ID   Namalwa
AC   CVCL_0067
SY   NAMALWA; Namalwa IV; Namalva; NAMALVA; NWA; NK62a
DR   BTO; BTO_0003289
DR   CLO; CLO_0007939
DR   EFO; EFO_0002246
DR   CLDB; cl3633
DR   CLDB; cl3634
DR   CLDB; cl3635
DR   CLDB; cl3636
DR   CLDB; cl3637
DR   AddexBio; C0003013/4670
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-1432
DR   BCRC; 60553
DR   BCRJ; 0181
DR   BioSample; SAMN01821584
DR   BioSample; SAMN01821651
DR   BioSample; SAMN03473179
DR   BioSample; SAMN10988039
DR   cancercelllines; CVCL_0067
DR   CCRID; 3101HUMTCHu75
DR   Cell_Model_Passport; SIDM00641
DR   CGH-DB; 9201-4
DR   ChEMBL-Cells; CHEMBL3307288
DR   ChEMBL-Targets; CHEMBL614049
DR   CLS; 300439
DR   Cosmic; 929814
DR   Cosmic; 931107
DR   Cosmic; 998717
DR   Cosmic; 1037702
DR   Cosmic; 1086329
DR   Cosmic; 1818345
DR   Cosmic; 2701743
DR   Cosmic; 2814540
DR   Cosmic; 2823076
DR   Cosmic-CLP; 908159
DR   DepMap; ACH-000944
DR   DSMZ; ACC-24
DR   DSMZCellDive; ACC-24
DR   ECACC; 87060801
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   ENCODE; ENCBS040JOT
DR   ENCODE; ENCBS105ISO
DR   ENCODE; ENCBS499IUK
DR   ENCODE; ENCBS566UPJ
DR   GDSC; 908159
DR   GEO; GSM99385
DR   GEO; GSM119534
DR   GEO; GSM499728
DR   GEO; GSM499734
DR   GEO; GSM862851
DR   GEO; GSM862852
DR   GEO; GSM862853
DR   GEO; GSM862854
DR   GEO; GSM862855
DR   GEO; GSM862856
DR   GEO; GSM862857
DR   GEO; GSM862858
DR   GEO; GSM888424
DR   GEO; GSM907523
DR   GEO; GSM1374695
DR   GEO; GSM1670143
DR   IARC_TP53; 175
DR   IGRhCellID; NAMALWA
DR   IZSLER; BS TCL 47
DR   JCRB; IFO50040
DR   LiGeA; CCLE_320
DR   LINCS_LDP; LCL-2022
DR   Lonza; 73
DR   NCBI_Iran; C126
DR   PharmacoDB; NAMALWA_981_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0067
DR   PubChem_Cell_line; CVCL_0067
DR   RCB; RCB0445
DR   TOKU-E; 2556
DR   Wikidata; Q54907447
RX   DOI=10.11418/jtca1981.15.4_211;
RX   PubMed=170370;
RX   PubMed=216485;
RX   PubMed=464569;
RX   PubMed=1325212;
RX   PubMed=1339415;
RX   PubMed=1915267;
RX   PubMed=2052620;
RX   PubMed=2415623;
RX   PubMed=2580922;
RX   PubMed=2830981;
RX   PubMed=2985879;
RX   PubMed=2995175;
RX   PubMed=2998993;
RX   PubMed=3026973;
RX   PubMed=3080238;
RX   PubMed=3100061;
RX   PubMed=3159941;
RX   PubMed=3874327;
RX   PubMed=3997900;
RX   PubMed=4122458;
RX   PubMed=4347031;
RX   PubMed=4364259;
RX   PubMed=6231253;
RX   PubMed=6286763;
RX   PubMed=6811418;
RX   PubMed=7316467;
RX   PubMed=7849311;
RX   PubMed=8176200;
RX   PubMed=8344493;
RX   PubMed=8402660;
RX   PubMed=8515068;
RX   PubMed=8558920;
RX   PubMed=8568269;
RX   PubMed=9192833;
RX   PubMed=9473234;
RX   PubMed=9973220;
RX   PubMed=10739008;
RX   PubMed=11226526;
RX   PubMed=12145705;
RX   PubMed=16960149;
RX   PubMed=18357372;
RX   PubMed=20215515;
RX   PubMed=20454443;
RX   PubMed=21269460;
RX   PubMed=22460905;
RX   PubMed=22885699;
RX   PubMed=24590883;
RX   PubMed=25355872;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25960936;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=29892436;
RX   PubMed=30285677;
RX   PubMed=30629668;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=35839778;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=Namalwa
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: African; Kenyan.
