllines; CVCL_0131 DR CCRID; 3101HUMTCHu171 DR Cell_Model_Passport; SIDM00799 DR CGH-DB; 138-1 DR ChEMBL-Cells; CHEMBL3308491 DR ChEMBL-Targets; CHEMBL614512 DR CLS; 300108 DR Cosmic; 687563 DR Cosmic; 849883 DR Cosmic; 897446 DR Cosmic; 1014068 DR Cosmic; 1036334 DR Cosmic; 1066233 DR Cosmic; 1171223 DR Cosmic; 1236360 DR Cosmic; 1610751 DR Cosmic; 1746956 DR Cosmic; 1995327 DR Cosmic; 2302321 DR Cosmic; 2367506 DR Cosmic; 2516012 DR Cosmic-CLP; 687563 DR DepMap; ACH-000558 DR ECACC; 88062428 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR ENCODE; ENCBS225AJI DR ENCODE; ENCBS874LTK DR FANTOM5_SSTAR; 10444-106F3 DR GDSC; 687563 DR GEO; GSM101609 DR GEO; GSM101610 DR GEO; GSM326244 DR GEO; GSM886850 DR GEO; GSM887914 DR GEO; GSM1374378 DR GEO; GSM1669577 DR IARC_TP53; 21157 DR ICLC; HTL97013 DR IGRhCellID; A172 DR IZSLER; BS TCL 2 DR JCRB; JCRB0228 DR KCB; KCB 200966YJ DR KCLB; 21620 DR LiGeA; CCLE_757 DR LINCS_LDP; LCL-1348 DR Lonza; 178 DR NCBI_Iran; C211 DR PharmacoDB; A172_36_2019 DR PRIDE; PXD001110 DR PRIDE; PXD030304 DR Progenetix; CVCL_0131 DR PubChem_Cell_line; CVCL_0131 DR RCB; RCB2530 DR TKG; TKG 0183 DR Wikidata; Q54605968 RX DOI=10.1007/0-306-46861-1_11; RX DOI=10.1016/B978-0-12-333530-2.50005-8; RX PubMed=77569; RX PubMed=212188; RX PubMed=450131; RX PubMed=833871; RX PubMed=1255758; RX PubMed=1385192; RX PubMed=3518877; RX PubMed=3675803; RX PubMed=3759084; RX PubMed=4357758; RX PubMed=6173755; RX PubMed=6220172; RX PubMed=6256643; RX PubMed=6260907; RX PubMed=6652614; RX PubMed=6825208; RX PubMed=6954533; RX PubMed=7523863; RX PubMed=9090379; RX PubMed=9220028; RX PubMed=9290701; RX PubMed=9842975; RX PubMed=10402232; RX PubMed=10416987; RX PubMed=10698499; RX PubMed=11351043; RX PubMed=14614447; RX PubMed=14655754; RX PubMed=15900046; RX PubMed=16232199; RX PubMed=16697959; RX PubMed=17254797; RX PubMed=17595512; RX PubMed=19365568; RX PubMed=19435942; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=21406405; RX PubMed=22460905; RX PubMed=22570425; RX PubMed=23637631; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25984343; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=30188626; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=34036375; RX PubMed=35839778; WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/a/cell-lines-detail-280.html CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). CC Part of: PTEN genetic alteration cell panel (ATCC TCP-1030). CC Population: Caucasian. CC Doubling time: 44 hours (PubMed=9842975); 40 hours (PubMed=25984343); 33-48 hours (PubMed=30188626); ~45 hours (Note=Lot 021999), ~30 hours (Note=Lot 06092006), ~42 hours (Note=Lot 06262015), ~26 hours (Note=Lot 12192018) (JCRB=JCRB0228). CC HLA typing: A*01,02; B*07,08 (PubMed=77569). CC HLA typing: A*01:01,03:01; B*07:02,08:01; C*07:01,07:01; DQB1*06:07,06:07; DRB1*11:26,13:09 (PubMed=26589293). CC HLA typing: A*01:01:01,03:01:01; B*07:02:01,08:01:01; C*07:01:01,07:02:01; DPB1*02:01:02G,04:02:01G; DQA1*05:01,05:05; DQB1*02:01,03:01; DRB1*03:01,11:01 (CLS=300108). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (PubMed=9090379). CC Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1539; CBFB; Name(s)=ABL1-CBFB (PubMed=23637631). CC Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; None_reported; -; Zygosity=- (PubMed=19435942). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=14614447; PubMed=15900046). