Cellosaurus RPE1-SS111 (CVCL_C8DM)
Cell line name | RPE1-SS111 |
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Synonyms | RPE1SS111 |
Accession | CVCL_C8DM |
Resource Identification Initiative | To cite this cell line use: RPE1-SS111 (RRID:CVCL_C8DM) |
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Characteristics: This cell line has a stable aneuploid karyotype, the parent cell line was transiently treated with the TTK inhibitor reversine to induce random chromosome gains and losses (PubMed=33505028). Karyotypic information: Contains extra Chr 8, Chr 9 and Chr 18 (PubMed=33505028). Genetic integration: Method=Transfection; Gene=HGNC; 11730; TERT. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782. Cell type: Retinal pigment epithelial cell; CL=CL_0002586. |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_4388 (hTERT-RPE1) |
Sex of cell | Female |
Age at sampling | 1Y |
Category | Telomerase immortalized cell line |
Publications | PubMed=33505028; DOI=10.1038/s41586-020-03114-6; PMCID=PMC8262644 |
Cross-references | |
Cell line databases/resources | DepMap; ACH-002466 |
Encyclopedic resources | Wikidata; Q123033369 |
Entry history | |
Entry creation | 29-Jun-2023 |
Last entry update | 10-Sep-2024 |
Version number | 4 |