CC   Virology: Contains 2 integrated copies of EBV genome on chromosome 1.
CC   Virology: Infected by squirrel monkey retrovirus (SMRV) (PubMed=1339415; PubMed=20454443).
CC   Doubling time: 18 hours (PubMed=8402660); ~20-30 hours (DSMZ=ACC-24).
CC   HLA typing: A*29:02,66:02; B*57:03,58:01; C*07:01,15:05; DQA1*01:02,03:02; DQB1*02:01,06:02; DRB1*07:01,15:03 (PubMed=25960936).
CC   HLA typing: A*03:01,68:02; B*07:02,49:01; C*04:01,07:01; DQA1*01:02,03:02; DQB1*03:02,06:02; DRB1*04:05,15:03 (PubMed=26589293).
CC   HLA typing: A*03:01:01,20:02:01; B*07:02:01,01:01:01; C*07:01:02,07:02:01; DPB1*01:01:01,02:01:02; DQA1*01:02:01,03:03:01; DQB1*03:02:01.06:02:01; DRB1*04:05:01,15:03:01 (CLS=300439).
CC   Microsatellite instability: Instable (MSI-low) (PubMed=10739008; PubMed=11226526; Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=2052620; PubMed=8344493; PubMed=8402660; Cosmic-CLP=908159; DepMap=ACH-000944).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq virome analysis.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=94.65%; Native American=0%; East Asian, North=1.43%; East Asian, South=0%; South Asian=0%; European, North=0%; European, South=3.91% (PubMed=30894373).
CC   Caution: Indicated to have an additional TP53 p.Arg248Trp (c.742C>T) mutation according to PubMed=2052620, but not confirmed by other references or by CCLE and Cosmic-CLP.
CC   Misspelling: NAMALLA; Cosmic=998717.
CC   Discontinued: RCB; RCB0445; true.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): AddexBio=C0003013/4670; ATCC=CRL-1432; CLS=300439; Cosmic-CLP=908159; DSMZ=ACC-24; ECACC=87060801; JCRB=IFO50040; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 9
ST   D18S51: 15
ST   D19S433: 14,18
ST   D21S11: 27,28
ST   D2S1338: 17,21
ST   D3S1358: 16
ST   D5S818: 12,13
ST   D7S820: 11
ST   D8S1179: 13,15
ST   FGA: 22
ST   Penta D: 8,13
ST   Penta E: 5,15
ST   TH01: 7,9.3
ST   TPOX: 6,11
ST   vWA: 14
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Children
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 49
CH   CVCL_VK71 ! F2N78
CH   CVCL_1431 ! MUTZ-1
CH   CVCL_4Y60 ! Namalwa KJM-1
CH   CVCL_1838 ! Namalwa.CSN/70
CH   CVCL_1839 ! Namalwa.IPN/45
CH   CVCL_1840 ! Namalwa.KN2
CH   CVCL_1841 ! Namalwa.PNT
CH   CVCL_KU34 ! Namalwa/21V
CH   CVCL_KU33 ! Namalwa/MDR1
CH   CVCL_ZI18 ! NAMPUT
CH   CVCL_U821 ! NAT-30
//
RX   PubMed=2052620; DOI=10.1073/pnas.88.12.5413; PMCID=PMC51883;
RA   Gaidano, Gianluca
RA   Ballerini, Paola
RA   Gong, Jerry Z.
RA   Inghirami, Giorgio
RA   Neri, Antonino
RA   Newcomb, Elizabeth W.
