ID WM115 AC CVCL_0040 SY WM-115; WM 115; WM115F; WM115-mel; WM115mel; WC00079 DR BTO; BTO_0003075 DR CLO; CLO_0009613 DR EFO; EFO_0002390 DR CLDB; cl4727 DR CLDB; cl4728 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; CRL-1675 DR BioGRID_ORCS_Cell_line; 345 DR BioSample; SAMN10987773 DR cancercelllines; CVCL_0040 DR Cell_Model_Passport; SIDM01000 DR CGH-DB; 9323-4 DR ChEMBL-Cells; CHEMBL3308813 DR ChEMBL-Targets; CHEMBL1075611 DR Coriell; WC00079 DR Cosmic; 886835 DR Cosmic; 888868 DR Cosmic; 897480 DR Cosmic; 905236 DR Cosmic; 909784 DR Cosmic; 932717 DR Cosmic; 972277 DR Cosmic; 1155268 DR Cosmic; 1155547 DR Cosmic; 1238102 DR Cosmic; 1238104 DR Cosmic-CLP; 909784 DR DepMap; ACH-000304 DR ECACC; 91061232 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR EGA; EGAS00001002554 DR ESTDAB; ESTDAB-066 DR GDSC; 909784 DR GEO; GSM109022 DR GEO; GSM827472 DR GEO; GSM887735 DR GEO; GSM888830 DR GEO; GSM1670576 DR GEO; GSM7701424 DR GEO; GSM7701435 DR IARC_TP53; 21271 DR IARC_TP53; 24992 DR IGRhCellID; WM115 DR IZSLER; BS TCL 74 DR LiGeA; CCLE_370 DR LINCS_HMS; 50567 DR LINCS_LDP; LCL-1260 DR Lonza; 584 DR PharmacoDB; WM115_1662_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_0040 DR PubChem_Cell_line; CVCL_0040 DR Rockland; WM115-01-0001 DR Wikidata; Q54994157 RX PubMed=2253310; RX PubMed=3020539; RX PubMed=3856042; RX PubMed=4053039; RX PubMed=11121133; RX PubMed=15009714; RX PubMed=15467732; RX PubMed=15592718; RX PubMed=16827748; RX PubMed=16957166; RX PubMed=18632627; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=21424129; RX PubMed=22460905; RX PubMed=25485619; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; WW Info; HPA; -; https://www.proteinatlas.org/learn/cellines WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: Human Protein Atlas, Cell Atlas panel. CC Part of: MD Anderson Cell Lines Project. CC Part of: Wistar Institute melanoma cell line collection. CC Population: Caucasian. CC HLA typing: A*02:01,29:02; B*13:02,44:03:01; C*06:02,16:01; DPB1*02:01:02,02:01:02; DQB1*02:01,02:01; DRB1*07:01,07:01 (PubMed=15592718). CC HLA typing: A*02:01,29:02; B*13:02,44:03; C*06:02,16:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (Wistar). CC Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (Wistar). CC Sequence variation: Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Hemizygous (Wistar). CC Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Asp (c.1799_1800delTGinsAT); ClinVar=VCV000375939; Zygosity=Heterozygous (PubMed=15009714; PubMed=15467732; Wistar). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Expression; Large antibody panel staining analysis. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0%; Native American=0.17%; East Asian, North=0%; East Asian, South=0%; South Asian=0.85%; European, North=67.47%; European, South=31.51% (PubMed=30894373). CC Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: CSF1PO: 11,12->12, D18S51: 17->17,21 and D8S1179: 8,13->13,15. CC Misspelling: WH115mel; CGH-DB=9323-4. CC Discontinued: ATCC; CRL-1675; true. CC Discontinued: Coriell; WC00079; probable. CC Discontinued: ECACC; 91061232; true. CC Derived from site: Metastatic; Right anterior leg, skin; UBERON=UBERON_0001511. ST Source(s): ATCC=CRL-1675; Cosmic-CLP=909784; ESTDAB=ESTDAB-066; Wistar ST Amelogenin: X ST CSF1PO: 12 ST D13S317: 12,13 ST D16S539: 11,12 ST D18S51: 17,21 ST D19S433: 13 ST D21S11: 29 ST D2S1338: 19 ST D3S1358: 15,18 ST D5S818: 13 ST D7S820: 8 ST D8S1179: 13,15 ST FGA: 21,23 ST TH01: 7,9 ST TPOX: 8,11 ST vWA: 15,17 DI NCIt; C3224; Melanoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) OI CVCL_L033 ! WM165-1 OI CVCL_RN55 ! WM165-2 OI CVCL_6795 ! WM239A OI CVCL_RN56 ! WM239B OI CVCL_RN57 ! WM266-1 OI CVCL_RN58 ! WM266-2 OI CVCL_RN59 ! WM266-3 OI CVCL_2765 ! WM266-4 SX Female AG 55Y CA Cancer cell line DT Created: 04-04-12; Last updated: 14-08-25; Version: 49 CH CVCL_C3N6 ! WM115-MOCK CH CVCL_C3N7 ! WM115-RAGE // RX PubMed=16957166; DOI=10.1369/jhc.6A7001.2006; PMCID=PMC3958123; RA Andersson, Ann-Catrin RA Stromberg, Sara RA Backvall, Helena RA Kampf, Caroline RA Uhlen, Mathias RA Wester, Kenneth RA Ponten, Fredrik RT "Analysis of protein expression in cell microarrays: a tool for RT antibody-based proteomics."; RL J. Histochem. Cytochem. 54:1413-1423(2006). // RX PubMed=4053039; RA Herlyn, Meenhard RA Thurin, Jan RA Balaban-Malenbaum, Gloria Brady RA Bennicelli, Jeannette L. RA Herlyn, Dorothee RA Elder, David E. RA Bondi, Edward RA Guerry, DuPont 4th RA Nowell, Peter Carey RA Clark, Wallace H. Jr. RA Koprowski, Hilary RT "Characteristics of cultured human melanocytes isolated from different RT stages of tumor progression."; RL Cancer Res. 45:5670-5676(1985). