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Cellosaurus GL261 (CVCL_Y003)

[Text version]
Cell line name GL261
Synonyms Glioma 261; GLIOMA 261; Glioma-261; GL-261
Accession CVCL_Y003
Resource Identification Initiative To cite this cell line use: GL261 (RRID:CVCL_Y003)
Comments Doubling time: ~100-120 hours (DSMZ=ACC-802).
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; HLA class I peptidome.
Omics: Proteomics; Subcellular; Cell surface.
Misspelling: GI261; Note=Occasionally.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Mouse glioblastoma (NCIt: C21938)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_E9YA (GL261-Fluc)CVCL_C9CB (GL261-Luc)CVCL_X986 (GL261-luc2)
CVCL_5I93 (GL261-Red-FLuc)CVCL_E9YB (GL261-Venus-Akaluc)CVCL_E9YC (GL261-Venus-Fluc)
CVCL_A5EJ (Quad-GL261)
Category Cancer cell line
Web pages Info; Wikipedia; -; https://en.wikipedia.org/wiki/Glioma_261
Publications

PubMed=16734735; DOI=10.1111/j.1349-7006.2006.00208.x; PMCID=PMC11159227
Tunde Szatmari, Katalin Lumniczky, Szilvia Desaknai, Stephane Trajcevski, Egon J. Hidvegi, Hirofumi Hamada, Geza Safrany;
Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy.
Cancer Sci. 97:546-553(2006)

PubMed=23248259; DOI=10.4049/jimmunol.1201557; PMCID=PMC3538956
John Robert Ohlfest, Brian M. Andersen, Adam J. Litterman, Jun-Zhe Xia, Christopher A. Pennell, Lauryn E. Swier, Andres M. Salazar, Michael R. Olin;
Vaccine injection site matters: qualitative and quantitative defects in CD8 T cells primed as a function of proximity to the tumor in a murine glioma model.
J. Immunol. 190:613-620(2013)

PubMed=23686484; DOI=10.4049/jimmunol.1203539; PMCID=PMC3680135
Adam J. Litterman, David M. Zellmer, Karen L. Grinnen, Matthew A. Hunt, Arkadiusz Z. Dudek, Andres M. Salazar, John Robert Ohlfest;
Profound impairment of adaptive immune responses by alkylating chemotherapy.
J. Immunol. 190:6259-6268(2013)

PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347
Damaris Bausch-Fluck, Andreas Hofmann, Thomas Bock, Andreas P. Frei, Ferdinando Cerciello, Andrea Jacobs, Hansjoerg Moest, Ulrich Omasits, Rebekah L. Gundry, Charles Yoon, Ralph Schiess ...Show all 20 authors... , Alexander Schmidt, Paulina Mirkowska, Anetta Svitorka Hartlova, Jennifer Eileen Van Eyk, Jean-Pierre Bourquin, Rudolf Aebersold, Kenneth R. Boheler, Peter W. Zandstra, Bernd Wollscheid; Show fewer authors
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:e0121314.1-e0121314.22(2015)

PubMed=30084848; DOI=10.1038/sdata.2018.157; PMCID=PMC6080492
Heiko Schuster, Wen-Guang Shao, Tobias Weiss, Patrick G.A. Pedrioli, Patrick Roth, Michael Weller, David S. Campbell, Eric W. Deutsch, Robert L. Moritz, Oliver Planz, Hans-Georg Rammensee ...Show all 13 authors... , Rudolf Aebersold, Etienne Caron; Show fewer authors
A tissue-based draft map of the murine MHC class I immunopeptidome.
Sci. Data 5:180157.1-180157.11(2018)

PubMed=30524896; DOI=10.1080/2162402X.2018.1501137; PMCID=PMC6279422
Vassilis Genoud, Eliana Marinari, Sergey Igorievich Nikolaev, John C. Castle, Valesca Bukur, Pierre-Yves Dietrich, Hideho Okada, Paul R. Walker;
Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models.
OncoImmunology 7:e1501137.1-e1501137.10(2018)

Cross-references
Cell line collections (Providers) BCRJ; 0299
CLS; 305225
DSMZ; ACC-802
NCI-DTP; Glioma 261
Cell line databases/resources DSMZCellDive; ACC-802
Anatomy/cell type resources BTO; BTO_0006483
Chemistry resources ChEMBL-Cells; CHEMBL4483160
ChEMBL-Targets; CHEMBL4483239
PubChem_Cell_line; CVCL_Y003
Encyclopedic resources Wikidata; Q27547979
Proteomic databases PRIDE; PXD000589
PRIDE; PXD008733
Entry history
Entry creation05-Sep-2014
Last entry update10-Apr-2025
Version number17