RA   Magrath, Ian Trevor
RA   Knowles, Daniel M. 2nd
RA   Dalla-Favera, Riccardo
RT   "p53 mutations in human lymphoid malignancies: association with
RT   Burkitt lymphoma and chronic lymphocytic leukemia.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:5413-5417(1991).
//
RX   PubMed=20454443; DOI=10.1155/2010/904767; PMCID=PMC2861168;
RA   Uphoff, Cord C.
RA   Denkmann, Sabine A.
RA   Steube, Klaus G.
RA   Drexler, Hans Gunther
RT   "Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human
RT   and other primate cell lines.";
RL   J. Biomed. Biotechnol. 2010:904767.1-904767.23(2010).
//
RX   PubMed=170370; DOI=10.1099/0022-1317-28-2-207;
RA   Adams, Alice
RA   Strander, Hans
RA   Cantell, Kari
RT   "Sensitivity of the Epstein-Barr virus transformed human lymphoid cell
RT   lines to interferon.";
RL   J. Gen. Virol. 28:207-217(1975).
//
RX   PubMed=4347031; DOI=10.1093/jnci/48.1.87;
RA   Hewetson, John F.
RA   Gothoskar, Balwant
RA   Klein, George
RT   "Radioiodine-labeled antibody test for the detection of membrane
RT   antigens associated with Epstein-Barr virus.";
RL   J. Natl. Cancer Inst. 48:87-94(1972).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//
RX   PubMed=24590883; DOI=10.1002/gcc.22161;
RA   Murga Penas, Eva-Maria
RA   Schilling, Georgia
RA   Behrmann, Petra
RA   Klokow, Marianne
RA   Vettorazzi, Eik
RA   Bokemeyer, Carsten
RA   Dierlamm, Judith
RT   "Comprehensive cytogenetic and molecular cytogenetic analysis of 44
RT   Burkitt lymphoma cell lines: secondary chromosomal changes
RT   characterization, karyotypic evolution, and comparison with primary
RT   samples.";
RL   Genes Chromosomes Cancer 53:497-515(2014).
//
RX   PubMed=2580922; DOI=10.1089/jir.1985.5.65;
RA   Feinstein, Sabine
RA   Traub, Abraham
RA   Lazar, Arye
RA   Mizrahi, Avshalom
RA   Teitz, Yael
RT   "Studies on cell binding and internalization of human lymphoblastoid
RT   (Namalva) interferon.";
RL   J. Interferon Res. 5:65-76(1985).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=9973220;
RA   Gutierrez, Marina I.
RA   Cherney, Barry W.
RA   Hussain, Azhar
RA   Mostowski, Howard S.
RA   Tosato, Giovanna
RA   Magrath, Ian Trevor
RA   Bhatia, Kishor G.
RT   "Bax is frequently compromised in Burkitt's lymphomas with
RT   irreversible resistance to Fas-induced apoptosis.";
RL   Cancer Res. 59:696-703(1999).
//
RX   PubMed=3997900; DOI=10.1016/S0092-1157(85)80024-x;
RA   Whitaker, A.M.
RT   "The chromosomes of the Namalwa cell line.";
RL   J. Biol. Stand. 13:173-175(1985).
//
RX   PubMed=9473234; DOI=10.1182/blood.V91.5.1680;
RA   Klangby, Ulf
RA   Okan, Ismail
RA   Magnusson, Kristinn Petur
RA   Wendland, Martin
RA   Lind, Peter
RA   Wiman, Klas G.
RT   "p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a
RT   mRNA and protein expression in Burkitt's lymphoma.";
RL   Blood 91:1680-1687(1998).
//
RX   PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1;
RA   Inoue, Kaoru
RA   Kohno, Takashi
RA   Takakura, Satoshi
RA   Hayashi, Yasuhide
RA   Mizoguchi, Hideaki
RA   Yokota, Jun
RT   "Corrigendum to 'Frequent microsatellite instability and BAX mutations
RT   in T cell acute lymphoblastic leukemia cell lines' Leukemia Research 24
RT   (2000), 255-262.";
RL   Leuk. Res. 25:275-278(2001).
