Cellosaurus logo
expasy logo

Cellosaurus HeLa Flp-In T-REx PINK1 KO clone 3C9 (CVCL_D5JI)

[Text version]
Cell line name HeLa Flp-In T-REx PINK1 KO clone 3C9
Synonyms Flp-In T-Rex HeLa PINK1 CRISPR/Cas9 knock-out
Accession CVCL_D5JI
Resource Identification Initiative To cite this cell line use: HeLa Flp-In T-REx PINK1 KO clone 3C9 (RRID:CVCL_D5JI)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; 14581; PINK1.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
Transfected with: UniProtKB; P00722; Escherichia coli lacZ.
Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C4ET (HeLa Flp-In T-REx)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=35042401; DOI=10.1098/rsob.210264
Kakade P.S., Ojha H., Raimi O.G., Shaw A., Waddell A.D., Ault J.R., Burel S., Brockmann K., Kumar A., Ahangar M.S., Krysztofinska E.M., Macartney T., Bayliss R., Fitzgerald J.C., Muqit M.M.K.
Mapping of a N-terminal alpha-helix domain required for human PINK1 stabilization, serine228 autophosphorylation and activation in cells.
Open Biol. 12:210264.1-210264.16(2022)

Entry history
Entry creation02-May-2024
Last entry update02-May-2024
Version number1