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Cellosaurus ICC2 (CVCL_VV27)

[Text version]
Cell line name ICC2
Accession CVCL_VV27
Resource Identification Initiative To cite this cell line use: ICC2 (RRID:CVCL_VV27)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 3 days (Direct_author_submission).
Omics: Deep exome analysis.
Miscellaneous: Doubling time and age/sex of donor from personal communication of El-Bardeesy, Nabeel.
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001842

Markers:
AmelogeninX
CSF1PO12
D3S135814
D5S81812,14
D7S8208
D8S117913
D13S3178,11
D16S53911,12
D18S5121
D21S1131,31.2
FGA22,25
Penta D10,13
Penta E14
TH018,9
TPOX9,12
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737
Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C., Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K., Greninger P., McDermott U., Garnett M.J., Jenkins R.L., Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y., Goyal L., Ferrone C.R., Zhu A.X.-X., Joung J.K., Shokat K.M., Benes C.H., El-Bardeesy N.
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VV27
Cell_Model_Passport; SIDM01804
DepMap; ACH-001842
Encyclopedic resources Wikidata; Q94313313
Entry history
Entry creation24-May-2019
Last entry update10-Sep-2024
Version number11