//
RX   PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- III.
RT   Beta-hexosaminidase (E.C. 3.2.1.30).";
RL   Leuk. Res. 9:549-559(1985).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=464569; DOI=10.1128/AAC.15.3.420; PMCID=PMC352676;
RA   Klein, Frederick
RA   Ricketts, Robert T.
RA   Jones, William I.
RA   DeArmon, Ira A.
RA   Temple, Matthew J.
RA   Zoon, Kathryn Christine
RA   Bridgen, Pamela J.
RT   "Large-scale production and concentration of human lymphoid
RT   interferon.";
RL   Antimicrob. Agents Chemother. 15:420-427(1979).
//
RX   PubMed=8558920;
RA   Dirks, Wilhelm Gerhard
RA   Zaborski, Margarete
RA   Jager, Kathrin
RA   Challier, Cecile
RA   Shiota, Mami
RA   Quentmeier, Hilmar
RA   Drexler, Hans Gunther
RT   "The (2;5)(p23;q35) translocation in cell lines derived from malignant
RT   lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.";
RL   Leukemia 10:142-149(1996).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, Agda Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=8344493; DOI=10.1096/fasebj.7.10.8344493;
RA   Bhatia, Kishor G.
RA   Goldschmidts, Walter
RA   Gutierrez, Marina I.
RA   Gaidano, Gianluca
RA   Dalla-Favera, Riccardo
RA   Magrath, Ian Trevor
RT   "Hemi- or homozygosity: a requirement for some but not other p53
RT   mutant proteins to accumulate and exert a pathogenetic effect.";
RL   FASEB J. 7:951-956(1993).
//
RX   PubMed=6811418; DOI=10.1016/S0171-2985(11)80031-8;
RA   Spira, Gad
RA   Koide, Norio
RA   Aman, Pierre
RA   Ber, Rosalie
RA   Klein, George
RT   "Truncated mu chain in a Burkitt lymphoma line (P3HR-1) and its fate
RT   in various hemapoietic somatic cell hybrids.";
RL   Immunobiology 162:199-209(1982).
//
RX   PubMed=1339415; DOI=10.1002/ijc.2910520320;
RA   Middleton, Peter Gelder
RA   Miller, S.
RA   Ross, James A.
RA   Steel, Christopher Michael
RA   Guy, Keith
RT   "Insertion of SMRV-H viral DNA at the c-myc gene locus of a BL cell
RT   line and presence in established cell lines.";
RL   Int. J. Cancer 52:451-454(1992).
//
RX   PubMed=29892436; DOI=10.1098/rsos.172472; PMCID=PMC5990783;
RA   Shioda, Setsuko
RA   Kasai, Fumio
RA   Watanabe, Ken
RA   Kawakami, Kohei
RA   Ohtani, Azusa
RA   Iemura, Masashi
RA   Ozawa, Midori
RA   Arakawa, Akemi
RA   Hirayama, Noriko
RA   Kawaguchi, Eiko
RA   Tano, Tomoko
RA   Miyata, Sayaka
RA   Satoh, Motonobu
RA   Shimizu, Norio
RA   Kohara, Arihiro
RT   "Screening for 15 pathogenic viruses in human cell lines registered at
RT   the JCRB Cell Bank: characterization of in vitro human cells by viral
RT   infection.";
RL   R. Soc. Open Sci. 5:172472-172472(2018).
//
RX   PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- 1.
RT   Carboxylic esterase.";
RL   Leuk. Res. 9:209-229(1985).
//
RX   PubMed=216485;
RA   Higgins, Norman Patrick
RA   Strauss, Bernard S.
RT   "Differences in the ability of human lymphoblastoid lines to exclude
RT   bromodeoxyuridine and in their sensitivity to methyl methanesulfonate
RT   and to incorporated [3H]thymidine.";
RL   Cancer Res. 39:312-320(1979).