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Phenotyping; shRNA library screening. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0%; Native American=0%; East Asian, North=2.05%; East Asian, South=0%; South Asian=1.21%; European, North=68.98%; European, South=27.77% (PubMed=30894373). CC Discontinued: ATCC; CRL-7899; true. CC Derived from site: In situ; Brain; UBERON=UBERON_0000955. ST Source(s): AddexBio=C0005009/5018; ATCC=CRL-1620; CLS=300108; Cosmic-CLP=687563; ECACC=88062428; IZSLER=BS TCL 2; JCRB=JCRB0228; KCLB=21620; PubMed=17254797; PubMed=22570425; PubMed=25877200; RCB=RCB2530; Technion Genomics Center; TKG=TKG 0183 ST Amelogenin: X,Y ST CSF1PO: 9,11 (PubMed=17254797) ST CSF1PO: 9,12 (AddexBio=C0005009/5018; ATCC=CRL-1620; CLS=300108; Cosmic-CLP=687563; ECACC=88062428; IZSLER=BS TCL 2; JCRB=JCRB0228; KCLB=21620; PubMed=22570425; PubMed=25877200; RCB=RCB2530; Technion Genomics Center; TKG=TKG 0183) ST D10S1248: 15 ST D12S391: 22 ST D13S317: 11 ST D16S539: 11 (PubMed=17254797) ST D16S539: 12 (AddexBio=C0005009/5018; ATCC=CRL-1620; CLS=300108; Cosmic-CLP=687563; ECACC=88062428; IZSLER=BS TCL 2; JCRB=JCRB0228; KCLB=21620; PubMed=22570425; PubMed=25877200; RCB=RCB2530; Technion Genomics Center; TKG=TKG 0183) ST D18S51: 12,13 ST D19S433: 12,15.2 ST D1S1656: 12,14 ST D21S11: 27,32 (PubMed=17254797) ST D21S11: 28,32.2 (ATCC=CRL-1620; CLS=300108; IZSLER=BS TCL 2; PubMed=22570425; PubMed=25877200; Technion Genomics Center) ST D22S1045: 16 ST D2S1338: 20,21 ST D2S441: 10,11 ST D3S1358: 14,18 (ATCC=CRL-1620; CLS=300108; PubMed=22570425; PubMed=25877200; Technion Genomics Center) ST D3S1358: 15,18 (PubMed=17254797) ST D5S818: 11,12 ST D6S1043: 13,18 ST D7S820: 11 ST D8S1179: 13,14 ST DYS391: 11 ST FGA: 20,22 ST Penta D: 9,13 ST Penta E: 5,10 ST TH01: 6,9.3 (AddexBio=C0005009/5018; ATCC=CRL-1620; CLS=300108; Cosmic-CLP=687563; ECACC=88062428; IZSLER=BS TCL 2; KCLB=21620; PubMed=22570425; PubMed=25877200; RCB=RCB2530; Technion Genomics Center; TKG=TKG 0183) ST TH01: 6,10 (JCRB=JCRB0228; PubMed=17254797) ST TPOX: 8,11 ST vWA: 17,20 (RCB=RCB2530) ST vWA: 20 (AddexBio=C0005009/5018; ATCC=CRL-1620; CLS=300108; Cosmic-CLP=687563; ECACC=88062428; IZSLER=BS TCL 2; JCRB=JCRB0228; KCLB=21620; PubMed=17254797; PubMed=22570425; PubMed=25877200; Technion Genomics Center; TKG=TKG 0183) DI NCIt; C3058; Glioblastoma DI ORDO; Orphanet_360; Glioblastoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 53Y CA Cancer cell line DT Created: 04-04-12; Last updated: 27-11-25; Version: 51 CH CVCL_F1JP ! A-172 EMC10 isoform HSS1 CH CVCL_F1JQ ! A-172 neo CH CVCL_D5ZN ! A172/TMZ CH CVCL_5735 ! D-54MG CH CVCL_D6AE ! HyCyte A-172 KO-hTP53 CH CVCL_E3GJ ! HyCyte A-172-Luc // RX PubMed=450131; DOI=10.1038/279797a0; RA Day, Rufus S. 3rd RA Ziolkowski, Chuck H.J. RT "Human brain tumour cell strains with deficient host-cell reactivation RT of N-methyl-N'-nitro-N-nitrosoguanidine-damaged adenovirus 5."; RL Nature 279:797-799(1979). // RX PubMed=6220172; RA Dracopoli, Nicholas C. RA Fogh, Jorgen RT "Polymorphic enzyme analysis of cultured human tumor cell lines."; RL J. Natl. Cancer Inst. 70:469-476(1983). // RX PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x; PMCID=PMC8098486; RA Ishii, Nobuaki RA Maier, Daniel RA Merlo, Adrian RA Tada, Mitsuhiro RA Sawamura, Yutaka RA Diserens, Annie-Claire RA Van Meir, Erwin G. RT "Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor RT suppressor genes in human glioma cell lines."; RL Brain Pathol. 