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=15467732; DOI=10.1038/sj.onc.1208152; RA Tanami, Hideaki RA Imoto, Issei RA Hirasawa, Akira RA Yuki, Yasuhiro RA Sonoda, Itaru RA Inoue, Jun RA Yasui, Kohichiroh RA Misawa-Furihata, Akiko RA Kawakami, Yutaka RA Inazawa, Johji RT "Involvement of overexpressed wild-type BRAF in the growth of RT malignant melanoma cell lines."; RL Oncogene 23:8796-8804(2004). // RX PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x; RA Hoek, Keith S. RA Schlegel, Natalie C. RA Brafford, Patricia RA Sucker, Antje RA Ugurel, Selma RA Kumar, Rajiv RA Weber, Barbara L. RA Nathanson, Katherine L. RA Phillips, Donald J. RA Herlyn, Meenhard RA Schadendorf, Dirk RA Dummer, Reinhard RT "Metastatic potential of melanomas defined by specific gene expression RT profiles with no BRAF signature."; RL Pigment Cell Res. 19:290-302(2006). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=3020539; DOI=10.1073/pnas.83.19.7197; PMCID=PMC386682; RA Westermark, Bengt RA Johnsson, Anders RA Paulsson, Ylva RA Betsholtz, Christer RA Heldin, Carl-Henrik RA Herlyn, Meenhard RA Rodeck, Ulrich RA Koprowski, Hilary RT "Human melanoma cell lines of primary and metastatic origin express RT the genes encoding the chains of platelet-derived growth factor (PDGF) RT and produce a PDGF-like growth factor."; RL Proc. Natl. Acad. Sci. U.S.A. 83:7197-7200(1986). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin K. RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=11121133; DOI=10.1046/j.1523-1747.2000.00199.x; RA Lacal, Pedro M. RA Failla, Cristina M. RA Pagani, Elena RA Odorisio, Teresa RA Schietroma, Cataldo RA Falcinelli, Sabrina RA Zambruno, Giovanna RA D'Atri, Stefania RT "Human melanoma cells secrete and respond to placenta growth factor RT and vascular endothelial growth factor."; RL J. Invest. Dermatol. 115:1000-1007(2000). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=2253310; DOI=10.1007/BF00046337; RA Herlyn, Meenhard RT "Human melanoma: development and progression."; RL Cancer Metastasis Rev. 9:101-112(1990). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, A. Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=15009714; DOI=10.1046/j.0022-202X.2004.22243.x; PMCID=PMC2586668; RA Tsao, Hensin RA Goel, Vikas RA Wu, Heng RA Yang, Guang RA Haluska, Frank G. RT "Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 RT inactivation in melanoma."; RL J. Invest. Dermatol. 122:337-341(2004). // RX PubMed=3856042; DOI=10.1093/jnci/74.2.283; RA Herlyn, Meenhard RA Balaban-Malenbaum, Gloria Brady RA Bennicelli, Jeannette L. RA Guerry, DuPont 4th RA Halaban, Ruth RA Herlyn, Dorothee RA Elder, David E. RA Maul, Gerd G. RA Steplewski, Zenon RA Nowell, Peter Carey RA Clark, Wallace H. Jr. RA Koprowski, Hilary RT "Primary melanoma cells of the vertical growth phase: similarities to RT metastatic cells."; RL J. Natl. Cancer Inst. 74:283-289(1985). // RX PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966; RA Rodriguez, Teresa RA Mendez, Rosa RA Roberts, Chrissy H. RA Ruiz-Cabello Osuna, Francisco RA Dodi, I. Anthony RA Lopez-Nevot, Miguel Angel RA Paco, Laura RA Maleno, Isabel RA Marsh, Steven G.E. RA Pawelec, Graham RA Garrido, Federico RT "High frequency of homozygosity of the HLA region in melanoma cell RT lines reveals a pattern compatible with extensive loss of RT heterozygosity."; RL Cancer Immunol. Immunother. 54:141-148(2005). // RX PubMed=21424129; DOI=10.3892/or.2011.1220; RA Manca, Antonella RA Sini, Maria Cristina RA Izzo, Francesco RA Ascierto, Paolo Antonio RA Tatangelo, Fabiana RA Botti, Gerardo RA Gentilcore, Giusy RA Capone, Marilena RA Mozzillo, Nicola RA Rozzo, Carla RA Cossu, Antonio RA Tanda, Francesco RA Palmieri, Giuseppe RT "Induction of arginosuccinate synthetase (ASS) expression affects the RT antiproliferative activity of arginine deiminase (ADI) in melanoma RT cells."; RL Oncol. Rep. 25:1495-1502(2011). // RX PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688; RA Smalley, Keiran S.M. RA Contractor, Rooha RA Nguyen, Thiennga K. RA Xiao, Min RA Edwards, Robin RA Muthusamy, Viswanathan RA King, Alastair J. RA Flaherty, Keith Thomas RA Bosenberg, Marcus W. RA Herlyn, Meenhard RA Nathanson, Katherine L. RT "Identification of a novel subgroup of melanomas with RT KIT/cyclin-dependent kinase-4 overexpression."; RL Cancer Res. 68:5743-5752(2008). //