//
RX   DOI=10.11418/jtca1981.15.4_211;
RA   Matsuo, Yoshinobu
RA   Okochi, Ayumi
RA   Ariyasu, Toshio
RA   Iimura, Emi
RA   Ohno, Tadao
RT   "Identification of cell lines with variable numbers of tandem repeat
RT   (VNTR) amplified by polymerase chain reaction.";
RL   Tissue Cult. Res. Commun. 15:211-219(1996).
//
RX   PubMed=6286763; DOI=10.4049/jimmunol.129.3.1336;
RA   Benjamin, David
RA   Magrath, Ian Trevor
RA   Maguire, Robert T.
RA   Janus, Carol
RA   Todd-Kulikowsk, Heather D.
RA   Parsons, Robert G.
RT   "Immunoglobulin secretion by cell lines derived from African and
RT   American undifferentiated lymphomas of Burkitt's and non-Burkitt's
RT   type.";
RL   J. Immunol. 129:1336-1342(1982).
//
RX   PubMed=8568269; DOI=10.4049/jimmunol.156.4.1626;
RA   Benjamin, David
RA   Sharma, Venkatanarayanan
RA   Kubin, Marek
RA   Klein, Jared L.
RA   Sartori, Alexandrina
RA   Holliday, Jane
RA   Trinchieri, Giorgio
RT   "IL-12 expression in AIDS-related lymphoma B cell lines.";
RL   J. Immunol. 156:1626-1637(1996).
//
RX   PubMed=16960149; DOI=10.1182/blood-2006-06-026500;
RA   Mestre-Escorihuela, Cinta
RA   Rubio-Moscardo, Fanny
RA   Richter, Jose A.
RA   Siebert, Reiner
RA   Climent, Joan
RA   Fresquet, Vicente
RA   Beltran, Elena
RA   Agirre, Xabier
RA   Marugan, Isabel
RA   Marin, Miguel
RA   Rosenwald, Andreas
RA   Sugimoto, Kei-ji
RA   Wheat, Luise M.
RA   Karran, E. Loraine
RA   Garcia Garcia, Juan Fernando
RA   Sanchez-Verde, Lydia
RA   Prosper, Felipe
RA   Staudt, Louis Michael
RA   Pinkel, Daniel
RA   Dyer, Martin John Swinnerton
RA   Martinez-Climent, Jose Angel
RT   "Homozygous deletions localize novel tumor suppressor genes in B-cell
RT   lymphomas.";
RL   Blood 109:271-280(2007).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893;
RA   Stranks, Gail
RA   Height, Susan E.
RA   Mitchell, Paul
RA   Jadayel, Dalal Mouneimne
RA   Yuille, Martin A.R.
RA   De Lord, Corinne F.M.
RA   Clutterbuck, Robyn D.
RA   Treleaven, Jennie G.
RA   Powles, Ray Leonard
RA   Nacheva, Elisabeth
RA   Oscier, David G.
RA   Karpas, Abraham
RA   Lenoir, Gilbert Marcel
RA   Smith, Stephen D.
RA   Millar, John L.
RA   Catovsky, Daniel
RA   Dyer, Martin John Swinnerton
RT   "Deletions and rearrangement of CDKN2 in lymphoid malignancy.";
RL   Blood 85:893-901(1995).
//
RX   PubMed=9192833;
RA   Cherney, Barry W.
RA   Bhatia, Kishor G.
RA   Sgadari, Cecilia
RA   Gutierrez, Marina I.
RA   Mostowski, Howard S.
RA   Pike, Sandra Easterly
RA   Gupta, Ghanshyam
RA   Magrath, Ian Trevor
RA   Tosato, Giovanna
RT   "Role of the p53 tumor suppressor gene in the tumorigenicity of
RT   Burkitt's lymphoma cells.";
RL   Cancer Res. 57:2508-2515(1997).
//
RX   PubMed=2415623; DOI=10.4049/jimmunol.136.1.320;
RA   Goldmacher, Victor S.
RA   Lambert, John M.
RA   Young, Annie Yau
RA   Anderson, Jean
RA   Tinnel, Nancy L.
RA   Kornacki, Mary
RA   Ritz, Jerome
RA   Blattler, Walter A.