9:469-479(1999). // RX PubMed=9090379; DOI=10.1038/ng0497-356; RA Steck, Peter A. RA Pershouse, Mark A. RA Jasser, Samar A. RA Yung, Wai-Kwan Alfred RA Lin, Huai RA Ligon, Azra Hadi RA Langford, Lauren A. RA Baumgard, Michelle L. RA Hattier, Thomas RA Davis, Thaylon RA Frye, Cheryl RA Hu, Rong RA Swedlund, Bradley RA Teng, David H.-F. RA Tavtigian, Sean V. RT "Identification of a candidate tumour suppressor gene, MMAC1, at RT chromosome 10q23.3 that is mutated in multiple advanced cancers."; RL Nat. Genet. 15:356-362(1997). // RX PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001; RA Azari, Shahram RA Ahmadi, Nahid RA Jeddi-Tehrani, Mahmood RA Shokri, Fazel RT "Profiling and authentication of human cell lines using short tandem RT repeat (STR) loci: report from the National Cell Bank of Iran."; RL Biologicals 35:195-202(2007). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=14614447; DOI=10.1038/sj.onc.1207198; RA Wischhusen, Jorg RA Naumann, Ulrike RA Ohgaki, Hiroko RA Rastinejad, Farzan RA Weller, Michael RT "CP-31398, a novel p53-stabilizing agent, induces p53-dependent and RT p53-independent glioma cell death."; RL Oncogene 22:8233-8245(2003). // RX PubMed=11351043; DOI=10.1038/labinvest.3780280; RA Hui, Angela Bik-Yu RA Lo, Kwok-Wai RA Yin, Xiao-Lu RA Poon, Wai-Sang RA Ng, Ho-Keung RT "Detection of multiple gene amplifications in glioblastoma multiforme RT using array-based comparative genomic hybridization."; RL Lab. Invest. 81:717-723(2001). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=19435942; DOI=10.1215/15228517-2009-025; PMCID=PMC2743214; RA Ichimura, Koichi RA Pearson, Danita M. RA Kocialkowski, Sylvia RA Backlund, L. Magnus RA Chan, Raymond RA Jones, David T.W. RA Collins, Vincent Peter RT "IDH1 mutations are present in the majority of common adult gliomas RT but rare in primary glioblastomas."; RL Neuro-oncol. 11:341-347(2009). // RX PubMed=9220028; DOI=10.1016/S0303-7207(97)00080-4; RA Sharif, Taraneh R. RA Luo, Wei RA Sharif, Mohammed RT "Functional expression of bombesin receptor in most adult and RT pediatric human glioblastoma cell lines; role in mitogenesis and in RT stimulating the mitogen-activated protein kinase pathway."; RL Mol. Cell. Endocrinol. 130:119-130(1997). // RX PubMed=21406405; DOI=10.1158/0008-5472.CAN-10-3112; RA Grzmil, Michal RA Morin, Pier Jr. RA Lino, Maria Maddalena RA Merlo, Adrian RA Frank, Stephan RA Wang, Yu-Hua RA Moncayo, Gerald RA Hemmings, Brian Arthur RT "MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-beta RT signaling pathway in human glioblastoma."; RL Cancer Res. 71:2392-2402(2011). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX DOI=10.1007/0-306-46861-1_11; RA Ali-Osman, Francis RT "Brain tumors."; RL (In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999). // RX PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D; RA Jia, Li-Qun RA Osada, Motonobu RA Ishioka, Chikashi RA Gamo, Makio RA Ikawa, Shuntaro RA Suzuki, Takao RA Shimodaira, Hideki RA Niitani, Tomohito RA Kudo, Toshio RA Akiyama, Mitoshi RA Kimura, Narimiti RA Matsuo, Mitsuyoshi RA Mizusawa, Hiroshi RA Tanaka, Noriho RA Koyama, Hideki RA Namba, Masayoshi RA Kanamaru, Ryunosuke RA Kuroki, Toshio RT "Screening the p53 status of human cell lines using a yeast functional RT assay."; RL Mol. Carcinog. 