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Cellosaurus LM-MEL-5a (CVCL_UC20)

[Text version]
Cell line name LM-MEL-5a
Synonyms LM-Mel-5a; LM-MEL-5; Ludwig Melbourne-MELanoma-5a
Accession CVCL_UC20
Resource Identification Initiative To cite this cell line use: LM-MEL-5a (RRID:CVCL_UC20)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: Age of donor, metastatic site and STR profile from personal communication of Cardwell, Tracy.
Derived from site: Metastatic; Left axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=23527996).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01,03:01
HLA-BB*07:02,57:01
HLA-CC*06:02,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11
D5S81812
D7S82010,11
D13S31710,11
D16S5399,13
D21S1129,30
TH017
TPOX8,11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UC20
Encyclopedic resources Wikidata; Q95982554
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371745
Entry history
Entry creation13-Nov-2018
Last entry update10-Sep-2024
Version number8