RT   "Expression of the common acute lymphoblastic leukemia antigen (CALLA)
RT   on the surface of individual cells of human lymphoblastoid lines.";
RL   J. Immunol. 136:320-325(1986).
//
RX   PubMed=3080238;
RA   Sieverts, Hauke
RA   Alabaster, Oliver
RA   Goldschmidts, Walter
RA   Magrath, Ian Trevor
RT   "Expression of surface antigens during the cell cycle in different
RT   growth phases of American and African Burkitt's lymphoma cell lines.";
RL   Cancer Res. 46:1182-1188(1986).
//
RX   PubMed=4122458; DOI=10.1002/ijc.2910100108;
RA   Klein, George
RA   Dombos, Laszlo
RA   Gothoskar, Balwant
RT   "Sensitivity of Epstein-Barr virus (EBV) producer and non-producer
RT   human lymphoblastoid cell lines to superinfection with EB-virus.";
RL   Int. J. Cancer 10:44-57(1972).
//
RX   PubMed=8176200; DOI=10.4049/jimmunol.152.10.4749;
RA   Benjamin, David
RA   Sharma, Venkatanarayanan
RA   Knobloch, Thomas J.
RA   Armitage, Richard J.
RA   Dayton, Mark A.
RA   Goodwin, Raymond G.
RT   "B cell IL-7. Human B cell lines constitutively secrete IL-7 and
RT   express IL-7 receptors.";
RL   J. Immunol. 152:4749-4757(1994).
//
RX   PubMed=12145705; DOI=10.1038/sj.leu.2402519;
RA   Langerak, Anton W.
RA   Moreau, Elisabeth J.
RA   van Gastel-Mol, Ellen J.
RA   van der Burg, Mirjam
RA   van Dongen, Jacobus Johannes Maria
RT   "Detection of clonal EBV episomes in lymphoproliferations as a
RT   diagnostic tool.";
RL   Leukemia 16:1572-1573(2002).
//
RX   PubMed=3100061; DOI=10.1016/0008-8749(86)90099-7;
RA   Benjamin, David
RA   Bazar, Leonard S.
RA   Wallace, Brett
RA   Jacobson, Robert J.
RT   "Heterogeneity of B-cell growth factor receptor reactivity in healthy
RT   donors and in patients with chronic lymphatic leukemia: relationship
RT   to B-cell-derived lymphokines.";
RL   Cell. Immunol. 103:394-408(1986).
//
RX   PubMed=1915267; DOI=10.1002/j.1460-2075.1991.tb07837.x; PMCID=PMC452998;
RA   Farrell, Paul J.
RA   Allan, Gordon J.
RA   Shanahan, Frances
RA   Vousden, Karen Heather
RA   Crook, Tim
RT   "p53 is frequently mutated in Burkitt's lymphoma cell lines.";
RL   EMBO J. 10:2879-2887(1991).
//
RX   PubMed=25355872; DOI=10.1128/JVI.02570-14; PMCID=PMC4301145;
RA   Cao, Su-Bing
RA   Strong, Michael J.
RA   Wang, Xia
RA   Moss, Walter N.
RA   Concha, Monica
RA   Lin, Zhen
RA   O'Grady, Tina
RA   Baddoo, Melody
RA   Fewell, Claire
RA   Renne, Rolf
RA   Flemington, Erik K.
RT   "High-throughput RNA sequencing-based virome analysis of 50 lymphoma
RT   cell lines from the Cancer Cell Line Encyclopedia project.";
RL   J. Virol. 89:713-729(2015).
//
RX   PubMed=2995175;
RA   Wurm, Florian Maria
RA   Polastri, Gian D.
RA   Hilfenhaus, Joachim
RA   Harth, Holger
RA   Zankl, Heinrich
RT   "Long term cultivation of Namalva cells for interferon production:
RT   stable cytogenetic markers for identification of cells in spite of
RT   drastic chromosomal variation.";
RL   Dev. Biol. Stand. 60:393-403(1985).
