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Cellosaurus PeTa (CVCL_LC73)

[Text version]
Cell line name PeTa
Synonyms PETA
Accession CVCL_LC73
Resource Identification Initiative To cite this cell line use: PeTa (RRID:CVCL_LC73)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 2-3 days (PubMed=30873613).
Transformant: NCBI_TaxID; 493803; Merkel cell polyomavirus (MCPyV).
Omics: Array-based CGH.
Omics: Deep quantitative proteome analysis.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Disease Merkel cell carcinoma (NCIt: C9231)
Cutaneous neuroendocrine carcinoma (ORDO: Orphanet_79140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): PubMed=30873613

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135814,15
D5S81812
D7S8209,13
D8S117914,15
D13S3178,12
D16S53911,12
D18S5115,16
D21S1130.2,32
FGA19,21
Penta D11,13
Penta E10,16
TH016,9
TPOX8
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=23563200; DOI=10.1038/jid.2013.169
Houben R., Dreher C., Angermeyer S., Borst A., Utikal J.S., Haferkamp S., Peitsch W.K., Schrama D., Hesbacher S.
Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens.
J. Invest. Dermatol. 133:2453-2460(2013)

PubMed=27121059; DOI=10.18632/oncotarget.8793; PMCID=PMC5078066
Hesbacher S., Pfitzer L., Wiedorfer K., Angermeyer S., Borst A., Haferkamp S., Scholz C.-J., Wobser M., Schrama D., Houben R.
RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.
Oncotarget 7:32956-32968(2016)

PubMed=30873613; DOI=10.1002/ijc.32280
Schrama D., Sarosi E.-M., Adam C., Ritter C., Kaemmerer U., Klopocki E., Konig E.-M., Utikal J.S., Becker J.C., Houben R.
Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: integration pattern suggest that large T antigen truncating events occur before or during integration.
Int. J. Cancer 145:1020-1032(2019)

PubMed=31889939; DOI=10.1186/s12014-019-9263-z; PMCID=PMC6921584
Kotowski U., Erovic B.M., Schnoll J., Stanek V., Janik S., Steurer M., Mitulovic G.
Quantitative proteome analysis of Merkel cell carcinoma cell lines using SILAC.
Clin. Proteomics 16:42.1-42.13(2019)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01848
DepMap; ACH-001170
Encyclopedic resources Wikidata; Q54947234
Proteomic databases PRIDE; PXD008181
Entry history
Entry creation22-Aug-2017
Last entry update29-Jun-2023
Version number7