ID   Raji-TG
AC   CVCL_DD98
DR   cancercelllines; CVCL_DD98
DR   Wikidata; Q54949153
RX   PubMed=844867;
CC   Population: African; Nigerian.
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Sequence variation: Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0511 ! Raji
SX   Male
AG   11Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 02-05-24; Version: 17
//
RX   PubMed=844867; DOI=10.1007/BF00393971;
RA   Yoshida M.C., Kodama Y.;
RT   "Karyological characterization of a human lymphoblastoid cell line
RT   resistant to 6-thioguanine.";
RL   Hum. Genet. 35:201-208(1977).
//