//
RX   PubMed=6231253; DOI=10.1002/ijc.2910330407;
RA   Ehlin-Henriksson, Barbro
RA   Klein, George
RT   "Distinction between Burkitt lymphoma subgroups by monoclonal
RT   antibodies: relationships between antigen expression and type of
RT   chromosomal translocation.";
RL   Int. J. Cancer 33:459-463(1984).
//
RX   PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786;
RA   Tan, Kar-Tong
RA   Ding, Ling-Wen
RA   Sun, Qiao-Yang
RA   Lao, Zhen-Tang
RA   Chien, Wenwen
RA   Ren, Xi
RA   Xiao, Jin-Fen
RA   Loh, Xin-Yi
RA   Xu, Liang
RA   Lill, Michael
RA   Mayakonda, Anand
RA   Lin, De-Chen
RA   Yang, Henry He
RA   Koeffler, Harold Phillip
RT   "Profiling the B/T cell receptor repertoire of lymphocyte derived cell
RT   lines.";
RL   BMC Cancer 18:940.1-940.13(2018).
//
RX   PubMed=4364259; DOI=10.1002/ijc.2910110210;
RA   Klein, George
RA   Dombos, Laszlo
RT   "Relationship between the sensitivity of EBV-carrying lymphoblastoid
RT   lines to superinfection and the inducibility of the resident viral
RT   genome.";
RL   Int. J. Cancer 11:327-337(1973).
//
RX   PubMed=8402660;
RA   O'Connor, Patrick M.
RA   Jackman, Joany
RA   Jondle, Daniel
RA   Bhatia, Kishor G.
RA   Magrath, Ian Trevor
RA   Kohn, Kurt W.
RT   "Role of the p53 tumor suppressor gene in cell cycle arrest and
RT   radiosensitivity of Burkitt's lymphoma cell lines.";
RL   Cancer Res. 53:4776-4780(1993).
//
RX   PubMed=22885699; DOI=10.1038/nature11378; PMCID=PMC3609867;
RA   Schmitz, Roland
RA   Young, Ryan M.
RA   Ceribelli, Michele
RA   Jhavar, Sameer
RA   Xiao, Wen-Ming
RA   Zhang, Mei-Li
RA   Wright, George
RA   Shaffer, Arthur L. 3rd
RA   Hodson, Daniel James
RA   Buras, Eric
RA   Liu, Xue-Lu
RA   Powell, John I.
RA   Yang, Yan-Dan
RA   Xu, Wei-Hong
RA   Zhao, Hong
RA   Kohlhammer, Holger
RA   Rosenwald, Andreas
RA   Kluin, Philip M.
RA   Muller-Hermelink, Hans-Konrad
RA   Ott, German
RA   Gascoyne, Randy D.
RA   Connors, Joseph M.
RA   Rimsza, Lisa M.
RA   Campo, Elias
RA   Jaffe, Elaine Sarkin
RA   Delabie, Jan
RA   Smeland, Erlend Bremertun
RA   Ogwang, Martin David
RA   Reynolds, Steven J.
RA   Fisher, Richard I.
RA   Braziel, Rita Merle
RA   Tubbs, Raymond Roy
RA   Cook, James R.
RA   Weisenburger, Dennis D.
RA   Chan, Wing-Chung
RA   Pittaluga, Stefania
RA   Wilson, Wesley
RA   Waldmann, Thomas Alexander
RA   Rowe, Martin
RA   Mbulaiteye, Sam M.
RA   Rickinson, Alan Bernard
RA   Staudt, Louis Michael
RT   "Burkitt lymphoma pathogenesis and therapeutic targets from structural
RT   and functional genomics.";
RL   Nature 490:116-120(2012).
//
RX   PubMed=2998993;
RA   Steel, Christopher Michael
RA   Morten, John E.N.
RA   Foster, Michael E.
RT   "The cytogenetics of human B lymphoid malignancy: studies in Burkitt's
RT   lymphoma and Epstein-Barr virus-transformed lymphoblastoid cell
RT   lines.";
RL   IARC Sci. Publ. 60:265-292(1985).
