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Cellosaurus GM11589 (CVCL_N186)

[Text version]
Cell line name GM11589
Synonyms GM17057; J5
Accession CVCL_N186
Resource Identification Initiative To cite this cell line use: GM11589 (RRID:CVCL_N186)
Comments Part of: Genetic Testing Reference Material (GeT-RM) samples.
Part of: Human variation panel.
Part of: Yale-Stanford Collection from NIGMS Human Genetic Cell Repository.
Population: Japanese.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 2625; CYP2D6; Simple; p.Pro34Ser (c.100C>T); ClinVar=VCV000016893; Zygosity=Heterozygous; Note=CYP2D6*10 allele (Coriell=GM17057).
HLA typing Source: PubMed=29959025
Class I
HLA-AA*24:20,33:03:01
HLA-BB*15:11:01,44:03:01
HLA-CC*03:04:01,14:03
Class II
HLA-DPDPA1*02:02:02,02:02:02
DPB1*05:01:01,05:01:01
HLA-DQDQA1*01:02:01,03:02
DQB1*03:03:02,06:02:01
HLA-DRDRB1*09:01:02,15:01:01
DRB4*01:03:02
DRB5*01:01:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=14583597; DOI=10.1152/physiolgenomics.00163.2003
Pastinen T., Sladek R., Gurd S., Sammak A., Ge B., Lepage P., Lavergne K., Villeneuve A., Gaudin T., Brandstrom H., Beck A., Verner A., Kingsley J., Harmsen E., Labuda D., Morgan K., Vohl M.-C., Naumova A.K., Sinnett D., Hudson T.J.
A survey of genetic and epigenetic variation affecting human gene expression.
Physiol. Genomics 16:184-193(2004)

PubMed=20889555; DOI=10.2353/jmoldx.2010.100090; PMCID=PMC2962854
Pratt V.M., Zehnbauer B.A., Wilson J.A., Epstein-Baak R., Babic N., Bettinotti M.P., Buller-Burckle A.M., Butz K.G., Campbell M., Civalier C., El-Badry A., Farkas D.H., Lyon E., Mandal S., McKinney J., Muralidharan K., Noll L., Sander T., Shabbeer J., Smith C.-Y.H., Telatar M., Toji L.H., Vairavan A., Vance C., Weck K.E., Wu A.H.B., Yeo K.-T.J., Zeller M., Kalman L.V.
Characterization of 107 genomic DNA reference materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1: a GeT-RM and Association for Molecular Pathology collaborative project.
J. Mol. Diagn. 12:835-846(2010)

PubMed=29959025; DOI=10.1016/j.jmoldx.2018.05.009; PMCID=PMC6939753
Bettinotti M.P., Ferriola D., Duke J.L., Mosbruger T.L., Tairis N., Jennings L., Kalman L.V., Monos D.S.
Characterization of 108 genomic DNA reference materials for 11 human leukocyte antigen loci: a GeT-RM collaborative project.
J. Mol. Diagn. 20:703-715(2018)

Cross-references
Cell line collections (Providers) Coriell; GM11589
Coriell; GM17057
Cell line databases/resources CLO; CLO_0014660
CLO; CLO_0021205
Encyclopedic resources Wikidata; Q54845175
Entry history
Entry creation05-Nov-2013
Last entry update30-Jan-2024
Version number18