Cellosaurus A549-AC (CVCL_D1JI)
Cell line name | A549-AC |
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Accession | CVCL_D1JI |
Resource Identification Initiative | To cite this cell line use: A549-AC (RRID:CVCL_D1JI) |
Comments | Group: SARS-CoV-2 research cell line. Population: Caucasian. Characteristics: Expresses ACE2 under the control of the EF1a promoter (from parent cell line). Characteristics: Tranduced with a EF1a-Cas9-2A-eGFP vector (PubMed=36032971). Transfected with: HGNC; 13557; ACE2. Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP). Transfected with: UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd). Omics: CRISPR phenotypic screen. Derived from site: In situ; Lung; UBERON=UBERON_0002048. |
Sequence variations |
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Disease | Lung adenocarcinoma (NCIt: C3512) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_A7UV (A549-hACE2 [BEI resources]) |
Sex of cell | Male |
Age at sampling | 58Y |
Category | Cancer cell line |
Publications | PubMed=36032971; DOI=10.21203/rs.3.rs-1910932/v1 |
Entry history | |
Entry creation | 30-Jan-2024 |
Last entry update | 30-Jan-2024 |
Version number | 1 |