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Cellosaurus CCC-5 (CVCL_LM83)

[Text version]
Cell line name CCC-5
Synonyms CCC5
Accession CVCL_LM83
Resource Identification Initiative To cite this cell line use: CCC-5 (RRID:CVCL_LM83)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 60.5 hours (CelloPub=CLPUB00408); 2-3 days (DSMZ=ACC-810).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (DepMap=ACH-002647).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (CelloPub=CLPUB00408).
Disease Cholangiocarcinoma (NCIt: C4436)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-810

Markers:
AmelogeninX
CSF1PO10,11
D2S133820,25
D3S135814,17
D5S81811,13
D7S82010,11
D8S117914,15
D13S31712
D16S53911,12
D18S5115
D19S43314
D21S1129,31
FGA24
Penta D9,10
Penta E13,14
TH016,9.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Publications

CLPUB00408
Zach S., Grun J., Bauer A.T., Pilarsky C., Grutzmann R., Weng H.-L., Dooley S., Wilhelm T.J., Gaiser T., Ruckert F.
CCC-5, a new primary cholangiocellular cell line.
Int. J. Clin. Exp. Pathol. 10:2451-2460(2017)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) DSMZ; ACC-810
Cell line databases/resources cancercelllines; CVCL_LM83
DepMap; ACH-002647
DSMZCellDive; ACC-810
Encyclopedic resources Wikidata; Q54808767
Entry history
Entry creation15-Nov-2017
Last entry update02-May-2024
Version number12