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Cellosaurus LM-MEL-47 (CVCL_UC52)

[Text version]
Cell line name LM-MEL-47
Synonyms LM-Mel-47; Ludwig Melbourne-MELanoma-47
Accession CVCL_UC52
Resource Identification Initiative To cite this cell line use: LM-MEL-47 (RRID:CVCL_UC52)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile from personal communication of Cardwell, Tracy.
Derived from site: Metastatic; Left inguinal lymph node; UBERON=UBERON_0001542.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23527996).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01
HLA-BB*62
HLA-CC*03:04
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO11,12
D5S8189,12
D7S8208,10
D13S3178,11
D16S5399,12
D21S1127
TH019.3
TPOX10
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=18413770; DOI=10.1158/0008-5472.CAN-07-5664
Ebert L.M., Tan B.S., Browning J., Svobodova S., Russell S.E., Kirkpatrick N.C., Gedye C., Moss D.J., Ng S.P., MacGregor D.P., Davis I.D., Cebon J.S., Chen W.-S.
The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells.
Cancer Res. 68:3001-3009(2008)

PubMed=19221743; DOI=10.1007/s00262-009-0672-0; PMCID=PMC11029848
Gedye C., Quirk J., Browning J., Svobodova S., John T., Sluka P., Dunbar P.R., Corbeil D., Cebon J.S., Davis I.D.
Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells.
Cancer Immunol. Immunother. 58:1635-1646(2009)

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UC52
Encyclopedic resources Wikidata; Q95982541
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371777
Entry history
Entry creation13-Nov-2018
Last entry update10-Sep-2024
Version number7