//
RX   PubMed=18357372; DOI=10.3892/or.19.4.889;
RA   Pop, Iliodora
RA   Pop, Laurentiu
RA   Vitetta, Ellen S.
RA   Ghetie, Maria-Ana
RT   "Generation of multidrug resistant lymphoma cell lines stably
RT   expressing P-glycoprotein.";
RL   Oncol. Rep. 19:889-895(2008).
//
RX   PubMed=1325212; DOI=10.1182/blood.V80.5.1289.1289;
RA   Benjamin, David
RA   Knobloch, Thomas J.
RA   Dayton, Mark A.
RT   "Human B-cell interleukin-10: B-cell lines derived from patients with
RT   acquired immunodeficiency syndrome and Burkitt's lymphoma
RT   constitutively secrete large quantities of interleukin-10.";
RL   Blood 80:1289-1298(1992).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura Eleanor
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=3026973; DOI=10.1002/ijc.2910390215;
RA   Ehlin-Henriksson, Barbro
RA   Manneborg-Sandlund, Agneta
RA   Klein, George
RT   "Expression of B-cell-specific markers in different Burkitt lymphoma
RT   subgroups.";
RL   Int. J. Cancer 39:211-218(1987).
//
RX   PubMed=8515068; DOI=10.4049/jimmunol.150.12.5418;
RA   Jain, Vinay K.
RA   Judde, Jean-Gabriel
RA   Max, Edward E.
RA   Magrath, Ian Trevor
RT   "Variable IgH chain enhancer activity in Burkitt's lymphomas suggests
RT   an additional, direct mechanism of c-myc deregulation.";
RL   J. Immunol. 150:5418-5428(1993).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30629668; DOI=10.1371/journal.pone.0210404; PMCID=PMC6328144;
RA   Uphoff, Cord C.
RA   Pommerenke, Claudia
RA   Denkmann, Sabine A.
RA   Drexler, Hans Gunther
RT   "Screening human cell lines for viral infections applying RNA-Seq data
RT   analysis.";
RL   PLoS ONE 14:e0210404.1-e0210404.22(2019).
//
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17; PMCID=PMC3039570;
RA   Burkard, Thomas R.
RA   Planyavsky, Melanie
RA   Kaupe, Ines
RA   Breitwieser, Florian P.
RA   Burckstummer, Tilmann
RA   Bennett, Keiryn L.
RA   Superti-Furga, Giulio
RA   Colinge, Jacques
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17.1-17.13(2011).
//
RX   PubMed=2830981; DOI=10.1016/0092-8674(88)90530-2;
RA   Lawrence, Jeanne Bentley
RA   Villnave, Carol A.
RA   Singer, Robert H.
RT   "Sensitive, high-resolution chromatin and chromosome mapping in situ:
RT   presence and orientation of two closely integrated copies of EBV in a
RT   lymphoma line.";
RL   Cell 52:51-61(1988).
//
RX   PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981;
RA   Boegel, Sebastian
RA   Lower, Martin
RA   Bukur, Thomas
RA   Sahin, Ugur
RA   Castle, John C.
RT   "A catalog of HLA type, HLA expression, and neo-epitope candidates in
RT   human cancer cell lines.";
RL   OncoImmunology 3:e954893.1-e954893.12(2014).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4;
RA   Inoue, Kaoru
RA   Kohno, Takashi
RA   Takakura, Satoshi
RA   Hayashi, Yasuhide
RA   Mizoguchi, Hideaki
RA   Yokota, Jun
RT   "Frequent microsatellite instability and BAX mutations in T cell acute
RT   lymphoblastic leukemia cell lines.";
RL   Leuk. Res. 24:255-262(2000).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid
RT   phosphatase.";
RL   Leuk. Res. 9:537-548(1985).
//
RX   PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x;
RA   Povey, Susan
RA   Jeremiah, Stephen
RA   Arthur, Elizabeth
RA   Steel, C. Michael
RA   Klein, George
RT   "Differences in genetic stability between human cell lines from
RT   patients with and without lymphoreticular malignancy.";
RL   Ann. Hum. Genet. 44:119-133(1980).
//