ID   CHO-K1 tsTM13
AC   CVCL_LH73
SY   tsTM13
DR   Wikidata; Q54973161
RX   PubMed=1309502;
RX   PubMed=2237640;
RX   PubMed=8944784;
CC   Characteristics: Temperature sensitive. Exhibits a delayed cell cycle progression from metaphase to telophase at a non-permissive temperature of 39 Celsius and is finally arrested from anaphase to telophase.
CC   Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 15-11-17; Last updated: 30-01-24; Version: 8
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RX   PubMed=1309502; DOI=10.1016/0014-4827(92)90372-F;
RA   Tsuji H., Matsudo Y., Ajiro K., Yasuda H., Hanaoka F., Hayashi A.,
RA   Utsumi S., Ohba Y., Hori T.-a.;
RT   "A temperature-sensitive CHO-K1 cell mutant (tsTM13) defective in
RT   chromosome decondensation and spindle deconstruction in M phase.";
RL   Exp. Cell Res. 198:201-213(1992).
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RX   PubMed=2237640; DOI=10.1007/BF01233196;
RA   Tsuji H., Matsudo Y., Tsuji S., Hanaoka F., Hyodo M., Hori T.-a.;
RT   "Isolation of temperature-sensitive CHO-K1 cell mutants exhibiting
RT   chromosomal instability and reduced DNA synthesis at nonpermissive
RT   temperature.";
RL   Somat. Cell Mol. Genet. 16:461-476(1990).
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RX   PubMed=8944784; DOI=10.1111/j.1432-1033.1996.00923.x;
RA   Ajiro K., Yasuda H., Tsuji H.;
RT   "Vanadate triggers the transition from chromosome condensation to
RT   decondensation in a mitotic mutant (tsTM13) inactivation of p34cdc2/H1
RT   kinase and dephosphorylation of mitosis-specific histone H3.";
RL   Eur. J. Biochem. 241:923-930(1996).
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