19:243-253(1997). // RX PubMed=23637631; DOI=10.1371/journal.pgen.1003464; PMCID=PMC3636093; RA Giacomini, Craig P. RA Sun, Steven RA Varma, Sushama RA Shain, Alan Hunter RA Giacomini, Marilyn M. RA Balagtas, Jay Michael S. RA Sweeney, Robert T. RA Lai, Everett RA Del Vecchio, Catherine A. RA Forster, Andrew D. RA Clarke, Nicole RA Montgomery, Kelli D. RA Zhu, Shirley RA Wong, Albert J. RA van de Rijn, Matt RA West, Robert B. RA Pollack, Jonathan R. RT "Breakpoint analysis of transcriptional and genomic profiles uncovers RT novel gene fusions spanning multiple human cancer types."; RL PLoS Genet. 9:e1003464.1-e1003464.19(2013). // RX PubMed=6825208; DOI=10.1093/carcin/4.2.199; RA Yarosh, Daniel B. RA Foote, Robert S. RA Mitra, Sankar RA Day, Rufus S. 3rd RT "Repair of O6-methylguanine in DNA by demethylation is lacking in Mer- RT human tumor cell strains."; RL Carcinogenesis 4:199-205(1983). // RX PubMed=15900046; DOI=10.1093/jnci/dji133; RA Mashima, Tetsuo RA Oh-hara, Tomoko RA Sato, Shigeo RA Mochizuki, Mikiko RA Sugimoto, Yoshikazu RA Yamazaki, Kanami RA Hamada, Jun-ichi RA Tada, Mitsuhiro RA Moriuchi, Tetsuya RA Ishikawa, Yuichi RA Kato, Yo RA Tomoda, Hiroshi RA Yamori, Takao RA Tsuruo, Takashi RT "p53-defective tumors with a functional apoptosome-mediated pathway: a RT new therapeutic target."; RL J. Natl. Cancer Inst. 97:765-777(2005). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=9842975; DOI=10.1002/(SICI)1097-0215(19981218)79:6<640::AID-IJC15>3.0.CO;2-Z; RA Weller, Michael RA Rieger, Johannes RA Grimmel, Cornelia RA Van Meir, Erwin G. RA De Tribolet, Nicolas RA Krajewski, Stanislaw RA Reed, John C. RA von Deimling, Andreas RA Dichgans, Johannes RT "Predicting chemoresistance in human malignant glioma cells: the role RT of molecular genetic analyses."; RL Int. J. Cancer 79:640-644(1998). // RX PubMed=7523863; DOI=10.1128/mcb.14.11.7604-7610.1994; PMCID=PMC359296; RA Pomykala, Helen M. RA Bohlander, Stefan Klaus RA Broeker, Pamela L. RA Olopade, Olufunmilayo I. RA Diaz, Manuel O. RT "Breakpoint junctions of chromosome 9p deletions in two human glioma RT cell lines."; RL Mol. Cell. Biol. 14:7604-7610(1994). // RX PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x; PMCID=PMC11159392; RA Saigusa, Kuniyasu RA Hashimoto, Naoya RA Tsuda, Hitoshi RA Yokoi, Sana RA Maruno, Motohiko RA Yoshimine, Toshiki RA Aoyagi, Masaru RA Ohno, Kikuo RA Imoto, Issei RA Inazawa, Johji RT "Overexpressed Skp2 within 5p amplification detected by array-based RT comparative genomic hybridization is associated with poor prognosis of RT glioblastomas."; RL Cancer Sci. 96:676-683(2005). // RX PubMed=16697959; DOI=10.1016/j.ccr.2006.03.030; RA Lee, Jeongwu RA Kotliarova, Svetlana RA Kotliarov, Yuri RA Li, Ai-Guo RA Su, Qin RA Donin, Nicholas Murray RA Pastorino, Sandra RA Purow, Benjamin W. RA Christopher, Neil RA Zhang, Wei RA Park, John K. RA Fine, Howard Alan RT "Tumor stem cells derived from glioblastomas cultured in bFGF and EGF RT more closely mirror the phenotype and genotype of primary tumors than RT do serum-cultured cell lines."; RL Cancer Cell 9:391-403(2006). // RX PubMed=1385192; DOI=10.1016/0531-5565(92)90007-m; RA Fleming, Timothy P. RA Matsui, Toshimitsu RA Aaronson, Stuart A. RT "Platelet-derived growth factor (PDGF) receptor activation in cell RT transformation and human malignancy."; RL Exp. Gerontol. 