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Cellosaurus PGF (CVCL_E806)

[Text version]
Cell line name PGF
Synonyms pGF; GM03107; GM3107
Accession CVCL_E806
Resource Identification Initiative To cite this cell line use: PGF (RRID:CVCL_E806)
Comments Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Population: Caucasian; English.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: MHC region genome.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=11248
Class I
HLA-AA*03:01:01:01
HLA-BB*07:02:01:01
HLA-CC*07:02:01:03
Class II
HLA-DPDPA1*01:03:01:02
DPB1*04:01:01
HLA-DQDQA1*01:02:01:05
DQB1*06:02:01
HLA-DRDRB1*15:01:01
DRB5*01:01:01
DRB6*02:01

Source: PubMed=30844424
Class I
HLA-AA*03:01:01:01
HLA-BB*07:02:01
HLA-CC*07:02:01:03
Class II
HLA-DPDPA1*01:03:01:02
DPB1*04:01:01:01
HLA-DQDQA1*01:02:01
DQB1*06:02:01
HLA-DRDRB1*15:01:01
DRB5*01:01:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=6200433; DOI=10.1007/BF00364762
Brodsky F.M.
A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes.
Immunogenetics 19:179-194(1984)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=15140828; DOI=10.1101/gr.2188104; PMCID=PMC419796
Stewart C.A., Horton R., Allcock R.J.N., Ashurst J.L., Atrazhev A.M., Coggill P., Dunham I., Forbes S., Halls K., Howson J.M.M., Humphray S.J., Hunt S., Mungall A.J., Osoegawa K., Palmer S., Roberts A.N., Rogers J., Sims S., Wang Y., Wilming L.G., Elliott J.F., de Jong P.J., Sawcer S., Todd J.A., Trowsdale J., Beck S.
Complete MHC haplotype sequencing for common disease gene mapping.
Genome Res. 14:1176-1187(2004)

PubMed=16440057; DOI=10.1371/journal.pgen.0020009; PMCID=PMC1331980
Traherne J.A., Horton R., Roberts A.N., Miretti M.M., Hurles M.E., Stewart C.A., Ashurst J.L., Atrazhev A.M., Coggill P., Palmer S., Almeida-King J., Sims S., Wilming L.G., Rogers J., de Jong P.J., Carrington M.N., Elliott J.F., Sawcer S., Todd J.A., Trowsdale J., Beck S.
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.
PLoS Genet. 2:E9-E9(2006)

PubMed=16702430; DOI=10.1534/genetics.106.057034; PMCID=PMC1526686
Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M., Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K., Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A., Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T., Inoko H., Bahram S.
Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
Genetics 173:1555-1570(2006)

PubMed=18193213; DOI=10.1007/s00251-007-0262-2; PMCID=PMC2206249
Horton R., Gibson R., Coggill P., Miretti M.M., Allcock R.J.N., Almeida-King J., Forbes S., Gilbert J.G.R., Halls K., Harrow J.L., Hart E., Howe K.L., Jackson D.K., Palmer S., Roberts A.N., Sims S., Stewart C.A., Traherne J.A., Trevanion S., Wilming L.G., Rogers J., de Jong P.J., Elliott J.F., Sawcer S., Todd J.A., Trowsdale J., Beck S.
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project.
Immunogenetics 60:1-18(2008)

PubMed=28360230; DOI=10.1101/gr.213538.116; PMCID=PMC5411776
Norman P.J., Norberg S.J., Guethlein L.A., Nemat-Gorgani N., Royce T., Wroblewski E.E., Dunn T., Mann T., Alicata C., Hollenbach J.A., Chang W.-H., Shults Won M., Gunderson K.L., Abi-Rached L., Ronaghi M., Parham P.
Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.
Genome Res. 27:813-823(2017)

PubMed=29171935; DOI=10.1111/tan.13184
Turner T.R., Hayhurst J.D., Hayward D.R., Bultitude W.P., Barker D.J., Robinson J., Madrigal J.A., Mayor N.P., Marsh S.G.E.
Single molecule real-time DNA sequencing of HLA genes at ultra-high resolution from 126 international HLA and immunogenetics workshop cell lines.
HLA 91:88-101(2018)

PubMed=30844424; DOI=10.1016/j.humimm.2019.03.001; PMCID=PMC6599558
Creary L.E., Guerra S.G., Chong W., Brown C.J., Turner T.R., Robinson J., Bultitude W.P., Mayor N.P., Marsh S.G.E., Saito K., Lam K., Duke J.L., Mosbruger T.L., Ferriola D., Monos D.S., Willis A., Askar M., Fischer G.F., Saw C.L., Ragoussis J., Petrek M., Serra-Pages C., Juan Otero M., Stavropoulos-Giokas C., Dinou A., Ameen R., Al Shemmari S., Spierings E., Gendzekhadze K., Morris G.P., Zhang Q.-H., Kashi Z., Hsu S., Gangavarapu S., Mallempati K.C., Yamamoto F., Osoegawa K., Vayntrub T., Chang C.-J., Hansen J.A., Fernandez-Vina M.A.
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop.
Hum. Immunol. 80:449-460(2019)

Cross-references
Cell line collections (Providers) Coriell; GM03107
ECACC; 94050342
Cell line databases/resources CLO; CLO_0013567
dbMHC; 49001
IHW; IHW09318
IPD-IMGT/HLA; 11248
Encyclopedic resources Wikidata; Q54947326
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number19