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Cellosaurus JVE015 (CVCL_EG16)

[Text version]
Cell line name JVE015
Synonyms JVE-015
Accession CVCL_EG16
Resource Identification Initiative To cite this cell line use: JVE015 (RRID:CVCL_EG16)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~3-4 days (DSMZ=ACC-786).
Microsatellite instability: Stable (MSS) (PubMed=26894854).
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Arg1114Ter (c.3340C>T); ClinVar=VCV000236589; Zygosity=Heterozygous (PubMed=26894854; DepMap=ACH-002654).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=26894854; DepMap=ACH-002654).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Homozygous (DepMap=ACH-002654).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-786; PubMed=26894854

Markers:
AmelogeninX
CSF1PO12
D2S133818,19
D3S135816
D5S81811,12
D7S8209,11
D8S117913
D13S31711,12
D16S5399
D18S5115
D19S43313,14
D21S1130 (PubMed=26894854)
30,32.2 (DSMZ=ACC-786)
FGA23
Penta D11
Penta E11,12
TH016,9.3
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=26894854; DOI=10.18632/oncotarget.7391; PMCID=PMC4924731
Boot A., van Eendenburg J.D.H., Crobach S., Ruano D., Speetjens F., Calame J., Oosting J., Morreau H., van Wezel T.
Characterization of novel low passage primary and metastatic colorectal cancer cell lines.
Oncotarget 7:14499-14509(2016)

PubMed=28931069; DOI=10.1371/journal.pone.0184900; PMCID=PMC5607170
Boot A., Oosting J., van Eendenburg J.D.H., Kuppen P.J.K., Morreau H., van Wezel T.
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
PLoS ONE 12:E0184900-E0184900(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-786
Cell line databases/resources cancercelllines; CVCL_EG16
DepMap; ACH-002654
DSMZCellDive; ACC-786
Encyclopedic resources Wikidata; Q54899171
Gene expression databases GEO; GSM1655597
GEO; GSM1655623
Entry history
Entry creation13-Jul-2016
Last entry update02-May-2024
Version number14