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Cellosaurus COS-1/B2T.cl.17 (CVCL_FA30)

[Text version]
Cell line name COS-1/B2T.cl.17
Accession CVCL_FA30
Resource Identification Initiative To cite this cell line use: COS-1/B2T.cl.17 (RRID:CVCL_FA30)
Comments Group: Non-human primate cell line.
Characteristics: Transfected with a TNFRSF13C-TNFRSF1A (BAFFR-TNFR1) hybrid receptor containing the extracellular BAFF-binding portion of the TNFRSF13C and the intracellular signaling portion of TNFRSF1A.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 17755; TNFRSF13C (Note=AA 1-78).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11916; TNFRSF1A (Note=AA 204-443).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV6-1).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534)
Hierarchy Parent: CVCL_0223 (COS-1)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=24709903; DOI=10.3390/cells3010079; PMCID=PMC3980743
Hu J., Yu Y.-B., Han H., Civoli F., Zhuang Y., Thomas J., Swanson S., Jing S.-Q., Gupta S.
Development of a novel BAFF responsive cell line suitable for detecting bioactive BAFF and neutralizing antibodies against BAFF-pathway inhibiting therapeutics.
Cells 3:79-91(2014)

Cross-references
Encyclopedic resources Wikidata; Q54814312
Entry history
Entry creation26-Sep-2016
Last entry update10-Sep-2024
Version number10