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Cellosaurus HS181 EGFP-2A-RUNX1c (CVCL_A8HS)

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Cell line name HS181 EGFP-2A-RUNX1c
Synonyms HS181 pRRL-EF1a-EGFP-2A-RUNX1c-PGK-Neo
Accession CVCL_A8HS
Resource Identification Initiative To cite this cell line use: HS181 EGFP-2A-RUNX1c (RRID:CVCL_A8HS)
Comments Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
From: Centre for Genomics and Oncological Research (GENYO); Granada; Spain.
Characteristics: Transduced with a pRRL-EF1a-EGFP-2A-RUNX1c-PGKp-Neo construct.
Genetic integration: Method=Transduction; Gene=HGNC; 10471; RUNX1 (Note=Isoform AML-1C).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C229 (HS181)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20embrionarias/Attachments/34/Caracteristicas%20-%20Solicitud_Deposito_linea_HS18_RUNX1c.pdf
https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20embrionarias/Attachments/34/Anexo%20-%20Anexo_HS181_RUNXc-2.pdf
Publications

PubMed=28869683; DOI=10.1002/stem.2700
Navarro-Montero O., Ayllon V., Lamolda M., Lopez-Onieva L., Montes R., Bueno C., Ng E.S., Guerrero-Carreno X., Romero T., Romero-Moya D., Stanley E.G., Elefanty A.G., Ramos-Mejia V., Menendez P., Real P.J.
RUNX1c regulates hematopoietic differentiation of human pluripotent stem cells possibly in cooperation with proinflammatory signaling.
Stem Cells 35:2253-2266(2017)

Cross-references
Encyclopedic resources Wikidata; Q107115363
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number5