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Cellosaurus LM-MEL-28 (CVCL_UC36)

[Text version]
Cell line name LM-MEL-28
Synonyms LM-Mel-28; Ludwig Melbourne-MELanoma-28
Accession CVCL_UC36
Resource Identification Initiative To cite this cell line use: LM-MEL-28 (RRID:CVCL_UC36)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Doubling time: 45-55 hours (ATCC=CRL-3331).
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile from personal communication of Cardwell, Tracy.
Derived from site: Metastatic; Right inguinal lymph node; UBERON=UBERON_0001542.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23527996).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01
HLA-BB*15:01,57:01
HLA-CC*03:04,07:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3331; Direct_author_submission

Markers:
AmelogeninX
CSF1PO12
D5S81810
D7S82011
D13S3179,12
D16S53912
D21S1128,29,32
TH016,9.3
TPOX8,11
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=18413770; DOI=10.1158/0008-5472.CAN-07-5664
Ebert L.M., Tan B.S., Browning J., Svobodova S., Russell S.E., Kirkpatrick N.C., Gedye C., Moss D.J., Ng S.P., MacGregor D.P., Davis I.D., Cebon J.S., Chen W.-S.
The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells.
Cancer Res. 68:3001-3009(2008)

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3331
Cell line databases/resources cancercelllines; CVCL_UC36
Encyclopedic resources Wikidata; Q95982515
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371761
Entry history
Entry creation13-Nov-2018
Last entry update10-Sep-2024
Version number8