27:523-532(1992). // RX PubMed=833871; DOI=10.1093/jnci/58.2.209; RA Fogh, Jorgen RA Wright, William C. RA Loveless, James D. RT "Absence of HeLa cell contamination in 169 cell lines derived from RT human tumors."; RL J. Natl. Cancer Inst. 58:209-214(1977). // RX PubMed=19365568; DOI=10.1371/journal.pone.0005209; PMCID=PMC2666263; RA Bax, Dorine Arjanne RA Little, Suzanne E. RA Gaspar, Nathalie RA Perryman, Lara RA Marshall, Lynley RA Viana-Pereira, Marta RA Jones, Tania A. RA Williams, Richard D. RA Grigoriadis, Anita RA Vassal, Gilles RA Workman, Paul RA Sheer, Denise RA Reis, Rui Manuel RA Pearson, Andrew D.J. RA Hargrave, Darren RA Jones, Chris RT "Molecular and phenotypic characterisation of paediatric glioma cell RT lines as models for preclinical drug development."; RL PLoS ONE 4:e5209.1-e5209.9(2009). // RX PubMed=6954533; DOI=10.1073/pnas.79.7.2194; PMCID=PMC346157; RA Westin, Eric H. RA Gallo, Robert Charles RA Arya, Suresh K. RA Eva, Alessandra RA Souza, Lawrence M. RA Baluda, Marcel Albert RA Aaronson, Stuart A. RA Wong-Staal, Flossie RT "Differential expression of the amv gene in human hematopoietic RT cells."; RL Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982). // RX PubMed=212188; RA Todaro, George J. RA De Larco, Joseph E. RT "Growth factors produced by sarcoma virus-transformed cells."; RL Cancer Res. 38:4147-4154(1978). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=1255758; DOI=10.1093/jnci/56.2.245; RA Gonda, Matthew A. RA Aaronson, Stuart A. RA Ellmore, Nelson Wayne RA Zeve, Victor H. RA Nagashima, Kunio RT "Ultrastructural studies of surface features of human normal and tumor RT cells in tissue culture by scanning and transmission electron RT microscopy."; RL J. Natl. Cancer Inst. 56:245-263(1976). // RX PubMed=6652614; DOI=10.1016/0165-4608(83)90091-2; RA Bigner, Sandra H. RA Mark, Joachim RA Bigner, Darell Doty RT "Chromosomal composition of four permanent cultured cell lines derived RT from human gliomas."; RL Cancer Genet. Cytogenet. 10:335-349(1983). // RX PubMed=14655754; DOI=10.1111/j.1750-3639.2003.tb00479.x; PMCID=PMC8095903; RA Bahr, Oliver RA Rieger, Johannes RA Duffner, Frank RA Meyermann, Richard RA Weller, Michael RA Wick, Wolfgang RT "P-glycoprotein and multidrug resistance-associated protein mediate RT specific patterns of multidrug resistance in malignant glioma cell RT lines, but not in primary glioma cells."; RL Brain Pathol. 13:482-494(2003). // RX DOI=10.1016/B978-0-12-333530-2.50005-8; RA Nister, Monica RA Westermark, Bengt RT "Human glioma cell lines."; RL (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. 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Genet. 74:104-106(1986). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652; RA Cowley, Glenn S. RA Weir, Barbara A. RA Vazquez, Francisca RA Tamayo, Pablo RA Scott, Justine A. RA Rusin, Scott RA East-Seletsky, Alexandra RA Ali, Levi D. RA Gerath, William F.J. RA Pantel, Sarah E. RA Lizotte, Patrick Hall RA Jiang, Guo-Zhi RA Hsiao, Jessica RA Tsherniak, Aviad RA Dwinell, Elizabeth RA Aoyama, Simon RA Okamoto, Michael RA Harrington, William RA Gelfand, Ellen T. RA Green, Thomas M. RA Tomko, Mark J. RA Gopal, Shuba RA Wong, Terence C. RA Li, Hu-Bo RA Howell, Sara RA Stransky, Nicolas RA Liefeld, Ted RA Jang, Dongkeun RA Bistline, Jonathan RA Meyers, Barbara Hill RA Armstrong, Scott Allen RA Anderson, Kenneth Carl RA Stegmaier, Kimberly RA Reich, Michael RA Pellman, David RA Boehm, Jesse S. RA Mesirov, Jill P. RA Golub, Todd Robert RA Root, David E. RA Hahn, William Chun RT "Parallel genome-scale loss of function screens in 216 cancer cell RT lines for the identification of context-specific genetic RT dependencies."; RL Sci. 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RT "Cellular genes analogous to retroviral onc genes are transcribed in RT human tumour cells."; RL Nature 295:116-119(1982). // RX PubMed=30188626; DOI=10.1134/S1990519X16050072; RA Kiseleva, Liubov Nikolaevna RA Kartashev, Artem Vladimirovich RA Vartanyan, Natalia Levonovna RA Pinevich, Agniia Aleksandrovna RA Samoylovich, Marina Platonovna RT "Characteristics of A172 and T98G cell lines."; RL Tsitologiia 58:349-355(2016). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844; RA Bady, Pierre RA Diserens, Annie-Claire RA Castella, Vincent RA Kalt, Stefanie RA Heinimann, Karl RA Hamou, Marie-France RA Delorenzi, Mauro RA Hegi, Monika E. RT "DNA fingerprinting of glioma cell lines and considerations on RT similarity measurements."; RL Neuro-oncol. 14:701-711(2012). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=6256643; DOI=10.1038/288724a0; RA Day, Rufus S. 3rd RA Ziolkowski, Chuck H.J. RA Scudiero, Dominic A. RA Meyer, Sharon A. RA Lubiniecki, Anthony S. RA Girardi, Anthony Joseph RA Galloway, Sheila Margaret RA Bynum, Gaither D. RT "Defective repair of alkylated DNA by human tumour and RT SV40-transformed human cell strains."; RL Nature 288:724-727(1980). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=34036375; DOI=10.3892/mmr.2021.12172; PMCID=PMC8170197; RA Cao, Yi-Qiang RA Chai, Wen-Ying RA Wang, Yong-Gang RA Tang, Dang RA Shao, Dong-Chuan RA Song, Hai RA Long, Jiang RT "lncRNA TUG1 inhibits the cancer stem cell-like properties of RT temozolomide-resistant glioma cells by interacting with EZH2."; RL Mol. Med. Rep. 24:533.1-533.10(2021). // RX PubMed=3675803; RA Bigner, Sandra H. RA Bjerkvig, Rolf RA Laerum, Ole Didrik RA Muhlbaier, Laurence H. RA Bigner, Darell Doty RT "DNA content and chromosomes in permanent cultured cell lines derived RT from malignant human gliomas."; RL Anal. Quant. Cytol. Histol. 9:435-444(1987). // RX PubMed=10698499; DOI=10.1038/sj.onc.1203409; RA Ciesielski, Michael J. RA Fenstermaker, Robert A. RT "Oncogenic epidermal growth factor receptor mutants with tandem RT duplication: gene structure and effects on receptor function."; RL Oncogene 19:810-820(2000). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=77569; DOI=10.1111/j.1399-0039.1978.tb01259.x; RA Espmark, Jons Ake RA Ahlqvist-Roth, Lena RA Sarne, Lena RA Persson, Anita RT "Tissue typing of cells in culture. III. HLA antigens of established RT human cell lines. Attempts at typing by the mixed hemadsorption RT technique."; RL Tissue Antigens 11:279-286(1978). // RX PubMed=4357758; DOI=10.1093/jnci/51.5.1417; RA Giard, Donald J. RA Aaronson, Stuart A. RA Todaro, George J. RA Arnstein, Paul RA Kersey, John H. RA Dosik, Harvey RA Parks, Wade P. RT "In vitro cultivation of human tumors: establishment of cell lines RT derived from a series of solid tumors."; RL J. Natl. Cancer Inst. 51:1417-1423(1973). //